Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -40.922% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: Cc1oc2c(F)c(F)c(F)c(F)c2c1S(=O)(=O)Nc1cccc(C(F)(F)F)c1
b: COc1ccc(Oc2cccc(Cl)c2CNC(=O)CCC(=O)O)cc1
c: Cc1ccc(C)c(OCCn2cc(/C=C(\C#N)C(=O)NCc3cccs3)c3ccccc32)c1
d: CS(=O)(=O)N(CC(=O)N1CCc2ccccc2C1)c1ccc(Br)cc1
e: N#Cc1ccc(CN2CCN(C(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)CC2)cc1
Answer: e. N#Cc1ccc(CN2CCN(C(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#Cc1ccc(CN2CCN(C(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)CC2)cc1
N#Cc1ccc(CN2CCN(C(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)CC2)cc1
4-[[4-[4-(azepan-1-ylsulfonyl)benzoyl]piperazin-1-yl]methyl]benzonitrile