User: Can you create the SMILES of a molecule that is a not substrate for CYP P450 3A4?
Assistant: Yes, I'm happy to help, here you go: CC[C@@H]1NC(=O)[C@@H](NC(=O)c2ncccc2O)[C@@H](C)OC(=O)[C@H](c2ccccc2)NC(=O)[C@@H]2CC(=O)[C@H](CS[C@@H]3CN4CCC3CC4)CN2C(=O)[C@H](Cc2ccc(N(C)C)cc2)N(C)C(=O)[C@@H]2CCCN2C1=O
User: Can you {#give me|create|generate!} the {SMILES__description} of a molecule that is a {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__noun}?
Assistant: {#Yes|Of course|Sure|Yes, I'm happy to help!}, here you go: {SMILES#}