Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a 6.760% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O=C1[C@@H]2CSCN2C(=O)CN1Cc1cccc(C(F)(F)F)c1
[b] O=C(Nc1ccnn1C1CCN(C/C=C/c2ccccc2)CC1)c1ccccc1
[c] COc1ccc(Nc2nc3ccccc3n3cnnc23)cc1Cl
[d] O=C(CN1CCCC1)NC(=O)NC1CCCC1
[e] Cc1c(NC(=O)c2cnn3c2NC(c2ccco2)CC3C(F)(F)F)c(=O)n(-c2ccccc2)n1C
Answer: a. O=C1[C@@H]2CSCN2C(=O)CN1Cc1cccc(C(F)(F)F)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1[C@@H]2CSCN2C(=O)CN1Cc1cccc(C(F)(F)F)c1
O=C1[C@@H]2CSCN2C(=O)CN1Cc1cccc(C(F)(F)F)c1
(8aR)-7-[[3-(trifluoromethyl)phenyl]methyl]-1,3,6,8a-tetrahydro-[1,3]thiazolo[3,4-a]pyrazine-5,8-dione