User: Is the molecule with the SMILES COc1cc([C@@H]2c3cc4c(cc3[C@@H](O[C@@H]3O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]3O)[C@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1O metabolized by CYP3A4?
Assistant: Yes, it is a substrate for CYP P450 3A4.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP3A4_Substrate__names__verb}?
Assistant: {CYP3A4_Substrate#No&Yes}, it is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.