Problem statement: Answer the MCQ question.
Query: Which compound has a -21.780% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1cc(NC(=O)c2ccccc2OCc2ccccc2)cc(OC)c1OC
b) O=C(NCCSc1ncc(-c2ccc(F)cc2)[nH]1)c1ccco1
c) COc1ccc(CNC(=O)C2=CC(c3ccc(OC)c(OC)c3)=NS(=O)(=O)N2C)cc1
d) COc1ccccc1CNS(=O)(=O)CCNC(=O)c1ccccc1
e) O=C1c2cccc3cccc(c23)C(=O)N1CCCCCc1n[nH]c(=S)o1
Answer: c. COc1ccc(CNC(=O)C2=CC(c3ccc(OC)c(OC)c3)=NS(=O)(=O)N2C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C2=CC(c3ccc(OC)c(OC)c3)=NS(=O)(=O)N2C)cc1
COc1ccc(CNC(=O)C2=CC(c3ccc(OC)c(OC)c3)=NS(=O)(=O)N2C)cc1
5-(3,4-dimethoxyphenyl)-N-[(4-methoxyphenyl)methyl]-2-methyl-1,1-dioxo-1,2,6-thiadiazine-3-carboxamide