Problem statement: Answer the MCQ question.
Query: Which compound has a -1.808% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1cc(S(=O)(=O)N2CCCC2)ccc1OCC(=O)NC1CCCC1
(b) O=c1oc2ccccc2c(NCc2ccc(Cl)cc2)c1[N+](=O)[O-]
(c) CSc1ccc(CN2CCSCC2)cc1
(d) Cc1ccc(Cn2nc(C)c(NC(=O)C3(C)CC3(Br)Br)c2C)cc1
(e) Cc1ccccc1NC(=O)Cn1nnc(S(=O)(=O)c2ccc(C(C)(C)C)cc2)c1N
Answer: d. Cc1ccc(Cn2nc(C)c(NC(=O)C3(C)CC3(Br)Br)c2C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(Cn2nc(C)c(NC(=O)C3(C)CC3(Br)Br)c2C)cc1
Cc1ccc(Cn2nc(C)c(NC(=O)C3(C)CC3(Br)Br)c2C)cc1
2,2-dibromo-N-[3,5-dimethyl-1-[(4-methylphenyl)methyl]pyrazol-4-yl]-1-methylcyclopropane-1-carboxamide