Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -30.450% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CC(=Nc1ccc(C)c(C)c1)C1=C(O)CSC1=O
b: CN(C)CCN(C(=O)c1cccc(Cl)c1)c1nc2c(Cl)cccc2s1.Cl
c: CCOC(=O)[C@@H]1[C@H]2COc3ccccc3[C@H]2N2C(=O)N(c3ccc(C)cc3)C(=O)[C@]12C
d: N#CCC1c2ccccc2CCN1C(=O)Nc1ccc(C(F)(F)F)cc1
e: CCOc1cc(S(=O)(=O)n2nc(C)cc2C)ccc1F
Answer: d. N#CCC1c2ccccc2CCN1C(=O)Nc1ccc(C(F)(F)F)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#CCC1c2ccccc2CCN1C(=O)Nc1ccc(C(F)(F)F)cc1
N#CCC1c2ccccc2CCN1C(=O)Nc1ccc(C(F)(F)F)cc1
1-(cyanomethyl)-N-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxamide