Problem statement: Answer the MCQ question.
Question: Which drug has a -21.101% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) CN1CCN(CC(=O)N2c3ccccc3C(C)(c3ccc(Cl)cc3)CC2(C)C)CC1
b) S=c1[nH]nc(-c2ccc(Br)cc2)n1-c1ccc2c(c1)OCCO2
c) COCCNC(=O)CCCn1c(=O)c2cc(OC)c(OC)cc2n(CC(=O)c2cccc(OC)c2)c1=O
d) COc1ccc(C)cc1-c1nc2ccccc2c(-c2ccccc2)c1CC(=O)O.Cl
Answer: a. CN1CCN(CC(=O)N2c3ccccc3C(C)(c3ccc(Cl)cc3)CC2(C)C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1CCN(CC(=O)N2c3ccccc3C(C)(c3ccc(Cl)cc3)CC2(C)C)CC1
CN1CCN(CC(=O)N2c3ccccc3C(C)(c3ccc(Cl)cc3)CC2(C)C)CC1
1-[4-(4-chlorophenyl)-2,2,4-trimethyl-3H-quinolin-1-yl]-2-(4-methylpiperazin-1-yl)ethanone