Problem statement: Answer the MCQ question.
Query: Which drug has a -7.523% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1[nH]c2ccccc2c1/C=C/C(=O)c1ccccc1
b) Cc1ccccc1NC(=O)Cc1nnc(SCc2ccc(Cl)c(Cl)c2)n1C
c) CCc1ccccc1NC(=O)C1CCN(C(=O)c2cccs2)CC1
d) O=C(NCCc1cccnc1)C1CCC(=O)N(CCc2cccc(F)c2)C1
e) CCCCC(=O)Nc1c2c(nn1-c1ccc(C)cc1)CS(=O)(=O)C2
Answer: e. CCCCC(=O)Nc1c2c(nn1-c1ccc(C)cc1)CS(=O)(=O)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCC(=O)Nc1c2c(nn1-c1ccc(C)cc1)CS(=O)(=O)C2
CCCCC(=O)Nc1c2c(nn1-c1ccc(C)cc1)CS(=O)(=O)C2
N-[2-(4-methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]pentanamide