Problem statement: Answer the MCQ question.
Question: Which compound has a -8.452% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O=C(c1cccc(C(F)(F)F)c1)C1CCCN(C(=O)CCn2cnnn2)C1
[b] CCCOc1ccc(C(CC(=O)O)NS(=O)(=O)c2ccc(NC(C)=O)cc2)cc1
[c] CC1CCOC2(O1)C(=O)Nc1ccccc12
[d] CC(C)(C)c1cc(C(F)(F)F)n2ncc(-c3ccccc3)c2n1
[e] CCOc1cc(N2CCOCC2)c(OCC)cc1NC(=O)c1cccc(N(C)C)c1
Answer: a. O=C(c1cccc(C(F)(F)F)c1)C1CCCN(C(=O)CCn2cnnn2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1cccc(C(F)(F)F)c1)C1CCCN(C(=O)CCn2cnnn2)C1
O=C(c1cccc(C(F)(F)F)c1)C1CCCN(C(=O)CCn2cnnn2)C1
3-(tetrazol-1-yl)-1-[3-[3-(trifluoromethyl)benzoyl]piperidin-1-yl]propan-1-one