Problem statement: Answer the MCQ question.
Question: Which drug has a -54.588% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1ccnc(NC2(C(F)(F)F)N=C(c3ccccc3)NC2=O)c1
b. Cc1ccc(/C=c2\sc3n(c2=O)CN(c2ccc(Br)cc2)CN=3)o1
c. CCn1c(SCC(=O)N2c3ccccc3CC2C)nnc1-c1ccco1
d. Cc1cccc(C)c1OCC(O)Cn1ccnc1C
e. CCN1CCN(c2ncnc3scc(-c4ccc(OC)cc4)c23)CC1
Answer: e. CCN1CCN(c2ncnc3scc(-c4ccc(OC)cc4)c23)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1CCN(c2ncnc3scc(-c4ccc(OC)cc4)c23)CC1
CCN1CCN(c2ncnc3scc(-c4ccc(OC)cc4)c23)CC1
4-(4-ethylpiperazin-1-yl)-5-(4-methoxyphenyl)thieno[2,3-d]pyrimidine