Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c1ccnc2ccc(OC)cc12
(b) OCCN1CCN(CCCN2c3ccccc3C=Cc3ccccc32)CC1
(c) FCOC(C(F)(F)F)C(F)(F)F
(d) O=[P@@]1(N(CCCl)CCCl)OCCCN1CCCl
(e) Clc1cccc([C@H](c2ccc3nc[nH]c3c2)n2ccnc2)c1
Answer: a, b, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}