Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -9.511% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: Clc1cccc(Nc2nc(-c3ccncc3)nc3ccccc23)c1
b: O=C(CCN1CCN(c2ccccc2)CC1)Nc1ccccc1F
c: COc1ccc(N2CCN(C(=O)c3ccc(CNS(=O)(=O)c4ccc(C)cc4)cc3)CC2)cc1
d: COc1ccccc1CCNC(=O)C(=O)NCC1OCCCN1S(=O)(=O)c1cc(C)ccc1C
e: O=C(c1cccc(S(=O)(=O)N2CCN(c3ccccc3)CC2)c1)N1CCCCCCC1
Answer: d. COc1ccccc1CCNC(=O)C(=O)NCC1OCCCN1S(=O)(=O)c1cc(C)ccc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1CCNC(=O)C(=O)NCC1OCCCN1S(=O)(=O)c1cc(C)ccc1C
COc1ccccc1CCNC(=O)C(=O)NCC1OCCCN1S(=O)(=O)c1cc(C)ccc1C
N'-[[3-(2,5-dimethylphenyl)sulfonyl-1,3-oxazinan-2-yl]methyl]-N-[2-(2-methoxyphenyl)ethyl]oxamide