Problem statement: Answer the MCQ question.
Question: Which drug has a -7.585% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
(a) COc1ccc(Cc2nnc(NC(=O)c3cccs3)s2)cc1OC
(b) Cc1c(NC(=O)CSC(=S)N2CCCC2)c(=O)n(-c2ccccc2)n1C
(c) COC(=O)C1=C(c2ccc(F)cc2OCc2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccccc1
(d) O=C(Cn1c(-c2cscn2)nc2ccccc21)Nc1ccc(Cl)cc1
Answer: d. O=C(Cn1c(-c2cscn2)nc2ccccc21)Nc1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Cn1c(-c2cscn2)nc2ccccc21)Nc1ccc(Cl)cc1
O=C(Cn1c(-c2cscn2)nc2ccccc21)Nc1ccc(Cl)cc1
N-(4-chlorophenyl)-2-[2-(1,3-thiazol-4-yl)benzimidazol-1-yl]acetamide