Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -1.222% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CC(=O)Oc1ccc(/C=C(\NC(=O)c2cccc(Br)c2)C(=O)Nc2ccc(C(=O)O)cc2)cc1
[b] CCOc1ccc2c(c1)c1nnc(SCC(=O)N3CCCCC3C)nc1n2C
[c] N#CC(C(=O)Nc1ccccc1)=C1Nc2ccccc2N1
[d] CCc1ccccc1-n1c(SCC(=O)NC)nnc1-c1ccco1
[e] CC(=O)N1c2ccc(S(=O)(=O)N3CCC(C(=O)NC4CCCC(C)C4C)CC3)cc2CC1C
Answer: e. CC(=O)N1c2ccc(S(=O)(=O)N3CCC(C(=O)NC4CCCC(C)C4C)CC3)cc2CC1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=O)N1c2ccc(S(=O)(=O)N3CCC(C(=O)NC4CCCC(C)C4C)CC3)cc2CC1C
CC(=O)N1c2ccc(S(=O)(=O)N3CCC(C(=O)NC4CCCC(C)C4C)CC3)cc2CC1C
1-[(1-acetyl-2-methyl-2,3-dihydroindol-5-yl)sulfonyl]-N-(2,3-dimethylcyclohexyl)piperidine-4-carboxamide