Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -23.596% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COCCn1c(SCC(=O)N2CCCC2)nnc1-c1ccoc1C
b.) CCCc1nc(C)c(-c2ccc(OC)c(OC)c2)c(=O)[nH]1
c.) COc1ccc(C)cc1N(C(=O)COc1cccc(F)c1)c1nc2ccccc2s1
d.) c1ccc(Cc2c[nH]c3ccccc23)cc1
e.) CCOc1ccc(Br)cc1S(=O)(=O)Nc1cccc(S(=O)(=O)N(C)C)c1
Answer: e. CCOc1ccc(Br)cc1S(=O)(=O)Nc1cccc(S(=O)(=O)N(C)C)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(Br)cc1S(=O)(=O)Nc1cccc(S(=O)(=O)N(C)C)c1
CCOc1ccc(Br)cc1S(=O)(=O)Nc1cccc(S(=O)(=O)N(C)C)c1
5-bromo-N-[3-(dimethylsulfamoyl)phenyl]-2-ethoxybenzenesulfonamide