Problem statement: Answer the multiple-choice question.
Query: Which compound has a 0.719% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CC1CN(C(=O)c2cc(F)c(F)cc2Cl)CC(C)O1
[b] N#Cc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3cccc(C(=O)NC4CC4)c3)CC2)cc1
[c] COc1cc2c(cc1OC)C(C(=O)Nc1cc(OC)c(OC)c(OC)c1)C(c1cccnc1)N(C)C2=O
[d] O=C(Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)C1=NN(c2ccccc2)C(=O)CC1
[e] O=Cc1ccc(N2CCCCC2)cc1
Answer: b. N#Cc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3cccc(C(=O)NC4CC4)c3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#Cc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3cccc(C(=O)NC4CC4)c3)CC2)cc1
N#Cc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3cccc(C(=O)NC4CC4)c3)CC2)cc1
1-(4-cyanophenyl)sulfonyl-N-[3-(cyclopropylcarbamoyl)phenyl]piperidine-4-carboxamide