Problem statement: Answer the MCQ question.
Question: Which drug has a 15.604% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COC(=O)c1cc2c(N)c(C(=O)c3ccc(Cl)cc3)sc2nc1C(OC)OC
b) COc1ccc2nnc(-c3ccc(C(F)(F)F)cc3)n2n1
c) CCCCCN(C(=O)CCC(=O)OCC(=O)N(CC#N)c1ccccc1)c1c(N)n(CCCC)c(=O)[nH]c1=O
d) Cc1ccccc1NC(=O)CC1SC(=O)N(c2ccccc2)C1=O
e) CCn1c(=O)n(CC)c2cc(N3CCCC3)c(NC(=O)c3ccc(C)cc3)cc21
Answer: d. Cc1ccccc1NC(=O)CC1SC(=O)N(c2ccccc2)C1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccccc1NC(=O)CC1SC(=O)N(c2ccccc2)C1=O
Cc1ccccc1NC(=O)CC1SC(=O)N(c2ccccc2)C1=O
2-(2,4-dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(2-methylphenyl)acetamide