Problem statement: Answer the multiple-choice question.
Question: Which drug has a 1.374% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Nc1ccc(-n2nnnc2-c2ccco2)cc1
b. COc1ccccc1CNC(=O)c1ccc(CS(=O)(=O)c2ccc(C)cc2)o1
c. COC(=O)[C@H](CCSC)NC(=O)Nc1ccc(C)cc1
d. COc1ccc([C@@H](OC)[C@@]2(Cc3ccc(O)cc3)N=C(N)N(C)C2=O)cc1
e. Cc1ccc(S(=O)(=O)N/N=C/c2ccc(OCC(=O)N3CCOCC3)cc2)cc1
Answer: d. COc1ccc([C@@H](OC)[C@@]2(Cc3ccc(O)cc3)N=C(N)N(C)C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@@H](OC)[C@@]2(Cc3ccc(O)cc3)N=C(N)N(C)C2=O)cc1
COc1ccc([C@@H](OC)[C@@]2(Cc3ccc(O)cc3)N=C(N)N(C)C2=O)cc1
(5R)-2-amino-5-[(4-hydroxyphenyl)methyl]-5-[(R)-methoxy-(4-methoxyphenyl)methyl]-3-methylimidazol-4-one