Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -13.466% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: Cc1ccc2c(CC(=O)OC(C)C(=O)Nc3ncc(Cl)cc3Cl)coc2c1
b: CCOc1ccc(C(=O)c2cc3ccc(O)cc3oc2=O)cc1
c: CCCc1nc(NCCO)c(C#N)c2c1CCCC2
d: COc1ccc(C2C(C#N)=C(/N=C/N3CCOCC3)OC3=C2C(=O)CC(C)(C)C3)cc1OC
e: COc1ccc(/C=N/NC(=O)CCc2n[nH]c(=O)[nH]c2=O)cc1O
Answer: d. COc1ccc(C2C(C#N)=C(/N=C/N3CCOCC3)OC3=C2C(=O)CC(C)(C)C3)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2C(C#N)=C(/N=C/N3CCOCC3)OC3=C2C(=O)CC(C)(C)C3)cc1OC
COc1ccc(C2C(C#N)=C(/N=C/N3CCOCC3)OC3=C2C(=O)CC(C)(C)C3)cc1OC
4-(3,4-dimethoxyphenyl)-7,7-dimethyl-2-[(E)-morpholin-4-ylmethylideneamino]-5-oxo-6,8-dihydro-4H-chromene-3-carbonitrile