Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a CN1CCN=C(c2ccccc2)c2cc(Cl)ccc21
b CN[C@@H]1CCc2[nH]c3ccc(C(N)=O)cc3c2C1
c OCCOCCN1CCN(C2=Nc3ccccc3Sc3ccccc32)CC1
Answer: a, b
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}