Problem statement: Answer the multiple choice question.
Query: Which compound has a 11.499% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=S(=O)(N1CCOCC1)N1CCN(c2ccc(F)cc2)CC1
(b) COc1ccc(CNC(=O)C2=C(C)C(=O)OC23CCC(C)CC3)cc1
(c) COc1ccc2[nH]c3c(c2c1)CCN1C(=O)N([C@@H](C)C(=O)NCCc2ccc(F)cc2)C(=O)[C@]31C
(d) COC1CCN(C(=O)c2cc(COc3ccc(-n4cncn4)cc3)on2)CC1
(e) CCO/C=C1\C(=O)N(c2ccc(OCC)cc2)C(=O)c2ccccc21
Answer: b. COc1ccc(CNC(=O)C2=C(C)C(=O)OC23CCC(C)CC3)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C2=C(C)C(=O)OC23CCC(C)CC3)cc1
COc1ccc(CNC(=O)C2=C(C)C(=O)OC23CCC(C)CC3)cc1
N-[(4-methoxyphenyl)methyl]-3,8-dimethyl-2-oxo-1-oxaspiro[4.5]dec-3-ene-4-carboxamide