Task: Please answer the multiple choice question.
Question: Which molecules are a CYP3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc([C@H](CN(C)C)C2(O)CCCCC2)cc1
(b) COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)[C@@H](C2)N(C)CC[C@]314
(c) COc1cc([C@@H]2c3cc4c(cc3[C@@H](O[C@@H]3O[C@@H]5CO[C@@H](c6cccs6)O[C@H]5[C@H](O)[C@H]3O)[C@H]3COC(=O)[C@H]23)OCO4)cc(OC)c1O
(d) COC(=O)C1=C(C)NC(C)=C(C(=O)OCC(C)=O)[C@@H]1c1ccccc1[N+](=O)[O-]
(e) N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)cc2)cc1
Answer: a, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}