Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -1.141% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1ccc(C2=NNC(c3ccco3)=Nc3ccc(F)cc32)cc1
b.) O=C(COc1ccc(Br)cc1)c1ccc2c(c1)CCCC2
c.) O=C(O)c1ccc(Cl)c(S(=O)(=O)N(Cc2ccccc2)c2ccccc2Cl)c1
d.) CC(NC(=O)Cc1ccc(S(=O)(=O)N2CCOCC2)s1)c1ccc(Cl)c(Cl)c1
e.) COc1cc(OC)cc(C(=O)N[C@H](C(=O)NCCc2ccc(S(N)(=O)=O)cc2)C(C)C)c1
Answer: b. O=C(COc1ccc(Br)cc1)c1ccc2c(c1)CCCC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COc1ccc(Br)cc1)c1ccc2c(c1)CCCC2
O=C(COc1ccc(Br)cc1)c1ccc2c(c1)CCCC2
2-(4-bromophenoxy)-1-(5,6,7,8-tetrahydronaphthalen-2-yl)ethanone