Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -10.233% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1ccc(S(=O)(=O)CCC(=O)OCC(=O)c2cc(C)ccc2C)cc1
(b) C=CCN1CCN(c2ccncc2S(=O)(=O)N2CCCCC2)CC1
(c) CCC(=NCc1ccco1)c1c(O)n(-c2ccccc2C)c(=O)[nH]c1=O
(d) Cc1cccc(OCc2nnc(SCc3cc(=O)n4cc(Br)ccc4n3)o2)c1
(e) CC(C)C[C@H](NC(=O)c1nc[nH]c1C(=O)N1CCN(c2ccccc2)CC1)C(=O)OCc1ccccc1
Answer: e. CC(C)C[C@H](NC(=O)c1nc[nH]c1C(=O)N1CCN(c2ccccc2)CC1)C(=O)OCc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)C[C@H](NC(=O)c1nc[nH]c1C(=O)N1CCN(c2ccccc2)CC1)C(=O)OCc1ccccc1
CC(C)C[C@H](NC(=O)c1nc[nH]c1C(=O)N1CCN(c2ccccc2)CC1)C(=O)OCc1ccccc1
benzyl (2S)-4-methyl-2-[[5-(4-phenylpiperazine-1-carbonyl)-1H-imidazole-4-carbonyl]amino]pentanoate