Problem statement: Answer the MCQ question.
Query: Which compound has a -4.865% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COCCn1c(SCc2nnc(-c3ccc(OC)c(OC)c3)o2)nnc1-c1ccncc1
b. Cc1c(C#N)c(O)n(CCO)c(=O)c1N=Nc1ccc(S(N)(=O)=O)cc1
c. O=C(Cc1cccs1)Nc1ccc(-c2nnc(-c3ccccc3)o2)cc1
d. C#CCOCCOCCOCCNc1nc(N2CCN(C(=O)CCCCCCCCCCNC(=O)[C@H](CCCCN)n3cc(C)nn3)CC2)nc(N2CCN(C(=O)CCCCCCCCCCNC(=O)[C@H](CCCCN)n3cc(CCCC(=O)O)nn3)CC2)n1
e. CCO[C@@H]1OC(C(=O)N2CCN(C)CC2)=C[C@H](c2csc3ccccc23)[C@H]1CCCO
Answer: e. CCO[C@@H]1OC(C(=O)N2CCN(C)CC2)=C[C@H](c2csc3ccccc23)[C@H]1CCCO
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCO[C@@H]1OC(C(=O)N2CCN(C)CC2)=C[C@H](c2csc3ccccc23)[C@H]1CCCO
CCO[C@@H]1OC(C(=O)N2CCN(C)CC2)=C[C@H](c2csc3ccccc23)[C@H]1CCCO
[(2R,3R,4S)-4-(1-benzothiophen-3-yl)-2-ethoxy-3-(3-hydroxypropyl)-3,4-dihydro-2H-pyran-6-yl]-(4-methylpiperazin-1-yl)methanone