Problem statement: Answer the MCQ question.
Question: Which compound has a -7.176% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1ccc(Cn2c(CCNc3nc(-c4ccc(C)cc4)cs3)nc3cc(C(=O)NCCCO)ccc32)cc1
b) Cc1ccc(C(=O)NCC(C)NC(=O)c2ccc(C)c(C)c2)cc1C
c) Cn1c(-c2ccc(F)cc2)cnc1SCC(=O)N1CCCc2ccccc21
d) O=C(CCNS(=O)(=O)c1ccccc1C(F)(F)F)NCC(c1ccco1)N1CCCCC1
e) O=C(COc1ccccc1Cl)Nc1ccccc1C(=O)NC1CC1
Answer: a. Cc1ccc(Cn2c(CCNc3nc(-c4ccc(C)cc4)cs3)nc3cc(C(=O)NCCCO)ccc32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(Cn2c(CCNc3nc(-c4ccc(C)cc4)cs3)nc3cc(C(=O)NCCCO)ccc32)cc1
Cc1ccc(Cn2c(CCNc3nc(-c4ccc(C)cc4)cs3)nc3cc(C(=O)NCCCO)ccc32)cc1
N-(3-hydroxypropyl)-1-[(4-methylphenyl)methyl]-2-[2-[[4-(4-methylphenyl)-1,3-thiazol-2-yl]amino]ethyl]benzimidazole-5-carboxamide