Task: Answer the MCQ question.
Question: Which drug has a -8.781% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(S(=O)(=O)NCCOc2ccccc2)cc1F
(b) CN1CCN(Cc2c(O)ccc3cc(-c4ccccn4)c(=O)oc23)CC1
(c) COc1ccc(OC)c(/C=C/C(=O)N(C)CC(=O)Nc2ccc(N3CCOCC3)cc2)c1
(d) COc1cccc(C(=O)NNC2=CC(=O)CC(C)(C)C2)c1
(e) CC(C)c1nc(SCC(=O)c2c[nH]c3ccccc23)n[nH]1
Answer: c. COc1ccc(OC)c(/C=C/C(=O)N(C)CC(=O)Nc2ccc(N3CCOCC3)cc2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OC)c(/C=C/C(=O)N(C)CC(=O)Nc2ccc(N3CCOCC3)cc2)c1
COc1ccc(OC)c(/C=C/C(=O)N(C)CC(=O)Nc2ccc(N3CCOCC3)cc2)c1
(E)-3-(2,5-dimethoxyphenyl)-N-methyl-N-[2-(4-morpholin-4-ylanilino)-2-oxoethyl]prop-2-enamide