Problem statement: Answer the MCQ question.
Question: Which drug has a -5.238% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COC(=O)/C(=C(O)\C=C\c1ccccc1[N+](=O)[O-])c1nc2ccccc2[nH]1
(b) O=C(NCc1ccccc1)NC1(C(=O)N2CCCC2)CCCCC1
(c) CN(CC(=O)Nc1cccc(S(=O)(=O)NC2=NCCC2)c1)Cc1ccccc1Cl
(d) Cc1ccc(S(=O)(=O)NN=C2C3CC4CC(C3)CC2C4)cc1[N+](=O)[O-]
(e) O=C(N/N=C/c1c(O)n(Cc2ccc(F)cc2)c(=S)[nH]c1=O)c1ccncc1
Answer: c. CN(CC(=O)Nc1cccc(S(=O)(=O)NC2=NCCC2)c1)Cc1ccccc1Cl
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(CC(=O)Nc1cccc(S(=O)(=O)NC2=NCCC2)c1)Cc1ccccc1Cl
CN(CC(=O)Nc1cccc(S(=O)(=O)NC2=NCCC2)c1)Cc1ccccc1Cl
2-[(2-chlorophenyl)methyl-methylamino]-N-[5-(3,4-dihydro-2H-pyrrol-5-ylsulfamoyl)phenyl]acetamide