Task: Answer the multiple-choice question.
Question: Which drug has a -70.735% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1cccc(S(=O)(=O)N(C)C)c1)CC2
b.) COc1ccc(N(C(C)C(=O)NN=C2CCCC2)S(C)(=O)=O)cc1
c.) C=C(C)C(=O)Nc1nnc(-c2cccs2)s1
d.) CCOC(=O)N1CCN(C(=O)CCc2ccc(S(=O)(=O)NCCc3ccccc3)cc2)CC1
Answer: a. COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1cccc(S(=O)(=O)N(C)C)c1)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1cccc(S(=O)(=O)N(C)C)c1)CC2
COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1cccc(S(=O)(=O)N(C)C)c1)CC2
3-(6,7-dimethoxy-1-thiophen-2-yl-3,4-dihydro-1H-isoquinoline-2-carbonyl)-N,N-dimethylbenzenesulfonamide