Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -59.392% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) Cc1cccc2cc(C3CC(c4ccco4)=NN3S(C)(=O)=O)c(Cl)nc12
b.) CCN(CC)CCNC(=O)c1cn(CC)c2ccc(S(=O)(=O)N3CCc4ccccc4C3)cc2c1=O
c.) CC(C)n1cc(C(=O)NC2CC(C)(C)Cc3c2cnn3-c2ccccc2)cn1
d.) COCCNC(=O)c1ccc(CN2CCC(Cc3ccccc3)CC2)cc1
e.) Cc1ccc(C2=NN(CC(=O)NCc3ccccn3)C(=O)CC2)cc1
Answer: b. CCN(CC)CCNC(=O)c1cn(CC)c2ccc(S(=O)(=O)N3CCc4ccccc4C3)cc2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(CC)CCNC(=O)c1cn(CC)c2ccc(S(=O)(=O)N3CCc4ccccc4C3)cc2c1=O
CCN(CC)CCNC(=O)c1cn(CC)c2ccc(S(=O)(=O)N3CCc4ccccc4C3)cc2c1=O
N-[2-(diethylamino)ethyl]-6-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)-1-ethyl-4-oxoquinoline-3-carboxamide