Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@@H]4[C@H]3C(=C)C[C@@]21CC
(b) CCC(=O)O[C@]1(C(=O)SCF)[C@H](C)C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C
(c) CCCC(CCC)C(=O)O
(d) CC[C@@H]1C(=O)OC[C@@H]1Cc1cncn1C
(e) Cc1cccc(C)c1NC(=O)CC12CCCN1CCC2
Answer: c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}