Task: Answer the multiple choice question.
Question: Which drug has a -27.966% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C(CN1C(=O)CCS(=O)(=O)c2ccccc21)NCc1ccc(F)cc1
b COc1cccc(NC(=O)N2CCCC(C(=O)Nc3ccccc3OC)C2)c1
c C=C[C@@](C)(O)CC[C@@H]1[C@@]2(C)CCCC(C)(C)[C@@H]2CC[C@@]1(C)O
d CSC1=NSC2=NC(=O)/C(=C/c3coc4ccc(O)cc4c3=O)C(=N)N12
e CCN(CC)C(=O)c1ccc(NC(=O)COc2ccc([N+](=O)[O-])cc2Cl)cc1
Answer: b. COc1cccc(NC(=O)N2CCCC(C(=O)Nc3ccccc3OC)C2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(NC(=O)N2CCCC(C(=O)Nc3ccccc3OC)C2)c1
COc1cccc(NC(=O)N2CCCC(C(=O)Nc3ccccc3OC)C2)c1
3-N-(2-methoxyphenyl)-1-N-(3-methoxyphenyl)piperidine-1,3-dicarboxamide