Task: Answer the multiple-choice question.
Query: Which compound exhibits a -24.746% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a. COc1cc(NC(=S)NN2CCN(C)CC2)cc(OC)c1OC
b. COC(=O)CC1=C(C(=O)OC)C(c2ccc3c(c2Cl)OCO3)C(C#N)=C(N)O1
c. O=C(Nc1ccc2ccccc2n1)Nc1ccccc1F
Answer: b. COC(=O)CC1=C(C(=O)OC)C(c2ccc3c(c2Cl)OCO3)C(C#N)=C(N)O1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)CC1=C(C(=O)OC)C(c2ccc3c(c2Cl)OCO3)C(C#N)=C(N)O1
COC(=O)CC1=C(C(=O)OC)C(c2ccc3c(c2Cl)OCO3)C(C#N)=C(N)O1
methyl 6-amino-4-(4-chloro-1,3-benzodioxol-5-yl)-5-cyano-2-(2-methoxy-2-oxoethyl)-4H-pyran-3-carboxylate