Task: Please answer the multiple choice question.
Question: Which molecules are a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a. O=C1c2ccccc2C(=O)c2ccccc21
b. CN1C(=O)[C@@](C)(C2=CCCCC2)C(=O)N=C1O
c. COC(=O)C1=C(C#N)NC(C)=C(C(=O)OC(C)C)[C@H]1c1cccc([N+](=O)[O-])c1
Answer: c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}