Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -1.370% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1cc(C)cc(OCC(=O)N/N=C/c2ccco2)c1
b CCC(=O)c1ccc(OCC(=O)OCC(=O)NC2CCCCCC2)cc1
c CCOC(=O)c1cccc(NC(=O)N2CCOCC2)c1
d CCc1cccc(N(C(=O)c2csnn2)C(C(=O)NC2CCCCC2)c2cccnc2)c1
e CC(=O)c1ccc(N2CCN(C(=O)C3CCN(S(=O)(=O)c4ccc5c(c4)CC(C)N5C(C)=O)CC3)CC2)cc1
Answer: e. CC(=O)c1ccc(N2CCN(C(=O)C3CCN(S(=O)(=O)c4ccc5c(c4)CC(C)N5C(C)=O)CC3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=O)c1ccc(N2CCN(C(=O)C3CCN(S(=O)(=O)c4ccc5c(c4)CC(C)N5C(C)=O)CC3)CC2)cc1
CC(=O)c1ccc(N2CCN(C(=O)C3CCN(S(=O)(=O)c4ccc5c(c4)CC(C)N5C(C)=O)CC3)CC2)cc1
1-[4-[4-[1-[(1-acetyl-2-methyl-2,3-dihydroindol-5-yl)sulfonyl]piperidine-4-carbonyl]piperazin-1-yl]phenyl]ethanone