Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -22.878% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CC(C)CN1C(=O)c2ccc(C(=O)Nc3nccs3)cc2C1=O
b. COc1ccc(NC(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)cc1
c. COc1ccc(-c2nc3ccc(C(=O)N4CCC5(CC4)OCCO5)cc3nc2-c2ccc(OC)cc2)cc1
d. COc1ccc(-c2cc(=O)oc3cc(OC(=O)C4CCCCC4)ccc23)cc1
e. COc1ccc(C(C[N+](=O)[O-])n2nc(C)cc2C)cc1
Answer: b. COc1ccc(NC(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)cc1
COc1ccc(NC(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)cc1
N-(4-methoxyphenyl)-3-[6-(4-methylpiperidin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]propanamide