User: Is the molecule with the SMILES COCc1c(C(C)C)nc(C(C)C)c(/C=C\[C@@H](O)C[C@@H](O)CC(=O)O)c1-c1ccc(F)cc1 metabolized by CYP3A4?
Assistant: Yes, it is a substrate for CYP3A4.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP3A4_Substrate__names__verb}?
Assistant: {CYP3A4_Substrate#No&Yes}, it is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.