Problem statement: Answer the multiple choice question.
Question: Which compound has a -24.105% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CCN1CCN(c2nc3c(c(=O)n(C)c(=O)n3C)n2Cc2cccc3ccccc23)CC1
b.) Cc1ccc(NC(=S)Nc2cccc3cnccc23)cc1C
c.) CCNC(=S)N/N=C/c1c(Cl)cccc1Cl
d.) Cc1cccc(N(Cc2ccccc2)C(=O)C2CCN(C(=O)c3ccccc3C)CC2)c1
e.) O=C1COc2ccc(C(=O)COC(=O)CNS(=O)(=O)c3cccc(F)c3)cc2N1
Answer: a. CCN1CCN(c2nc3c(c(=O)n(C)c(=O)n3C)n2Cc2cccc3ccccc23)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1CCN(c2nc3c(c(=O)n(C)c(=O)n3C)n2Cc2cccc3ccccc23)CC1
CCN1CCN(c2nc3c(c(=O)n(C)c(=O)n3C)n2Cc2cccc3ccccc23)CC1
8-(4-ethylpiperazin-1-yl)-1,3-dimethyl-7-(naphthalen-1-ylmethyl)purine-2,6-dione