Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -23.138% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a. COc1ccccc1/C=C1\SC(=O)N(CCC(=O)NNC(=O)c2ccccc2Cl)C1=O
b. CCCC1O[C@@H]2CC3C4CCC5=CC(=O)C=C[C@]5(C)C4C(OC(C)=O)C[C@]3(C)[C@]2(C(=O)COC(C)=O)O1
c. CCCCN(CC(=O)NC1CCCC1)C(=O)C(=O)Nc1ccc2c(c1)OCCO2
Answer: b. CCCC1O[C@@H]2CC3C4CCC5=CC(=O)C=C[C@]5(C)C4C(OC(C)=O)C[C@]3(C)[C@]2(C(=O)COC(C)=O)O1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCC1O[C@@H]2CC3C4CCC5=CC(=O)C=C[C@]5(C)C4C(OC(C)=O)C[C@]3(C)[C@]2(C(=O)COC(C)=O)O1
CCCC1O[C@@H]2CC3C4CCC5=CC(=O)C=C[C@]5(C)C4C(OC(C)=O)C[C@]3(C)[C@]2(C(=O)COC(C)=O)O1
[2-[(4R,8S,9S,13R)-11-acetyloxy-9,13-dimethyl-16-oxo-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] acetate