Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a: CC(=O)C[C@@H](c1ccccc1)c1c(O)c2ccccc2oc1=O
b: O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
c: C[C@H](C(=O)O)c1cccc(C(=O)c2cccs2)c1
d: CCOC(=O)C1(c2ccccc2)CCN(C)CC1
Answer: b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}