Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a: CCCO
b: CC(=O)C[C@@H](c1ccccc1)c1c(O)c2ccccc2oc1=O
c: COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1[C@@H](NC(C)=O)CC2
d: C[C@@H](C(=O)O)c1ccc2c(c1)CC(=O)c1ccccc1S2
Answer: a, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}