Task: Answer the multiple-choice question.
Question: Which drug exhibits a -63.408% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a CCCCC(=O)OCC(=O)c1[nH]c(C)c(C(C)=O)c1C
b S=C(Nc1ccc(Cl)cc1Cl)NC1CCN(Cc2ccccc2)CC1
c COCCn1ccc2c(OCC(=O)NCc3ccccc3)cccc2c1=O
d COc1ccc(N2CCN(c3ncnc4sc(C(=O)NCC5CCCO5)c(C)c34)CC2)cc1
e CC(=O)Oc1ccccc1C(=O)NC(C)CCc1ccccc1
Answer: d. COc1ccc(N2CCN(c3ncnc4sc(C(=O)NCC5CCCO5)c(C)c34)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(c3ncnc4sc(C(=O)NCC5CCCO5)c(C)c34)CC2)cc1
COc1ccc(N2CCN(c3ncnc4sc(C(=O)NCC5CCCO5)c(C)c34)CC2)cc1
4-[4-(4-methoxyphenyl)piperazin-1-yl]-5-methyl-N-(oxolan-2-ylmethyl)thieno[2,3-d]pyrimidine-6-carboxamide