Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -24.449% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CC(=O)Nc1ccc(C(=O)CN2C(=O)NC3(CCOc4ccccc43)C2=O)c(F)c1
b) CCn1c(C)nc2cc(C(=O)NNC(=O)Nc3ccc(Cl)c(Cl)c3)ccc21
c) O=C(NC1CCCN(c2ccc(C(F)(F)F)cn2)C1)c1ccncc1
d) COc1ccc2[nH]cc(C(=O)CNc3nc(C)cs3)c2c1.I
e) O=[N+]([O-])c1cccc(S(=O)(=O)Nc2ccc(Cc3ccncc3)cc2)c1
Answer: d. COc1ccc2[nH]cc(C(=O)CNc3nc(C)cs3)c2c1.I
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2[nH]cc(C(=O)CNc3nc(C)cs3)c2c1.I
COc1ccc2[nH]cc(C(=O)CNc3nc(C)cs3)c2c1.I
1-(5-methoxy-1H-indol-3-yl)-2-[(4-methyl-1,3-thiazol-2-yl)amino]ethanone;hydroiodide