Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -45.507% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CC(NC(=O)c1ccc(Br)cc1)C(=O)NC1=NCCS1
b) CC(=O)c1ccc(Sc2nnnn2-c2ccccc2)c([N+](=O)[O-])c1
c) O=C(O)COc1ccc(NC(=O)c2ccco2)cc1
d) CCc1ccc(-c2csc(NC(=O)Oc3ccccc3)n2)cc1
e) COCCn1c(N)c(N(Cc2ccccc2)C(=O)c2ccc(-c3ccc(Cl)cc3)o2)c(=O)[nH]c1=O
Answer: e. COCCn1c(N)c(N(Cc2ccccc2)C(=O)c2ccc(-c3ccc(Cl)cc3)o2)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCn1c(N)c(N(Cc2ccccc2)C(=O)c2ccc(-c3ccc(Cl)cc3)o2)c(=O)[nH]c1=O
COCCn1c(N)c(N(Cc2ccccc2)C(=O)c2ccc(-c3ccc(Cl)cc3)o2)c(=O)[nH]c1=O
N-[6-amino-1-(2-methoxyethyl)-2,4-dioxopyrimidin-5-yl]-N-benzyl-5-(4-chlorophenyl)furan-2-carboxamide