Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -10.720% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccccc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)CCC(=O)N2
[b] CCOC(=O)C1CCN(C(=O)Nc2ccc(OC)c(OC)c2)CC1
[c] CCOC(=O)C1=NN(C(=O)Cc2ccccc2)C(O)(c2ccc(Cl)cc2)C1
[d] O=C(CN1C(=O)COc2ccccc21)NCCCN1CCN(c2ccccc2F)CC1
[e] COc1ccc2c(c1)C(C)=CC(C)(C)N2C(=O)CNCc1ccc2c(c1)OCO2.O=C(O)C(=O)O
Answer: d. O=C(CN1C(=O)COc2ccccc21)NCCCN1CCN(c2ccccc2F)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CN1C(=O)COc2ccccc21)NCCCN1CCN(c2ccccc2F)CC1
O=C(CN1C(=O)COc2ccccc21)NCCCN1CCN(c2ccccc2F)CC1
N-[3-[4-(2-fluorophenyl)piperazin-1-yl]propyl]-2-(3-oxo-1,4-benzoxazin-4-yl)acetamide