Problem statement: Answer the multiple-choice question.
Question: Which compound has a -26.689% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COCCNC(=O)CCn1nc(-c2ccc(C)cc2)ccc1=O
(b) COc1ccc(NC(=O)CSc2nnc(-c3ccccc3)n2Cc2ccco2)cc1OC
(c) Cn1nc(C(F)(F)F)c(-c2ccc(Br)cc2)c1NC(=O)c1ccco1
(d) CC(=O)C1C2c3ccccc3O[C@@]1(C)N=c1s/c(=C/c3ccoc3)c(=O)n12
(e) O=C(Cc1ccc(Cl)cc1)NCCCNC(=O)c1cccnc1
Answer: d. CC(=O)C1C2c3ccccc3O[C@@]1(C)N=c1s/c(=C/c3ccoc3)c(=O)n12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=O)C1C2c3ccccc3O[C@@]1(C)N=c1s/c(=C/c3ccoc3)c(=O)n12
CC(=O)C1C2c3ccccc3O[C@@]1(C)N=c1s/c(=C/c3ccoc3)c(=O)n12
(9R,13E)-16-acetyl-13-(furan-3-ylmethylidene)-9-methyl-8-oxa-12-thia-10,15-diazatetracyclo[7.6.1.02,7.011,15]hexadeca-2,4,6,10-tetraen-14-one