Problem statement: Answer the multiple choice question.
Question: Which drug has a -72.786% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1oc(-c2ccc(Cl)cc2)nc1CS(=O)CC(=O)NC1CCCCC1
b) COc1ccc(-n2nc(C(=O)c3cccs3)cc(-c3nc4ccccc4[nH]3)c2=N)cc1
c) COc1ccc(S(=O)(=O)NCc2cccs2)cc1
d) CCCS(=O)(=O)Nc1c(OC)ccc2c1c(C(=O)OCC)c(C)n2C
e) O=C(C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1)N1CCN(c2cccc(Cl)c2)CC1
Answer: e. O=C(C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1)N1CCN(c2cccc(Cl)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1)N1CCN(c2cccc(Cl)c2)CC1
O=C(C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1)N1CCN(c2cccc(Cl)c2)CC1
[4-(3-chlorophenyl)piperazin-1-yl]-[1-(7,8,9,10-tetrahydro-6H-purino[9,8-a]azepin-4-yl)piperidin-3-yl]methanone