The SMILES COC(=O)C1=C(C(=O)OC)SC(=CC#CC=C2SC(C(=O)OC)=C(C(=O)OC)S2)S1 is not active against HIV.
The {#molecule |!}{SMILES__description} {SMILES#} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}.