Task: Answer the multiple-choice question.
Question: Which compound has a -74.270% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1cccc(-c2ccc(NC(=O)C3CCCN(Cc4cnc(C)n4C)C3)cc2)c1
(b) Cc1c(C(O)CN2CCN(Cc3ccc4c(c3)OCO4)CC2)c2ccccc2n1C
(c) CCOc1cccc(-c2nnc3n2N=C(c2cc(OC)ccc2OC)CS3)c1
(d) COc1ccc(/C=C/C(=O)Nc2ccc(N3CCOCC3)cc2)cc1
(e) CC(C)CNS(=O)(=O)c1ccc(CCC(=O)N2CCN(Cc3ccc4c(c3)OCO4)CC2)cc1
Answer: a. COc1cccc(-c2ccc(NC(=O)C3CCCN(Cc4cnc(C)n4C)C3)cc2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(-c2ccc(NC(=O)C3CCCN(Cc4cnc(C)n4C)C3)cc2)c1
COc1cccc(-c2ccc(NC(=O)C3CCCN(Cc4cnc(C)n4C)C3)cc2)c1
1-[(2,3-dimethylimidazol-4-yl)methyl]-N-[4-(3-methoxyphenyl)phenyl]piperidine-3-carboxamide