Problem statement: Answer the multiple choice question.
Query: Which compound has a -18.248% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCCn1c(C(O)c2ccc(C)cc2)nc2ccccc21
b) CCN(CC)CCO
c) CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)c1nc[nH]c1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1
d) COc1cc(C(=O)NC2CCN(Cc3nnnn3Cc3ccc(F)cc3)CC2)cc(OC)c1OC
e) Cc1nnc(N(C(=O)c2cnccn2)c2ccccc2)s1
Answer: c. CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)c1nc[nH]c1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)c1nc[nH]c1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1
CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)c1nc[nH]c1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1
tert-butyl 4-[4-[[(2S)-1-[(2-methylpropan-2-yl)oxy]-1-oxo-3-phenylpropan-2-yl]carbamoyl]-1H-imidazole-5-carbonyl]piperazine-1-carboxylate