Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CCOC(=O)C[C@@H](SP(=S)(OC)OC)C(=O)OCC
b: Nc1nc2ccc(OC(F)(F)F)cc2s1
c: O=C1[C@H]2CCCC[C@H]2C(=O)N1CCCCN1CCN(c2nsc3ccccc23)CC1
d: CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1CC[C@@H](O)C[C@@H](O)CC(=O)O
e: CNC(=O)c1cccc(NCC(=O)NCCc2ccc(OC)c(OC)c2)c1
Answer: a, b, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}