Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -54.748% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccc(OC)c(-c2cc(C3CCN(C(=O)OC(C)(C)C)CC3)[nH]n2)c1
b. COc1ccc(S(=O)(=O)N2CC(O)CC2C(=O)Nc2cccnc2)cc1
c. C=Cc1ccc(C2=CC(=O)C[C@H](c3ccc(OC)cc3)C2)cc1
d. Cc1cc(C)n(CCCNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)n1
e. Cc1ccc(Cn2nnc3c(=O)[nH]c(C4CCN(S(=O)(=O)c5ccccc5F)CC4)nc32)cc1
Answer: d. Cc1cc(C)n(CCCNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cc(C)n(CCCNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)n1
Cc1cc(C)n(CCCNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)n1
1-[2-(4-chlorophenyl)ethyl]-N-[3-(3,5-dimethylpyrazol-1-yl)propyl]-6-oxopiperidine-3-carboxamide