Task: Answer the multiple choice question.
Question: Which drug exhibits a 11.177% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccc(CCN(C(=O)C(F)(F)F)C(C(=O)NC2CCCCC2)c2ccc(C)s2)cc1OC
b. Cc1nnc2ccc(-c3cccc(NS(=O)(=O)c4ccccc4[N+](=O)[O-])c3)nn12
c. COc1ccc([C@@H]2[C@@H]3C(=O)N(C(C)(C)C)C(=O)[C@@H]3[C@]3(Cc4ccc(Cl)cc4)C(=O)N(c4cccc(F)c4)C(=O)N23)cc1
d. O=C(CSc1nnc(-c2cccs2)o1)N1CCCCC1
e. COC(=O)c1c[nH]n2c(=O)c(Cc3ccc(F)cc3)c(C)nc12
Answer: c. COc1ccc([C@@H]2[C@@H]3C(=O)N(C(C)(C)C)C(=O)[C@@H]3[C@]3(Cc4ccc(Cl)cc4)C(=O)N(c4cccc(F)c4)C(=O)N23)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@@H]2[C@@H]3C(=O)N(C(C)(C)C)C(=O)[C@@H]3[C@]3(Cc4ccc(Cl)cc4)C(=O)N(c4cccc(F)c4)C(=O)N23)cc1
COc1ccc([C@@H]2[C@@H]3C(=O)N(C(C)(C)C)C(=O)[C@@H]3[C@]3(Cc4ccc(Cl)cc4)C(=O)N(c4cccc(F)c4)C(=O)N23)cc1
(1S,2R,7S,8R)-10-tert-butyl-2-[(4-chlorophenyl)methyl]-4-(3-fluorophenyl)-7-(4-methoxyphenyl)-4,6,10-triazatricyclo[6.3.0.02,6]undecane-3,5,9,11-tetrone