Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)[C@@H](C2)N(C)CC[C@]314
[b] COCc1c(C(C)C)nc(C(C)C)c(/C=C\[C@@H](O)C[C@@H](O)CC(=O)O)c1-c1ccc(F)cc1
[c] O=C(OC1C[C@@H]2CC3C[C@H](C1)N2CC3=O)c1c[nH]c2ccccc12
[d] CC(C)(C)NC[C@H](O)COc1nsnc1N1CCOCC1
Answer: a, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}