Problem statement: Answer the multiple-choice question.
Question: Which drug has a -60.041% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) CN1C[C@@H]2C(c3ccc(C(F)(F)F)cc3)C3(c4cccnc4)CC2(C3)[C@H]1c1ccccc1
b) CN1CCN(C(=O)c2c(NC(=O)c3ccco3)sc3c2CCC(C(C)(C)C)C3)CC1
c) COc1cccc(NC(=O)C2CC2)c1
d) CC(=O)c1nc(N2C(=O)CC(Cc3ccccc3)C2=O)sc1C
Answer: a. CN1C[C@@H]2C(c3ccc(C(F)(F)F)cc3)C3(c4cccnc4)CC2(C3)[C@H]1c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1C[C@@H]2C(c3ccc(C(F)(F)F)cc3)C3(c4cccnc4)CC2(C3)[C@H]1c1ccccc1
CN1C[C@@H]2C(c3ccc(C(F)(F)F)cc3)C3(c4cccnc4)CC2(C3)[C@H]1c1ccccc1
(2S,5R)-3-methyl-2-phenyl-7-pyridin-3-yl-6-[4-(trifluoromethyl)phenyl]-3-azatricyclo[5.1.1.01,5]nonane