Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC
(b) CCN(CC)C(=O)N[C@H]1C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1
(c) CCN(CC)c1cc(C)nc2ncnn12
(d) COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC
(e) CCN1C(=O)N[C@H](c2ccccc2)C1=O
Answer: c, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}