Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. O=C(Cn1c(=O)sc2ccc(Cl)cc21)N1CCN(CCO)CC1
b. CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN[C@H](C)C3)c(F)c21
c. C[C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@H]2O
d. C[C@@H](NC(C)(C)C)C(=O)c1cccc(Cl)c1
Answer: a, b
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}