Task: Answer the multiple choice question.
Question: Which compound has a -8.875% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=S1(=O)CCC(n2ncc3c2/C(=C/c2ccccc2)CC3)C1
b.) C/C(=N/NC(=O)c1ccncc1)c1cc2ccc(O)cc2oc1=O
c.) O=C1NC(c2ccccc2)(C(F)(F)F)SC2=CCCCCN12
d.) CC(=O)N1CCN(c2ccc(NC(=O)COc3ccc(Cl)cc3Cl)cc2)CC1
e.) COc1ccc(/C=N/n2cnc3c([nH]c4ccc(Br)cc43)c2=O)cc1CN1CCOCC1
Answer: e. COc1ccc(/C=N/n2cnc3c([nH]c4ccc(Br)cc43)c2=O)cc1CN1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(/C=N/n2cnc3c([nH]c4ccc(Br)cc43)c2=O)cc1CN1CCOCC1
COc1ccc(/C=N/n2cnc3c([nH]c4ccc(Br)cc43)c2=O)cc1CN1CCOCC1
8-bromo-3-[(E)-[4-methoxy-5-(morpholin-4-ylmethyl)phenyl]methylideneamino]-5H-pyrimido[5,4-b]indol-4-one