The molecule with the SMILES COc1cc(C(=O)NS(=O)(=O)c2ccccc2C)ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12 is not a CYP P450 3A4 substrate.
The molecule with the {SMILES__description} {#representation of |!}{SMILES#} is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.