Problem statement: Answer the MCQ question.
Query: Which drug has a -1.707% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) O=C(NCCc1ccccc1)[C@@H]1CC=C[C@@H]2CCN(Cc3ccccc3)C(=O)[C@@H]21
b) CCOC(=O)c1cnc2c(Cl)cccc2c1NCCN1CCOCC1
c) CCOC(=O)c1c(NC(=O)CSc2ncccn2)sc(C(=O)NC)c1C
d) COCc1ccc(C(=O)N2CCC(CCC(=O)NCc3ccc(F)cc3)CC2)o1
Answer: a. O=C(NCCc1ccccc1)[C@@H]1CC=C[C@@H]2CCN(Cc3ccccc3)C(=O)[C@@H]21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCCc1ccccc1)[C@@H]1CC=C[C@@H]2CCN(Cc3ccccc3)C(=O)[C@@H]21
O=C(NCCc1ccccc1)[C@@H]1CC=C[C@@H]2CCN(Cc3ccccc3)C(=O)[C@@H]21
(4aS,8R,8aS)-2-benzyl-1-oxo-N-(2-phenylethyl)-3,4,4a,7,8,8a-hexahydroisoquinoline-8-carboxamide