Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 4.385% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Brc1cccc(-c2n[nH]c(-c3ccccc3)n2)c1
b CN(C)C(CNC(=O)CCC(=O)c1ccc(Br)cc1)c1ccccc1
c COc1ccccc1N1CCN(C2CCCN(C(=O)Cn3cccn3)C2)CC1
d O=C(OCc1ccc([N+](=O)[O-])cc1)C1CCN(S(=O)(=O)c2ccccc2)CC1
e O=S(=O)(c1cccc2cccnc12)N1CCCCC1
Answer: c. COc1ccccc1N1CCN(C2CCCN(C(=O)Cn3cccn3)C2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CCN(C2CCCN(C(=O)Cn3cccn3)C2)CC1
COc1ccccc1N1CCN(C2CCCN(C(=O)Cn3cccn3)C2)CC1
1-[3-[4-(2-methoxyphenyl)piperazin-1-yl]piperidin-1-yl]-2-pyrazol-1-ylethanone