Problem statement: Answer the MCQ question.
Question: Which compound exhibits a -7.399% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C(CSc1ccc([N+](=O)[O-])cn1)Nc1cc(C(F)(F)F)ccc1N1CCOCC1
(b) CCc1cc(SC#N)cc(C)c1N
(c) COc1ccc(/C=N/NC(=S)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2N2CCOCC2)cc1O
(d) NC(=O)CN1CCN(C(=O)Nc2ccccc2)CC1
(e) O=C(COc1ccccc1)N(Cc1ccco1)C1CCS(=O)(=O)C1
Answer: c. COc1ccc(/C=N/NC(=S)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2N2CCOCC2)cc1O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(/C=N/NC(=S)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2N2CCOCC2)cc1O
COc1ccc(/C=N/NC(=S)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2N2CCOCC2)cc1O
1-(2-morpholin-4-yl-5-morpholin-4-ylsulfonylphenyl)-3-[(E)-(5-hydroxy-4-methoxyphenyl)methylideneamino]thiourea