Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -8.740% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1cccc(NS(=O)(=O)c2ccc3c(c2)NC(=O)C(C)S3)c1
[b] Cc1ccsc1/C=C1\SC(=S)N(CC2CCCO2)C1=O
[c] COc1ccc(CCNC(=O)Cc2c(Cl)cccc2Cl)cc1
[d] O=C(CN1C(=O)C2CCCCC2C1=O)N1CCN(c2ccccc2)CC1
[e] Cc1nonc1CC(=O)N1CCCC(C(=O)c2ccc(Cl)cc2)C1
Answer: a. COc1cccc(NS(=O)(=O)c2ccc3c(c2)NC(=O)C(C)S3)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(NS(=O)(=O)c2ccc3c(c2)NC(=O)C(C)S3)c1
COc1cccc(NS(=O)(=O)c2ccc3c(c2)NC(=O)C(C)S3)c1
N-(3-methoxyphenyl)-2-methyl-3-oxo-4H-1,4-benzothiazine-6-sulfonamide