Problem statement: Answer the multiple choice question.
Question: Which compound exhibits a -5.135% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. Cc1nc2ccccn2c1-c1nnco1
b. COC(=O)CNC(=O)CNC(=O)Nc1ccccc1Cl
c. COc1cccc(NC(=S)N/N=C\c2cn(C)c3ccc(S(=O)(=O)N4CCOCC4)cc23)c1
d. COP(=O)(OC)/C(C=O)=N/Nc1ccc([N+](=O)[O-])cc1
e. COC(=O)c1cccc(CSc2nc3ccccc3[nH]2)c1
Answer: c. COc1cccc(NC(=S)N/N=C\c2cn(C)c3ccc(S(=O)(=O)N4CCOCC4)cc23)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(NC(=S)N/N=C\c2cn(C)c3ccc(S(=O)(=O)N4CCOCC4)cc23)c1
COc1cccc(NC(=S)N/N=C\c2cn(C)c3ccc(S(=O)(=O)N4CCOCC4)cc23)c1
1-[(Z)-(1-methyl-5-morpholin-4-ylsulfonylindol-3-yl)methylideneamino]-3-(5-methoxyphenyl)thiourea