Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -62.403% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CCCn1ncc(/C=N/O)c1C
b: CC(C)CC(=O)c1c[nH]c(C(=O)NCc2ccc(F)cc2)c1
c: CCOC(=O)CN1C(=O)NC2(CCCc3ccccc32)C1=O
d: CCOC(=O)c1c[nH]n(-c2ccccc2)c1=O
e: CC1(C)CC(=O)C(C=NCC2CCN(C(=S)Nc3cccc(Cl)c3)CC2)=C(O)C1
Answer: e. CC1(C)CC(=O)C(C=NCC2CCN(C(=S)Nc3cccc(Cl)c3)CC2)=C(O)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1(C)CC(=O)C(C=NCC2CCN(C(=S)Nc3cccc(Cl)c3)CC2)=C(O)C1
CC1(C)CC(=O)C(C=NCC2CCN(C(=S)Nc3cccc(Cl)c3)CC2)=C(O)C1
N-(3-chlorophenyl)-4-[[(2-hydroxy-4,4-dimethyl-6-oxocyclohexen-1-yl)methylideneamino]methyl]piperidine-1-carbothioamide