User: I want to come up with a molecule SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the generation?
User: Yes, please. The molecule should not be metabolized by CYP P450 3A4.
Assistant: Got it, here you go, this SMILES is not metabolized by CYP P450 3A4: CC[C@@H]1NC(=O)[C@@H](NC(=O)c2ncccc2O)[C@@H](C)OC(=O)[C@H](c2ccccc2)NC(=O)[C@@H]2CC(=O)[C@H](CS[C@@H]3CN4CCC3CC4)CN2C(=O)[C@H](Cc2ccc(N(C)C)cc2)N(C)C(=O)[C@@H]2CCCN2C1=O
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {CYP3A4_Substrate#not &NULL}be {CYP3A4_Substrate__names__verb}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}: {SMILES#}