Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -2.268% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(-c2cc(C(F)(F)F)nc(N3CCCCC3)n2)cc1OC
b) COc1cccc(C(=O)NCc2nnc(SCC(=O)Nc3nccs3)n2-c2cccc(C)c2)c1
c) CC(C)(C)OC(=O)N(Cc1ccccc1)S(C)(=O)=O
d) COc1ccc(C(=O)C2CCCN(C(=O)C3=CCCC3)C2)c(C)c1
e) Cc1ccc(NC(=O)c2ccc(-c3nn(C)c(=O)c4ccccc34)cc2)c(C)c1
Answer: d. COc1ccc(C(=O)C2CCCN(C(=O)C3=CCCC3)C2)c(C)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)C2CCCN(C(=O)C3=CCCC3)C2)c(C)c1
COc1ccc(C(=O)C2CCCN(C(=O)C3=CCCC3)C2)c(C)c1
[1-(cyclopentene-1-carbonyl)piperidin-3-yl]-(4-methoxy-2-methylphenyl)methanone