Problem statement: Answer the multiple-choice question.
Query: Which drug has a -16.087% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCOCCOC(=O)Cn1cnc2scc(-c3ccc(C)cc3)c2c1=O
(b) Cc1ccc(Cn2nc(C)c(NC(=O)CCCn3nc([N+](=O)[O-])c(Cl)c3C)c2C)cc1
(c) COC(=O)C(=CC(=CN(C)C)C=C(C(=O)OC)C(=O)OC)C(=O)OC
(d) Cc1ccccc1/C=N/n1c(C2CCCCC2)n[nH]c1=S
(e) COc1cc2c(cc1OC)C(C)N(C(=O)c1ccc(Br)o1)CC2
Answer: e. COc1cc2c(cc1OC)C(C)N(C(=O)c1ccc(Br)o1)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(C)N(C(=O)c1ccc(Br)o1)CC2
COc1cc2c(cc1OC)C(C)N(C(=O)c1ccc(Br)o1)CC2
(5-bromofuran-2-yl)-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)methanone