Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 4.504% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccc(NC(=S)NCCN2CCOCC2)cc1
b: CC(=O)OC1OCCOC1NC(=S)NCc1ccco1
c: CCOc1ccc(NC(=O)CC2C(=O)N(C)C(=S)N2Cc2ccco2)cc1
d: CCN(CC)CCNC(=O)c1ccccn1.O=C([O-])/C=C\C(=O)[O-]
e: COc1ccc([C@H](OC)[C@@]2(Cc3ccc(O)cc3)N=C(N)N(C)C2=O)cc1
Answer: e. COc1ccc([C@H](OC)[C@@]2(Cc3ccc(O)cc3)N=C(N)N(C)C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@H](OC)[C@@]2(Cc3ccc(O)cc3)N=C(N)N(C)C2=O)cc1
COc1ccc([C@H](OC)[C@@]2(Cc3ccc(O)cc3)N=C(N)N(C)C2=O)cc1
(5R)-2-amino-5-[(4-hydroxyphenyl)methyl]-5-[(S)-methoxy-(4-methoxyphenyl)methyl]-3-methylimidazol-4-one