Problem statement: Answer the multiple choice question.
Query: Which compound has a -13.278% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCCC(=O)Nc1ccc(N2CCN(C(=O)c3cc4ccccc4o3)CC2)cc1
b) COc1ccc([C@H]2CC(=O)C=C(c3cc(F)ccc3F)C2)cc1OC
c) CC(C)N1C(=O)C2C(C(=O)NCc3ccccc3)C3C=CC2(O3)C1C(=O)NC(C)(C)C
d) CCc1cc(C(=O)NNC(=S)NC(C)c2ccccc2)cs1
e) CC(OC(=O)c1ccncc1)C(=O)Nc1cccc([N+](=O)[O-])c1
Answer: b. COc1ccc([C@H]2CC(=O)C=C(c3cc(F)ccc3F)C2)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@H]2CC(=O)C=C(c3cc(F)ccc3F)C2)cc1OC
COc1ccc([C@H]2CC(=O)C=C(c3cc(F)ccc3F)C2)cc1OC
(5R)-3-(2,5-difluorophenyl)-5-(3,4-dimethoxyphenyl)cyclohex-2-en-1-one