Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -1.059% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COC(=O)C[C@H]1c2cc(F)ccc2S(=O)(=O)N1C(C)C
[b] O=C(COC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccco1)NCc1ccccc1
[c] COC(=O)c1ccccc1NC(=O)CN(c1cc(OC)ccc1OC)S(C)(=O)=O
[d] C/C(=N\NC(=O)c1cccc(O)c1)c1ccc(NC(=O)Cc2ccccc2)cc1
[e] CC(C)c1nnc(NC(=O)C2CCN(c3cnccn3)CC2)s1
Answer: e. CC(C)c1nnc(NC(=O)C2CCN(c3cnccn3)CC2)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)c1nnc(NC(=O)C2CCN(c3cnccn3)CC2)s1
CC(C)c1nnc(NC(=O)C2CCN(c3cnccn3)CC2)s1
N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-1-pyrazin-2-ylpiperidine-4-carboxamide