Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -77.961% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1c(NC(=O)c2ccc(S(=O)(=O)N3CCOCC3)cc2)cccc1[N+](=O)[O-]
b C=CCn1c(CCCNC(=O)c2ccccc2OC)nc2ccccc21
c COc1ccc(-c2noc(CNC(=O)C(C)Oc3ccccc3)n2)cc1
d COc1ccc(CN2CCCC(C(=O)c3ccc(Cl)cc3)C2)cc1Cn1cncn1
e CCOc1ccc(N(CC(=O)NCCc2ccccc2)C(=O)c2csnn2)cc1
Answer: d. COc1ccc(CN2CCCC(C(=O)c3ccc(Cl)cc3)C2)cc1Cn1cncn1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CN2CCCC(C(=O)c3ccc(Cl)cc3)C2)cc1Cn1cncn1
COc1ccc(CN2CCCC(C(=O)c3ccc(Cl)cc3)C2)cc1Cn1cncn1
(4-chlorophenyl)-[1-[[4-methoxy-3-(1,2,4-triazol-1-ylmethyl)phenyl]methyl]piperidin-3-yl]methanone