Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a CC(C)(C)NC[C@@H](O)c1ccc(O)c(CO)c1
b CCCCCN(CCCOC)C(=O)[C@@H](CCC(=O)O)NC(=O)c1ccc(Cl)c(Cl)c1
c O=C(C1CCCCC1)N1CC(=O)N2CCc3ccccc3[C@H]2C1
d C[C@@H]1CC[C@H]2[C@@H](C)[C@@H](OC(=O)CCC(=O)O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@@]23OO4
Answer: a, b, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}