Based on the SMILES COC(=O)Nc1nc2cc(C(=O)c3ccccc3)ccc2[nH]1, the molecule is not metabolized by CYP P450 3A4.
Based on the {SMILES__description} {#representation |!}{SMILES#}, the molecule is {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}.