Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C1NC(=O)C(c2ccccc2)(c2ccccc2)N1
b O=C(O)c1ccccc1Nc1cccc(C(F)(F)F)c1
c NS(=O)(=O)Cc1noc2ccccc12
d CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccccc1/C=C\C(=O)OC(C)(C)C
e CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O
Answer: a, b, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}