Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@@]4(C)CC[C@@H]1[C@]32OO4
[b] NNc1nncc2ccccc12
[c] O=C1CN=C(c2ccccc2)c2cc(Cl)ccc2N1
[d] CN(C)CCc1c[nH]c2ccc(C[C@H]3COC(=O)N3)cc12
Answer: b, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}