Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 8.016% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. O=C(NCCCN1CCOCC1)c1ccc(Sc2ccccc2Cl)c([N+](=O)[O-])c1
b. COC(=O)c1ccc(NC(=O)Nc2ccccc2F)cc1
c. C[C@]12CCC3C(CC[C@H]4CC(O)CC[C@]34C)C1CC/C2=N/O
d. Cc1ccc(Nc2c(-c3ccc(N4CCOCC4)cc3)nc3ncccn23)cc1
e. Cc1ccc2c(cnn2C(=O)CCC(=O)NCc2cccc(Br)c2)c1
Answer: d. Cc1ccc(Nc2c(-c3ccc(N4CCOCC4)cc3)nc3ncccn23)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(Nc2c(-c3ccc(N4CCOCC4)cc3)nc3ncccn23)cc1
Cc1ccc(Nc2c(-c3ccc(N4CCOCC4)cc3)nc3ncccn23)cc1
N-(4-methylphenyl)-2-(4-morpholin-4-ylphenyl)imidazo[1,2-a]pyrimidin-3-amine