Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C(N[C@H](CO)[C@H](O)c1ccc([N+](=O)[O-])cc1)C(Cl)Cl
b CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21
c CN1CCN2c3ccccc3Cc3ccccc3[C@@H]2C1
d C#C[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@@]21C
e COCCc1ccc(OC[C@@H](O)CNC(C)C)cc1
Answer: a, b, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}