Problem statement: Answer the MCQ question.
Question: Which drug has a 1.850% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a.) CN(CCCN1CCOCC1)C(=O)c1cc(COc2cccc(C(F)(F)F)c2)on1
b.) Cc1onc(-c2ccccc2)c1C(=O)NCC1COc2ccccc2O1
c.) COc1ccc(-c2ccoc2)cc1[C@H]1[C@H]2C=CC[C@@H](C)[C@@H]2C(=O)N1Cc1ccccc1
Answer: c. COc1ccc(-c2ccoc2)cc1[C@H]1[C@H]2C=CC[C@@H](C)[C@@H]2C(=O)N1Cc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2ccoc2)cc1[C@H]1[C@H]2C=CC[C@@H](C)[C@@H]2C(=O)N1Cc1ccccc1
COc1ccc(-c2ccoc2)cc1[C@H]1[C@H]2C=CC[C@@H](C)[C@@H]2C(=O)N1Cc1ccccc1
(3R,3aS,7R,7aS)-2-benzyl-3-[5-(furan-3-yl)-2-methoxyphenyl]-7-methyl-3a,6,7,7a-tetrahydro-3H-isoindol-1-one