Problem statement: Answer the multiple-choice question.
Query: Which compound has a 21.311% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) CCOC(=O)CCCCC(=O)c1[nH]c(=O)[nH]c1CSc1nnc2c3cc(Br)ccc3n(C)c2n1
(b) CCOC(=O)C1=C(C)OC(N)=C(C#N)C1c1ccc(C)s1
(c) Cc1cccc(N(Cc2cc3ccccc3[nH]c2=O)C(=O)c2ccco2)c1C
(d) COc1ccc([C@@H]2[C@@H]3C(=O)N(C(C)(C)C)C(=O)[C@@H]3[C@]3(CC(C)C)C(=O)N(c4cccc(Br)c4)C(=O)N23)cc1
Answer: d. COc1ccc([C@@H]2[C@@H]3C(=O)N(C(C)(C)C)C(=O)[C@@H]3[C@]3(CC(C)C)C(=O)N(c4cccc(Br)c4)C(=O)N23)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@@H]2[C@@H]3C(=O)N(C(C)(C)C)C(=O)[C@@H]3[C@]3(CC(C)C)C(=O)N(c4cccc(Br)c4)C(=O)N23)cc1
COc1ccc([C@@H]2[C@@H]3C(=O)N(C(C)(C)C)C(=O)[C@@H]3[C@]3(CC(C)C)C(=O)N(c4cccc(Br)c4)C(=O)N23)cc1
(1S,2R,7S,8R)-4-(3-bromophenyl)-10-tert-butyl-7-(4-methoxyphenyl)-2-(2-methylpropyl)-4,6,10-triazatricyclo[6.3.0.02,6]undecane-3,5,9,11-tetrone