Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -13.618% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Nc1c(-c2ccc(Cl)cc2)cnn1-c1ccc(Cc2ccc(Cl)cc2Cl)nn1
b) COc1cc(CN2CCC(C(=O)N3CCCC(C)C3)CC2)cc(OC)c1O.O=C(O)C(=O)O
c) Nc1nonc1-c1nc2ccccc2n1Cc1ccc(Cl)cc1
d) COc1cccc(-c2cc(C(=O)N3CCCc4ccccc43)no2)c1
e) Brc1ccc(C=Nc2ccc3c(c2)OCCOCCOCCO3)s1
Answer: d. COc1cccc(-c2cc(C(=O)N3CCCc4ccccc43)no2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(-c2cc(C(=O)N3CCCc4ccccc43)no2)c1
COc1cccc(-c2cc(C(=O)N3CCCc4ccccc43)no2)c1
3,4-dihydro-2H-quinolin-1-yl-[5-(3-methoxyphenyl)-1,2-oxazol-3-yl]methanone