The molecule with the SMILES O=c1[nH]c2ccccc2n1CCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1 is not a CYP P450 3A4 substrate.
The molecule with the {SMILES__description} {#representation of |!}{SMILES#} is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.