Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C=C(Cl)C4=CC(=O)[C@@H]5C[C@@H]5[C@]4(C)[C@H]3CC[C@@]21C
b) COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
c) Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1
d) CC[C@@H]1[C@@H]2C[C@H]3[C@@H]4N(C)c5ccccc5[C@]45C[C@@H]([C@H]2[C@H]5O)N3[C@@H]1O
Answer: b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}