Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -31.582% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CC(C)NC(=O)COc1coc(CN2CCN(C(=O)c3ccco3)CC2)cc1=O
b. COc1ccc(N=CC=C2OC(C)(C)C(C)(C)O2)cc1OC.Cl
c. CCOc1ccc(CN(C(=O)/C=C/c2ccco2)C2CCS(=O)(=O)C2)cc1
d. Cc1[nH]c2ccccc2c1C(c1ccncc1)N1CCN(c2ccccn2)CC1
e. CCS(=O)(=O)N1Cc2ccccc2CC1C(=O)N(C)CC(=O)Nc1ccc(OC)cc1
Answer: c. CCOc1ccc(CN(C(=O)/C=C/c2ccco2)C2CCS(=O)(=O)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(CN(C(=O)/C=C/c2ccco2)C2CCS(=O)(=O)C2)cc1
CCOc1ccc(CN(C(=O)/C=C/c2ccco2)C2CCS(=O)(=O)C2)cc1
(E)-N-(1,1-dioxothiolan-3-yl)-N-[(4-ethoxyphenyl)methyl]-3-(furan-2-yl)prop-2-enamide