Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -1.894% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc2c(c1)C(=O)CC(c1ccc(OC)c(OC)c1)O2
b. Cc1nn(Cc2ccccc2)c(Cl)c1C(=O)Nc1ccc(OC(F)(F)F)cc1
c. CN1CCN(S(=O)(=O)c2cccc(C(=O)Oc3cccc(C#N)c3)c2)CC1
d. C/C(=C\c1cccc(Br)c1)C(=O)c1c(C)cc(C)[nH]c1=O
e. COc1ccccc1NC(=O)CN1C(=O)COc2ccc(S(=O)(=O)N3CCOCC3)cc21
Answer: c. CN1CCN(S(=O)(=O)c2cccc(C(=O)Oc3cccc(C#N)c3)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1CCN(S(=O)(=O)c2cccc(C(=O)Oc3cccc(C#N)c3)c2)CC1
CN1CCN(S(=O)(=O)c2cccc(C(=O)Oc3cccc(C#N)c3)c2)CC1
(3-cyanophenyl) 3-(4-methylpiperazin-1-yl)sulfonylbenzoate