Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -58.400% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) NS(=O)(=O)c1ccc(CCNC(=O)C2CCCO2)cc1
b) O=C(CN1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1)N/N=C/c1cccs1
c) Cc1ccc(S(=O)(=O)N2CCN(C(=O)CSc3nnnn3C)CC2)c(C)c1
d) C=CCN(c1ccccc1)S(=O)(=O)c1cccc(C(=O)O)c1
e) O=C1[C@@H]2Cc3c([nH]c4ccccc34)C(c3ccccc3)N2C(=O)CN1CCO
Answer: b. O=C(CN1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1)N/N=C/c1cccs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CN1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1)N/N=C/c1cccs1
O=C(CN1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1)N/N=C/c1cccs1
2-[4-(4-bromophenyl)sulfonylpiperazin-1-yl]-N-[(E)-thiophen-2-ylmethylideneamino]acetamide