Problem statement: Answer the multiple-choice question.
Question: Which drug has a -14.125% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) O=C(NCC(=O)N1CCN(C(=O)c2ccccc2)CC1)c1ccccc1
(b) COC(=O)c1ccc(/C=N/OCC(=O)NCc2ccc(F)cc2)cc1
(c) Cc1ccc(S(=O)(=O)N2CCCCC2)cc1C(=O)OC1CCCCC1=O
(d) O=S(=O)(c1ccc(Cl)cc1)N1CCC(O)(CN2CCN(Cc3ccccc3)CC2)CC1
(e) COC(=O)c1sc(C(F)(F)F)c(-c2ccccc2)c1S(=O)(=O)N1CCCC1
Answer: e. COC(=O)c1sc(C(F)(F)F)c(-c2ccccc2)c1S(=O)(=O)N1CCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1sc(C(F)(F)F)c(-c2ccccc2)c1S(=O)(=O)N1CCCC1
COC(=O)c1sc(C(F)(F)F)c(-c2ccccc2)c1S(=O)(=O)N1CCCC1
methyl4-phenyl-3-pyrrolidin-1-ylsulfonyl-5-(trifluoromethyl)thiophene-2-carboxylate