Problem statement: Answer the multiple choice question.
Question: Which drug has a -3.745% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. Cc1cc(C)n(C(=O)/C(C#N)=C/N(C)C)n1
b. CCOC(=O)c1cc(C(=O)NN)c(C)nc1C
c. O=C(/C(=C\c1ccccc1)c1nc2ccccc2[nH]1)c1ccc(Cl)cc1
d. Cc1ccc(S(=O)(=O)CC(O)COc2ccccc2C#N)cc1
e. COc1ccc(N2CCN(C3CC(=O)N(Cc4ccc(N5CCCC5=O)cc4)C3=O)CC2)cc1
Answer: e. COc1ccc(N2CCN(C3CC(=O)N(Cc4ccc(N5CCCC5=O)cc4)C3=O)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(C3CC(=O)N(Cc4ccc(N5CCCC5=O)cc4)C3=O)CC2)cc1
COc1ccc(N2CCN(C3CC(=O)N(Cc4ccc(N5CCCC5=O)cc4)C3=O)CC2)cc1
3-[4-(4-methoxyphenyl)piperazin-1-yl]-1-[[4-(2-oxopyrrolidin-1-yl)phenyl]methyl]pyrrolidine-2,5-dione