User: I want to generate a SMILES.
Assistant: This sounds very exciting. Should I consider any specific points for the creation?
User: Yes, please. The molecule can be described by:
The molecule is the intermediate in the biosynthesis of vitamin B12 from uroporphyrinogen III in which three methyl groups have been introduced at positions 2, 7 and 20 of the tetrapyrrole framework and in which the carboxymethyl group at position 2 has been oxidised to form a lactone ring. It is a conjugate acid of a precorrin-3B(7-) and a precorrin-3B(6-).
Assistant: Got it, here you go, this SMILES fits this description: C[C@]1(O)c2[nH]c(c(CCC(=O)O)c2CC(=O)O)Cc2[nH]c(c(CC(=O)O)c2CCC(=O)O)/C=C2\N/C(=C\C3=N[C@]14OC(=O)C[C@@]4(C)[C@@H]3CCC(=O)O)[C@@](C)(CC(=O)O)[C@@H]2CCC(=O)O
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule can be described {#by|as!}:
{description#}
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} fits {#your|this!} description: {SMILES#}
C[C@]1(O)c2[nH]c(c(CCC(=O)O)c2CC(=O)O)Cc2[nH]c(c(CC(=O)O)c2CCC(=O)O)/C=C2\N/C(=C\C3=N[C@]14OC(=O)C[C@@]4(C)[C@@H]3CCC(=O)O)[C@@](C)(CC(=O)O)[C@@H]2CCC(=O)O
3-[(1R,2S,12Z,14S,15S,16Z,19S,20S)-5,9,19-tris(2-carboxyethyl)-4,10,15-tris(carboxymethyl)-2-hydroxy-2,15,20-trimethyl-22-oxo-23-oxa-24,25,26,27-tetrazahexacyclo[16.5.1.13,6.18,11.113,16.01,20]heptacosa-3,5,8,10,12,16,18(24)-heptaen-14-yl]propanoic acid
The molecule is the intermediate in the biosynthesis of vitamin B12 from uroporphyrinogen III in which three methyl groups have been introduced at positions 2, 7 and 20 of the tetrapyrrole framework and in which the carboxymethyl group at position 2 has been oxidised to form a lactone ring. It is a conjugate acid of a precorrin-3B(7-) and a precorrin-3B(6-).