Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
(a) COC(=O)Nc1nc2cc(C(=O)c3ccccc3)ccc2[nH]1
(b) Cc1ccc(C(=O)[C@H](C)CN2CCCCC2)cc1
(c) CC(C)NC[C@H](O)COc1ccc(COCCOC(C)C)cc1
Answer: a, b
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}