Problem statement: Answer the multiple-choice question.
Query: Which drug has a -25.216% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1cccc(C(=O)N/N=C/c2cn[nH]c2-c2ccc(OC)cc2OC)c1
b CCCN(CC(=O)Nc1ccccc1C)C(=O)c1cccc(S(=O)(=O)N2CCN(c3ccccc3)CC2)c1
c CC(=O)Nc1ccc(OC(=O)c2cc3cc(Br)ccc3oc2=O)cc1
d CCOc1ccc(S(=O)(=O)N2CCCC(C(=O)Nc3ccccc3)C2)cc1
e CC1CCN(C2=NC(=O)/C(=C/c3ccccc3F)S2)CC1
Answer: e. CC1CCN(C2=NC(=O)/C(=C/c3ccccc3F)S2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1CCN(C2=NC(=O)/C(=C/c3ccccc3F)S2)CC1
CC1CCN(C2=NC(=O)/C(=C/c3ccccc3F)S2)CC1
(5Z)-5-[(2-fluorophenyl)methylidene]-2-(4-methylpiperidin-1-yl)-1,3-thiazol-4-one