Task: Answer the multiple-choice question.
Query: Which compound has a -22.500% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1ccc(CNS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)cc2)o1
b) O=C(NCC1CCCCC1)c1cc(S(=O)(=O)N2CCOCC2)ccc1F
c) COc1ccc(N2CCN(C(CNS(=O)(=O)c3ccccc3)c3ccccc3)CC2)cc1
d) COc1cc(NC(=O)CCC2CCCC2)cc(-n2cnnn2)c1
e) Cc1csc(N(C(=O)Cc2ccccc2F)c2ccccc2)n1
Answer: c. COc1ccc(N2CCN(C(CNS(=O)(=O)c3ccccc3)c3ccccc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(C(CNS(=O)(=O)c3ccccc3)c3ccccc3)CC2)cc1
COc1ccc(N2CCN(C(CNS(=O)(=O)c3ccccc3)c3ccccc3)CC2)cc1
N-[2-[4-(4-methoxyphenyl)-1,4-diazinan-1-yl]-2-phenylethyl]benzenesulfonamide