Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 10.884% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: O=C(COc1ccccc1F)NNC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3
b: OCCN1CCN(c2ncnc3sc4c(c23)CCCC4)CC1
c: CCN1CCN(c2cc(C)c3cc(NC(=O)c4ccc(Br)o4)ccc3n2)CC1
d: COc1ccc2c(c1)OC[C@H]1[C@@H]2N2C(=O)CNC(=O)[C@@]2(C)[C@H]1c1ccccc1
Answer: d. COc1ccc2c(c1)OC[C@H]1[C@@H]2N2C(=O)CNC(=O)[C@@]2(C)[C@H]1c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2c(c1)OC[C@H]1[C@@H]2N2C(=O)CNC(=O)[C@@]2(C)[C@H]1c1ccccc1
COc1ccc2c(c1)OC[C@H]1[C@@H]2N2C(=O)CNC(=O)[C@@]2(C)[C@H]1c1ccccc1
(1S,10R,11R,12R)-5-methoxy-12-methyl-11-phenyl-8-oxa-14,17-diazatetracyclo[8.7.0.02,7.012,17]heptadeca-2(7),3,5-triene-13,16-dione