Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP3A4 substrate?
Constraint: You must select none, one or more options from a or b without using any other words.
Options:
(a) COCCc1ccc(OC[C@@H](O)CNC(C)C)cc1
(b) CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O
Answer: a
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}