Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -28.292% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc(/C=C2\C(=O)N(c3c(Cl)cc(Cl)cc3Cl)N=C2NC(=O)c2cccc([N+](=O)[O-])c2)cc1
(b) CCCn1nc(C(=O)N2CCN(S(=O)(=O)c3ccc(C)c(C)c3)CC2)c2ccccc2c1=O
(c) CCN(CC)CCNC(=O)c1ccc2c(=O)n(C3CCCC3)c(=S)[nH]c2c1
(d) COCCn1cc(C(=O)NCc2ccco2)c2c3ccccc3n(C)c2c1=O
(e) COCCN1CCc2c(C)nc3c(-c4ccc(OC)c(OC)c4)cnn3c21
Answer: b. CCCn1nc(C(=O)N2CCN(S(=O)(=O)c3ccc(C)c(C)c3)CC2)c2ccccc2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCn1nc(C(=O)N2CCN(S(=O)(=O)c3ccc(C)c(C)c3)CC2)c2ccccc2c1=O
CCCn1nc(C(=O)N2CCN(S(=O)(=O)c3ccc(C)c(C)c3)CC2)c2ccccc2c1=O
4-[4-(3,4-dimethylphenyl)sulfonylpiperazine-1-carbonyl]-2-propylphthalazin-1-one