Problem statement: Answer the MCQ question.
Question: Which compound has a -22.798% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1cc(C(=O)OCC(=O)NCCCc2ccccc2)ccc1OCC(C)C
[b] COc1ccc(OC)c(CCNC(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)c1
[c] O=C(COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccco1)NC(c1ccccc1)c1ccccc1
[d] CCO[C@@H]1OC(C(=O)O)=C[C@H](c2cn(C(C)=O)c3ccccc23)[C@H]1CCCO
[e] CCOC(=O)N1CCN(C2CCCN(C(=O)c3ccccc3SC)C2)CC1
Answer: b. COc1ccc(OC)c(CCNC(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OC)c(CCNC(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)c1
COc1ccc(OC)c(CCNC(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)c1
N-[2-(2,5-dimethoxyphenyl)ethyl]-4-methyl-2-oxo-6-thia-1,8-diazatricyclo[7.3.0.03,7]dodeca-3(7),4,8-triene-5-carboxamide