Problem statement: Answer the multiple choice question.
Question: Which drug has a -22.861% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) N#Cc1cc(-c2cccc(Cl)c2)c[nH]c1=O
b) O=C(NCc1ccccc1Cl)c1ccc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)cc1
c) CCOC(=O)CSc1cc(CS(=O)(=O)c2ccccc2)nc(-c2ccccc2)n1
d) Cn1c(OCc2ccco2)nc2c1c(=O)n(Cc1ccc(Cl)c(Cl)c1)c(=O)n2C
e) CCOC(=O)C1CCN(C2=NC(=O)/C(=C/c3ccccc3OC)S2)CC1
Answer: e. CCOC(=O)C1CCN(C2=NC(=O)/C(=C/c3ccccc3OC)S2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1CCN(C2=NC(=O)/C(=C/c3ccccc3OC)S2)CC1
CCOC(=O)C1CCN(C2=NC(=O)/C(=C/c3ccccc3OC)S2)CC1
ethyl 1-[(5Z)-5-[(2-methoxyphenyl)methylidene]-4-oxo-1,3-thiazol-2-yl]piperidine-4-carboxylate