Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
(a) CCc1c(C)[nH]c2c1C(=O)[C@@H](CN1CCOCC1)CC2
(b) CCC[C@H]1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1
(c) Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1
(d) CN1CCCN([C@H](c2ccccc2)c2ccc(Cl)cc2)CC1
Answer: a, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}