Problem statement: Answer the MCQ question.
Question: Which drug has a -11.986% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1cc(=O)oc2cc(NC(=O)c3ccccc3OC(F)F)ccc12
b) O=C(Cc1ccc(Cl)cc1)NCCc1c[nH]c2ccccc12
c) COc1cc(CNn2cn[nH]c2=S)ccc1OCC(=O)NC(C)(C)C
d) Cc1ccnc(N2CCC(C(=O)NCc3ccc(F)cc3)CC2)n1
e) Cn1c(=O)oc2cc(S(=O)(=O)N3CCN(C(=O)c4ccco4)CC3)ccc21
Answer: d. Cc1ccnc(N2CCC(C(=O)NCc3ccc(F)cc3)CC2)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccnc(N2CCC(C(=O)NCc3ccc(F)cc3)CC2)n1
Cc1ccnc(N2CCC(C(=O)NCc3ccc(F)cc3)CC2)n1
N-[(4-fluorophenyl)methyl]-1-(4-methylpyrimidin-2-yl)piperidine-4-carboxamide