Problem statement: Answer the MCQ question.
Question: Which drug has a -3.859% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCOC(=O)C1ON2CCCCC2C1(O)C(F)(F)F
b) Cc1ccc(-n2ncc(C(=O)O)c2C2CCN(C(=O)OC(C)(C)C)CC2)cc1
c) Cc1ccc2c(c1)c1c3n2CCN=C3CCC1.Cl
d) O=C(/C=C/c1cccc([N+](=O)[O-])c1)c1ccc2c(c1)OCCO2
e) O=C(OCCN1C(=O)c2ccccc2C1=O)c1cc(=O)[nH]c2ccccc12
Answer: b. Cc1ccc(-n2ncc(C(=O)O)c2C2CCN(C(=O)OC(C)(C)C)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(-n2ncc(C(=O)O)c2C2CCN(C(=O)OC(C)(C)C)CC2)cc1
Cc1ccc(-n2ncc(C(=O)O)c2C2CCN(C(=O)OC(C)(C)C)CC2)cc1
1-(4-methylphenyl)-5-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]pyrazole-4-carboxylic acid