Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -21.875% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1cc(NC(=O)CN(c2cc(C)cc(C)c2)S(=O)(=O)c2c(C)noc2C)cc(OC)c1
b CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)Nc2ccc(C)cc2[N+](=O)[O-])c1C
c COc1ccc(-n2cnc3c(sc4nc(N5CCOCC5)c5c(c43)CCCC5)c2=O)cc1
d O=C(N1CCCCC1)N1CCN(c2ccc(Cl)cc2)CC1
e CCOC(=O)c1c(C)[nH]c(=S)c(C#N)c1-c1ccccc1
Answer: d. O=C(N1CCCCC1)N1CCN(c2ccc(Cl)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(N1CCCCC1)N1CCN(c2ccc(Cl)cc2)CC1
O=C(N1CCCCC1)N1CCN(c2ccc(Cl)cc2)CC1
4-(4-chlorophenyl)-1-(piperidine-1-carbonyl)piperazine