Problem statement: Answer the multiple-choice question.
Query: Which drug has a 12.978% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CCN(CC)c1nc(OC)nc(-n2nnc(C(C)=O)c2C)n1
[b] O=C(Nc1cccc(C(F)(F)F)c1)NC1CCN(S(=O)(=O)c2ccc(F)cc2)CC1
[c] Fc1ccc(CN(Cc2ccccc2)C(c2cccs2)c2nnnn2C2CCCCC2)cc1
[d] Cc1ccc2c(c1)NC(=O)C(N1CCOCC1)(C(F)(F)F)O2
[e] O=C(COC(=O)c1cc([N+](=O)[O-])ccc1N1CCOCC1)c1ccccc1
Answer: d. Cc1ccc2c(c1)NC(=O)C(N1CCOCC1)(C(F)(F)F)O2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc2c(c1)NC(=O)C(N1CCOCC1)(C(F)(F)F)O2
Cc1ccc2c(c1)NC(=O)C(N1CCOCC1)(C(F)(F)F)O2
6-methyl-2-morpholin-4-yl-2-(trifluoromethyl)-4H-1,4-benzoxazin-3-one