Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -0.916% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cn1ncc2c(N3CCCCC3)nc(NCCCO)nc21
b) Cc1ccc(SCCNC(=S)Nc2cc(C)ccc2C)cc1
c) Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3cc(=O)c4ccccc4o3)cc2)c1C
d) C[C@]12CS(=O)(=O)C[C@H]1SC(=S)N2c1ccccc1
e) Cn1cc(CN2CCCC(C(=O)c3cccs3)C2)c(-c2cccc(Cl)c2)n1
Answer: d. C[C@]12CS(=O)(=O)C[C@H]1SC(=S)N2c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C[C@]12CS(=O)(=O)C[C@H]1SC(=S)N2c1ccccc1
C[C@]12CS(=O)(=O)C[C@H]1SC(=S)N2c1ccccc1
(3aS,6aS)-3a-methyl-5,5-dioxo-3-phenyl-6,6a-dihydro-4H-thieno[3,4-d][1,3]thiazole-2-thione