Problem statement: Answer the multiple-choice question.
Question: Which compound has a -16.372% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCc1ccc(-c2csc(NC(=O)C3=COCCO3)n2)cc1
(b) CCN(C(=O)CSc1nc(-c2cccs2)nc2ccccc12)C1CCS(=O)(=O)C1
(c) O=C1CC(c2ccccc2)CCc2sccc2N1
(d) COC(=O)CCCCCN1C(=O)NC(C2CC2)C(C(=O)OCc2ccccc2)=C1C
(e) Cc1ccc(C(=O)c2sc(Nc3ccccc3)c(C#N)c2N)cc1
Answer: d. COC(=O)CCCCCN1C(=O)NC(C2CC2)C(C(=O)OCc2ccccc2)=C1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)CCCCCN1C(=O)NC(C2CC2)C(C(=O)OCc2ccccc2)=C1C
COC(=O)CCCCCN1C(=O)NC(C2CC2)C(C(=O)OCc2ccccc2)=C1C
benzyl 6-cyclopropyl-3-(6-methoxy-6-oxohexyl)-4-methyl-2-oxo-1,6-dihydropyrimidine-5-carboxylate