Task: Answer the multiple-choice question.
Query: Which drug exhibits a -15.686% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(NC2=C(C(C)=O)C(c3ccc(OC)c(OC)c3)C(C(C)=O)C(C)(O)C2)cc1
b) c1ccc2c(Cn3ccnc3)c[nH]c2c1
c) Cc1ccc(-c2nnc(Nc3ccc(OCC(N)=O)cc3)c3ccccc23)cc1S(N)(=O)=O
d) COc1cccc(Nc2nc(N)c([N+](=O)[O-])c(N3CCOCC3)n2)c1
e) CC1CC(C)CN(C(=O)C2CCN(S(=O)(=O)c3c(Cl)cccc3Cl)CC2)C1
Answer: e. CC1CC(C)CN(C(=O)C2CCN(S(=O)(=O)c3c(Cl)cccc3Cl)CC2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1CC(C)CN(C(=O)C2CCN(S(=O)(=O)c3c(Cl)cccc3Cl)CC2)C1
CC1CC(C)CN(C(=O)C2CCN(S(=O)(=O)c3c(Cl)cccc3Cl)CC2)C1
[1-(2,6-dichlorophenyl)sulfonylpiperidin-4-yl]-(3,5-dimethylpiperidin-1-yl)methanone