Problem statement: Answer the MCQ question.
Question: Which compound has a -41.578% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccccc1CC(=O)Nc1cccc2ccccc12
(b) COc1ccc(S(=O)(=O)NC2CC(C)(C)NC(C)(C)C2)c2ccccc12
(c) CC1CCCCN1C(=O)CN1CCN(S(=O)(=O)c2ccc(Br)cc2Cl)CC1
(d) COc1ccc(S(=O)(=O)NCC(c2cccnc2)N2CCN(c3ccccc3)CC2)cc1C
(e) Cc1cccc(C)c1NC(=O)c1c(C)nn(-c2ccccc2)c1Cl
Answer: c. CC1CCCCN1C(=O)CN1CCN(S(=O)(=O)c2ccc(Br)cc2Cl)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1CCCCN1C(=O)CN1CCN(S(=O)(=O)c2ccc(Br)cc2Cl)CC1
CC1CCCCN1C(=O)CN1CCN(S(=O)(=O)c2ccc(Br)cc2Cl)CC1
2-[4-(4-bromo-2-chlorophenyl)sulfonylpiperazin-1-yl]-1-(2-methylpiperidin-1-yl)ethanone