Problem statement: Answer the multiple-choice question.
Query: Which drug has a 25.875% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=[N+]([O-])c1c(Nc2cccc(O)c2)cc(Cl)c2nonc12
b) CCOc1ccc(C2NC(=O)NC(c3ccccc3)=C2C(C)=O)cc1OC
c) COc1ccccc1NC(=O)CSc1nnnn1-c1ccc2c(c1)OCO2
d) COC(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1
e) CN(C)c1ccc(N/C(=N\S(=O)(=O)c2cccs2)c2ccccc2)cc1.Cl
Answer: d. COC(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1
COC(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1
methylN-[4-(pyrimidin-2-ylsulfamoyl)phenyl]carbamate