Task: Answer the MCQ question.
Query: Which drug has a -19.312% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] c1ccc(C2=Nn3c(nnc3-c3ccncc3)SC2)cc1
[b] CC1=NN(C(=O)Cc2ccccc2)C(O)(c2cccnc2)C1
[c] COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc(Cl)c(S(=O)(=O)N(C)C)c1)CC2
[d] COc1ccc(OCCNC(=O)c2ccccc2OCC(=O)N2CCCCC2)cc1
[e] CCN(CC)S(=O)(=O)c1ccc(/C=C/C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1
Answer: c. COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc(Cl)c(S(=O)(=O)N(C)C)c1)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc(Cl)c(S(=O)(=O)N(C)C)c1)CC2
COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc(Cl)c(S(=O)(=O)N(C)C)c1)CC2
N-[4-chloro-3-(dimethylsulfamoyl)phenyl]-2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)acetamide