Task: Answer the multiple choice question.
Question: Which drug exhibits a 3.339% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1ccc(-c2cc(C(=O)NCc3cccs3)no2)cc1
(b) O=C(Cn1ccccc1=O)Nc1ccc(Cl)c(S(=O)(=O)N2CCCCC2)c1
(c) CC(C)CNC(=O)C1Nc2ccc(C(F)(F)F)cc2C2C=CCC12
(d) Cl.OC(COc1ccccc1)CN1C2=NCCCN2c2ccccc21
(e) COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(C3CC3)N(c3cccc(C#N)c3)C=C2C1=O
Answer: e. COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(C3CC3)N(c3cccc(C#N)c3)C=C2C1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(C3CC3)N(c3cccc(C#N)c3)C=C2C1=O
COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(C3CC3)N(c3cccc(C#N)c3)C=C2C1=O
4-O-[2-(3-cyanophenyl)-3-cyclopropyl-7-methyl-6,8-dioxoisoquinolin-7-yl] 1-O-methyl butanedioate