Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -2.162% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a) O=C(Nc1nnc(COc2ccc(Br)cc2)s1)c1ccco1
b) O=C(CSC(=S)N1CCCCC1)c1c(F)cccc1F
c) COc1ccc(-c2ccc(O[C@@H]3OC(C)(C)[C@H](OC)[C@@H](O)[C@H]3O)cc2C(=O)NCCc2ccccc2)cc1
d) COCCNC(=O)CCCn1c(=O)c2cc(OC)c(OC)cc2n(CC(=O)NCCC2=CCCCC2)c1=O
Answer: d. COCCNC(=O)CCCn1c(=O)c2cc(OC)c(OC)cc2n(CC(=O)NCCC2=CCCCC2)c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCNC(=O)CCCn1c(=O)c2cc(OC)c(OC)cc2n(CC(=O)NCCC2=CCCCC2)c1=O
COCCNC(=O)CCCn1c(=O)c2cc(OC)c(OC)cc2n(CC(=O)NCCC2=CCCCC2)c1=O
4-[1-[2-[2-(cyclohexen-1-yl)ethylamino]-2-oxoethyl]-6,7-dimethoxy-2,4-dioxoquinazolin-3-yl]-N-(2-methoxyethyl)butanamide