Problem statement: Answer the multiple-choice question.
Question: Which compound has a -13.533% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C(Nc1cccc(Cl)c1)c1ccc(F)c(S(=O)(=O)N2CCN(c3ccccn3)CC2)c1
(b) COc1ccc(NC(=O)CNC(=O)C23CC4CC(CC(C4)C2)C3)c(OC)c1
(c) CCn1c(CCNC(=O)c2ccc(OC)cc2)nnc1SCc1ccc(Cl)c(Cl)c1
(d) CCOc1ccc(N2CC(C(=O)N3CCCC3)CC2=O)cc1
(e) c1ccc2[nH]c(CN3CCN(c4ncnc5c4oc4ccccc45)CC3)nc2c1
Answer: b. COc1ccc(NC(=O)CNC(=O)C23CC4CC(CC(C4)C2)C3)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)CNC(=O)C23CC4CC(CC(C4)C2)C3)c(OC)c1
COc1ccc(NC(=O)CNC(=O)C23CC4CC(CC(C4)C2)C3)c(OC)c1
N-[2-(2,4-dimethoxyanilino)-2-oxoethyl]adamantane-1-carboxamide