Problem statement: Answer the multiple choice question.
Question: Which drug has a -69.640% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) O=C(CSc1nc(=O)n(CCCN2CCOCC2)c2c1CCCC2)Nc1cccc([N+](=O)[O-])c1
(b) O=C(NCc1ccc2c(c1)OCO2)c1ccc(Cl)s1
(c) CCOC(=O)C1(CCc2ccccc2)CCN(Cc2cccc3cnccc23)CC1
(d) Cc1ccc(-n2ncc3c(=O)n(CC(=O)NCc4ccco4)cnc32)cc1
(e) CC(C)CNC(=O)/C(C#N)=C1\N=C(NC(=O)c2ccco2)c2ccccc21
Answer: c. CCOC(=O)C1(CCc2ccccc2)CCN(Cc2cccc3cnccc23)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1(CCc2ccccc2)CCN(Cc2cccc3cnccc23)CC1
CCOC(=O)C1(CCc2ccccc2)CCN(Cc2cccc3cnccc23)CC1
ethyl 1-(isoquinolin-5-ylmethyl)-4-(2-phenylethyl)piperidine-4-carboxylate