Problem statement: Answer the multiple-choice question.
Query: Which compound has a -12.047% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C1CC(NS(=O)(=O)c2cccnc2)CN1c1ccc(Cl)cc1
b. O=C(NCc1ccco1)c1ccc(NS(=O)(=O)c2cccc([N+](=O)[O-])c2)cc1
c. Cc1noc(C(=O)Nc2cc(Cl)ccc2O)c1Cl
d. CCN(CC(=O)NCCc1ccc(S(N)(=O)=O)cc1)Cc1ccccc1
e. COC(=O)[C@@]12CCCCN1[C@H](c1ccc(-c3cccc(Cl)c3)cc1)[C@H]1C(=O)N(C)C(=O)[C@H]12.O=C(O)C(F)(F)F
Answer: a. O=C1CC(NS(=O)(=O)c2cccnc2)CN1c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1CC(NS(=O)(=O)c2cccnc2)CN1c1ccc(Cl)cc1
O=C1CC(NS(=O)(=O)c2cccnc2)CN1c1ccc(Cl)cc1
N-[1-(4-chlorophenyl)-5-oxopyrrolidin-3-yl]pyridine-3-sulfonamide