Task: Please answer the multiple choice question.
Question: Which molecules are a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1[N+](=O)[O-]
b. CN1C(=O)[C@H](O)N=C(c2ccccc2)c2cc(Cl)ccc21
c. Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1Nc1nccc(-c2cccnc2)n1
d. CCOc1cc(N)c(Cl)cc1C(=O)NC[C@@H]1CN(Cc2ccc(F)cc2)CCO1
e. Nc1c2c(nc3ccccc13)CCCC2
Answer: a, b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}