Problem statement: Answer the multiple-choice question.
Query: Which drug has a -24.169% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a O=C(Nc1ccccc1Cl)C1CCCN1C(=O)OCc1ccccc1
b O=C(c1ccco1)N1CCN(S(=O)(=O)c2ccc3c(c2)CCN3C(=O)C2CCC2)CC1
c C=CCc1ccc(OCC(O)CN2CCCCC2)c(OC)c1
d CCCCCN(C(=O)CCC(=O)OCC(=O)N(CC)C1CCCCC1)c1c(N)n(CCCC)c(=O)[nH]c1=O
Answer: b. O=C(c1ccco1)N1CCN(S(=O)(=O)c2ccc3c(c2)CCN3C(=O)C2CCC2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccco1)N1CCN(S(=O)(=O)c2ccc3c(c2)CCN3C(=O)C2CCC2)CC1
O=C(c1ccco1)N1CCN(S(=O)(=O)c2ccc3c(c2)CCN3C(=O)C2CCC2)CC1
cyclobutyl-[5-[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]methanone