Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 15.417% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. Fc1cccc(F)c1/C=N/Nc1ccccn1
b. CCOc1ccc(N2CC(C(=O)NCc3ccccn3)CC2=O)cc1
c. COC(=O)c1cc(OC)c(OC)cc1N1C(=O)CC(C)(C)CC1=O
d. COc1ccc(N2CCN(CC(O)COC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1.O=C(O)C(=O)O
Answer: c. COC(=O)c1cc(OC)c(OC)cc1N1C(=O)CC(C)(C)CC1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cc(OC)c(OC)cc1N1C(=O)CC(C)(C)CC1=O
COC(=O)c1cc(OC)c(OC)cc1N1C(=O)CC(C)(C)CC1=O
methyl 2-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)-4,5-dimethoxybenzoate