Task: Answer the MCQ question.
Query: Which drug has a -4.080% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1ccccc1C1/C(=C(/O)c2ccccc2)C(=O)C(=O)N1CC(C)C
b.) O=C(NCCNC1CCC(c2ccccc2)CC1)c1ccc(F)cc1
c.) O=S(=O)(NCC(c1ccc2c(c1)OCO2)N1CCOCC1)c1ccc(Br)cc1
d.) CCn1c(COc2ccc3c(c2)CCCC3)nnc1SCC(=O)Nc1nccs1
e.) O=C(CSc1nnc(NC(=O)c2ccc(F)cc2)s1)NC1CCCC1
Answer: d. CCn1c(COc2ccc3c(c2)CCCC3)nnc1SCC(=O)Nc1nccs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCn1c(COc2ccc3c(c2)CCCC3)nnc1SCC(=O)Nc1nccs1
CCn1c(COc2ccc3c(c2)CCCC3)nnc1SCC(=O)Nc1nccs1
2-[[4-ethyl-5-(5,6,7,8-tetrahydronaphthalen-2-yloxymethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(1,3-thiazol-2-yl)acetamide