Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 7.999% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1cc(C2/C(=C(\O)c3ccc4c(c3)OCCO4)C(=O)C(=O)N2c2nnc(C)s2)cc(OC)c1OC
[b] Cc1ccc(-n2ccnc2SCC(=O)O)c(C)c1
[c] COc1ccc(CN2CCNC(=O)C2CC(=O)N(C)CCC2CCOCC2)c(OC)c1
[d] CCN1CCN(c2nc(Nc3ccc(C)c(C)c3)nc(N)c2[N+](=O)[O-])CC1
[e] CC(=O)C1=C(O)C(=O)N(CCc2c[nH]c3ccccc23)C1c1ccccc1
Answer: c. COc1ccc(CN2CCNC(=O)C2CC(=O)N(C)CCC2CCOCC2)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CN2CCNC(=O)C2CC(=O)N(C)CCC2CCOCC2)c(OC)c1
COc1ccc(CN2CCNC(=O)C2CC(=O)N(C)CCC2CCOCC2)c(OC)c1
2-[1-[(2,4-dimethoxyphenyl)methyl]-3-oxopiperazin-2-yl]-N-methyl-N-[2-(oxan-4-yl)ethyl]acetamide