Problem statement: Answer the multiple choice question.
Query: Which drug has a 21.286% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) Cc1noc(C)c1S(=O)(=O)Nc1ccc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1
(b) COCCn1c(=O)[nH]c2cc(C(=O)Nc3ccc(OC)c(Cl)c3)ccc2c1=O
(c) CCOC(=O)Cc1nn(Cc2nc(-c3ccc(C#N)cc3)cs2)c(=O)c2ccccc12
(d) COC(=O)C1=C(C)N(CCc2cc(OC)c(OC)c(OC)c2)C(=O)N[C@H]1c1cccs1
Answer: d. COC(=O)C1=C(C)N(CCc2cc(OC)c(OC)c(OC)c2)C(=O)N[C@H]1c1cccs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(C)N(CCc2cc(OC)c(OC)c(OC)c2)C(=O)N[C@H]1c1cccs1
COC(=O)C1=C(C)N(CCc2cc(OC)c(OC)c(OC)c2)C(=O)N[C@H]1c1cccs1
methyl (6R)-4-methyl-2-oxo-6-thiophen-2-yl-3-[2-(3,4,5-trimethoxyphenyl)ethyl]-1,6-dihydropyrimidine-5-carboxylate