User: I want to create a molecule SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be metabolized by CYP P450 3A4.
Assistant: Got it, this SMILES is not metabolized by CYP P450 3A4: COCc1c(C(=O)OC(C)C)ncc2[nH]c3ccc(OCc4ccccc4)cc3c12
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {CYP3A4_Substrate#not &NULL}be {CYP3A4_Substrate__names__verb}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}: {SMILES#}