Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a CCN(CCO)CCC[C@H](C)Nc1ccnc2cc(Cl)ccc12
b O=C(O)c1ccc(OCCn2ccnc2)cc1
c CC(C)(C)NC[C@H](O)COc1ccccc1C#N
d c1ccccc1
Answer: a, b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}