Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -14.426% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(OCC(O)CN(C)C(=O)/C=C/c2cccc([N+](=O)[O-])c2)cc1
b. NC(=O)c1ccsc1NC(=O)COC(=O)c1cnccn1
c. CCOc1ccc2nc(NCCNC(=S)NCCCN(C)C)c(C#N)cc2c1
d. COc1ccc(Cn2c(O)c(C=NCCN3CCOCC3)c(=O)[nH]c2=O)cc1
e. CNC(=S)NNC(=O)c1ccccc1Cl
Answer: d. COc1ccc(Cn2c(O)c(C=NCCN3CCOCC3)c(=O)[nH]c2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(Cn2c(O)c(C=NCCN3CCOCC3)c(=O)[nH]c2=O)cc1
COc1ccc(Cn2c(O)c(C=NCCN3CCOCC3)c(=O)[nH]c2=O)cc1
6-hydroxy-1-[(4-methoxyphenyl)methyl]-5-(2-morpholin-4-ylethyliminomethyl)pyrimidine-2,4-dione