Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccccc1/C=C\C(=O)OC(C)(C)C
(b) Cc1onc(-c2ccccc2)c1-c1ccc(S(N)(=O)=O)cc1
(c) COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
(d) O=C1CN(/N=C\c2ccc(-c3ccc([N+](=O)[O-])cc3)o2)C(=O)N1
Answer: c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}