Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -23.453% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CC1(C)CC(=O)C(C=NCCN2CCN(C(=O)Cc3ccc(F)cc3)CC2)=C(O)C1
b: Cc1cc(C)n2nc(SCn3nnc4ccccc4c3=O)nc2n1
c: Cc1cc(C)n2c(SCc3cccs3)nnc2n1
d: O=C(CN1CCCC1)Nc1ccc([N+](=O)[O-])cc1Cl
e: CCN(CC)CCCNC(=O)C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1
Answer: a. CC1(C)CC(=O)C(C=NCCN2CCN(C(=O)Cc3ccc(F)cc3)CC2)=C(O)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1(C)CC(=O)C(C=NCCN2CCN(C(=O)Cc3ccc(F)cc3)CC2)=C(O)C1
CC1(C)CC(=O)C(C=NCCN2CCN(C(=O)Cc3ccc(F)cc3)CC2)=C(O)C1
2-[2-[4-[2-(4-fluorophenyl)acetyl]piperazin-1-yl]ethyliminomethyl]-3-hydroxy-5,5-dimethylcyclohex-2-en-1-one