Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. OC(c1ccccc1)(c1ccccc1)C1CCNCC1
b. CCO
c. c1ccc2cc(COC3CCNCC3)ccc2c1
d. O=c1[nH]cc(F)c(=O)[nH]1
e. CC(C)NC[C@H](O)COc1cccc2[nH]ccc12
Answer: a, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}