Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -18.734% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C(O)C(=O)O.O=C1CN(C(=O)CNCc2cccc(Cl)c2)c2ccccc2N1
b) CCOC(=O)C[C@H]1c2cc(F)ccc2S(=O)(=O)N1C1CCCC1
c) Cc1cccc(N(C(=O)c2csnn2)C(C(=O)NCc2ccccc2)c2ccncc2)c1
d) COc1ccc(Cc2nnc(NC(=O)Nc3ccc(C)cc3)s2)cc1OC
e) CN(C)S(=O)(=O)c1cccc(COC(=O)CN2C(=O)NC3(CCCC3)C2=O)c1
Answer: c. Cc1cccc(N(C(=O)c2csnn2)C(C(=O)NCc2ccccc2)c2ccncc2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cccc(N(C(=O)c2csnn2)C(C(=O)NCc2ccccc2)c2ccncc2)c1
Cc1cccc(N(C(=O)c2csnn2)C(C(=O)NCc2ccccc2)c2ccncc2)c1
N-[2-(benzylamino)-2-oxo-1-pyridin-4-ylethyl]-N-(3-methylphenyl)thiadiazole-4-carboxamide