Problem statement: Answer the multiple-choice question.
Question: Which drug has a -37.889% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: N/C(=N\c1nc(CSc2ccc(Cl)cc2)cc(=O)[nH]1)Nc1cccc2ccccc12
b: CC(/C=C/c1ccc(OCc2ccccc2)cc1)=N\O
c: O=C1Nc2ccccc2C(=O)N2C[C@@H](O)C[C@H]12
d: COC(=O)c1ccc2c(=O)n(CCN3CCOCC3)c(SCC(=O)Nc3cccc(OC)c3)nc2c1
e: COc1ccccc1C(=O)Nc1ccccc1C(=O)NC1CCCCC1
Answer: d. COC(=O)c1ccc2c(=O)n(CCN3CCOCC3)c(SCC(=O)Nc3cccc(OC)c3)nc2c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc2c(=O)n(CCN3CCOCC3)c(SCC(=O)Nc3cccc(OC)c3)nc2c1
COC(=O)c1ccc2c(=O)n(CCN3CCOCC3)c(SCC(=O)Nc3cccc(OC)c3)nc2c1
methyl 2-[2-(3-methoxyanilino)-2-oxoethyl]sulfanyl-3-(2-morpholin-4-ylethyl)-4-oxoquinazoline-7-carboxylate