Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -26.774% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. COC(=O)c1ccc(-c2ccco2)n1Cc1nc(-c2ccc(OC)c(OC)c2)oc1C
b. CCC(=O)c1ccc(N2CCN(C(=O)c3ccccc3Br)CC2)c(F)c1
c. CCSc1nc2c(c(=O)n1Cc1ccccc1)SC(C)C2
d. CCN(CC)C(=O)COc1ccc(-c2nnc(Nc3ccc(OC)c(C(=O)NC)c3)c3ccccc23)cc1
Answer: b. CCC(=O)c1ccc(N2CCN(C(=O)c3ccccc3Br)CC2)c(F)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC(=O)c1ccc(N2CCN(C(=O)c3ccccc3Br)CC2)c(F)c1
CCC(=O)c1ccc(N2CCN(C(=O)c3ccccc3Br)CC2)c(F)c1
1-[4-[4-(2-bromobenzoyl)piperazin-1-yl]-3-fluorophenyl]propan-1-one