Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -11.960% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a) O=C(COC(=O)/C=C/c1ccc(Cl)cc1Cl)NCCC1=CCCCC1
b) COC(=O)NC1(C(F)(F)F)C(=O)Nc2c1c(=O)n(C)c(=O)n2C
c) COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1Cc2ccccc2C1
Answer: c. COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1Cc2ccccc2C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1Cc2ccccc2C1
COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1Cc2ccccc2C1
methyl (1R,5S)-8-(2,3-dihydro-1H-inden-2-ylcarbamoyl)-3-(3,4-dimethoxyphenyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate