Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -8.622% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1cccc(NC(=O)C2CCN(S(=O)(=O)c3ccc4[nH]c(=O)oc4c3)CC2)c1
b) CCc1noc(C)c1C(=O)N(C)CC(=O)Nc1ccc(OC)cc1
c) COc1ccc(NC(=O)COc2cccc3c2CCN(Cc2cccnc2)C3=O)c(OC)c1
d) COc1ccc(CC(=O)NC(=S)Nc2cccc(C)c2)cc1
e) Cc1cccc(N2CCN(C(=O)NC3CCCCC3)CC2)c1C
Answer: c. COc1ccc(NC(=O)COc2cccc3c2CCN(Cc2cccnc2)C3=O)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)COc2cccc3c2CCN(Cc2cccnc2)C3=O)c(OC)c1
COc1ccc(NC(=O)COc2cccc3c2CCN(Cc2cccnc2)C3=O)c(OC)c1
N-(2,4-dimethoxyphenyl)-2-[[1-oxo-2-(pyridin-3-ylmethyl)-3,4-dihydroisoquinolin-5-yl]oxy]acetamide