Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1
b COc1cc([C@@H]2c3cc4c(cc3[C@@H](O[C@@H]3O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]3O)[C@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1O
c CN1C(=O)CN=C(c2ccccc2)c2cc(Cl)ccc21
d CN(C)c1ccc([C@H]2C[C@@]3(C)[C@@H](CC[C@@]3(O)/C=C/CO)[C@@H]3CCC4=CC(=O)CCC4=C32)cc1
Answer: a
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}