Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -47.386% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(N/N=C/c1cccc(O)c1)c1ccc(NC(=O)c2cccc([N+](=O)[O-])c2)cc1
b.) CCOC(=O)c1cc[nH]c1C
c.) CCc1nnc(NC(=O)CSc2nc3c(c(=O)n2-c2ccccc2OC)SCC3)s1
d.) Cc1ccccc1C(=O)NC1CCN(CC(=O)NC2CCCCC2)CC1
e.) COc1ccc(NC(=O)CN(C)C(=O)c2ccccc2OCC(=O)Nc2cccc(C(F)(F)F)c2)cc1
Answer: e. COc1ccc(NC(=O)CN(C)C(=O)c2ccccc2OCC(=O)Nc2cccc(C(F)(F)F)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)CN(C)C(=O)c2ccccc2OCC(=O)Nc2cccc(C(F)(F)F)c2)cc1
COc1ccc(NC(=O)CN(C)C(=O)c2ccccc2OCC(=O)Nc2cccc(C(F)(F)F)c2)cc1
N-[2-(4-methoxyanilino)-2-oxoethyl]-N-methyl-2-[2-oxo-2-[3-(trifluoromethyl)anilino]ethoxy]benzamide