Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CC[C@H](c1ccccc1)c1c(O)c2ccccc2oc1=O
b C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)CO
c CN1C(=O)C[C@@H](c2ccccc2)C1=O
d OCc1cc([C@H](O)CNCCCCCCOCCCCc2ccccc2)ccc1O
e CCOCn1c(Cc2ccccc2)c(C(C)C)c(=O)[nH]c1=O
Answer: a, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}