Task: Answer the multiple choice question.
Question: Which drug has a -12.771% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCCN3CCOCC3)n2)cc1OC
(b) CN(CCC#N)C(=O)COC(=O)/C=C/c1cccs1
(c) COc1ccc(NC(=O)CCN2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)cc1
(d) Cc1c(C(=O)NC2CCCCC2)oc2ccccc12
(e) COC(=O)COc1ccc(-c2nccc(-c3ccc(Br)cc3)n2)cc1
Answer: c. COc1ccc(NC(=O)CCN2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)CCN2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)cc1
COc1ccc(NC(=O)CCN2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)cc1
3-[4-(2,5-dichlorophenyl)sulfonylpiperazin-1-yl]-N-(4-methoxyphenyl)propanamide