The molecule with the SMILES O=C1CC[C@H](N2C(=O)c3ccccc3C2=O)C(=O)N1 is not a CYP P450 3A4 substrate.
The molecule with the {SMILES__description} {#representation of |!}{SMILES#} is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.