Problem statement: Answer the MCQ question.
Query: Which drug has a -25.350% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCOc1ccc(CN(C(=O)c2cccs2)C2CCS(=O)(=O)C2)cc1
(b) CNS(=O)(=O)c1ccc(C(=O)NCC(=O)NCCc2ccc3c(c2)OCCO3)cc1
(c) COC(=O)C1CCN(C(=O)CCC2CCCCC2)CC1
(d) COc1ccc(C(=O)NC2CCN(CC(=O)Nc3cccc(OC)c3)CC2)cc1
(e) N/C(=N\OC(=O)CCC1CCCC1)c1ccc([N+](=O)[O-])cc1
Answer: d. COc1ccc(C(=O)NC2CCN(CC(=O)Nc3cccc(OC)c3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)NC2CCN(CC(=O)Nc3cccc(OC)c3)CC2)cc1
COc1ccc(C(=O)NC2CCN(CC(=O)Nc3cccc(OC)c3)CC2)cc1
4-methoxy-N-[1-[2-(3-methoxyanilino)-2-oxoethyl]piperidin-4-yl]benzamide