Problem statement: Answer the MCQ question.
Query: Which drug has a -2.633% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CCOC(=O)N1CN(C(=O)OCC)CN(C(=O)OCC)C1
b CC(C)C[C@@H](C(=O)OC(C)(C)C)n1cc(-c2cc(C(=O)N3CCN(C(=O)OC(C)(C)C)CC3)cc(-c3cn([C@@H](CCC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)nn3)c2)nn1
c CCOc1ccc(N(C(C)C(=O)N2CCCCCC2)S(C)(=O)=O)cc1
d CCOC(=O)C1=C(C)OC(N)=C(C#N)C1c1cccc(C)c1
e O=C(Nc1cccc(F)c1)/C(=C\c1cccnc1)NC(=O)c1cccs1
Answer: e. O=C(Nc1cccc(F)c1)/C(=C\c1cccnc1)NC(=O)c1cccs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1cccc(F)c1)/C(=C\c1cccnc1)NC(=O)c1cccs1
O=C(Nc1cccc(F)c1)/C(=C\c1cccnc1)NC(=O)c1cccs1
N-[(E)-3-(3-fluoroanilino)-3-oxo-1-pyridin-3-ylprop-1-en-2-yl]thiophene-2-carboxamide