Problem statement: Answer the MCQ question.
Question: Which drug has a 14.040% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
(a) COc1ccc(OC)c(CCNC(=O)CCC(=O)N2CCOc3ccc(C)cc32)c1
(b) CSC1=NCCN1C(=O)c1ccco1
(c) CN(C)S(=O)(=O)c1ccc(Cl)c(NC(=O)CN2C(=O)NC3(CCCC3)C2=O)c1
(d) CCCCn1c(N)c(N(CCOC)C(=O)C2CC(=O)N(Cc3ccco3)C2)c(=O)[nH]c1=O
Answer: d. CCCCn1c(N)c(N(CCOC)C(=O)C2CC(=O)N(Cc3ccco3)C2)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCn1c(N)c(N(CCOC)C(=O)C2CC(=O)N(Cc3ccco3)C2)c(=O)[nH]c1=O
CCCCn1c(N)c(N(CCOC)C(=O)C2CC(=O)N(Cc3ccco3)C2)c(=O)[nH]c1=O
N-(6-amino-1-butyl-2,4-dioxopyrimidin-5-yl)-1-(furan-2-ylmethyl)-N-(2-methoxyethyl)-5-oxopyrrolidine-3-carboxamide