Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 7.995% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1ccccc1N1CCN(C2CCCN(S(=O)(=O)c3ccccc3)C2)CC1
b: O=C(COC(=O)CCNS(=O)(=O)c1ccc(Cl)cc1)NCc1ccco1
c: C=CCNC(=S)Nc1nc2c(cc1C(=O)OCC)COC(C)(C)C2
d: CC1C(=O)Nc2ccc(S(=O)(=O)N3CCN(c4ccccc4F)CC3)cc2NC1=O
e: C=CCn1c(O)c(C=NCCN2CCNCC2)c(=O)[nH]c1=O
Answer: c. C=CCNC(=S)Nc1nc2c(cc1C(=O)OCC)COC(C)(C)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C=CCNC(=S)Nc1nc2c(cc1C(=O)OCC)COC(C)(C)C2
C=CCNC(=S)Nc1nc2c(cc1C(=O)OCC)COC(C)(C)C2
ethyl 7,7-dimethyl-2-(prop-2-enylcarbamothioylamino)-5,8-dihydropyrano[4,3-b]pyridine-3-carboxylate