Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. Cc1cccc(Nc2ccccc2C(=O)O)c1C
b. CCCO
c. COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC
d. Cc1[nH]cnc1CN1CCc2c(c3ccccc3n2C)C1=O
Answer: a, b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}