Problem statement: Answer the multiple choice question.
Question: Which compound has a -1.430% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. CC(=O)Nc1ccc(NC(=O)C(C)OC(=O)CNC(=O)c2cccs2)cc1
b. Cc1cccc(C(=O)NCC(C)NC(=O)c2cccc(C)c2)c1
c. COc1ccc(-n2ncc3c(=O)n(CC(=O)N4c5ccccc5CC4C)cnc32)cc1
d. CC(=O)n1cc(-c2ccncc2)c2ccccc21.Cl
Answer: c. COc1ccc(-n2ncc3c(=O)n(CC(=O)N4c5ccccc5CC4C)cnc32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-n2ncc3c(=O)n(CC(=O)N4c5ccccc5CC4C)cnc32)cc1
COc1ccc(-n2ncc3c(=O)n(CC(=O)N4c5ccccc5CC4C)cnc32)cc1
1-(4-methoxyphenyl)-5-[2-(2-methyl-2,3-dihydroindol-1-yl)-2-oxoethyl]pyrazolo[3,4-d]pyrimidin-4-one