Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCc1ccc(NC(=O)C2CC(=O)N=C(N)S2)cc1
b. COc1ccc(OC)c(C(=O)c2coc3ccc(O)c(CN4CCOCC4)c23)c1
c. Cc1ccc(C(=O)CCNc2ccc(Br)cc2)o1
d. CN1C(=O)C2(C(C#N)=C(N)Oc3n[nH]c(-c4ccc(Cl)cc4)c32)c2ccccc21
e. Clc1ccc2nc(N3CCNCC3)nc(-c3ccccc3)c2c1
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}