Problem statement: Answer the multiple choice question.
Question: Which compound has a -80.780% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(-n2cnnc2SCC(=O)Nc2cccc(S(N)(=O)=O)c2)cc1
b) O=C(c1cc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2)n1)N1CCOCC1
c) c1ccc(-n2cc(CNCCc3cscn3)c(-c3ccc4c(c3)OCO4)n2)cc1
d) COc1c(F)c(F)c(C(=O)O)c(Nc2ccc(C)cc2)c1F
e) CCN(CC)CCNC(=O)C(=O)NCC1OCCN1S(=O)(=O)c1ccc([N+](=O)[O-])cc1
Answer: b. O=C(c1cc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2)n1)N1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1cc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2)n1)N1CCOCC1
O=C(c1cc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2)n1)N1CCOCC1
[1,5-bis(4-chlorophenyl)pyrazol-3-yl]-morpholin-4-ylmethanone