Task: Please answer the multiple choice question.
Question: Which molecules are a substrate for CYP3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1cc(N)c(Cl)cc1C(=O)N[C@H]1CCN(CCCOc2ccc(F)cc2)C[C@H]1OC
b: CNC(=O)Oc1cc(C)c(SC)c(C)c1
c: C#CCN(C)[C@@H](C)Cc1ccccc1
d: O=C(O)c1ccc(OCCn2ccnc2)cc1
e: CC[C@H](C)n1ncn(-c2ccc(N3CCN(c4ccc(OC[C@H]5CO[C@](Cn6cncn6)(c6ccc(Cl)cc6Cl)O5)cc4)CC3)cc2)c1=O
Answer: a, b, c, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}