Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CN1C(=O)[C@@](C)(C2=CCCCC2)C(=O)N=C1O
(b) CN1CCN(C2=Nc3cc(F)ccc3Cc3ccccc32)CC1
(c) N#Cc1ccc([C@H]2CCCc3cncn32)cc1
(d) NC(N)=Nc1nc(CSCC/C(N)=N\S(N)(=O)=O)cs1
(e) Cc1ncsc1CCCl
Answer: a, b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}