Task: Please answer the multiple choice question.
Question: Which molecules are a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] C[C@@H](c1ncncc1F)[C@](O)(Cn1cncn1)c1ccc(F)cc1F
[b] CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1
[c] Cc1[nH]cnc1CN1CCc2c(c3ccccc3n2C)C1=O
[d] O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
[e] CN(C)CCC=C1c2ccccc2C=Cc2ccccc21
Answer: a, b, c, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}