Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccccc1/C=C\C(=O)OC(C)(C)C
(b) CN(C)CCC=C1c2ccccc2C=Cc2ccccc21
(c) CCCN[C@H]1CCc2nc(N)sc2C1
(d) N[C@@H]1C[C@H]1c1ccccc1
(e) CC(C)(C)NC[C@H](O)COc1nsnc1N1CCOCC1
Answer: c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}