Problem statement: Answer the MCQ question.
Question: Which drug has a 8.675% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(CN2CC(=O)N3[C@H]4c5ccc(OC)cc5OC[C@@H]4[C@H](c4ccccc4)[C@]3(C)C2=O)cc1
b. CN(C)CCCN(C(=O)c1ccc(Br)s1)c1nc2cc3c(cc2s1)OCO3.Cl
c. COCCNC(=O)CSc1nc2nc(C)cc(C)n2n1
d. CC1CCc2c(sc(NC(=S)NC(=O)c3ccccc3)c2C#N)C1
e. O=C(CC(C(=O)O)c1cccc(Cl)c1)c1ccccc1
Answer: a. COc1ccc(CN2CC(=O)N3[C@H]4c5ccc(OC)cc5OC[C@@H]4[C@H](c4ccccc4)[C@]3(C)C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CN2CC(=O)N3[C@H]4c5ccc(OC)cc5OC[C@@H]4[C@H](c4ccccc4)[C@]3(C)C2=O)cc1
COc1ccc(CN2CC(=O)N3[C@H]4c5ccc(OC)cc5OC[C@@H]4[C@H](c4ccccc4)[C@]3(C)C2=O)cc1
(1R,10R,11R,12R)-5-methoxy-14-[(4-methoxyphenyl)methyl]-12-methyl-11-phenyl-8-oxa-14,17-diazatetracyclo[8.7.0.02,7.012,17]heptadeca-2(7),3,5-triene-13,16-dione