Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -44.531% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cc1c(O)cccc1C(=O)N[C@@H](CSc1ccccc1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C
b Cc1cc(C)nc(Nc2ccc(N3CCOCC3)cc2)n1
c C=CCn1c(Cc2cccs2)nnc1SCC(=O)Nc1cc(OC)cc(OC)c1
d CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(SC)cc3)cc2)CC1
e O=C(CCc1nnc(-c2ccsc2)o1)NCc1ccccc1OC(F)(F)F
Answer: d. CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(SC)cc3)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(SC)cc3)cc2)CC1
CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(SC)cc3)cc2)CC1
1-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-3-(4-methylsulfanylphenyl)urea