Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -20.823% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1cc(OC)c(OC)cc1CNC(=O)c1ccc(S(=O)(=O)N2CCCCC2)cc1
(b) Cc1ccccc1-c1nnc(SCC(=O)N2CCCC2)o1
(c) COc1ccccc1N1CCN(C(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)CC1
(d) CN(C(=O)CSc1nnc(-c2c[nH]c3ccccc23)o1)C1CCS(=O)(=O)C1
(e) O=C(Nc1ccnn1C1CCN(Cc2ccn[nH]2)CC1)c1ccccc1
Answer: a. COc1cc(OC)c(OC)cc1CNC(=O)c1ccc(S(=O)(=O)N2CCCCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(OC)c(OC)cc1CNC(=O)c1ccc(S(=O)(=O)N2CCCCC2)cc1
COc1cc(OC)c(OC)cc1CNC(=O)c1ccc(S(=O)(=O)N2CCCCC2)cc1
4-piperidin-1-ylsulfonyl-N-[(2,4,5-trimethoxyphenyl)methyl]benzamide