Problem statement: Answer the MCQ question.
Query: Which compound has a -8.415% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. C/C(=C1/SC(N2CCOCC2)=NC1=O)c1ccc(Br)cc1
b. CSCCC(NS(=O)(=O)c1cccc(C(F)(F)F)c1)C(=O)Nc1ccccc1N1CCCC1
c. O=C(c1cc(F)ccc1F)C1CCCN(C(=O)c2ccc3nccnc3c2)C1
d. COc1ccc(CN(C(=O)CCC(=O)Nc2cc(C)on2)C(C(=O)NC(C)(C)C)c2cccc(OC)c2OC)cc1
e. CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc(-c4cnc(C5CC5)o4)cc3)CC2)cc1
Answer: b. CSCCC(NS(=O)(=O)c1cccc(C(F)(F)F)c1)C(=O)Nc1ccccc1N1CCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CSCCC(NS(=O)(=O)c1cccc(C(F)(F)F)c1)C(=O)Nc1ccccc1N1CCCC1
CSCCC(NS(=O)(=O)c1cccc(C(F)(F)F)c1)C(=O)Nc1ccccc1N1CCCC1
4-methylsulfanyl-N-(2-pyrrolidin-1-ylphenyl)-2-[[3-(trifluoromethyl)phenyl]sulfonylamino]butanamide