Problem statement: Answer the multiple-choice question.
Question: Which drug has a -9.362% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1ccc(SCCC(=O)NNS(=O)(=O)c2cn(C)cn2)cc1
b.) COC(=O)c1cccc(NC(=S)Nc2ccc(Cl)c(Cl)c2)c1
c.) CC(C)C(OC(=O)c1nsc(Cl)c1Cl)C(=O)NC(C)(C)C
d.) COc1ccc(-n2c3c(cc(C(=O)NCC(=O)c4ccccc4)c2=O)C(=O)CC(C)(C)C3)cc1
e.) CCc1sc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1Br
Answer: e. CCc1sc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1Br
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1sc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1Br
CCc1sc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1Br
4-bromo-5-ethyl-N-[2-(4-sulfamoylphenyl)ethyl]thiophene-2-carboxamide