Problem statement: Answer the multiple-choice question.
Query: Which compound has a -25.378% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C(NCc1cccc(C(F)(F)F)c1)C1CC(c2ccccc2F)=NO1
b) COC(=O)c1sccc1NC(=O)CC1C(=O)NCCN1C(=O)c1ccc(F)cc1
c) CC(Oc1ccccc1)C(=O)OCC(=O)NC(=O)NC1CCCCC1
d) O=C(NCc1ccco1)c1cc([N+](=O)[O-])ccc1N1CCOCC1
e) Oc1c(C(c2cccs2)N2CCN(c3ccccc3)CC2)ccc2cccnc12
Answer: d. O=C(NCc1ccco1)c1cc([N+](=O)[O-])ccc1N1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCc1ccco1)c1cc([N+](=O)[O-])ccc1N1CCOCC1
O=C(NCc1ccco1)c1cc([N+](=O)[O-])ccc1N1CCOCC1
N-(furan-2-ylmethyl)-2-morpholin-4-yl-5-nitrobenzamide