Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -0.990% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccc(-n2c(-c3ccc(Br)cc3)c[n+]3c2CCC3)cc1.[Br-]
b: O=C(Nc1ccc(OC(F)(F)F)cc1)Oc1ccccc1N1CCOCC1
c: C/C(Cn1cnc([N+](=O)[O-])n1)=N/NC(=O)COc1c(Cl)cc(Cl)cc1Cl
d: CC(=O)N1CCOc2ccc(S(=O)(=O)N3CCC(C(=O)Nc4cc(C)ccc4C)CC3)cc21
e: CC1(C)Cc2c(sc(NC(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)c2C(N)=O)C(C)(C)N1
Answer: e. CC1(C)Cc2c(sc(NC(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)c2C(N)=O)C(C)(C)N1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1(C)Cc2c(sc(NC(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)c2C(N)=O)C(C)(C)N1
CC1(C)Cc2c(sc(NC(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)c2C(N)=O)C(C)(C)N1
2-[[4-(azepan-1-ylsulfonyl)benzoyl]amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxamide