Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc2cc([C@H](C)C(=O)O)ccc2c1
(b) CNC(=O)Oc1cccc2ccccc12
(c) CSc1ccc2c(c1)N(CC[C@@H]1CCCCN1C)c1ccccc1S2
(d) CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc21
(e) CC(C)(C)NC[C@@H](O)c1ccc(O)c(CO)c1
Answer: a, c, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}