Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 2.164% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCOC(=O)N1CCN(C(=O)Cc2ccsc2)CC1
b. COc1ccc2nc(C)c3c(c2c1)OC(C(C)(Cl)Br)C3
c. Cc1nnc(SCC(=O)N2CCCC(N3CCN(c4ccc(F)cc4)CC3)C2)o1
d. COC(=O)c1c(SCC(=O)Nc2ccc(C)c(C)c2)nc(=O)[nH]c1C
e. O=C(CN1C(=O)CCS(=O)(=O)c2ccccc21)NCCc1ccccc1
Answer: d. COC(=O)c1c(SCC(=O)Nc2ccc(C)c(C)c2)nc(=O)[nH]c1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1c(SCC(=O)Nc2ccc(C)c(C)c2)nc(=O)[nH]c1C
COC(=O)c1c(SCC(=O)Nc2ccc(C)c(C)c2)nc(=O)[nH]c1C
methyl 4-[2-(3,4-dimethylanilino)-2-oxoethyl]sulfanyl-6-methyl-2-oxo-1H-pyrimidine-5-carboxylate