Problem statement: Answer the multiple choice question.
Query: Which compound has a -8.823% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(c1ccccc1)[C@@H]1[C@@H](C(=O)c2ccc(F)cc2)[C@@]2(C(=O)Nc3ccccc32)[C@H]2c3ccccc3C=CN12
b.) Cc1cccc(-n2ncc3c2CCCC3NC(=O)Cn2cccn2)c1C
c.) CC1CC(=S)Nc2ccccc2N1Cc1ccccc1
d.) COc1ccc(C2=NN(C(=O)CSc3ncccn3)C(c3cccc(OC)c3OC)C2)cc1
e.) CCCNC(=O)c1ccc(N2CCC3(CC2)CC(c2ccccc2)=NO3)c(NC(=O)c2ccc(Br)cc2)c1
Answer: d. COc1ccc(C2=NN(C(=O)CSc3ncccn3)C(c3cccc(OC)c3OC)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2=NN(C(=O)CSc3ncccn3)C(c3cccc(OC)c3OC)C2)cc1
COc1ccc(C2=NN(C(=O)CSc3ncccn3)C(c3cccc(OC)c3OC)C2)cc1
1-[3-(2,3-dimethoxyphenyl)-5-(4-methoxyphenyl)-3,4-dihydropyrazol-2-yl]-2-pyrimidin-2-ylsulfanylethanone