The molecule with the SMILES O=C(CCCN1CCC(O)(c2cccc(C(F)(F)F)c2)CC1)c1ccc(F)cc1 is not a CYP P450 3A4 substrate.
The molecule with the {SMILES__description} {#representation of |!}{SMILES#} is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.