Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 23.119% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccc(NC2CCCN(C(=O)c3ccc4nccnc4c3)C2)cc1OC
b. O=C1CC(c2ccc(Br)cc2)NC(c2ccc(Br)cc2)C1c1ccccc1
c. Cc1nc2nc(SCC(=O)C(C)(C)C)[nH]c2cc1Br
d. CCOc1ccc(S(=O)(=O)NC2=NCCCCC2)cc1
e. N#C/C(=C\c1c(Oc2ccccc2Cl)nc2ccccn2c1=O)C(=O)NC1CCS(=O)(=O)C1
Answer: e. N#C/C(=C\c1c(Oc2ccccc2Cl)nc2ccccn2c1=O)C(=O)NC1CCS(=O)(=O)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#C/C(=C\c1c(Oc2ccccc2Cl)nc2ccccn2c1=O)C(=O)NC1CCS(=O)(=O)C1
N#C/C(=C\c1c(Oc2ccccc2Cl)nc2ccccn2c1=O)C(=O)NC1CCS(=O)(=O)C1
(E)-3-[2-(2-chlorophenoxy)-4-oxopyrido[1,2-a]pyrimidin-3-yl]-2-cyano-N-(1,1-dioxothiolan-3-yl)prop-2-enamide