Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CC[C@]1(c2ccc(N)cc2)CCC(=O)NC1=O
b. COc1ccccc1OCCNC[C@H](O)COc1cccc2[nH]c3ccccc3c12
c. C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)C3=CC[C@]2(C)[C@H]1C(=O)CN1CCN(c2cc(N3CCCC3)nc(N3CCCC3)n2)CC1
d. Fc1cccc2c1O[C@H]1CNC[C@@H]1O2
e. C[C@H](CS)C(=O)N1CCC[C@H]1C(=O)O
Answer: a, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}