Problem statement: Answer the MCQ question.
Question: Which drug has a 12.295% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
(a) O=C1NC(=O)N(c2ccc(F)cc2)C(=O)/C1=C/c1ccsc1
(b) COC(=O)Cc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1
(c) COc1ccc(N(C(C)C(=O)Nc2ccc(S(=O)(=O)N3CCCCC3)cc2)S(C)(=O)=O)cc1
Answer: b. COC(=O)Cc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)Cc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1
COC(=O)Cc1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1
methyl2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxyphenyl]acetate