Problem statement: Answer the MCQ question.
Query: Which drug has a 15.340% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccc(/C=N/NC(=O)CN(c2ccc(OC)cc2)S(=O)(=O)c2ccccc2)cc1
b. N#Cc1c(SCC(=O)Nc2ccccc2C(F)(F)F)sc2c(O)cc(=O)[nH]c12
c. COC(=O)C1CCN(C(=O)c2ccc(OC3CCN(Cc4ccccn4)CC3)cc2)CC1
d. S=c1[nH]nc(-c2cc(-c3ccco3)[nH]n2)n1-c1ccccc1
e. COc1ccccc1N1CCN(S(=O)(=O)c2cc(Br)cnc2N)CC1
Answer: c. COC(=O)C1CCN(C(=O)c2ccc(OC3CCN(Cc4ccccn4)CC3)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1CCN(C(=O)c2ccc(OC3CCN(Cc4ccccn4)CC3)cc2)CC1
COC(=O)C1CCN(C(=O)c2ccc(OC3CCN(Cc4ccccn4)CC3)cc2)CC1
methyl 1-[4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]oxybenzoyl]piperidine-4-carboxylate