Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -39.574% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1
b O=C(NCC1CCN(Cc2ccc(F)cc2)CC1)C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1
c CN(C)CCCNC(=S)Nc1ccc(-c2ccccc2)cc1
d COC(c1ccccc1)(c1ccccc1)C(Oc1nccc(C)n1)C(=O)O
e O=C(NCCCn1ccnc1)C1CCN(S(=O)(=O)c2ccc(F)cc2)CC1
Answer: b. O=C(NCC1CCN(Cc2ccc(F)cc2)CC1)C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCC1CCN(Cc2ccc(F)cc2)CC1)C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1
O=C(NCC1CCN(Cc2ccc(F)cc2)CC1)C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1
N-[[1-[(4-fluorophenyl)methyl]piperidin-4-yl]methyl]-1-(7,8,9,10-tetrahydro-6H-purino[9,8-a]azepin-4-yl)piperidine-3-carboxamide