Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -1.566% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Cc1noc(C)c1COc1ccc(C(=O)OCC(=O)NC2CCCCC2C)cc1
(b) COC(=O)c1cn(NC(=O)c2ccc(OC)c([N+](=O)[O-])c2)c(=O)c2ccccc12
(c) Cc1cc(SCC(=O)N/N=C/c2ccccc2C(=O)O)c(C)cc1Br
(d) CCCCCCCCCCSc1n[nH]c(N)n1
(e) COc1ccc(S(=O)(=O)NCCc2nnc3ccc(SCc4cccnc4)nn23)cc1
Answer: a. Cc1noc(C)c1COc1ccc(C(=O)OCC(=O)NC2CCCCC2C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1noc(C)c1COc1ccc(C(=O)OCC(=O)NC2CCCCC2C)cc1
Cc1noc(C)c1COc1ccc(C(=O)OCC(=O)NC2CCCCC2C)cc1
[2-oxo-2-[(2-methylcyclohexyl)amino]ethyl]4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]benzoate