Problem statement: Answer the MCQ question.
Question: Which compound has a -24.995% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCc1nc(C)cn1S(=O)(=O)c1cc([N+](=O)[O-])ccc1Cl
b. CCc1cc2cc(C)c(C)cc2nc1SCC(=O)Nc1cc(C)on1
c. Cc1c(Cl)c(-c2n[nH]c(=S)n2CC(C)C)nn1C
d. CC1CCc2c(C(=O)N3CCN(S(=O)(=O)c4cccs4)CC3)csc2C1
e. CCn1c(=O)c(=O)[nH]c2cc(C(=O)N3CCN(c4ccccc4F)CC3)ccc21
Answer: d. CC1CCc2c(C(=O)N3CCN(S(=O)(=O)c4cccs4)CC3)csc2C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1CCc2c(C(=O)N3CCN(S(=O)(=O)c4cccs4)CC3)csc2C1
CC1CCc2c(C(=O)N3CCN(S(=O)(=O)c4cccs4)CC3)csc2C1
(6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)-(4-thiophen-2-ylsulfonylpiperazin-1-yl)methanone