Problem statement: Answer the multiple choice question.
Question: Which compound has a -11.777% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(-c2cc(C(=O)Nc3cc(OC)c(OC)c(OC)c3)no2)cc1
b. COc1ccc([C@H]2CC(=O)C=C(c3cccc(Cl)c3)C2)cc1
c. CC1CCCC(C)N1/N=C/c1c[nH]c2ccc(Br)cc12
d. O=c1[nH]c2ccccc2c(O)c1SCCO
e. COc1ccc(CC(=O)Nc2ccccc2-c2ccccc2)cc1OC
Answer: b. COc1ccc([C@H]2CC(=O)C=C(c3cccc(Cl)c3)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@H]2CC(=O)C=C(c3cccc(Cl)c3)C2)cc1
COc1ccc([C@H]2CC(=O)C=C(c3cccc(Cl)c3)C2)cc1
(5R)-3-(3-chlorophenyl)-5-(4-methoxyphenyl)cyclohex-2-en-1-one