Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCCN(CCC)c1nc2ccccc2nc1C(C#N)C(=O)OC(C)COC
(b) Cn1c(=O)oc2cc(S(=O)(=O)N3CCN(C(=O)c4ccco4)CC3)ccc21
(c) CCOC(=O)c1c(-c2ccccc2)nnn1-c1nc(OCC)nc(N2CCCCC2)n1
(d) O=C(c1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1)N1CCN(c2ccc(F)cc2)CC1
(e) CCCCN(CC)CCCNC(=O)c1cc2cc3ccc(OC)cc3nc2o1
Answer: a, b, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}