Task: Please answer the multiple choice question.
Question: Which molecules are a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a. CNC(=O)c1cccc(NCC(=O)NCCc2ccc(OC)c(OC)c2)c1
b. O=C1Nc2ccc(Cl)cc2[C@@](C#CC2CC2)(C(F)(F)F)O1
c. Cc1cncc(CN2CCC(=C3c4ccc(Cl)cc4CCc4cccnc43)CC2)c1
Answer: a, b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}