Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -3.293% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(S(=O)(=O)N(C)CC(=O)N2CCCCCC2)cc1OC
(b) COc1ccc(CCNC(=O)CN(c2cccc([N+](=O)[O-])c2)S(C)(=O)=O)cc1
(c) O=C(Nc1ccc(N2CCOCC2)cc1)c1ccc([N+](=O)[O-])o1
(d) CCCOc1ccc(C(=O)NCC(C)(C)N2CCOCC2)cc1
(e) O=C1CCCCCN1Cc1nnc(SCc2nc3ccccc3s2)n1-c1ccccn1
Answer: e. O=C1CCCCCN1Cc1nnc(SCc2nc3ccccc3s2)n1-c1ccccn1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1CCCCCN1Cc1nnc(SCc2nc3ccccc3s2)n1-c1ccccn1
O=C1CCCCCN1Cc1nnc(SCc2nc3ccccc3s2)n1-c1ccccn1
1-[[5-(1,3-benzothiazol-2-ylmethylsulfanyl)-4-pyridin-2-yl-1,2,4-triazol-3-yl]methyl]azepan-2-one