Task: Please answer the multiple choice question.
Question: Which molecules are a CYP3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] C#C[C@]1(O)CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@@]21C
[b] CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC
[c] CC(C)C(=O)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1
[d] CN1CC[C@@]23CCCC[C@@H]2[C@@H]1Cc1ccc(O)cc13
[e] COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)(C)CN(C)CCC(c2ccccc2)c2ccccc2)[C@H]1c1cccc([N+](=O)[O-])c1
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}