Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a -13.866% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a CCc1ccc(-c2csc(-c3c[nH]c4ccccc34)n2)cc1
b CCN(CC(=O)Nc1cc(Cl)ccc1OC)CC(=O)NC1CCS(=O)(=O)C1.O=C(O)C(=O)O
c COc1ccccc1NC(=S)NC12CN3CN(CN(C3)C1)C2
d CCOc1cccc(CN2CCCC(N3CCc4cc(OC)c(OC)cc4C3)C2)c1O
e COc1cc(C2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(Cc4ccco4)CC(=O)N23)cc(OC)c1OC
Answer: e. COc1cc(C2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(Cc4ccco4)CC(=O)N23)cc(OC)c1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(C2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(Cc4ccco4)CC(=O)N23)cc(OC)c1OC
COc1cc(C2c3[nH]c4ccccc4c3C[C@@H]3C(=O)N(Cc4ccco4)CC(=O)N23)cc(OC)c1OC
(8R)-6-(furan-2-ylmethyl)-2-(3,4,5-trimethoxyphenyl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione