Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP3A4 substrate?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a) OC(O)C(Cl)(Cl)Cl
b) O=C1c2ccccc2C(=O)c2ccccc21
c) CCN(CC)C(=O)[C@]1(c2ccccc2)C[C@@H]1CN
Answer: a, b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}