Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -48.271% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCN1CCN(S(=O)(=O)c2cnc(Cl)c(Br)c2)CC1
(b) CCOC(=O)C1CCN(S(=O)(=O)c2cc(Cl)ccc2OC)CC1
(c) C=CCn1c(SCC(=O)NCc2ccccc2)nnc1-c1cc(Br)ccc1O
(d) Cc1ccc2nc3c(cc2c1)CC1(C(=O)N(C)C(=O)N(C)C1=O)C1CCCCN31
(e) COc1ccccc1CCNC(=O)C(=O)NCC1OCCCN1S(=O)(=O)c1cc(C)ccc1C
Answer: b. CCOC(=O)C1CCN(S(=O)(=O)c2cc(Cl)ccc2OC)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1CCN(S(=O)(=O)c2cc(Cl)ccc2OC)CC1
CCOC(=O)C1CCN(S(=O)(=O)c2cc(Cl)ccc2OC)CC1
ethyl 1-(5-chloro-2-methoxyphenyl)sulfonylpiperidine-4-carboxylate