Task: Answer the MCQ question.
Query: Which compound has a -8.456% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: Cc1ccc(N)cc1S(=O)(=O)N(C)C
b: O=C(Cn1cnc2c(cnn2-c2ccccc2)c1=O)N1CCN(c2ccc(F)cc2)CC1
c: Cc1ccc2nc(Nc3ccc(F)cc3)c3nncn3c2c1
d: CCOC(=O)c1ccccc1OCc1cc(/C=N/NC(=O)c2cccnc2)ccc1OC
e: COC(=O)CCC(=O)c1ccn(S(=O)(=O)c2ccccc2)c1
Answer: b. O=C(Cn1cnc2c(cnn2-c2ccccc2)c1=O)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Cn1cnc2c(cnn2-c2ccccc2)c1=O)N1CCN(c2ccc(F)cc2)CC1
O=C(Cn1cnc2c(cnn2-c2ccccc2)c1=O)N1CCN(c2ccc(F)cc2)CC1
5-[2-[4-(4-fluorophenyl)piperazin-1-yl]-2-oxoethyl]-1-phenylpyrazolo[3,4-d]pyrimidin-4-one