Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -33.900% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CC(C1CC2CCC1C2)N1CC(O)=C(c2nc3ccccc3[nH]2)C1=N
b COC(=O)CSc1nc(C2CC2)cc(C(F)(F)F)c1C#N
c Cc1cc(C(=O)NNC(=O)CN2C(=O)NC3(CCCCC3)C2=O)c(C)o1
d Cc1ccccc1NC(=O)c1ccc(C)c(S(=O)(=O)N2CCN(C)CC2)c1
e O=C(c1ccccc1Oc1ccccc1)N1CCN(c2ccc(F)cc2)CC1
Answer: e. O=C(c1ccccc1Oc1ccccc1)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccccc1Oc1ccccc1)N1CCN(c2ccc(F)cc2)CC1
O=C(c1ccccc1Oc1ccccc1)N1CCN(c2ccc(F)cc2)CC1
[4-(4-fluorophenyl)piperazin-1-yl]-(2-phenoxyphenyl)methanone