Problem statement: Answer the MCQ question.
Question: Which drug has a -18.103% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCOC(=O)c1sc(/S(C)=N\S(=O)(=O)c2cccc(Cl)c2)c2c1CCC=C2
(b) CS(=O)(=O)N(CC(=O)O)c1ccc2c(c1)OCO2
(c) O=C(c1cnn2c(C(F)(F)F)cc(-c3cccs3)nc12)N1CCN(C(c2ccccc2)c2ccccc2)CC1
(d) COc1ccccc1N1CCN(C(=O)COc2ccc(Cl)cc2Br)CC1
(e) O=C(CN1C(=O)NC2(CCCC2)C1=O)OCCOc1ccc(Br)cc1
Answer: d. COc1ccccc1N1CCN(C(=O)COc2ccc(Cl)cc2Br)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CCN(C(=O)COc2ccc(Cl)cc2Br)CC1
COc1ccccc1N1CCN(C(=O)COc2ccc(Cl)cc2Br)CC1
2-(2-bromo-4-chlorophenoxy)-1-[4-(6-methoxyphenyl)piperazin-1-yl]ethanone