Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -46.677% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] CC(=O)c1ccc(CC2SC(N)=NC2=O)cc1
[b] CCOC(=O)C(=O)Nc1nnc(SCc2ccc(F)cc2)s1
[c] Oc1ccccc1CNc1ccc(Br)cn1
[d] O=C(CCc1nnc2ccc(NCc3ccco3)nn12)N1CCN(c2ccc(F)cc2)CC1
Answer: d. O=C(CCc1nnc2ccc(NCc3ccco3)nn12)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCc1nnc2ccc(NCc3ccco3)nn12)N1CCN(c2ccc(F)cc2)CC1
O=C(CCc1nnc2ccc(NCc3ccco3)nn12)N1CCN(c2ccc(F)cc2)CC1
1-[4-(4-fluorophenyl)piperazin-1-yl]-3-[6-(furan-2-ylmethylamino)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]propan-1-one