Problem statement: Answer the MCQ question.
Query: Which drug has a -48.854% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. COC(=O)C1=C(CCc2ccccc2)NC(=O)NC1c1ccc([N+](=O)[O-])cc1
b. CC(C)C1Cc2nc(Cl)c(C#N)cc2CO1
c. Cc1cc(C)c(C)c(S(=O)(=O)N2CCC(C(=O)NCC(c3ccccc3)N(C)C)CC2)c1C
d. Cc1ccc(NC(=O)[C@@H]2CCCN2S(=O)(=O)c2ccccc2F)cc1
Answer: c. Cc1cc(C)c(C)c(S(=O)(=O)N2CCC(C(=O)NCC(c3ccccc3)N(C)C)CC2)c1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cc(C)c(C)c(S(=O)(=O)N2CCC(C(=O)NCC(c3ccccc3)N(C)C)CC2)c1C
Cc1cc(C)c(C)c(S(=O)(=O)N2CCC(C(=O)NCC(c3ccccc3)N(C)C)CC2)c1C
N-[2-(dimethylamino)-2-phenylethyl]-1-(2,3,5,6-tetramethylphenyl)sulfonylpiperidine-4-carboxamide