Problem statement: Answer the multiple choice question.
Query: Which drug has a -30.146% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(Nc1nnc(C(F)(F)F)s1)c1c(F)cccc1F
b.) Nn1c(SCc2cn3ccsc3n2)nnc1-c1ccncc1
c.) CCCC(C)c1nnc(NC(=O)C2CC(=O)N(CCc3ccc(F)cc3)C2)s1
d.) COc1ccc(CC(NC(C)=O)C(=O)NC2CCN(C(=O)NCc3ccccc3)CC2)cc1
e.) FC(F)(F)c1ccc(C2[C@H]3CN(Cc4ccc(-c5ccccc5)cc4)[C@H](c4ccccc4)C34CC2(c2ccccc2)C4)cc1
Answer: c. CCCC(C)c1nnc(NC(=O)C2CC(=O)N(CCc3ccc(F)cc3)C2)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCC(C)c1nnc(NC(=O)C2CC(=O)N(CCc3ccc(F)cc3)C2)s1
CCCC(C)c1nnc(NC(=O)C2CC(=O)N(CCc3ccc(F)cc3)C2)s1
1-[2-(4-fluorophenyl)ethyl]-5-oxo-N-(5-pentan-2-yl-1,3,4-thiadiazol-2-yl)pyrrolidine-3-carboxamide