User: Can you generate the SMILES of a molecule that is a not substrate for CYP3A4?
Assistant: Of course, here you go: C[C@@H]1CC[C@H]2[C@@H](C)[C@@H](OC(=O)CCC(=O)O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4
User: Can you {#give me|create|generate!} the {SMILES__description} of a molecule that is a {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__noun}?
Assistant: {#Yes|Of course|Sure|Yes, I'm happy to help!}, here you go: {SMILES#}