Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C(OC1C[C@@H]2CC3C[C@H](C1)N2CC3=O)c1c[nH]c2ccccc12
[b] Nc1c2c(nc3ccccc13)CCCC2
[c] CCN(CC)C(=O)[C@]1(c2ccccc2)C[C@@H]1CN
[d] O=C1CN=C(c2ccccc2Cl)c2cc([N+](=O)[O-])ccc2N1
[e] CCc1nn(CCCN2CCN(c3cccc(Cl)c3)CC2)c(=O)n1CC
Answer: b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}