The molecule with the SMILES COc1cc(Br)c2oc(C3CCNCC3)cc2c1 is not a CYP P450 3A4 substrate.
The molecule with the {SMILES__description} {#representation of |!}{SMILES#} is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.