Problem statement: Answer the multiple choice question.
Question: Which compound has a -34.143% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccc(OC)c(S(=O)(=O)Nc2ccc(-c3ccc4nnc(C)n4n3)cc2)c1
[b] COc1ccc(CNC(=O)C2CCCN2S(=O)(=O)c2ccc(Cl)cc2)cc1
[c] CCc1ccccc1N1C(=O)C2C3C=CC(CC3)C2C1=O
[d] COc1ccc(OC)c(CCNC(=O)C2CCN(c3nnc(-n4cccc4)s3)CC2)c1
[e] COc1ccc([N+](=O)[O-])cc1C(=O)NCCOc1ccc(Cl)cc1
Answer: d. COc1ccc(OC)c(CCNC(=O)C2CCN(c3nnc(-n4cccc4)s3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OC)c(CCNC(=O)C2CCN(c3nnc(-n4cccc4)s3)CC2)c1
COc1ccc(OC)c(CCNC(=O)C2CCN(c3nnc(-n4cccc4)s3)CC2)c1
N-[2-(2,5-dimethoxyphenyl)ethyl]-1-(5-pyrrol-1-yl-1,3,4-thiadiazol-2-yl)piperidine-4-carboxamide