Problem statement: Answer the multiple-choice question.
Question: Which compound has a 8.547% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccc(NC(=O)c2cc(S(=O)(=O)N3CCOCC3)cs2)cc1
[b] COC(=O)c1c(=O)n(O)c2ccc(OC)cc2[n+]1[O-]
[c] Cc1nc(-c2nc(CC(=O)NNC(=O)c3ccc(Cl)cc3)cs2)cs1
[d] N#Cc1c(-c2ccccc2)nc(SCc2nc(N)nc(N3CCCCC3)n2)[nH]c1=O
[e] CCN(CC)S(=O)(=O)c1ccc(C)c(NC(=O)COC(=O)CNC(=O)c2ccc(C(C)(C)C)cc2)c1
Answer: a. COc1ccc(NC(=O)c2cc(S(=O)(=O)N3CCOCC3)cs2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)c2cc(S(=O)(=O)N3CCOCC3)cs2)cc1
COc1ccc(NC(=O)c2cc(S(=O)(=O)N3CCOCC3)cs2)cc1
N-(4-methoxyphenyl)-4-morpholin-4-ylsulfonylthiophene-2-carboxamide