Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -16.491% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) COc1cc(-n2nc(C)c3c2OC(N)=C(C#N)C3c2ccccc2)c(Cl)c(Br)c1O
(b) Cc1ccc(N(CC(=O)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)S(C)(=O)=O)cc1C
(c) O=C1C=C(NCc2ccc(Cl)cc2Cl)C2(CCCCC2)O1
(d) CCOC(=O)CC1(C)OCC(C[N+]2(C)CCCCC2)O1.[I-]
Answer: d. CCOC(=O)CC1(C)OCC(C[N+]2(C)CCCCC2)O1.[I-]
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)CC1(C)OCC(C[N+]2(C)CCCCC2)O1.[I-]
CCOC(=O)CC1(C)OCC(C[N+]2(C)CCCCC2)O1.[I-]
ethyl 2-[2-methyl-4-[(1-methylpiperidin-1-ium-1-yl)methyl]-1,3-dioxolan-2-yl]acetate;iodide