Problem statement: Answer the MCQ question.
Query: Which compound has a -38.596% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C1[C@H]2CC3CCC2(O3)[C@@H]2OCCCN12
b) COc1ccc(C(CNC(=O)c2cc3ccccc3o2)N2CCCC2)cc1
c) Cc1ccc(S(=O)(=O)N2CCN(Cc3cc(C(C)(C)C)ccc3O)CC2)cc1
d) CC(C)(C)c1cnnn1-c1ccc(/C=N/Nc2ccc([N+](=O)[O-])cc2)cc1
e) CC(=O)c1cccc(NC(=O)c2cc(Cl)sc2Cl)c1
Answer: b. COc1ccc(C(CNC(=O)c2cc3ccccc3o2)N2CCCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(CNC(=O)c2cc3ccccc3o2)N2CCCC2)cc1
COc1ccc(C(CNC(=O)c2cc3ccccc3o2)N2CCCC2)cc1
N-[2-(4-methoxyphenyl)-2-pyrrolidin-1-ylethyl]-1-benzofuran-2-carboxamide