Task: Please answer the multiple choice question.
Question: Which molecules are a CYP3A4 substrate?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a COc1cc2c(cc1OC)C(=O)[C@H](CC1CCN(Cc3ccccc3)CC1)C2
b Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1
c CCOCCn1c(N2CCCN(C)CC2)nc2ccccc21
Answer: a, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}