Problem statement: Answer the MCQ question.
Question: Which drug has a -25.141% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCOC(=O)c1[nH]c(C)c(C(=O)NCCN2CCOCC2)c1C
b. COc1nccc(C(F)(F)F)c1C(=O)NC(=O)Nc1ccccc1
c. CCCCn1c(N)c(N(CCOC)C(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)c(=O)[nH]c1=O
d. O=C(Nc1nc2ccccc2n1Cc1ccccc1)c1ccc(COc2ccccc2[N+](=O)[O-])o1
e. CC(=NCC1CCCO1)c1c(O)n(C)c(=O)n(C)c1=O
Answer: c. CCCCn1c(N)c(N(CCOC)C(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCn1c(N)c(N(CCOC)C(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)c(=O)[nH]c1=O
CCCCn1c(N)c(N(CCOC)C(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)c(=O)[nH]c1=O
N-(6-amino-1-butyl-2,4-dioxopyrimidin-5-yl)-N-(2-methoxyethyl)-4-piperidin-1-ylsulfonylbenzamide