Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -38.231% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
[a] CCOC(=O)[C@H]1[C@H]2COc3cc(OC)ccc3[C@@H]2N2C(=O)N(c3ccc(Br)cc3)C(=O)[C@@]12C
[b] O=C(CC1Sc2ccccc2NC1=O)NCc1ccc(Cl)cc1
[c] CCOC(=O)C1CCN(C(=O)Nc2ccc(OC(F)(F)F)cc2)CC1
Answer: c. CCOC(=O)C1CCN(C(=O)Nc2ccc(OC(F)(F)F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1CCN(C(=O)Nc2ccc(OC(F)(F)F)cc2)CC1
CCOC(=O)C1CCN(C(=O)Nc2ccc(OC(F)(F)F)cc2)CC1
ethyl1-[[4-(trifluoromethoxy)phenyl]carbamoyl]piperidine-4-carboxylate