Problem statement: Answer the MCQ question.
Query: Which drug has a -5.411% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: CCC(C)(C)NC(=O)C(C(C)C)N(CC1CCCO1)C(=O)CNS(=O)(=O)c1ccc(F)cc1
b: CC(=O)Nc1ccc(Oc2nc(-c3ccccn3)nc3ccccc23)cc1
c: O=C(c1sc(N2CCOCC2)nc1-c1ccccc1)N1CCCCC1
d: COc1ccc(S(=O)(=O)N2CCC(C(=O)NCCc3c[nH]c4ccccc34)CC2)cc1
Answer: a. CCC(C)(C)NC(=O)C(C(C)C)N(CC1CCCO1)C(=O)CNS(=O)(=O)c1ccc(F)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC(C)(C)NC(=O)C(C(C)C)N(CC1CCCO1)C(=O)CNS(=O)(=O)c1ccc(F)cc1
CCC(C)(C)NC(=O)C(C(C)C)N(CC1CCCO1)C(=O)CNS(=O)(=O)c1ccc(F)cc1
2-[[2-[(4-fluorophenyl)sulfonylamino]acetyl]-(oxolan-2-ylmethyl)amino]-3-methyl-N-(2-methylbutan-2-yl)butanamide