Problem statement: Answer the MCQ question.
Query: Which compound has a -18.894% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a.) CC(C)c1nnc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(Cl)cc2)s1
b.) CCN(CC)CCNc1nc(C(F)(F)F)nc2c1nnn2Cc1ccccc1
c.) Cc1ccc(C)c(N2CCN(C(=O)CCC(=O)N3CCOc4ccc(Cl)cc43)CC2)c1
d.) O=C(Cc1c[nH]c2ccccc12)NCc1cccs1
Answer: c. Cc1ccc(C)c(N2CCN(C(=O)CCC(=O)N3CCOc4ccc(Cl)cc43)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(C)c(N2CCN(C(=O)CCC(=O)N3CCOc4ccc(Cl)cc43)CC2)c1
Cc1ccc(C)c(N2CCN(C(=O)CCC(=O)N3CCOc4ccc(Cl)cc43)CC2)c1
1-(6-chloro-2,3-dihydro-1,4-benzoxazin-4-yl)-4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butane-1,4-dione