Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -10.313% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a CCN(CC)CC(=O)Nc1sc2c(c1C(=O)c1cccs1)CCCC2
b COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccccc1
c CN(CCC#N)C(=O)CC(Cc1ccccc1)C1CCOC(C)(C)C1
Answer: b. COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccccc1
COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccccc1
methyl (1R,5S)-3-(3-cyanophenyl)-8-(2-phenoxyethylcarbamoyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate