Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -2.849% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CCOC(=O)c1ccc(COC(=O)CCc2nc(-c3ccccc3)c(-c3ccccc3)o2)cc1
[b] CN(C)CCNC(=S)Nc1ccc(Cl)cc1
[c] COc1cccc(NC(=S)N2CCCC2c2ccc(OC)c(OC)c2)c1
[d] CC(CC(=O)N1CCc2ccccc21)S(=O)(=O)c1ccc2c(c1)NC(=O)CO2
[e] COC(=O)C1(C)NC(c2ccc(C)cc2)C2C(=O)N(c3ccc(F)cc3)C(=O)C21
Answer: e. COC(=O)C1(C)NC(c2ccc(C)cc2)C2C(=O)N(c3ccc(F)cc3)C(=O)C21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1(C)NC(c2ccc(C)cc2)C2C(=O)N(c3ccc(F)cc3)C(=O)C21
COC(=O)C1(C)NC(c2ccc(C)cc2)C2C(=O)N(c3ccc(F)cc3)C(=O)C21
methyl 5-(4-fluorophenyl)-3-methyl-1-(4-methylphenyl)-4,6-dioxo-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylate