Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. O=C(COC(=O)c1ccc2c(c1)OCO2)NCc1ccc(Cl)cc1
b. Cn1c(-c2ccc3nc(N)sc3c2)nc2cc(N)ccc21
c. Cc1cc(=O)nc(N2CCN(Cc3ccccc3)CC2)[nH]1
d. COc1cc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2cc(C)on2)cc(Br)c1O
e. COc1ccc(C2C(C(N)=O)=C(C)N=C3N=CNN32)cc1
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}