Task: Please determine if the molecule with the SMILES COC(=O)C1CCN(Cc2cc(=O)oc3cc(OC)ccc23)CC1 is an allosteric modulator of the D1 receptor.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-858__names__noun}.
Result: {MUV-858#no&yes}
COC(=O)C1CCN(Cc2cc(=O)oc3cc(OC)ccc23)CC1
COC(=O)C1CCN(Cc2cc(=O)oc3cc(OC)ccc23)CC1
methyl 1-[(7-methoxy-2-oxochromen-4-yl)methyl]piperidine-4-carboxylate