Problem statement: Answer the multiple-choice question.
Question: Which drug has a -8.129% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COCCNc1ccc(S(=O)(=O)N2CCCC2)cc1[N+](=O)[O-]
b) CC(C)N(CCCNC(=O)CC1Oc2ccccc2NC1=O)Cc1ccccc1
c) COC(=O)C1=C(C)N(Cc2ccccc2)C(=O)N[C@H]1c1cccs1
d) O=C(OCC(=O)C12CC3CC(CC(C3)C1)C2)c1ccc(O)cc1O
e) COc1ccc(NS(=O)(=O)c2cccc(C(=O)NNC(=O)c3ccccc3O)c2)cc1
Answer: c. COC(=O)C1=C(C)N(Cc2ccccc2)C(=O)N[C@H]1c1cccs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(C)N(Cc2ccccc2)C(=O)N[C@H]1c1cccs1
COC(=O)C1=C(C)N(Cc2ccccc2)C(=O)N[C@H]1c1cccs1
methyl (6R)-3-benzyl-4-methyl-2-oxo-6-thiophen-2-yl-1,6-dihydropyrimidine-5-carboxylate