Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CCN(CC)CCC[C@H](C)Nc1ccnc2cc(Cl)ccc12
b CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O
c CCCC(=O)Nc1ccc(OC[C@@H](O)CNC(C)C)c(C(C)=O)c1
d CCN(CCO)CCC[C@H](C)Nc1ccnc2cc(Cl)ccc12
e CCCCc1ncc(/C=C(/Cc2cccs2)C(=O)O)n1Cc1ccc(C(=O)O)cc1
Answer: c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}