Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -2.171% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) CCOc1cc(N2CCOCC2)c(OCC)cc1NC(=O)c1ccccc1C
b) Cc1ccc(/C=C2/N=C(c3ccccc3)NNC2=O)cc1
c) CC(=O)O[C@H]1CSC[C@H]1NC(=O)c1ccccc1
d) O=C(NCc1ccncc1)C(F)(F)C(F)(F)C(=O)NCc1ccncc1
Answer: d. O=C(NCc1ccncc1)C(F)(F)C(F)(F)C(=O)NCc1ccncc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCc1ccncc1)C(F)(F)C(F)(F)C(=O)NCc1ccncc1
O=C(NCc1ccncc1)C(F)(F)C(F)(F)C(=O)NCc1ccncc1
2,2,3,3-tetrafluoro-N,N'-bis(pyridin-4-ylmethyl)butanediamide