Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -8.902% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COCCn1c(SCC(=O)Nc2ccc(F)cc2F)nc2c([nH]c3ccccc32)c1=O
b: CCOC(=O)c1ccc(N2C(=O)C3CCCN3C2=S)cc1
c: COc1cccc(CNc2nc3ccccc3n2CCN2CCCCC2)c1
d: CCOC(=O)[C@H]1[C@H]2COc3ccc(OC)cc3[C@@H]2N2C(=O)c3ccc(C)cc3NC(=O)[C@@]12C
e: CC(c1nc2ccccc2c(=O)[nH]1)N(C)c1ccc2ccccc2c1
Answer: d. CCOC(=O)[C@H]1[C@H]2COc3ccc(OC)cc3[C@@H]2N2C(=O)c3ccc(C)cc3NC(=O)[C@@]12C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)[C@H]1[C@H]2COc3ccc(OC)cc3[C@@H]2N2C(=O)c3ccc(C)cc3NC(=O)[C@@]12C
CCOC(=O)[C@H]1[C@H]2COc3ccc(OC)cc3[C@@H]2N2C(=O)c3ccc(C)cc3NC(=O)[C@@]12C
ethyl(2R,11R,12S,13R)-5-methoxy-13,18-dimethyl-14,22-dioxo-9-oxa-1,15-diazapentacyclo[11.9.0.02,11.03,8.016,21]docosa-3(8),4,6,16(21),17,19-hexaene-12-carboxylate