The molecule with the SMILES O=C(O)c1ccccc1Nc1cccc(C(F)(F)F)c1 is not a substrate for CYP P450 3A4.
The molecule with the {SMILES__description} {#representation of |!}{SMILES#} is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.