Task: Answer the multiple-choice question.
Query: Which drug has a -6.488% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(COC(=O)c1ccccc1Br)Nc1nnc(-c2ccccc2)o1
b.) COc1cc(C(=O)N2CCCCC2)ccc1OCC(=O)Nc1ccc(F)cc1
c.) N#Cc1ccccc1OCC(=O)OCC(=O)c1ccc[nH]1
d.) COc1ccc2c(c1O)-c1c(OC)c(OC)cc3c1[C@H](C2)N(C)CC3
e.) CC1CCCN(CCCNC(=O)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2)C1
Answer: e. CC1CCCN(CCCNC(=O)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1CCCN(CCCNC(=O)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2)C1
CC1CCCN(CCCNC(=O)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2)C1
4-[(2,1,3-benzothiadiazol-4-ylsulfonylamino)methyl]-N-[3-(3-methylpiperidin-1-yl)propyl]cyclohexane-1-carboxamide