Problem statement: Answer the MCQ question.
Query: What is the human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM of a compound with the SMILES Cc1cc(C)c(CN2CCN(C(=O)Cn3ccc(NC(=O)OCc4ccccc4)nc3=O)CC2)c(C)c1?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) -14.984
(b) -5.548
(c) 13.099
(d) -9.589
(e) 14.967
Answer: b. -5.548%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_10uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_10uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_10uM#}{herg_central_at_10uM__units}.
Cc1cc(C)c(CN2CCN(C(=O)Cn3ccc(NC(=O)OCc4ccccc4)nc3=O)CC2)c(C)c1
Cc1cc(C)c(CN2CCN(C(=O)Cn3ccc(NC(=O)OCc4ccccc4)nc3=O)CC2)c(C)c1
benzyl N-[2-oxo-1-[2-oxo-2-[4-[(2,4,6-trimethylphenyl)methyl]piperazin-1-yl]ethyl]pyrimidin-4-yl]carbamate