Problem statement: Answer the multiple choice question.
Query: Which compound exhibits a -16.110% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CN(C)c1ccc(S(=O)(=O)NCC(=O)OCC(=O)c2ccc[nH]2)cc1[N+](=O)[O-]
b) Cc1cccc(Nc2nnc(SCC(=O)NC(=O)CN3CCCC3=O)s2)c1
c) O=C(NN=C1CCCCC1)c1ccccc1OCc1ccc(F)cc1
d) COc1ccc(C2C(C#N)=C(/N=C/N3CCN(C)CC3)OC3=C2C(=O)CC(C)(C)C3)cc1
e) COc1cccc(-c2nnc(-c3ccc(C)o3)o2)c1
Answer: d. COc1ccc(C2C(C#N)=C(/N=C/N3CCN(C)CC3)OC3=C2C(=O)CC(C)(C)C3)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2C(C#N)=C(/N=C/N3CCN(C)CC3)OC3=C2C(=O)CC(C)(C)C3)cc1
COc1ccc(C2C(C#N)=C(/N=C/N3CCN(C)CC3)OC3=C2C(=O)CC(C)(C)C3)cc1
4-(4-methoxyphenyl)-7,7-dimethyl-2-[(E)-(4-methylpiperazin-1-yl)methylideneamino]-5-oxo-6,8-dihydro-4H-chromene-3-carbonitrile