Problem statement: Answer the multiple-choice question.
Question: Which drug has a -5.790% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1ccc(CN(C(=O)c2csnn2)C(C(=O)NC2CCCC2)c2ccccn2)cc1
b COCCCNC(=O)CCc1c(C)c2cc3c(C)coc3cc2oc1=O
c COc1ccc(C[C@H]2CN3C(=NC[C@@H]3C(C)C)N2C[C@H](C)NC(=O)c2ccc(C)c(Br)c2)cc1
d CCOC(=O)N1CCN(C(=S)NC(=O)c2ccc(F)cc2)CC1
e COc1nsnc1NS(=O)(=O)c1ccc(NC(=S)NC(=O)c2ccncc2)cc1
Answer: b. COCCCNC(=O)CCc1c(C)c2cc3c(C)coc3cc2oc1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCCNC(=O)CCc1c(C)c2cc3c(C)coc3cc2oc1=O
COCCCNC(=O)CCc1c(C)c2cc3c(C)coc3cc2oc1=O
3-(3,5-dimethyl-7-oxofuro[3,2-g]chromen-6-yl)-N-(3-methoxypropyl)propanamide