Problem statement: Answer the MCQ question.
Question: Which drug has a -1.675% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. COc1ccccc1-n1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c(C(=O)Nc2ccc(F)cc2)n1
b. COc1ccc(N2CCOCC2)c(NC(=O)c2cccnc2)c1
c. CC(OC(=O)C1CSC2(c3ccc(F)cc3)CCC(=O)N12)C(=O)NC(N)=O
d. CC(C)(C)n1nc2c(c1NC(=O)COc1ccc3ccccc3c1)CS(=O)C2
Answer: a. COc1ccccc1-n1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c(C(=O)Nc2ccc(F)cc2)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1-n1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c(C(=O)Nc2ccc(F)cc2)n1
COc1ccccc1-n1cc(C2CCN(C(=O)OC(C)(C)C)CC2)c(C(=O)Nc2ccc(F)cc2)n1
tert-butyl 4-[3-[(4-fluorophenyl)carbamoyl]-1-(2-methoxyphenyl)pyrazol-4-yl]piperidine-1-carboxylate