Task: Please answer the multiple choice question.
Question: Which molecules are a CYP3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CCCCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21
[b] CC(C)(C)N1CCC(c2ccccc2)(c2ccccc2)CC1
[c] FC(F)O[C@@H](Cl)C(F)(F)F
[d] COc1ccc(-c2nc3cc(C4=NNC(=O)C[C@H]4C)ccc3[nH]2)cc1
[e] CC/C(=C(\CC)c1ccc(O)cc1)c1ccc(O)cc1
Answer: a, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}