Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a -11.446% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1cc(O)c(-c2cc(C(=O)NCc3ccc4c(c3)OCO4)[nH]n2)cc1C
(b) COc1ccc(Cn2c(-c3ccc(OC)cc3)nc3c(c(=O)c4ccccc4n3C)c2=O)cc1
(c) COc1ccc(C(=O)NCc2csc(C)n2)cc1OC1CCN(C(C)=O)CC1
(d) COc1ccc(Br)cc1CN1C(=O)NC2(CCCCCC2)C1=O
(e) O=C(NCC(=O)N1CCN(C(=O)c2ccccc2)CC1)c1ccccc1
Answer: b. COc1ccc(Cn2c(-c3ccc(OC)cc3)nc3c(c(=O)c4ccccc4n3C)c2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(Cn2c(-c3ccc(OC)cc3)nc3c(c(=O)c4ccccc4n3C)c2=O)cc1
COc1ccc(Cn2c(-c3ccc(OC)cc3)nc3c(c(=O)c4ccccc4n3C)c2=O)cc1
2-(4-methoxyphenyl)-3-[(4-methoxyphenyl)methyl]-10-methylpyrimido[4,5-b]quinoline-4,5-dione