Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP3A4?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a. CCOC(=O)C1(c2ccccc2)CCN(C)CC1
b. CCn1cc(C(=O)O)c(=O)c2cnc(N3CCNCC3)nc21
c. O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
Answer: a, b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}