Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -40.152% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(C3CC3)N(C3CC3)C=C2C1=O
b. O=C(NCCNc1ccc(Cl)cc1[N+](=O)[O-])c1cccnc1
c. O=C(NCCN1C(=O)S/C(=C/c2cccnc2)C1=O)C1=NN(c2ccccc2)C(=O)CC1
d. CCn1c(SCC(=O)Nc2ccc(C(C)=O)cc2)nc2ccccc21
Answer: c. O=C(NCCN1C(=O)S/C(=C/c2cccnc2)C1=O)C1=NN(c2ccccc2)C(=O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCCN1C(=O)S/C(=C/c2cccnc2)C1=O)C1=NN(c2ccccc2)C(=O)CC1
O=C(NCCN1C(=O)S/C(=C/c2cccnc2)C1=O)C1=NN(c2ccccc2)C(=O)CC1
N-[2-[(5E)-2,4-dioxo-5-(pyridin-3-ylmethylidene)-1,3-thiazolidin-3-yl]ethyl]-6-oxo-1-phenyl-4,5-dihydropyridazine-3-carboxamide