Task: Answer the multiple-choice question.
Question: Which drug has a -8.296% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Cc1coc2cc3oc(=O)c4c(c3cc12)CCC4
(b) CCN1CCC(Nc2cccc(F)c2)CC1
(c) Cc1ccc(C)c(NCC(=O)NNC(=S)Nc2ccccc2)c1
(d) O=c1[nH]c(C2CCN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)CC2)nc2c1nnn2Cc1cccc(F)c1
(e) CCCOc1ccccc1NC(=O)c1c(-c2ccccc2)noc1C
Answer: d. O=c1[nH]c(C2CCN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)CC2)nc2c1nnn2Cc1cccc(F)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=c1[nH]c(C2CCN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)CC2)nc2c1nnn2Cc1cccc(F)c1
O=c1[nH]c(C2CCN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)CC2)nc2c1nnn2Cc1cccc(F)c1
3-[(3-fluorophenyl)methyl]-5-[1-[4-(trifluoromethyl)phenyl]sulfonylpiperidin-4-yl]-6H-triazolo[4,5-d]pyrimidin-7-one