Problem statement: Answer the MCQ question.
Query: Which compound exhibits a 14.068% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CCOc1ccc(C(=O)OCc2nnc(-c3cccs3)o2)cc1OC
b: COc1ccccc1NC(=O)N1CCCC1C(=O)NCc1ccccc1
c: CCOc1ccccc1NC(=O)CN(c1ccc(OC)cc1)S(=O)(=O)c1c(C)[nH]c(=O)[nH]c1=O
d: CCOC(=O)C1CCCN(Cc2cccs2)C1
e: O=C(CN(C(=O)c1csnn1)c1cccc(Cl)c1)NC1CCCC1
Answer: c. CCOc1ccccc1NC(=O)CN(c1ccc(OC)cc1)S(=O)(=O)c1c(C)[nH]c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccccc1NC(=O)CN(c1ccc(OC)cc1)S(=O)(=O)c1c(C)[nH]c(=O)[nH]c1=O
CCOc1ccccc1NC(=O)CN(c1ccc(OC)cc1)S(=O)(=O)c1c(C)[nH]c(=O)[nH]c1=O
N-(2-ethoxyphenyl)-2-[4-methoxy-N-[(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)sulfonyl]anilino]acetamide