Task: Answer the multiple choice question.
Query: Which drug has a -10.281% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a or b without using any additional words.
Options:
a: COc1cc(NS(=O)(=O)c2ccc(NC(=O)C34CC5CC(CC(C5)C3)C4)cc2)ncn1
b: COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(C4CCCCC4)C(=O)[C@@H]32)cc1
Answer: b. COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(C4CCCCC4)C(=O)[C@@H]32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(C4CCCCC4)C(=O)[C@@H]32)cc1
COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(C4CCCCC4)C(=O)[C@@H]32)cc1
(4aS,8R,8aS)-2-cyclohexyl-N-[(4-methoxyphenyl)methyl]-1-oxo-3,4,4a,7,8,8a-hexahydroisoquinoline-8-carboxamide