Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] Fc1cccc2c1O[C@H]1CNC[C@@H]1O2
[b] COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
[c] CN1CCCN([C@H](c2ccccc2)c2ccc(Cl)cc2)CC1
[d] CNCCC=C1c2ccccc2CCc2ccccc21
Answer: a, b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}