Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -18.056% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COC(=O)C1=C(c2cccc(OC)c2OC)C[C@@H]2CC[C@H]1N2C(=O)N1CCC(C)CC1
b Cc1ccc(NC(=O)C2CC(=O)N(CCc3ccccc3)C2)c(C)c1
c O=C(CCCN1C(=O)/C(=C/c2cccc(Br)c2)SC1=S)NCCCN1CCOCC1
d O=C(C[n+]1cn(C(F)F)c2ccccc21)c1ccc(OC(F)F)cc1.[Br-]
e O=C(N/N=C/c1coc2ccccc2c1=O)c1cccc([N+](=O)[O-])c1
Answer: c. O=C(CCCN1C(=O)/C(=C/c2cccc(Br)c2)SC1=S)NCCCN1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCCN1C(=O)/C(=C/c2cccc(Br)c2)SC1=S)NCCCN1CCOCC1
O=C(CCCN1C(=O)/C(=C/c2cccc(Br)c2)SC1=S)NCCCN1CCOCC1
4-[(5Z)-5-[(3-bromophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-(3-morpholin-4-ylpropyl)butanamide