Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a CCn1cc(C(=O)O)c(=O)c2cnc(N3CCNCC3)nc21
b CC[C@@H]1C(=O)OC[C@@H]1Cc1cncn1C
c Cc1ccnc(NS(=O)(=O)c2ccc(N)cc2)n1
d CN1C(=O)[C@H](O)N=C(c2ccccc2)c2cc(Cl)ccc21
Answer: a, b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}