Task: Please answer the multiple choice question.
Question: Which molecules are a CYP3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O[C@@H](c1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12)[C@H]1CCCCN1
b) COC1=CC(=O)C[C@@H](C)[C@]12Oc1c(Cl)c(OC)cc(OC)c1C2=O
c) Cc1cccc(C)c1NC(=O)CN1CCCC1=O
d) CCOc1ccccc1OCCN[C@H](C)Cc1ccc(OC)c(S(N)(=O)=O)c1
e) Cc1noc(NS(=O)(=O)c2ccc(N)cc2)c1C
Answer: a, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}