Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. O=c1[nH]cc(F)c(=O)[nH]1
b. CC(C)NC[C@H](O)COc1ccc(CCOCC2CC2)cc1
c. CCC[C@@](C)(COC(N)=O)COC(=O)NC(C)C
d. C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](O)c1ccnc2ccc(OC)cc12
e. Fc1cccc2c1O[C@H]1CNC[C@@H]1O2
Answer: a, b, c, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}