User: Is the molecule with the SMILES CO[C@@]12[C@H](COC(N)=O)C3=C(C(=O)C(C)=C(N)C3=O)N1C[C@@H]1N[C@@H]12 toxic in the p53 response assay?
Assistant: Yes, it is toxic in the p53 response assay.
User: Is the molecule with the {SMILES__description} {SMILES#} {toxicity_SR-p53__names__adjective}?
Assistant: {toxicity_SR-p53#No&Yes}, it is {toxicity_SR-p53#not &NULL}{toxicity_SR-p53__names__adjective}.