Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -6.290% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cn1c2c(c(=O)n(C)c1=O)C(CC(=O)Nc1ccccc1)C(=O)N2
b Cc1nn(C/C(C#N)=N\O)c(C)[n+]1N.[Cl-]
c COC(=O)/C(=C\Nc1ccc(Cl)cc1Cl)NC(=O)c1ccc(OC)cc1
d O=C1CN(S(=O)(=O)c2cc(C(F)(F)F)ccc2Cl)CCN1
e CN(CCCNC(=O)CCc1cn(C)c2ccccc12)C1CCCCC1
Answer: d. O=C1CN(S(=O)(=O)c2cc(C(F)(F)F)ccc2Cl)CCN1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1CN(S(=O)(=O)c2cc(C(F)(F)F)ccc2Cl)CCN1
O=C1CN(S(=O)(=O)c2cc(C(F)(F)F)ccc2Cl)CCN1
4-[[3-chloro-6-(trifluoromethyl)cyclohexa-1,3,5-trien-2-yl]sulfonyl]piperazin-2-one