Problem statement: Answer the MCQ question.
Query: Which compound has a -39.625% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccc2c(c1)C(=O)[C@H](O)[C@@H](c1ccc(OC)c(Br)c1)O2
b. COc1ccc(CCNS(=O)(=O)c2ccc(-n3cnnn3)c(OC)c2)cc1OC
c. COc1ccc(N(C(=O)c2cccnc2)S(=O)(=O)c2ccccc2)cc1
d. CN(C(=O)COC(=O)c1ccc(S(=O)(=O)N2CCOCC2)cc1)C1CCCCC1
e. Cc1ccc(-c2nn(CCC(N)=O)c(=O)c3ccccc23)cc1
Answer: c. COc1ccc(N(C(=O)c2cccnc2)S(=O)(=O)c2ccccc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N(C(=O)c2cccnc2)S(=O)(=O)c2ccccc2)cc1
COc1ccc(N(C(=O)c2cccnc2)S(=O)(=O)c2ccccc2)cc1
N-(benzenesulfonyl)-N-(4-methoxyphenyl)pyridine-3-carboxamide