Problem statement: Answer the multiple-choice question.
Question: Which compound has a 17.351% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCCCCOc1ccc(NC(=O)C(=O)NCCCn2ccnc2)cc1
b) Cc1ccc(NC(=O)COC(=O)CN2C(=O)NC(C)(C)C2=O)cc1S(=O)(=O)N1CCOCC1
c) Cc1ccccc1OCCn1cnc2c(N)ncnc21
d) CCCOC(=O)c1ccc(NC(=O)c2c(Cl)ccc(Cl)c2OC)cc1
e) CC(NC(=O)c1ccccc1F)c1ccccc1
Answer: b. Cc1ccc(NC(=O)COC(=O)CN2C(=O)NC(C)(C)C2=O)cc1S(=O)(=O)N1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(NC(=O)COC(=O)CN2C(=O)NC(C)(C)C2=O)cc1S(=O)(=O)N1CCOCC1
Cc1ccc(NC(=O)COC(=O)CN2C(=O)NC(C)(C)C2=O)cc1S(=O)(=O)N1CCOCC1
[2-(4-methyl-3-morpholin-4-ylsulfonylanilino)-2-oxoethyl] 2-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)acetate