Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CC[C@]1(C)CC(=O)NC1=O
(b) CCC(C)(C)NC[C@H](O)COc1ccccc1C(=O)CCc1ccccc1
(c) CN1CCC[C@H](n2nc(Cc3ccc(Cl)cc3)c3ccccc3c2=O)CC1
(d) NNC(=O)c1ccncc1
(e) CN(CCOc1ccc(C[C@@H]2SC(=O)NC2=O)cc1)c1ccccn1
Answer: b, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}