Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -5.736% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(Nc1cccc2ccccc12)N1CCc2ccccc2C1
b.) Cc1ccc(OCCCC(=O)Nc2ccc3c(c2)OCCO3)cc1
c.) CCOc1ccc(NC(=O)CC2NCCNC2=O)cc1
d.) COC(=O)C1=C(c2ccc3ccccc3c2)C[C@@H]2CC[C@H]1N2C(=O)NC1CCCCC1
e.) CSCCC(NC(=O)c1ccco1)C(=O)Nc1ccncc1
Answer: d. COC(=O)C1=C(c2ccc3ccccc3c2)C[C@@H]2CC[C@H]1N2C(=O)NC1CCCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc3ccccc3c2)C[C@@H]2CC[C@H]1N2C(=O)NC1CCCCC1
COC(=O)C1=C(c2ccc3ccccc3c2)C[C@@H]2CC[C@H]1N2C(=O)NC1CCCCC1
methyl (1R,5S)-8-(cyclohexylcarbamoyl)-3-naphthalen-2-yl-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate