Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CNC[C@H](O)c1ccc(O)c(O)c1
b: CC(C)(C)c1cc(C[C@H]2SCNC2=O)cc(C(C)(C)C)c1O
c: CCOP(=S)(OCC)Oc1ccc([N+](=O)[O-])cc1
d: COC(=O)Nc1nc2cc(C(=O)c3ccccc3)ccc2[nH]1
e: CCC(=O)O[C@](Cc1ccccc1)(c1ccccc1)[C@H](C)CN(C)C
Answer: a, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}