Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -3.810% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: Cc1ccnc(NC(=O)CCC(=O)N(CC(=O)NC(C)(C)C)c2ccc(F)c(Cl)c2)c1
b: CCOC(=O)c1ccc(NC(=O)CSc2nnc(NC(=O)c3ccc(S(=O)(=O)N4CCOCC4)cc3)s2)cc1
c: COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)N2CCCCC2c2cccnc2)cc1
d: O=Cc1sc([O-])nc1-[n+]1ccc2ccccc2c1
Answer: c. COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)N2CCCCC2c2cccnc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)N2CCCCC2c2cccnc2)cc1
COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)N2CCCCC2c2cccnc2)cc1
2-methoxy-N-[4-(2-pyridin-3-ylpiperidin-1-yl)sulfonylphenyl]benzamide