Problem statement: Answer the multiple-choice question.
Question: Which drug has a -1.091% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a COc1ccc(-c2oc3ncn(CCN4CCOCC4)c(=N)c3c2-c2ccc(OC)cc2)cc1
b COc1ccc2c(c1)O[C@@]1(CCCC[C@@H]1C)CC2=O
c COc1ccc(NS(=O)(=O)c2ccc(N3CCOCC3)c(NC(=O)c3ccccc3Br)c2)cc1
Answer: b. COc1ccc2c(c1)O[C@@]1(CCCC[C@@H]1C)CC2=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2c(c1)O[C@@]1(CCCC[C@@H]1C)CC2=O
COc1ccc2c(c1)O[C@@]1(CCCC[C@@H]1C)CC2=O
(2S,2'S)-7-methoxy-2'-methylspiro[3H-chromene-2,1'-cyclohexane]-4-one