Task: Answer the multiple-choice question.
Question: Which compound has a -47.336% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C(N/N=C\c1ccc(F)cc1)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F
b) COc1ccc(N2CCN(CC(=O)Nc3nc(C)cs3)CC2)cc1
c) CC(C)CN(C(=O)CCC(=O)OCc1ccc(Cl)cc1Cl)c1c(N)n(CC(C)C)c(=O)[nH]c1=O
d) CCCC(=O)Nc1nnc(S(=O)(=O)N(CC)c2ccc(OC)cc2)s1
e) Cc1onc(-c2ccccc2Cl)c1C(=O)N1CCC(C)CC1
Answer: c. CC(C)CN(C(=O)CCC(=O)OCc1ccc(Cl)cc1Cl)c1c(N)n(CC(C)C)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)CN(C(=O)CCC(=O)OCc1ccc(Cl)cc1Cl)c1c(N)n(CC(C)C)c(=O)[nH]c1=O
CC(C)CN(C(=O)CCC(=O)OCc1ccc(Cl)cc1Cl)c1c(N)n(CC(C)C)c(=O)[nH]c1=O
(2,4-dichlorophenyl)methyl 4-[[6-amino-1-(2-methylpropyl)-2,4-dioxopyrimidin-5-yl]-(2-methylpropyl)amino]-4-oxobutanoate