Problem statement: Answer the multiple choice question.
Question: Which compound exhibits a 13.520% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCOC(=O)C1CCCN(Cc2nc(CC3CC3)no2)C1
(b) CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CN(CC3CCCO3)C(=O)[C@@]12C
(c) CN(C)c1ccc(C(=O)Nc2nc3c(s2)CCCC3)cc1
(d) COc1ccc(CC(=O)Nc2ccc(S(=O)(=O)N(C)C3CCN(C)CC3)cc2)cc1
(e) CC(C)(C)C(=O)Nc1cccc(C(=O)c2cccc(NC(=O)C(C)(C)C)c2)c1
Answer: b. CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CN(CC3CCCO3)C(=O)[C@@]12C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CN(CC3CCCO3)C(=O)[C@@]12C
CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CN(CC3CCCO3)C(=O)[C@@]12C
ethyl(1R,10R,11S,12R)-4-chloro-12-methyl-13,16-dioxo-14-(oxolan-2-ylmethyl)-8-oxa-14,17-diazatetracyclo[8.7.0.02,7.012,17]heptadeca-2(7),3,5-triene-11-carboxylate