Problem statement: Answer the multiple-choice question.
Question: Which drug has a -40.695% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. COc1ccccc1C(=O)N(CCN(C)C)c1nc2cc(C)cc(C)c2s1.Cl
b. CCCCN(CCO)c1ncnc2sc(-c3ccccc3)cc12
c. CCCCn1nc(C(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)c2ccccc2c1=O
d. Cc1nn(C(C)C(=O)NCCCN2CCCC2)c(=O)c2nn(-c3ccccc3)c(C)c12
Answer: c. CCCCn1nc(C(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)c2ccccc2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCn1nc(C(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)c2ccccc2c1=O
CCCCn1nc(C(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)c2ccccc2c1=O
4-[4-(benzenesulfonyl)piperazine-1-carbonyl]-2-butylbenzo[d]pyridazin-1-one