Based on the SMILES representation Nc1nc2ccc(OC(F)(F)F)cc2s1, the molecule is not metabolized by CYP P450 3A4.
Based on the {SMILES__description} {#representation |!}{SMILES#}, the molecule is {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}.