Problem statement: Answer the multiple choice question.
Question: Which compound exhibits a -11.315% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CN(C(=O)COc1ccccc1C(=O)NCCc1ccccc1)c1ccccc1
b: Cc1noc(/C=C/N(C)C)c1S(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2)CC1
c: Cc1cc(Br)ccc1NC(=O)CN(C)C(=O)CSCc1ccccc1
d: O=C(CCCSc1nc2ccccc2[nH]1)NCc1ccccc1Cl
e: COc1cccc2cc(C(=O)N3CCCc4ccccc43)oc12
Answer: b. Cc1noc(/C=C/N(C)C)c1S(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1noc(/C=C/N(C)C)c1S(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2)CC1
Cc1noc(/C=C/N(C)C)c1S(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2)CC1
N-(4-chlorophenyl)-1-[[5-[(E)-2-(dimethylamino)ethenyl]-3-methyl-1,2-oxazol-4-yl]sulfonyl]piperidine-4-carboxamide