Problem statement: Answer the multiple-choice question.
Question: Which drug has a -76.583% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1cc(C(O)c2nc3ccccc3s2)cc(OC)c1OC
b: C#CCOCCOCCOCCNc1nc(N2CCN(C(=O)[C@H](CCCCN)n3cc(C(N)CO)nn3)CC2)nc(N2CCN(C(=O)[C@H](CCCCN)n3cc(C(N)COC(=O)C(F)(F)F)nn3)CC2)n1.Cl
c: COc1ccc(CNC(=O)C(c2ccco2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2OC)cc1
d: COc1ccc(CNc2nc(SCc3cc(=O)n4cc(Cl)ccc4n3)nc3ccccc23)cc1
e: CCN1CCCC1CNc1ncnc2c1[nH]c1ccc(F)cc12
Answer: e. CCN1CCCC1CNc1ncnc2c1[nH]c1ccc(F)cc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1CCCC1CNc1ncnc2c1[nH]c1ccc(F)cc12
CCN1CCCC1CNc1ncnc2c1[nH]c1ccc(F)cc12
N-[(1-ethylpyrrolidin-2-yl)methyl]-8-fluoro-5H-pyrimido[5,4-b]indol-4-amine