Problem statement: Answer the MCQ question.
Query: Which compound has a -0.573% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCOc1ccc2c(c1)C(=O)c1cc(OCC(=O)O)ccc1-2
b.) COC(=O)c1ccsc1NC(=O)CCS(=O)(=O)c1ccc(Cl)cc1
c.) COc1ccc(OCC(=O)N2CCN(S(=O)(=O)c3ccc(Cl)s3)CC2)cc1
d.) CN(CC(=O)Nc1c(Cl)cccc1Cl)C(=O)c1n[nH]c2ccccc12
e.) O=[N+]([O-])c1ccccc1-c1ccc(CN2CCN(c3ccccc3)CC2)o1
Answer: c. COc1ccc(OCC(=O)N2CCN(S(=O)(=O)c3ccc(Cl)s3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OCC(=O)N2CCN(S(=O)(=O)c3ccc(Cl)s3)CC2)cc1
COc1ccc(OCC(=O)N2CCN(S(=O)(=O)c3ccc(Cl)s3)CC2)cc1
1-[4-(5-chlorothiophen-2-yl)sulfonylpiperazin-1-yl]-2-(4-methoxyphenoxy)ethanone