Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -5.651% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: C[N+]1(CC(=O)Nc2ccccc2Cl)CCN(C(=O)c2cccs2)CC1.[Cl-]
b: COc1ccccc1NC(=O)c1sc2nc(-c3ccco3)ccc2c1N
c: Cc1ccccc1OCCCCn1c(CO)nc2ccccc21
d: COc1cccc(CNC(=O)C2=C(C)C(=O)OC23CCC(C)CC3)c1
e: CN(C(=O)CSc1nnc(COc2ccccc2F)n1N)C1CCCCC1
Answer: d. COc1cccc(CNC(=O)C2=C(C)C(=O)OC23CCC(C)CC3)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)C2=C(C)C(=O)OC23CCC(C)CC3)c1
COc1cccc(CNC(=O)C2=C(C)C(=O)OC23CCC(C)CC3)c1
N-[(3-methoxyphenyl)methyl]-3,8-dimethyl-2-oxo-1-oxaspiro[4.5]dec-3-ene-4-carboxamide