Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a: CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1
b: CNCCCC12CCC(c3ccccc31)c1ccccc12
c: Cc1cc(N(C)C)ccc1C[C@H](C)N
Answer: b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}