Task: Answer the multiple choice question.
Query: Which drug exhibits a -25.334% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1ccc(C2C3=C(CC(C)(C)CC3=O)OC3=C2C(=O)CC(C)(C)C3)cc1
b. O=[N+]([O-])c1cccc(S(=O)(=O)Nc2ccc(S(=O)(=O)N3CCCC3)cc2)c1
c. Cc1ccc(-c2cc(C(=O)N/N=C/c3ccoc3)c3ccccc3n2)cc1
d. COC(=O)Nc1nn(-c2ccc(Cl)cc2)c(=O)c(C#N)c1C
e. CC(C)OC(=O)CSc1nc(Cc2cccs2)nc2ccccc12
Answer: d. COC(=O)Nc1nn(-c2ccc(Cl)cc2)c(=O)c(C#N)c1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)Nc1nn(-c2ccc(Cl)cc2)c(=O)c(C#N)c1C
COC(=O)Nc1nn(-c2ccc(Cl)cc2)c(=O)c(C#N)c1C
methyl N-[1-(4-chlorophenyl)-5-cyano-4-methyl-6-oxopyridazin-3-yl]carbamate