Problem statement: Answer the MCQ question.
Query: Which drug has a 7.115% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. OC(C#CCCN1CCCCC1)(c1ccccc1)c1ccccc1
b. CCn1c(=O)c(C(=O)Nc2ccc(C)cc2C)c(O)c2ccccc21
c. Cc1ccc(C)c2[nH]c(=O)c(CN(CC3CCCO3)S(=O)(=O)c3ccc4c(c3)OCCO4)cc12
d. O=C(/C=C/c1cn(-c2ccccc2)nc1-c1ccccc1)Nc1ccc(C(=O)O)cc1
e. CC(=O)n1cc([C@@H]2C=C(C(=O)Nc3ccccc3)O[C@H](OCc3ccc(CO)cc3)C2)c2ccccc21
Answer: b. CCn1c(=O)c(C(=O)Nc2ccc(C)cc2C)c(O)c2ccccc21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCn1c(=O)c(C(=O)Nc2ccc(C)cc2C)c(O)c2ccccc21
CCn1c(=O)c(C(=O)Nc2ccc(C)cc2C)c(O)c2ccccc21
N-(2,4-dimethylphenyl)-1-ethyl-4-hydroxy-2-oxoquinoline-3-carboxamide