Problem statement: Answer the MCQ question.
Question: Which drug has a -23.731% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(C)cc1NC(=O)C1CCCN(S(=O)(=O)c2cccc3nonc23)C1
b) CCCCNc1nc2ccccc2[nH]1
c) Cc1ccc(S(=O)(=O)N[C@H](C(=O)N2CCC(C(=O)NCC(=O)O)CC2)C(C)C)cc1
d) CCOc1ccc(S(=O)(=O)NCCC(=O)N2CCCC(C)C2)cc1
e) CCNc1c(NS(=O)(=O)c2ccc(Br)s2)c(=O)oc2ccccc12
Answer: d. CCOc1ccc(S(=O)(=O)NCCC(=O)N2CCCC(C)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(S(=O)(=O)NCCC(=O)N2CCCC(C)C2)cc1
CCOc1ccc(S(=O)(=O)NCCC(=O)N2CCCC(C)C2)cc1
4-ethoxy-N-[3-(3-methylpiperidin-1-yl)-3-oxopropyl]benzenesulfonamide