Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a: COCCCC/C(=N/OCCN)c1ccc(C(F)(F)F)cc1
b: CC(C)(Oc1ccc(Cl)cc1)C(=O)O
c: NCC[C@@H](Oc1ccc(C(F)(F)F)cc1)c1ccccc1
Answer: a, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}