Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a) CCN(CCO)CCC[C@H](C)Nc1ccnc2cc(Cl)ccc12
b) CC(C)(C)NC[C@H](O)COc1ccccc1C#N
c) CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc21
Answer: a, b
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}