Problem statement: Answer the MCQ question.
Query: Which compound has a 9.689% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CCOC(=O)Cc1csc(NC(=O)COc2cc(C)cc(C)c2)n1
[b] COc1cccc(C(C(=O)NCC2CCCO2)N(C(=O)Cn2nnc3ccccc32)c2ccc(NC(C)=O)cc2)c1
[c] COc1ccc(-c2nsc(C(=O)N(c3ccc(F)cc3)C(C(=O)NC3CCCC3)c3ccc(OC)cc3)c2N)cc1
[d] O=C(O)CSc1nc2c(c(C(F)(F)F)n1)CCCC2
[e] Cc1cc(NC(=O)Nc2ccccc2[N+](=O)[O-])n(C)n1
Answer: c. COc1ccc(-c2nsc(C(=O)N(c3ccc(F)cc3)C(C(=O)NC3CCCC3)c3ccc(OC)cc3)c2N)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2nsc(C(=O)N(c3ccc(F)cc3)C(C(=O)NC3CCCC3)c3ccc(OC)cc3)c2N)cc1
COc1ccc(-c2nsc(C(=O)N(c3ccc(F)cc3)C(C(=O)NC3CCCC3)c3ccc(OC)cc3)c2N)cc1
4-amino-N-[2-(cyclopentylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-(4-fluorophenyl)-3-(4-methoxyphenyl)-1,2-thiazole-5-carboxamide