Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: O=c1c(O)c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c12
b: COC(=O)C1=C(C)NC(C)=C(C(=O)OCC(C)=O)[C@@H]1c1ccccc1[N+](=O)[O-]
c: O=c1[nH]cc(F)c(=O)[nH]1
d: CC[C@H]1CN2CC[C@H]1C[C@@H]2[C@@H](O)c1ccnc2ccc(OC)cc12
e: Nc1nc2ccc(OC(F)(F)F)cc2s1
Answer: b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}