Problem statement: Answer the multiple choice question.
Query: Which drug has a -8.116% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1ccc(-n2c(N)c(Br)c(=O)[nH]c2=O)cc1
b c1ccc(-n2c(-c3cccs3)nc3nc4ccccc4nc32)cc1
c CCOC(=O)c1ccc2ncc(C(=O)OCC)c(NCCN3CCOCC3)c2c1
d Cn1cc(Br)c(-c2cccc(N3C(=O)CC(C)(C)CC3=O)c2)n1
e COc1cccc(NC(=O)CN(C)CC(=O)c2c(N)n(Cc3ccccc3)c(=O)n(C)c2=O)c1
Answer: e. COc1cccc(NC(=O)CN(C)CC(=O)c2c(N)n(Cc3ccccc3)c(=O)n(C)c2=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(NC(=O)CN(C)CC(=O)c2c(N)n(Cc3ccccc3)c(=O)n(C)c2=O)c1
COc1cccc(NC(=O)CN(C)CC(=O)c2c(N)n(Cc3ccccc3)c(=O)n(C)c2=O)c1
2-[[2-(6-amino-1-benzyl-3-methyl-2,4-dioxopyrimidin-5-yl)-2-oxoethyl]-methylamino]-N-(3-methoxyphenyl)acetamide