Problem statement: Answer the MCQ question.
Question: Which drug has a -41.034% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C(CCS(=O)(=O)c1cccs1)N1CCN(c2ccc(F)cc2)CC1
b) C=CCNC(=O)C1=NN(c2c(F)c(F)cc(F)c2F)C(=O)CC1
c) Cc1ccc(/C(O)=C2\C(=O)C(=O)N(c3cc(C)on3)C2c2cccc(Cl)c2)cc1
d) COc1ccc(Br)c(OC)c1C(=O)NC(=O)Nc1nc(C)cc(C)n1
e) CCCCCNCc1ccc(OCc2ccc(Cl)nc2)c(OC)c1
Answer: a. O=C(CCS(=O)(=O)c1cccs1)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCS(=O)(=O)c1cccs1)N1CCN(c2ccc(F)cc2)CC1
O=C(CCS(=O)(=O)c1cccs1)N1CCN(c2ccc(F)cc2)CC1
1-[4-(4-fluorophenyl)piperazin-1-yl]-3-thiophen-2-ylsulfonylpropan-1-one