Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -9.785% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1cc(CN2CCC(C(=O)NC3CCCC3)CC2)ccc1O.O=C(O)C(=O)O
b.) COc1cccc(CNS(=O)(=O)c2ccc(S(=O)(=O)NC3CC3)cc2)c1
c.) Cn1cccc1C(=O)NC(=O)COC(=O)CC12CC3CC(CC(C3)C1)C2
d.) O=C(OCC(=O)N1CCCC1=O)c1cc2ccccc2o1
e.) Cc1ccc(N2C(=O)CC(N(O)C3CC(=O)N(c4ccc(C)cc4)C3=O)C2=O)cc1
Answer: e. Cc1ccc(N2C(=O)CC(N(O)C3CC(=O)N(c4ccc(C)cc4)C3=O)C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(N2C(=O)CC(N(O)C3CC(=O)N(c4ccc(C)cc4)C3=O)C2=O)cc1
Cc1ccc(N2C(=O)CC(N(O)C3CC(=O)N(c4ccc(C)cc4)C3=O)C2=O)cc1
3-[hydroxy-[1-(4-methylphenyl)-2,5-dioxopyrrolidin-3-yl]amino]-1-(4-methylphenyl)pyrrolidine-2,5-dione