Problem statement: Answer the MCQ question.
Question: Which compound has a -13.050% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] CCOc1ccc(N2CC(C(=O)N3CCc4ccccc43)CC2=O)cc1
[b] COc1ccc(Br)cc1CN(C)CC(=O)Nc1ccccc1Cl
[c] COc1ccc(NC(C)=O)cc1S(=O)(=O)NC(Cc1ccccc1)C(=O)NCc1ccccc1C
[d] COc1ccc(NC(=O)COc2ccccc2F)cc1S(=O)(=O)N1CCCCC1
Answer: c. COc1ccc(NC(C)=O)cc1S(=O)(=O)NC(Cc1ccccc1)C(=O)NCc1ccccc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(C)=O)cc1S(=O)(=O)NC(Cc1ccccc1)C(=O)NCc1ccccc1C
COc1ccc(NC(C)=O)cc1S(=O)(=O)NC(Cc1ccccc1)C(=O)NCc1ccccc1C
2-[(5-acetamido-2-methoxyphenyl)sulfonylamino]-N-[(2-methylphenyl)methyl]-3-phenylpropanamide