Problem statement: Answer the multiple choice question.
Query: Which compound has a -8.148% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C(C1=C[C@@H](c2coc3ccccc3c2=O)C[C@@H](OCCCCO)O1)N1CCN(Cc2ccccc2)CC1
b) O=C(Nc1ccc(N2CCN(C(=O)c3ccco3)CC2)cc1)c1cccs1
c) Cc1cccc(C(=O)Nc2ccc(C(=O)N/N=C/c3ccco3)cc2)c1
d) COc1cc2c(=O)n(CCC(=O)NCC3CCCO3)c(=O)n(CC(=O)Nc3ccc(C)c(C)c3)c2cc1OC
e) CCOC(=O)N1CCN(c2c(NCCCN(CC)CC)c(=O)c2=O)CC1
Answer: b. O=C(Nc1ccc(N2CCN(C(=O)c3ccco3)CC2)cc1)c1cccs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1ccc(N2CCN(C(=O)c3ccco3)CC2)cc1)c1cccs1
O=C(Nc1ccc(N2CCN(C(=O)c3ccco3)CC2)cc1)c1cccs1
N-[4-[4-(furan-2-carbonyl)piperazin-1-yl]phenyl]thiophene-2-carboxamide