Problem statement: Answer the MCQ question.
Question: Which drug has a 4.602% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CSc1ccccc1OCc1cc(C(=O)NCc2cccc(C)n2)no1
[b] CN(C)S(=O)(=O)N1CCC(Oc2ccc(C(=O)N3C[C@@H]4CCC[C@H]3C4)cc2)CC1
[c] Br.CN(CC(O)C[NH+]1CCOCC1)S(=O)(=O)[O-]
[d] CS(=O)(=O)N1CCN(C(=S)NCc2ccc(F)cc2)CC1
[e] COc1cc([C@H]2[C@@H]3CCCC[C@]3(O)CCN2CC(=O)Nc2ccc(C)cc2C)ccc1O
Answer: b. CN(C)S(=O)(=O)N1CCC(Oc2ccc(C(=O)N3C[C@@H]4CCC[C@H]3C4)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(C)S(=O)(=O)N1CCC(Oc2ccc(C(=O)N3C[C@@H]4CCC[C@H]3C4)cc2)CC1
CN(C)S(=O)(=O)N1CCC(Oc2ccc(C(=O)N3C[C@@H]4CCC[C@H]3C4)cc2)CC1
4-[4-[(1R,5S)-6-azabicyclo[3.2.1]octane-6-carbonyl]phenoxy]-N,N-dimethylpiperidine-1-sulfonamide