Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -1.878% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(CCN1C(=O)/C(=C/c2ccc(Cl)cc2)SC1=S)NC1C=CS(=O)(=O)C1
b. COc1cc2c(cc1OC)-c1cc(NC3CCCC3)nc(=O)n1CC2
c. CCN(CC)S(=O)(=O)c1cc(C)c(C)cc1Br
d. COc1ccc(C2=NN3C(C2)c2ccccc2OC32C(=O)N(C)c3ccccc32)cc1
e. CC(=O)Nc1cccc2ncccc12
Answer: d. COc1ccc(C2=NN3C(C2)c2ccccc2OC32C(=O)N(C)c3ccccc32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2=NN3C(C2)c2ccccc2OC32C(=O)N(C)c3ccccc32)cc1
COc1ccc(C2=NN3C(C2)c2ccccc2OC32C(=O)N(C)c3ccccc32)cc1
2-(4-methoxyphenyl)-1'-methylspiro[1,10b-dihydropyrazolo[1,5-c][1,3]benzoxazine-5,3'-indole]-2'-one