Problem statement: Answer the multiple-choice question.
Question: Which drug has a -61.433% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCS(=O)(=O)NCc1ccc2c(c1)cc(C)n2C
b. CCN1CCN(C(CNS(=O)(=O)c2cccs2)c2cccnc2)CC1
c. CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2ccc3c(c2)OCO3)c1
d. O=C1CSC(=NC2CCCCC2)N1
e. COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1[C@@H](NC(C)=O)CC2
Answer: b. CCN1CCN(C(CNS(=O)(=O)c2cccs2)c2cccnc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1CCN(C(CNS(=O)(=O)c2cccs2)c2cccnc2)CC1
CCN1CCN(C(CNS(=O)(=O)c2cccs2)c2cccnc2)CC1
N-[2-(4-ethyl-1,4-diazinan-1-yl)-2-pyridin-3-ylethyl]thiophene-2-sulfonamide