Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
[a] CCC(=O)O[C@](Cc1ccccc1)(c1ccccc1)[C@H](C)CN(C)C
[b] O=C(O)c1ccccc1O
[c] Cc1cc(Cl)c(S(N)(=O)=O)cc1S(N)(=O)=O
Answer: a, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}