Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -22.682% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1cccc(NC(=O)Cn2cnc3sc(C)c(S(=O)(=O)N4CCC(C)CC4)c3c2=O)n1
b. O=c1c(-c2nnc(SCc3ccc(Cl)c(Cl)c3)o2)cccn1Cc1ccccc1
c. CCN(CC)C(=S)SCCC(=O)NC(=O)Oc1ccc(C)cc1
d. COc1ccc(Nc2nc(N3CCN(S(C)(=O)=O)CC3)nc3ccccc23)c(OC)c1
e. O=C(Nc1ccc2c(c1)C(=O)N(CC1CCCO1)C2=O)c1ccccc1Br
Answer: d. COc1ccc(Nc2nc(N3CCN(S(C)(=O)=O)CC3)nc3ccccc23)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(Nc2nc(N3CCN(S(C)(=O)=O)CC3)nc3ccccc23)c(OC)c1
COc1ccc(Nc2nc(N3CCN(S(C)(=O)=O)CC3)nc3ccccc23)c(OC)c1
N-(2,4-dimethoxyphenyl)-2-(4-methylsulfonylpiperazin-1-yl)quinazolin-4-amine