Problem statement: Answer the multiple choice question.
Query: Which compound has a 10.223% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccc(-[n+]2c(C)cc(/C=C3\Sc4ccccc4N3C)cc2C)cc1.[I-]
b: CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CN(Cc3ccc(F)cc3)C(=O)[C@@]12C
c: CCC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)c1csnn1)c1ccccc1
d: O=C(COc1ccc([N+](=O)[O-])cc1)NNC(=O)c1cccs1
e: O=C(N[C@H]1CCCCNC1=O)c1cc(COc2ccc(F)cc2F)on1
Answer: e. O=C(N[C@H]1CCCCNC1=O)c1cc(COc2ccc(F)cc2F)on1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(N[C@H]1CCCCNC1=O)c1cc(COc2ccc(F)cc2F)on1
O=C(N[C@H]1CCCCNC1=O)c1cc(COc2ccc(F)cc2F)on1
5-[(2,4-difluorophenoxy)methyl]-N-[(3S)-2-oxoazepan-3-yl]-1,2-oxazole-3-carboxamide