Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a.) CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O
b.) C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23
c.) O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O
Answer: b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}