Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCCSc1ccc2nc(NC(=O)OC)[nH]c2c1
(b) C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
(c) c1ccc2cc(COC3CCNCC3)ccc2c1
(d) CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC
(e) CC1(C)CC(=O)N(CCCCN2CCN(c3ncccn3)CC2)C(=O)C1
Answer: b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}