Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Cc1onc(-c2ccccc2)c1-c1ccc(S(N)(=O)=O)cc1
(b) CC(C)(C)NC[C@H](O)COc1ccccc1C1CCCC1
(c) CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1CC[C@@H](O)C[C@@H](O)CC(=O)O
(d) CN1C(=O)CC[C@H]1c1cccnc1
(e) CCn1cc(C(=O)O)c(=O)c2cnc(N3CCNCC3)nc21
Answer: b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}