Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -1.442% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a CC1(C)CC(=O)C(Sc2nnc(-c3ccc(NS(C)(=O)=O)cc3)n2Cc2ccco2)C(=O)C1
b Cc1cc2c(c(=O)n1Cc1cccnc1)C(Cc1ccccc1)C(C#N)=C(N)O2
c N#CC1=C(N)OC2=C(CN(Cc3ccccc3)C/C2=C\c2cccnc2)C1c1cccnc1
d CC(C)NC(=O)CSCc1cccc(Br)c1
Answer: c. N#CC1=C(N)OC2=C(CN(Cc3ccccc3)C/C2=C\c2cccnc2)C1c1cccnc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#CC1=C(N)OC2=C(CN(Cc3ccccc3)C/C2=C\c2cccnc2)C1c1cccnc1
N#CC1=C(N)OC2=C(CN(Cc3ccccc3)C/C2=C\c2cccnc2)C1c1cccnc1
(8E)-2-amino-6-benzyl-4-pyridin-3-yl-8-(pyridin-3-ylmethylidene)-5,7-dihydro-4H-pyrano[3,2-c]pyridine-3-carbonitrile