Based on the SMILES representation COC1=CC(=O)C[C@@H](C)[C@]12Oc1c(Cl)c(OC)cc(OC)c1C2=O, the molecule is not metabolized by CYP P450 3A4.
Based on the {SMILES__description} {#representation |!}{SMILES#}, the molecule is {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}.