Problem statement: Answer the multiple-choice question.
Question: Which drug has a -22.854% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: CCCn1c(N)c(N(CCOC)C(=O)c2ccc(N3CCCC3=O)cc2)c(=O)[nH]c1=O
b: NS(=O)(=O)c1ccc(CNC(=O)CCSCCC(=O)NCc2ccc(S(N)(=O)=O)cc2)cc1
c: Cn1cc(CNC(=O)C2CCC(=O)N(Cc3cccc(C(F)(F)F)c3)C2)cn1
d: CCOC(=O)N1CCN(C(=O)C2CCCN(c3ncnc4c3nc3n4CCCCC3)C2)CC1
Answer: d. CCOC(=O)N1CCN(C(=O)C2CCCN(c3ncnc4c3nc3n4CCCCC3)C2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)C2CCCN(c3ncnc4c3nc3n4CCCCC3)C2)CC1
CCOC(=O)N1CCN(C(=O)C2CCCN(c3ncnc4c3nc3n4CCCCC3)C2)CC1
ethyl 4-[1-(7,8,9,10-tetrahydro-6H-purino[9,8-a]azepin-4-yl)piperidine-3-carbonyl]piperazine-1-carboxylate