Problem statement: Answer the multiple-choice question.
Question: Which compound has a 2.519% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) O=C(Nc1ccc(Br)cc1Cl)c1cnccn1
(b) O=C(c1ccccc1NS(=O)(=O)c1ccc(Br)s1)N1CCCC1
(c) COC(=O)N1CCc2c(sc(NC(=O)C3=COCCO3)c2C#N)C1
(d) CC(C)[C@H](NC(=O)NC1CCCc2ccccc21)C(=O)O
(e) N#Cc1nc(-c2ccc(F)cc2)oc1N1CCN(C(=O)c2ccco2)CC1
Answer: c. COC(=O)N1CCc2c(sc(NC(=O)C3=COCCO3)c2C#N)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)N1CCc2c(sc(NC(=O)C3=COCCO3)c2C#N)C1
COC(=O)N1CCc2c(sc(NC(=O)C3=COCCO3)c2C#N)C1
methyl 3-cyano-2-(2,3-dihydro-1,4-dioxine-5-carbonylamino)-5,7-dihydro-4H-thieno[2,3-c]pyridine-6-carboxylate