Problem statement: Answer the multiple-choice question.
Question: Which drug has a -43.679% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) COc1ccc(C2/C=C\CN(C(=O)c3ccc(C)cc3)CC(=O)N2Cc2ccc(F)cc2)cc1
b) CCC(=O)c1cn(CC(=O)Nc2cccc(C)c2C)c2ccccc12
c) Cc1onc(-c2c(F)cccc2Cl)c1C(=O)NC1=NCCS1
d) Cn1cc(S(=O)(=O)N2CCN(Cc3ccccc3)CC2)c(=O)n(C)c1=O
Answer: a. COc1ccc(C2/C=C\CN(C(=O)c3ccc(C)cc3)CC(=O)N2Cc2ccc(F)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2/C=C\CN(C(=O)c3ccc(C)cc3)CC(=O)N2Cc2ccc(F)cc2)cc1
COc1ccc(C2/C=C\CN(C(=O)c3ccc(C)cc3)CC(=O)N2Cc2ccc(F)cc2)cc1
(6Z)-4-[(4-fluorophenyl)methyl]-5-(4-methoxyphenyl)-1-(4-methylbenzoyl)-5,8-dihydro-2H-1,4-diazocin-3-one