Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -12.045% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1CCCCC1
b. Cc1csc(NC(=O)c2cc(-c3ccccc3)nc3ccccc23)n1
c. O=C(Cn1nc(C(F)F)cc1C(F)F)NNC(=S)Nc1ccc([N+](=O)[O-])cc1
d. Cc1ccc(C(=O)NCCc2nnc3c(C(F)(F)F)cc(Cl)cn23)o1
Answer: a. COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1CCCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1CCCCC1
COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1CCCCC1
methyl (1R,5S)-3-(3-cyanophenyl)-8-(cyclohexylcarbamoyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate