Problem statement: Answer the MCQ question.
Question: Which drug has a -26.133% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1c(Cl)cc(C(=O)O)cc1Cl
(b) Cc1cc(C(=S)N2CCOCC2)c(C)n1C1CCCC1
(c) CC(C)n1cnnc1SCC(=O)Nc1ccc(Br)cc1F
(d) CCOC(=O)N1CCN(C(=O)/C=C/c2ccc(C(C)(C)C)cc2)CC1
(e) CCNc1nc(Oc2ccc(=O)n(-c3ccccc3)n2)nc(N2CCOCC2)n1
Answer: d. CCOC(=O)N1CCN(C(=O)/C=C/c2ccc(C(C)(C)C)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)/C=C/c2ccc(C(C)(C)C)cc2)CC1
CCOC(=O)N1CCN(C(=O)/C=C/c2ccc(C(C)(C)C)cc2)CC1
ethyl 4-[(E)-3-(4-tert-butylphenyl)prop-2-enoyl]piperazine-1-carboxylate