Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CCS(=O)(=O)CCn1c([N+](=O)[O-])cnc1C
b.) CCN(CC)c1cc(C)nc2ncnn12
c.) Cc1oncc1C(=O)Nc1ccc(C(F)(F)F)cc1
d.) COCc1c(C(=O)OC(C)C)ncc2[nH]c3ccc(OCc4ccccc4)cc3c12
e.) CCCCC1C(=O)N(c2ccccc2)N(c2ccccc2)C1=O
Answer: b, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}