Problem statement: Answer the multiple-choice question.
Question: Which compound has a -19.052% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C1[C@H]2[C@H](C=CC[C@H]2C(=O)N2CCN(c3ccccc3)CC2)CCN1Cc1ccc(Cl)c(Cl)c1
(b) O=C(NCCCNC(=O)c1ccccc1)c1ccccc1
(c) CCc1ccc2[nH]c(=O)c(C(c3nnnn3Cc3ccc(OC)cc3)N3CCOCC3)cc2c1
(d) CN(CC(=O)Nc1ccccc1Cl)CC(=O)c1c(N)n(Cc2ccccc2)c(=O)n(C)c1=O
(e) COC(=O)c1ccc(CSc2nc3ccc(S(N)(=O)=O)cc3[nH]2)cc1
Answer: c. CCc1ccc2[nH]c(=O)c(C(c3nnnn3Cc3ccc(OC)cc3)N3CCOCC3)cc2c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1ccc2[nH]c(=O)c(C(c3nnnn3Cc3ccc(OC)cc3)N3CCOCC3)cc2c1
CCc1ccc2[nH]c(=O)c(C(c3nnnn3Cc3ccc(OC)cc3)N3CCOCC3)cc2c1
6-ethyl-3-[[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]-morpholin-4-ylmethyl]-1H-quinolin-2-one