Problem statement: Answer the MCQ question.
Query: Which compound has a -13.723% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) COc1ccc(C(=O)O)cc1S(=O)(=O)N1CCN(c2ccccn2)CC1
b.) COc1cc(OC)c(S(=O)(=O)NCc2cccnc2)cc1NC(C)=O
c.) COc1ccc(C(=O)NCC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1
d.) O=c1c2ccccc2nc(COc2ccccc2)n1/N=C/c1ccco1
Answer: c. COc1ccc(C(=O)NCC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)NCC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1
COc1ccc(C(=O)NCC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1
N-[2-[4-(furan-2-carbonyl)piperazin-1-yl]-2-oxoethyl]-4-methoxybenzamide