Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -5.185% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Nc1ccc(S(=O)(=O)Nc2nccc(/C=C/c3ccccc3F)n2)cc1
b) O=C(Nc1nc2ccc([N+](=O)[O-])cc2s1)c1c(F)cccc1F
c) CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1
d) CC(C)N1CCc2c(sc(NC(=O)c3nc4ccccc4s3)c2C(N)=O)C1.Cl
e) CC1Cc2ccccc2N1C(=O)C1CCCN(S(=O)(=O)c2cccc3cccnc23)C1
Answer: c. CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1
CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1
ethyl 4-(3,4-dimethylphenyl)sulfonylpiperazine-1-carboxylate