Task: Answer the MCQ question.
Query: Which drug exhibits a -42.281% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a N#Cc1cn(CC(=O)N2CCc3ccccc3C2)c2ccccc12
b CCOCCCNC(=O)c1ccc(OC)cc1
c COc1ccc(N2CCN(C(=O)CCCN3C(=O)c4cccc5cccc(c45)C3=O)CC2)cc1
d COc1cccc(CNC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCCC4)cc32)c1
Answer: d. COc1cccc(CNC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCCC4)cc32)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCCC4)cc32)c1
COc1cccc(CNC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCCC4)cc32)c1
N-[(5-methoxyphenyl)methyl]-2-(3-oxo-6-pyrrolidin-1-ylsulfonyl-1,4-benzothiazin-4-yl)acetamide