Task: Please answer the multiple choice question.
Question: Which molecules are a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. Nc1c(Br)cc(Br)cc1CNC1CCC(O)CC1
b. CN(C/C=C/C#CC(C)(C)C)Cc1cccc2ccccc12
c. CCN(CC)CC(=O)Nc1c(C)cccc1C
d. CCc1nn(CCCN2CCN(c3cccc(Cl)c3)CC2)c(=O)n1CCOc1ccccc1
e. CN(C)[C@@H]1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3C[C@@H]12
Answer: a, b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}