Problem statement: Answer the MCQ question.
Question: Which drug has a -44.491% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCOC(=O)C1CCN(C2=C(NS(=O)(=O)c3ccc(Cl)cc3)C(=O)c3ccccc3C2=O)CC1
b. CCOC(=O)c1cc(NC(=O)CNCC(c2ccccc2)N(C)C)cc(C(=O)OCC)c1.O=C(O)C(=O)O
c. Cc1ccc(C2Nc3ccccc3NC3=C2C(=O)OC(C)C3)cc1
d. COc1ccc(OC)c(NC(=O)COC(=O)Cc2ccc(Br)cc2)c1
e. COCc1cc(C)nc(SCC[N+](C)(C)CC(=O)c2ccc(Br)cc2)c1C#N.[Br-]
Answer: a. CCOC(=O)C1CCN(C2=C(NS(=O)(=O)c3ccc(Cl)cc3)C(=O)c3ccccc3C2=O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1CCN(C2=C(NS(=O)(=O)c3ccc(Cl)cc3)C(=O)c3ccccc3C2=O)CC1
CCOC(=O)C1CCN(C2=C(NS(=O)(=O)c3ccc(Cl)cc3)C(=O)c3ccccc3C2=O)CC1
4-chloro-N-[3-(4-ethoxycarbonylpiperidin-1-yl)-1,4-dioxonaphthalen-2-yl]benzenesulfonamide