User: Is the molecule with the SMILES C[C@@H](O[C@H]1OCCN(Cc2n[nH]c(=O)[nH]2)[C@H]1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 metabolized by CYP3A4?
Assistant: Yes, it is a CYP P450 3A4 substrate.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP3A4_Substrate__names__verb}?
Assistant: {CYP3A4_Substrate#No&Yes}, it is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.