Task: Answer the MCQ question.
Question: Which compound has a -13.533% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1ccc(NC(=O)C2CCN(S(=O)(=O)c3c(C)n[nH]c3C)CC2)nc1
b) CCOC(=O)c1sc2nc(SCC#N)n(CC3CCCO3)c(=O)c2c1C
c) Cc1nn(-c2ccccc2)c2c1C(c1ccc(F)cc1)C(C#N)=C(N)O2
d) Cc1sc2ncn3ncnc3c2c1C
e) CCc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)N3CCCC3)cc2)c(Br)c1
Answer: b. CCOC(=O)c1sc2nc(SCC#N)n(CC3CCCO3)c(=O)c2c1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1sc2nc(SCC#N)n(CC3CCCO3)c(=O)c2c1C
CCOC(=O)c1sc2nc(SCC#N)n(CC3CCCO3)c(=O)c2c1C
ethyl 2-(cyanomethylsulfanyl)-5-methyl-4-oxo-3-(oxolan-2-ylmethyl)thieno[2,3-d]pyrimidine-6-carboxylate