Problem statement: Answer the MCQ question.
Query: Which compound has a -24.242% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1ccc(OC)c(/C=N/NC2=NS(=O)(=O)c3ccccc32)c1
b.) CCOC(=O)C1=C(N)N(c2ccc(C)cc2)C2=C(C(=O)CCC2)C1c1cccs1
c.) CCc1ccc(Nc2nc(N)nc(CSc3nc4ccccc4s3)n2)cc1
d.) O=C(COc1ccc2c3c(c(=O)oc2c1)CCC3)N1CCN(c2ccc(F)cc2)CC1
e.) Cc1ccc(S(=O)(=O)c2nc(S(=O)(=O)c3ccc(C)cc3)c(NCc3ccco3)s2)cc1
Answer: d. O=C(COc1ccc2c3c(c(=O)oc2c1)CCC3)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COc1ccc2c3c(c(=O)oc2c1)CCC3)N1CCN(c2ccc(F)cc2)CC1
O=C(COc1ccc2c3c(c(=O)oc2c1)CCC3)N1CCN(c2ccc(F)cc2)CC1
1-[4-(4-fluorophenyl)piperazin-1-yl]-2-[(4-oxo-2,3-dihydro-1H-cyclopenta[c]chromen-7-yl)oxy]ethanone