Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
(a) Cc1ccc(Cl)c(OC[C@@H](O)CNC(C)(C)C)c1
(b) Cc1cnc(NC(=O)C2=C(O)c3ccccc3S(=O)(=O)N2C)s1
(c) CN(C/C=C/C#CC(C)(C)C)Cc1cccc2ccccc12
Answer: a
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}