Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
[a] CN1C(=O)[C@H](O)N=C(c2ccccc2)c2cc(Cl)ccc21
[b] C[C@H](Cn1cnc2c(N)ncnc21)OCP(=O)(O)O
[c] CC[C@H](c1ccccc1)c1c(O)c2ccccc2oc1=O
Answer: b, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}