Problem statement: Answer the multiple-choice question.
Query: Which drug has a -30.253% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] Cc1c(C(=O)NNS(=O)(=O)c2ccccc2)sc(=S)n1C
[b] CCN(CC)S(=O)(=O)c1cc(NC(=O)COC(=O)C2CCC2)ccc1C
[c] COCCn1c(C)cc(C(=O)COC(=O)/C=C/c2c(C)nn(C3CCS(=O)(=O)C3)c2Cl)c1C
[d] CC(C)C(C(=O)NC(C)(C)C)N(CCN1CCOCC1)C(=O)CNS(=O)(=O)c1ccccc1
[e] O=C(CCS(=O)(=O)c1cccc2nsnc12)N1CCN(c2ccccc2F)CC1
Answer: e. O=C(CCS(=O)(=O)c1cccc2nsnc12)N1CCN(c2ccccc2F)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCS(=O)(=O)c1cccc2nsnc12)N1CCN(c2ccccc2F)CC1
O=C(CCS(=O)(=O)c1cccc2nsnc12)N1CCN(c2ccccc2F)CC1
3-(2,1,3-benzothiadiazol-4-ylsulfonyl)-1-[4-(2-fluorophenyl)piperazin-1-yl]propan-1-one