Problem statement: Answer the MCQ question.
Question: Which drug has a -22.263% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CCOc1ccc(N2C(=O)c3ccc(C(=O)OCC(=O)N(CC)C4CCS(=O)(=O)C4)cc3C2=O)cc1
[b] COC(=O)/C=C1\C(=O)N(c2nc3ccccc3s2)C(=S)N1c1ccc(F)cc1
[c] COc1ccc(/C=N/NC(=O)c2[nH]ncc2Br)c(OC)c1
[d] CN1C(=O)C(=Cc2ccc(N3CCOCC3)c([N+](=O)[O-])c2)C(=O)N(C)C1=O
[e] Nc1nn2c(C(F)(F)F)cc(=O)[nH]c2c1N=Nc1cccc(F)c1
Answer: a. CCOc1ccc(N2C(=O)c3ccc(C(=O)OCC(=O)N(CC)C4CCS(=O)(=O)C4)cc3C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(N2C(=O)c3ccc(C(=O)OCC(=O)N(CC)C4CCS(=O)(=O)C4)cc3C2=O)cc1
CCOc1ccc(N2C(=O)c3ccc(C(=O)OCC(=O)N(CC)C4CCS(=O)(=O)C4)cc3C2=O)cc1
[2-[(1,1-dioxothiolan-3-yl)-ethylamino]-2-oxoethyl] 2-(4-ethoxyphenyl)-1,3-dioxoisoindole-5-carboxylate