Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -58.422% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCN(CCn1cccn1)C(=O)c1cc(COc2ccc(F)c(F)c2)on1
(b) O=C(COc1ccc(S(=O)(=O)N2CCOCC2)cc1Cl)N1CCCC1
(c) CC(OC(=O)CN1C(=O)C2CC=CCC2C1=O)C(=O)Nc1ccc(F)cc1Cl
(d) CCc1noc(C)c1C(=O)N(C)CC(=O)Nc1ccc(F)c(F)c1F
(e) CCC1(C)Cc2c(sc3nnn(CC(=O)Nc4ccccc4C)c(=O)c23)CO1
Answer: e. CCC1(C)Cc2c(sc3nnn(CC(=O)Nc4ccccc4C)c(=O)c23)CO1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC1(C)Cc2c(sc3nnn(CC(=O)Nc4ccccc4C)c(=O)c23)CO1
CCC1(C)Cc2c(sc3nnn(CC(=O)Nc4ccccc4C)c(=O)c23)CO1
2-(12-ethyl-12-methyl-3-oxo-11-oxa-8-thia-4,5,6-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5-trien-4-yl)-N-(2-methylphenyl)acetamide