Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 1.823% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a. Cc1nc(N2CCCCC2)nc(N2CCCCC2)c1C=O
b. COc1ccc(C(=O)N2CC3(CC(c4cccc(NC(=O)CC(c5ccccc5)c5ccccc5)c4)=NO3)C[C@H]2C(N)=O)cc1
c. Cc1nc2ccccc2n1CCOc1ccc([N+](=O)[O-])cc1
Answer: b. COc1ccc(C(=O)N2CC3(CC(c4cccc(NC(=O)CC(c5ccccc5)c5ccccc5)c4)=NO3)C[C@H]2C(N)=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)N2CC3(CC(c4cccc(NC(=O)CC(c5ccccc5)c5ccccc5)c4)=NO3)C[C@H]2C(N)=O)cc1
COc1ccc(C(=O)N2CC3(CC(c4cccc(NC(=O)CC(c5ccccc5)c5ccccc5)c4)=NO3)C[C@H]2C(N)=O)cc1
(8S)-3-[3-(3,3-diphenylpropanoylamino)phenyl]-7-(4-methoxybenzoyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide