The molecule with the SMILES O=C(O)COc1ccc(C(=O)c2cccs2)c(Cl)c1Cl is not a CYP3A4 substrate.
The molecule with the {SMILES__description} {#representation of |!}{SMILES#} is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.