Problem statement: Answer the MCQ question.
Query: Which drug has a -45.921% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) CCOc1ncccc1C(=O)N1CCN(c2cc(Cl)ccc2C)CC1
b.) O=c1[nH]n(Cc2ccccc2)c(=O)c2ccccc12
c.) COc1ccc(CNC(=O)C[C@H]2C(=O)N(Cc3ccc(OC)cc3)C[C@@H]2Cc2ccccc2)cc1
d.) Cc1nn(C)c(C)c1/C=N/NC(=O)c1csc2ccccc12
Answer: c. COc1ccc(CNC(=O)C[C@H]2C(=O)N(Cc3ccc(OC)cc3)C[C@@H]2Cc2ccccc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C[C@H]2C(=O)N(Cc3ccc(OC)cc3)C[C@@H]2Cc2ccccc2)cc1
COc1ccc(CNC(=O)C[C@H]2C(=O)N(Cc3ccc(OC)cc3)C[C@@H]2Cc2ccccc2)cc1
2-[(3R,4R)-4-benzyl-1-[(4-methoxyphenyl)methyl]-2-oxopyrrolidin-3-yl]-N-[(4-methoxyphenyl)methyl]acetamide