Problem statement: Answer the multiple choice question.
Question: Which drug has a 12.230% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCOC(=O)Cc1nnc(NCc2ccccc2)c2ccccc12
b) O=C(NCc1cccnc1)c1ccc(COc2ccc(Cl)cc2)cc1
c) CCCn1nc2cc(C(=O)NCc3ccc4c(c3)OCO4)ccc2c1OCC
d) Cc1ccc(CNC(=O)c2ccc(N3CCC4(CC3)CC(c3cccc(Br)c3)=NO4)c(NC(=O)c3cccc(C)c3)c2)cc1
e) CSC(=NC#N)N1CCN(c2c(C)cccc2C)CC1
Answer: d. Cc1ccc(CNC(=O)c2ccc(N3CCC4(CC3)CC(c3cccc(Br)c3)=NO4)c(NC(=O)c3cccc(C)c3)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(CNC(=O)c2ccc(N3CCC4(CC3)CC(c3cccc(Br)c3)=NO4)c(NC(=O)c3cccc(C)c3)c2)cc1
Cc1ccc(CNC(=O)c2ccc(N3CCC4(CC3)CC(c3cccc(Br)c3)=NO4)c(NC(=O)c3cccc(C)c3)c2)cc1
4-[3-(3-bromophenyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl]-3-[(3-methylbenzoyl)amino]-N-[(4-methylphenyl)methyl]benzamide