Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -2.226% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a COc1ccc(S(=O)(=O)Nc2cccnc2)c(C)c1C
b COc1cc2c(cc1OC)C1Cc3c(cnn3-c3ccc(C(F)(F)F)cc3)C(=O)N1CC2
c O=C(Nc1nccs1)c1ccc(COc2ccccc2Br)o1
d COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)c2ccc3c(c2)OCO3)cc1
Answer: b. COc1cc2c(cc1OC)C1Cc3c(cnn3-c3ccc(C(F)(F)F)cc3)C(=O)N1CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C1Cc3c(cnn3-c3ccc(C(F)(F)F)cc3)C(=O)N1CC2
COc1cc2c(cc1OC)C1Cc3c(cnn3-c3ccc(C(F)(F)F)cc3)C(=O)N1CC2
4,5-dimethoxy-15-[4-(trifluoromethyl)phenyl]-10,14,15-triazatetracyclo[8.7.0.02,7.012,16]heptadeca-2,4,6,12(16),13-pentaen-11-one