Problem statement: Answer the MCQ question.
Query: Which drug has a -28.867% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a CN1C2CCC1/C(=C\c1ccc(F)cc1)C(=O)/C2=C/c1ccc(F)cc1
b CCCCn1c(=O)c(C(=O)OCC)c(O)c2ccccc21
c Cl.c1ccc(C2CCC(N3CCNCC3)CC2)cc1
d COc1ccc(C2C(=O)N(CCc3ccccc3)CC(=O)N2C2CCCCC2)cc1
e CCCCCC(=O)N1CC2(CC(c3cccc(NC(=O)CC(c4ccccc4)c4ccccc4)c3)=NO2)C[C@@H]1C(N)=O
Answer: d. COc1ccc(C2C(=O)N(CCc3ccccc3)CC(=O)N2C2CCCCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2C(=O)N(CCc3ccccc3)CC(=O)N2C2CCCCC2)cc1
COc1ccc(C2C(=O)N(CCc3ccccc3)CC(=O)N2C2CCCCC2)cc1
4-cyclohexyl-3-(4-methoxyphenyl)-1-(2-phenylethyl)piperazine-2,5-dione