Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -6.785% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CC(C)CN1C(=O)NC2(CCCc3ccccc32)C1=O
b CCc1cc(Cn2nc(-c3ccccc3)cc2C(=O)NCc2ccc(C)cc2)on1
c Cl.N[C@@H](Cc1c[nH]c2ccccc12)c1nnc(SCc2ccccc2F)o1
d COc1cccc(N2C(=O)Nc3ccc(Br)cc3C2(O)C(=O)NCCCN(C)C)c1
e CN1C(=O)C2(C(C#N)=C(N)N(c3ccc(Cl)cc3)C3=C2C(=O)CC(C)(C)C3)c2ccccc21
Answer: e. CN1C(=O)C2(C(C#N)=C(N)N(c3ccc(Cl)cc3)C3=C2C(=O)CC(C)(C)C3)c2ccccc21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1C(=O)C2(C(C#N)=C(N)N(c3ccc(Cl)cc3)C3=C2C(=O)CC(C)(C)C3)c2ccccc21
CN1C(=O)C2(C(C#N)=C(N)N(c3ccc(Cl)cc3)C3=C2C(=O)CC(C)(C)C3)c2ccccc21
2-amino-1-(4-chlorophenyl)-1',7,7-trimethyl-2',5-dioxospiro[6,8-dihydroquinoline-4,3'-indole]-3-carbonitrile