Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP3A4?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a. CC(C)NC[C@H](O)COc1cccc2[nH]ccc12
b. CCCCN(CCCC)C[C@@H](O)c1cc(Cl)cc2c1-c1ccc(Cl)cc1/C2=C\c1ccc(Cl)cc1
c. FC(F)O[C@@H](Cl)C(F)(F)F
Answer: a, c
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}