Problem statement: Answer the MCQ question.
Query: Which compound has a -2.022% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1ccc(NC(=O)CNC(=O)Cc2cccc3ccccc23)nc1
(b) COc1cc(/C=N/NC(=O)c2nonc2C)ccc1O
(c) CCOC(=O)c1c(NC(=S)N2CCN(C)CC2)sc2c1CCN(C(=O)OCC)C2
(d) CCOc1ccc(/C(O)=C2/C(=O)C(=O)N(CCN(CC)CC)C2c2ccco2)cc1
(e) CCC(=O)/C(=C(/O)c1ccccc1)c1nc2ccccc2[nH]1
Answer: c. CCOC(=O)c1c(NC(=S)N2CCN(C)CC2)sc2c1CCN(C(=O)OCC)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1c(NC(=S)N2CCN(C)CC2)sc2c1CCN(C(=O)OCC)C2
CCOC(=O)c1c(NC(=S)N2CCN(C)CC2)sc2c1CCN(C(=O)OCC)C2
diethyl 2-[(4-methylpiperazine-1-carbothioyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3,6-dicarboxylate