Task: Please answer the multiple choice question.
Question: Which molecules are metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1cc(C(C)=O)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1
(b) Nc1nc(=O)c(Br)c(-c2ccccc2)[nH]1
(c) O=C1CN(/N=C\c2ccc(-c3ccc([N+](=O)[O-])cc3)o2)C(=O)N1
(d) COc1ccc(CCN(C)CCC[C@@](C#N)(c2ccc(OC)c(OC)c2)C(C)C)cc1OC
(e) COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC
Answer: a, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}