Task: Answer the MCQ question.
Question: Which compound has a -1.803% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(NC(=O)CN(c2ccccc2)S(=O)(=O)N(C)C)cc1Cl
(b) CCCCN(C)CCNC(=O)c1c[nH]c2ccc(S(=O)(=O)N(CC)CC)cc2c1=O
(c) CCOC(=O)N1CCN(C(=O)C2CCC(=O)N(CCc3ccccc3)C2)CC1
(d) CCCCN(C(=O)CSc1nnnn1C)C1CCS(=O)(=O)C1
(e) Brc1c(CSc2nncc3ccccc23)nc2ccccn12
Answer: b. CCCCN(C)CCNC(=O)c1c[nH]c2ccc(S(=O)(=O)N(CC)CC)cc2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCN(C)CCNC(=O)c1c[nH]c2ccc(S(=O)(=O)N(CC)CC)cc2c1=O
CCCCN(C)CCNC(=O)c1c[nH]c2ccc(S(=O)(=O)N(CC)CC)cc2c1=O
N-[2-[butyl(methyl)amino]ethyl]-6-(diethylsulfamoyl)-4-oxo-1H-quinoline-3-carboxamide