Task: Answer the multiple-choice question.
Question: Which compound has a -18.597% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(CCNC(=O)CSc2nnnn2-c2ccc(OC)c(OC)c2)cc1OC
b) COCC1CCN(C(=O)c2cc(COc3ccc(OC)c4ccccc34)on2)C1
c) O=C(CSc1nnc2nnc3ccccc3n12)N1CCOCC1
d) Cc1ccc(NS(=O)(=O)c2ccc3c(c2)NC(=O)C(C)C(=O)N3)cc1C
e) Cc1nn(C)c(Cl)c1CN1CCCC(CCC(=O)NCc2ccccc2F)C1
Answer: b. COCC1CCN(C(=O)c2cc(COc3ccc(OC)c4ccccc34)on2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCC1CCN(C(=O)c2cc(COc3ccc(OC)c4ccccc34)on2)C1
COCC1CCN(C(=O)c2cc(COc3ccc(OC)c4ccccc34)on2)C1
[3-(methoxymethyl)pyrrolidin-1-yl]-[5-[(4-methoxynaphthalen-1-yl)oxymethyl]-1,2-oxazol-3-yl]methanone