Task: Answer the multiple choice question.
Question: Which drug has a 15.727% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C1CCCN2N=C(SCC(=O)Nc3ccc(OC(F)(F)F)cc3)SC2=N1
b) CCOC(=O)N1CCC(N2CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)CC1.O=C(O)C(=O)O
c) CC(C(=O)Nc1ccc(F)c(F)c1F)N(C)CC(=O)Nc1ccccc1Br
d) O=C(NCC1OCCCN1S(=O)(=O)c1cc(F)ccc1F)C(=O)NC1CCCCC1
e) CCCN(Cc1cc2cc(C)ccc2[nH]c1=O)C(=O)c1ccccn1
Answer: a. O=C1CCCN2N=C(SCC(=O)Nc3ccc(OC(F)(F)F)cc3)SC2=N1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1CCCN2N=C(SCC(=O)Nc3ccc(OC(F)(F)F)cc3)SC2=N1
O=C1CCCN2N=C(SCC(=O)Nc3ccc(OC(F)(F)F)cc3)SC2=N1
2-[(8-oxo-6,7-dihydro-5H-[1,3,4]thiadiazolo[3,2-a][1,3]diazepin-2-yl)sulfanyl]-N-[4-(trifluoromethoxy)phenyl]acetamide