Problem statement: Answer the MCQ question.
Question: Which drug has a -16.328% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] CN(C(=O)CSc1nnc(NC2CCCCC2)s1)C1CCS(=O)(=O)C1
[b] Cc1ccccc1N(C(=O)Cc1cccs1)C(C(=O)NCC1CCCO1)c1cccnc1
[c] COc1ccc(C(=O)NCC(=O)OCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1
[d] CCCCCN(CCCCC)C(=O)C(CCC(=O)[O-])NC(=O)c1ccc(Cl)c(Cl)c1.[Na+]
Answer: b. Cc1ccccc1N(C(=O)Cc1cccs1)C(C(=O)NCC1CCCO1)c1cccnc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccccc1N(C(=O)Cc1cccs1)C(C(=O)NCC1CCCO1)c1cccnc1
Cc1ccccc1N(C(=O)Cc1cccs1)C(C(=O)NCC1CCCO1)c1cccnc1
2-(2-methyl-N-(2-thiophen-2-ylacetyl)anilino)-N-(oxolan-2-ylmethyl)-2-pyridin-3-ylacetamide