Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 7.711% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COC(=O)C1=C(c2ccc(OCc3ccccc3)cc2)C[C@@H]2CC[C@H]1N2C(=O)NCCCc1ccccc1
b. O=C(CNC(=O)c1cnccn1)Nc1ccc(F)c(F)c1F
c. C=CCn1c(SCC(=O)c2[nH]c(C)c(C(=O)OCC)c2C)nc2scc(-c3ccc(OC)c(OC)c3)c2c1=O
d. O=C(NC1CC1)c1ccc(CS(=O)c2ccccc2)o1
e. Cc1cccn2c(CNCCCOc3cccnc3)c(C(=O)N3CCOCC3)nc12
Answer: a. COC(=O)C1=C(c2ccc(OCc3ccccc3)cc2)C[C@@H]2CC[C@H]1N2C(=O)NCCCc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(OCc3ccccc3)cc2)C[C@@H]2CC[C@H]1N2C(=O)NCCCc1ccccc1
COC(=O)C1=C(c2ccc(OCc3ccccc3)cc2)C[C@@H]2CC[C@H]1N2C(=O)NCCCc1ccccc1
methyl (1R,5S)-3-(4-phenylmethoxyphenyl)-8-(3-phenylpropylcarbamoyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate