Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -20.602% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cc1ccc(NC(=O)C2(c3ccccc3)CCCC2)nc1
[b] COc1ccc(CCNC(=O)C(=O)NCCC2CCCCN2S(=O)(=O)c2cccs2)cc1
[c] O=C(Nc1ccc(Br)cc1)C1CCCN(C2=NS(=O)(=O)c3ccccc32)C1
[d] COc1ccc(/C=C\C(=O)CC(O)(c2ccccc2)C(F)(F)F)cc1
[e] CN(C)[C@@H](COC(C)(C)C)c1nnc([C@H](CC(=O)OC(C)(C)C)NC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)o1
Answer: e. CN(C)[C@@H](COC(C)(C)C)c1nnc([C@H](CC(=O)OC(C)(C)C)NC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(C)[C@@H](COC(C)(C)C)c1nnc([C@H](CC(=O)OC(C)(C)C)NC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)o1
CN(C)[C@@H](COC(C)(C)C)c1nnc([C@H](CC(=O)OC(C)(C)C)NC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)o1
tert-butyl 4-[[(1S)-1-[5-[(1S)-1-(dimethylamino)-2-[(2-methylpropan-2-yl)oxy]ethyl]-1,3,4-oxadiazol-2-yl]-3-[(2-methylpropan-2-yl)oxy]-3-oxopropyl]carbamoyl]piperidine-1-carboxylate