Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP3A4?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a. FC(F)OC(F)(F)[C@@H](F)Cl
b. CNC(=O)c1cccc(NCC(=O)NCCc2ccc(OC)c(OC)c2)c1
c. OCCN1CCN(CCCN2c3ccccc3C=Cc3ccccc32)CC1
Answer: a, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}