Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -46.405% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1cc(/C=C2/NC(=O)N(Cc3ccccc3F)C2=O)ccc1Oc1ccc([N+](=O)[O-])cn1
[b] CC(C)Cc1cc(C(=O)Nc2sc3c(c2C#N)CCC3)no1
[c] COc1ccccc1CNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1
[d] COc1cc(NC(=O)c2noc(C)c2[N+](=O)[O-])c(OC)cc1Cl
[e] CC(C)(C)NC(=O)NC(=O)CN1CCN(c2ccccc2O)CC1
Answer: c. COc1ccccc1CNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1CNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1
COc1ccccc1CNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1
1-(benzenesulfonyl)-N-[(2-methoxyphenyl)methyl]piperidine-2-carboxamide