Task: Answer the multiple-choice question.
Query: Which drug exhibits a -11.638% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Cc1cc(C)n2nc(SCc3nnc(-c4ccccc4Br)o3)nc2n1
(b) COc1ccc(C2CC(=O)c3cnn(-c4nc(C)cc(C)n4)c3C2)cc1
(c) COc1ccc(NC(=S)NC(NC(C)=O)C(Cl)(Cl)Cl)c([N+](=O)[O-])c1
(d) COc1ccc(CCNC(=O)CSc2nc(O)c(CCC(C)C)c(=O)[nH]2)cc1OC
(e) Cl.Nc1nc(N2CCN(C(=O)c3ccco3)CC2)nc2ccccc12
Answer: b. COc1ccc(C2CC(=O)c3cnn(-c4nc(C)cc(C)n4)c3C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2CC(=O)c3cnn(-c4nc(C)cc(C)n4)c3C2)cc1
COc1ccc(C2CC(=O)c3cnn(-c4nc(C)cc(C)n4)c3C2)cc1
1-(4,6-dimethylpyrimidin-2-yl)-6-(4-methoxyphenyl)-6,7-dihydro-5H-indazol-4-one