Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 8.116% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCCCn1c(SCC(=O)NCc2ccco2)nc2c(sc3ccccc32)c1=O
b.) COc1ccc(CNC(=O)C2CCCN(S(=O)(=O)c3c(C)nn(C)c3C)C2)cc1
c.) COc1ccc(C(=O)OCCOc2cccc(Cl)c2)cc1S(=O)(=O)N1CCOCC1
d.) COc1ccc(S(=O)(=O)NCC(c2cccnc2)N2CCN(C)CC2)cc1OC
e.) COc1cc(-c2onc3ccc(Br)cc23)cc(OC)c1OC
Answer: b. COc1ccc(CNC(=O)C2CCCN(S(=O)(=O)c3c(C)nn(C)c3C)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C2CCCN(S(=O)(=O)c3c(C)nn(C)c3C)C2)cc1
COc1ccc(CNC(=O)C2CCCN(S(=O)(=O)c3c(C)nn(C)c3C)C2)cc1
N-[(4-methoxyphenyl)methyl]-1-(1,3,5-trimethylpyrazol-4-yl)sulfonylpiperidine-3-carboxamide