Task: Answer the MCQ question.
Question: Which drug exhibits a -76.178% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CS(=O)(=O)NC1CCN(Cc2ccccc2)CC1
(b) Cc1cccc(NC(=O)NNC(=O)COc2ccc3ccccc3c2)c1
(c) COc1ccc(C(=O)Nc2ccccc2C(=O)NC(C(=O)NCc2ccco2)C(C)C)cc1
(d) CCCN1CCC(=O)N([C@H](CSc2ccc(Br)cc2)c2ccccc2)CC1
(e) O=C(N/N=C/C=C/c1ccccc1)c1ccc(Br)cc1
Answer: d. CCCN1CCC(=O)N([C@H](CSc2ccc(Br)cc2)c2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCN1CCC(=O)N([C@H](CSc2ccc(Br)cc2)c2ccccc2)CC1
CCCN1CCC(=O)N([C@H](CSc2ccc(Br)cc2)c2ccccc2)CC1
4-[(1S)-2-(4-bromophenyl)sulfanyl-1-phenylethyl]-1-propyl-1,4-diazepan-5-one