Problem statement: Answer the MCQ question.
Query: Which compound has a 1.210% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) COc1ccc(-c2csc(NC(=S)NC(=O)/C=C/c3ccco3)n2)cc1OC
b) COc1cc(/C=C2/C(=O)ON=C2C)ccc1OCc1ccccc1F
c) CC(C)(C)c1ccc(CS(=O)(=O)CC2(O)CCN(C(=O)c3cccc(C(F)(F)F)c3)CC2)cc1
d) C/C(CC(=O)Nc1cccc(Cl)c1Cl)=N\NC(=O)C(=O)NC1CCCCC1
Answer: c. CC(C)(C)c1ccc(CS(=O)(=O)CC2(O)CCN(C(=O)c3cccc(C(F)(F)F)c3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)(C)c1ccc(CS(=O)(=O)CC2(O)CCN(C(=O)c3cccc(C(F)(F)F)c3)CC2)cc1
CC(C)(C)c1ccc(CS(=O)(=O)CC2(O)CCN(C(=O)c3cccc(C(F)(F)F)c3)CC2)cc1
[4-[(4-tert-butylphenyl)methylsulfonylmethyl]-4-hydroxypiperidin-1-yl]-[3-(trifluoromethyl)phenyl]methanone