Problem statement: Answer the MCQ question.
Question: Which compound has a -43.396% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a CC(C)[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NC1CCCCC1
b COc1ccc(/C(C)=N/Nc2ccc(F)cc2F)c(O)c1
c CC1(C)CC(=O)/C(=C(\O)c2ccccc2)C(=NCCc2ccccc2)C1
d CC(=O)CC1OC(=O)C(Br)=C1NCc1ccccc1
e CNS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)sc2c1
Answer: a. CC(C)[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NC1CCCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NC1CCCCC1
CC(C)[C@H](NC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NC1CCCCC1
(3S)-N-[(2S)-1-(cyclohexylamino)-3-methyl-1-oxobutan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide