Task: Please determine if the molecule with the SMILES COc1ccc(OC)c(C2NC(=O)NC(C)=C2C(=O)Nc2ccc(C)cc2)c1 is an allosteric modulator of the dopamine receptor D1.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-858__names__noun}.
Result: {MUV-858#no&yes}
COc1ccc(OC)c(C2NC(=O)NC(C)=C2C(=O)Nc2ccc(C)cc2)c1
COc1ccc(OC)c(C2NC(=O)NC(C)=C2C(=O)Nc2ccc(C)cc2)c1
4-(2,5-dimethoxyphenyl)-6-methyl-N-(4-methylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide