Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -13.750% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1cccc(C(=O)NC(=S)N2CCN(c3ccc(C(F)(F)F)cc3[N+](=O)[O-])CC2)c1
b CCN1CCCC1CNC(=O)c1ccc(CS(=O)(=O)c2ccccc2C)o1
c CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)N1CCC(C(=O)N[C@H](C(=O)O)C(C)C)CC1
d COc1ccc(/C=C2\Sc3ccc(C(=O)N4CCOCC4)cc3N(C)C2=O)cc1
e Cc1cc(-c2n[nH]c(=S)n2/N=C/c2ccc(Br)s2)n[nH]1
Answer: b. CCN1CCCC1CNC(=O)c1ccc(CS(=O)(=O)c2ccccc2C)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1CCCC1CNC(=O)c1ccc(CS(=O)(=O)c2ccccc2C)o1
CCN1CCCC1CNC(=O)c1ccc(CS(=O)(=O)c2ccccc2C)o1
N-[(1-ethylpyrrolidin-2-yl)methyl]-5-[(2-methylphenyl)sulfonylmethyl]furan-2-carboxamide