Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -36.019% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. O=c1ccc2cc3c([nH]c4ccc(Br)cc43)oc-2c1O
b. Cc1ccccc1NC(=O)CSCCO
c. CC1CCN(C(=O)COc2cccc3c2CCN(Cc2ccccc2)C3=O)CC1
d. CC(C)CCOc1cccc(OCC(=O)NC2CCS(=O)(=O)C2)c1
e. Cc1c(/C=N/O)sc2ccccc12
Answer: c. CC1CCN(C(=O)COc2cccc3c2CCN(Cc2ccccc2)C3=O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1CCN(C(=O)COc2cccc3c2CCN(Cc2ccccc2)C3=O)CC1
CC1CCN(C(=O)COc2cccc3c2CCN(Cc2ccccc2)C3=O)CC1
2-benzyl-5-[2-(4-methylpiperidin-1-yl)-2-oxoethoxy]-3,4-dihydroisoquinolin-1-one