Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 12.368% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CC1(C)Cc2c(sc(NC(=O)c3ccc4c(c3)OCCO4)c2C(N)=O)C(C)(C)N1
[b] CC(C)OC(=O)CSc1nnnn1-c1ccc2c(c1)OCCO2
[c] Cc1cccc2cc3c(NC(=O)CC(C)C)nn(C)c3nc12
[d] COc1cccc(-n2c(SCC(=O)N3CCCCC3)nc3c([nH]c4ccccc43)c2=O)c1
[e] O=C(c1ccccc1)N1CCN(CC(O)COc2ccc(Br)cc2)CC1
Answer: d. COc1cccc(-n2c(SCC(=O)N3CCCCC3)nc3c([nH]c4ccccc43)c2=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(-n2c(SCC(=O)N3CCCCC3)nc3c([nH]c4ccccc43)c2=O)c1
COc1cccc(-n2c(SCC(=O)N3CCCCC3)nc3c([nH]c4ccccc43)c2=O)c1
3-(3-methoxyphenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one