Problem statement: Answer the multiple choice question.
Question: Which drug has a -15.741% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCOC(=O)N1CCN(CCC(=O)Nc2ccc(Br)cc2)CC1
b) COc1ccc(CNC(=O)C(c2ccncc2)N(C(=O)Cc2cccs2)c2ccc(C)cc2)cc1
c) COC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccncc3)n2C)cc1
d) O=C(OCC(=O)N1CCN(c2ccccc2)CC1)C1=COCCO1
e) COc1ccc(N(CC(=O)Nc2ccc3c(c2)OCO3)S(=O)(=O)c2c(C)nn(C)c2C)cc1
Answer: b. COc1ccc(CNC(=O)C(c2ccncc2)N(C(=O)Cc2cccs2)c2ccc(C)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C(c2ccncc2)N(C(=O)Cc2cccs2)c2ccc(C)cc2)cc1
COc1ccc(CNC(=O)C(c2ccncc2)N(C(=O)Cc2cccs2)c2ccc(C)cc2)cc1
N-[(4-methoxyphenyl)methyl]-2-(4-methyl-N-(2-thiophen-2-ylacetyl)anilino)-2-pyridin-4-ylacetamide