Task: Please answer the multiple choice question.
Question: Which molecules are metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C
(b) CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O
(c) CCc1nn(CCCN2CCN(c3cccc(Cl)c3)CC2)c(=O)n1CC
(d) O=[P@]1(N(CCCl)CCCl)NCCCO1
(e) C[C@@H](CCc1ccccc1)NC[C@H](O)c1ccc(O)c(C(N)=O)c1
Answer: a, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}