Problem statement: Answer the MCQ question.
Question: Which compound exhibits a -10.780% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) COc1ccc(CCNC(=O)CCCn2nc(C)c([N+](=O)[O-])c2C)cc1OC
(b) COc1ccc(CC(=O)OCC(=O)N2CCN(S(=O)(=O)c3ccc(C)cc3C)CC2)cc1
(c) COc1ccc(N2CCN(C(=O)COc3ccc4ccccc4c3)CC2)cc1
(d) COc1ccc(OCc2n[nH]c(=S)n2-c2ccc(C)cc2)cc1
Answer: b. COc1ccc(CC(=O)OCC(=O)N2CCN(S(=O)(=O)c3ccc(C)cc3C)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CC(=O)OCC(=O)N2CCN(S(=O)(=O)c3ccc(C)cc3C)CC2)cc1
COc1ccc(CC(=O)OCC(=O)N2CCN(S(=O)(=O)c3ccc(C)cc3C)CC2)cc1
[2-[4-(2,4-dimethylphenyl)sulfonylpiperazin-1-yl]-2-oxoethyl] 2-(4-methoxyphenyl)acetate