Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -4.299% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1cccc(C2c3[nH]c4ccccc4c3C[C@H]3C(=O)N(c4ccccc4C(=O)N4CCCC4C(=O)O)C(=O)N23)c1
b CNC(=O)Cn1c(=O)n(C)c2ccccc21
c Cc1ccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2c[nH]c3ccccc23)cc1
d CN(C)/C=N/c1nc(-c2ccc3ccccc3c2)cs1
e CCN(CC)c1ccc(/C=N/N2C(=O)c3ccccc3C2=O)cc1
Answer: a. COc1cccc(C2c3[nH]c4ccccc4c3C[C@H]3C(=O)N(c4ccccc4C(=O)N4CCCC4C(=O)O)C(=O)N23)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(C2c3[nH]c4ccccc4c3C[C@H]3C(=O)N(c4ccccc4C(=O)N4CCCC4C(=O)O)C(=O)N23)c1
COc1cccc(C2c3[nH]c4ccccc4c3C[C@H]3C(=O)N(c4ccccc4C(=O)N4CCCC4C(=O)O)C(=O)N23)c1
1-[2-[(15S)-10-(3-methoxyphenyl)-12,14-dioxo-8,11,13-triazatetracyclo[7.7.0.02,7.011,15]hexadeca-1(9),2,4,6-tetraen-13-yl]benzoyl]pyrrolidine-2-carboxylic acid