User: Is the molecule with the SMILES C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 metabolized by CYP P450 3A4?
Assistant: No, it is not a substrate for CYP P450 3A4.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP3A4_Substrate__names__verb}?
Assistant: {CYP3A4_Substrate#No&Yes}, it is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.