Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) Cn1nnc2ccc([C@H](c3ccc(Cl)cc3)n3cncn3)cc21
b.) O=c1[nH]c2ccccc2n1C1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1
c.) CC[C@@H]1C(=O)OC[C@@H]1Cc1cncn1C
d.) CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(S(N)(=O)=O)c1
Answer: a, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}