Problem statement: Answer the MCQ question.
Query: Which compound has a -6.577% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a NC(=O)c1c(NC(=O)CN2CCCC2)sc2c1CCCC2
b CC1=C(C#N)C(c2cccnc2)C2=C(N1)c1ccccc1C2=O
c COc1ccc(CN2C(=O)[C@@H]3Cc4c([nH]c5ccccc45)C(C)(C)N3C2=O)cc1
d COc1ccc(OC)c2c1cc(C(=O)N[C@@H](Cc1ccccc1)C(=O)O)n2C
e COc1cccc(OC)c1C(=O)Nn1c(-c2cccs2)nc2ccccc2c1=O
Answer: e. COc1cccc(OC)c1C(=O)Nn1c(-c2cccs2)nc2ccccc2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(OC)c1C(=O)Nn1c(-c2cccs2)nc2ccccc2c1=O
COc1cccc(OC)c1C(=O)Nn1c(-c2cccs2)nc2ccccc2c1=O
2,6-dimethoxy-N-[4-oxo-2-(thiophen-2-yl)quinazolin-3-yl]benzamide