Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -11.350% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CC[C@H]1CC2CN3CCc4c([nH]c5ccccc45)C(C(=O)OC)(C2)C13.Cl
b. CCOC(=O)CCNCc1ccc(F)cc1.Cl
c. CC(C)CN(C(=O)c1ccc(S(=O)(=O)N2CCCC2)cc1)C1CCS(=O)(=O)C1
d. CC(=O)Nc1ccc(NC(=O)c2nc(S(=O)(=O)Cc3cccc(C)c3)ncc2Cl)cc1
e. O=C1C=C(c2ccc(OC(F)(F)F)cc2)C[C@@H](c2ccc(F)cc2)C1
Answer: e. O=C1C=C(c2ccc(OC(F)(F)F)cc2)C[C@@H](c2ccc(F)cc2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1C=C(c2ccc(OC(F)(F)F)cc2)C[C@@H](c2ccc(F)cc2)C1
O=C1C=C(c2ccc(OC(F)(F)F)cc2)C[C@@H](c2ccc(F)cc2)C1
(5R)-5-(4-fluorophenyl)-3-[4-(trifluoromethoxy)phenyl]cyclohex-2-en-1-one