Problem statement: Answer the multiple-choice question.
Question: Which drug has a -3.541% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C1CCc2cc(S(=O)(=O)NC(Cc3ccccc3)C(=O)N3CCN(c4ccccn4)CC3)ccc2N1
b) CCNC(=O)/C=C1\NC(C)(C)Cc2c1ccc1ccccc21
c) COC(=O)c1c(C)[nH]c(C(=O)C(C)OC(=O)c2ccco2)c1C
d) CCOC(=O)N1CCN(S(=O)(=O)N2CCCC(C(=O)NCCc3ccc(OCC)c(OCC)c3)C2)CC1
e) CC(C)C(=O)Nc1ccc(NC(=S)NC(=O)c2ccccc2F)cc1
Answer: a. O=C1CCc2cc(S(=O)(=O)NC(Cc3ccccc3)C(=O)N3CCN(c4ccccn4)CC3)ccc2N1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1CCc2cc(S(=O)(=O)NC(Cc3ccccc3)C(=O)N3CCN(c4ccccn4)CC3)ccc2N1
O=C1CCc2cc(S(=O)(=O)NC(Cc3ccccc3)C(=O)N3CCN(c4ccccn4)CC3)ccc2N1
2-oxo-N-[1-oxo-3-phenyl-1-(1-pyridin-2-ylpiperazin-4-yl)propan-2-yl]-3,4-dihydro-1H-quinoline-6-sulfonamide