Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -11.893% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
[a] COc1ccccc1CNC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(Cl)cc1
[b] CCOc1cc(NC(=S)Nc2ccccc2)c(OCC)cc1NC(=O)c1ccc(OC)cc1
[c] COc1c(Cl)cc(Cl)cc1CNCCO.Cl
Answer: a. COc1ccccc1CNC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1CNC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(Cl)cc1
COc1ccccc1CNC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(Cl)cc1
(2S)-1-(4-chlorophenyl)sulfonyl-N-[(2-methoxyphenyl)methyl]pyrrolidine-2-carboxamide