Problem statement: Answer the MCQ question.
Query: Which compound has a -42.948% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] Cl.O=C1CC(N2CCN(Cc3ccccc3)CC2)C(=O)N1c1ccc2c(c1)OCCO2
[b] COc1cccc(CNC(=O)CCCn2ncn3c(cc4occc43)c2=O)c1
[c] CN(C)S(=O)(=O)c1ccc(Cl)c(NC(=O)COC(=O)[C@@H]2CCCN2C(=O)c2cccs2)c1
[d] N#Cc1sc2nc(-c3cccs3)cc(-c3ccc(Cl)cc3)c2c1N
[e] Cc1ccc(COC(=O)c2cccc(S(=O)(=O)N3CCCCCC3)c2)cc1
Answer: b. COc1cccc(CNC(=O)CCCn2ncn3c(cc4occc43)c2=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)CCCn2ncn3c(cc4occc43)c2=O)c1
COc1cccc(CNC(=O)CCCn2ncn3c(cc4occc43)c2=O)c1
N-[(3-methoxyphenyl)methyl]-4-(9-oxo-5-oxa-1,10,11-triazatricyclo[6.4.0.02,6]dodeca-2(6),3,7,11-tetraen-10-yl)butanamide