Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -31.888% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1ccc(N2CCN(C(=O)C3CCCN(S(=O)(=O)c4ccc(C)cc4)C3)CC2)cc1
b.) O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1
c.) Cc1cccc(C)c1NC(=O)CCn1cnc2ccccc2c1=O
d.) COCCN(C(=S)Nc1ccc(OC)cc1)C1CCN(C(C)C)CC1
e.) O=C(Nc1ccc(C(=O)N2CCCC2)cc1)c1ccccc1F
Answer: b. O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1
O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1
N-[3-[4-(3-fluorophenyl)sulfonylpiperazin-1-yl]-3-oxopropyl]-4-(trifluoromethoxy)benzenesulfonamide