Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -21.143% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C1CCc2cc(S(=O)(=O)NC(C(=O)NCc3cccnc3)c3ccccc3)ccc2N1
(b) COc1cccc(C2CC(C(F)(F)F)n3nc(C(=O)NCc4cccnc4)cc3N2)c1
(c) CN(CCC#N)C(=O)COC(=O)/C=C/c1cccs1
(d) COc1cc([N+](=O)[O-])ccc1NC(=O)CSc1nnc(C)c(C)n1
(e) CCOC(=O)c1sc(=NC(=O)c2ccc(OC)c(OC)c2)n(C)c1C
Answer: b. COc1cccc(C2CC(C(F)(F)F)n3nc(C(=O)NCc4cccnc4)cc3N2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(C2CC(C(F)(F)F)n3nc(C(=O)NCc4cccnc4)cc3N2)c1
COc1cccc(C2CC(C(F)(F)F)n3nc(C(=O)NCc4cccnc4)cc3N2)c1
5-(3-methoxyphenyl)-N-(pyridin-3-ylmethyl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide