Based on the SMILES O=C1C(=O)c2ccccc2C(O)=C1C1CCC(c2ccc(Cl)cc2)CC1, the molecule is not metabolized by CYP P450 3A4.
Based on the {SMILES__description} {#representation |!}{SMILES#}, the molecule is {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}.