Problem statement: Answer the MCQ question.
Query: Which drug has a -6.017% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. O=C(NCC1CCCO1)c1cccc(S(=O)(=O)Nc2ccc(F)cc2)c1
b. COc1ccc(-c2csc3ncnc(N4CCN(S(=O)(=O)c5ccc(Cl)s5)CC4)c23)cc1
c. COc1cc2c(cc1OC)C(c1ccc([N+](=O)[O-])cc1)N(C(C)=O)CC2
d. COc1ccc(N2CC(C)Cn3c2nc2c3c(=O)[nH]c(=O)n2C)cc1
Answer: b. COc1ccc(-c2csc3ncnc(N4CCN(S(=O)(=O)c5ccc(Cl)s5)CC4)c23)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2csc3ncnc(N4CCN(S(=O)(=O)c5ccc(Cl)s5)CC4)c23)cc1
COc1ccc(-c2csc3ncnc(N4CCN(S(=O)(=O)c5ccc(Cl)s5)CC4)c23)cc1
4-[4-(5-chlorothiophen-2-yl)sulfonylpiperazin-1-yl]-5-(4-methoxyphenyl)thieno[2,3-d]pyrimidine