Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -0.969% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C(c1ccc(S(=O)(=O)Nc2ccccc2F)cc1)N1CCC1
b O=C(N/N=C/c1cc(Br)cs1)c1c[nH]c2ccccc12
c COc1ccc(C(=O)COC(=O)c2ccc3c(c2)NC(=O)CS3)c(OC)c1
d CCCCCCCCCNC(=O)[C@H](NC(=O)COc1ccccc1)[C@@H]1NC(C(=O)OC)C(C)(C)S1
e COc1ccc(CCNC(=O)C(C)OC(=O)c2nsc(Cl)c2Cl)cc1OC
Answer: d. CCCCCCCCCNC(=O)[C@H](NC(=O)COc1ccccc1)[C@@H]1NC(C(=O)OC)C(C)(C)S1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCCCCCCNC(=O)[C@H](NC(=O)COc1ccccc1)[C@@H]1NC(C(=O)OC)C(C)(C)S1
CCCCCCCCCNC(=O)[C@H](NC(=O)COc1ccccc1)[C@@H]1NC(C(=O)OC)C(C)(C)S1
methyl (2R)-5,5-dimethyl-2-[(1S)-2-(nonylamino)-2-oxo-1-[(2-phenoxyacetyl)amino]ethyl]-1,3-thiazolidine-4-carboxylate