Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a COCCc1ccc(OC[C@@H](O)CNC(C)C)cc1
b C[C@@H](C(=O)O)c1cccc(C(=O)c2ccccc2)c1
c c1ccccc1
d CC(C)(Oc1ccc(Cl)cc1)C(=O)O
Answer: a, b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}