User: I want to create a SMILES.
Assistant: This sounds very exciting. Should it be a special molecule?
User: Yes, the molecule should not be a substrate for CYP P450 3A4.
Assistant: Got it, this SMILES is not a substrate for CYP P450 3A4: COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(Cc1ccc(-c2ccccn2)cc1)NC(=O)[C@H](NC(=O)OC)C(C)(C)C)C(C)(C)C
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should it be a special {#molecule|one!}?
User: Yes, the molecule should {CYP3A4_Substrate#not &NULL}be a {CYP3A4_Substrate__names__noun}.
Assistant: {#Understood|Got it|Ok!}, this {SMILES__description} is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}: {SMILES#}