User: Is the molecule with the SMILES C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3CC[C@@]21C metabolized by CYP P450 2C9?
Assistant: No, it is not a CYP2C9 substrate.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP2C9_Substrate__names__verb}?
Assistant: {CYP2C9_Substrate#No&Yes}, it is {CYP2C9_Substrate#not &NULL}a {CYP2C9_Substrate__names__noun}.