Problem statement: Answer the MCQ question.
Query: Which drug has a -17.521% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1cc(/C=N/NC(=S)NC2CC3CC2C2C=CCC32)ccc1O
b.) O=P(O)(c1ccccc1)c1ccccc1O
c.) CN1CCN(C(CNC(=O)c2ccc(Br)o2)c2ccc(F)cc2)CC1
d.) C=CCn1c(C)nc2c(cnn2-c2ccccc2)c1=O
e.) CCOC(=O)c1ccc(NS(=O)(=O)c2cnc[nH]2)cc1
Answer: c. CN1CCN(C(CNC(=O)c2ccc(Br)o2)c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1CCN(C(CNC(=O)c2ccc(Br)o2)c2ccc(F)cc2)CC1
CN1CCN(C(CNC(=O)c2ccc(Br)o2)c2ccc(F)cc2)CC1
5-bromo-N-[2-(4-fluorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]furan-2-carboxamide