Problem statement: Answer the MCQ question.
Query: Which drug has a -13.357% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
(a) O=S(=O)(NC1CC2CCC1C2)c1ccc(Br)s1
(b) N#C/C(=C\c1cccs1)Sc1nc2ccccc2s1
(c) Cc1cccc(N2CCN(C(=O)c3ccc4c(c3)NC(=O)C(CSCc3ccc(F)cc3)N4)CC2C)c1
(d) Cc1cnc(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)cn1
Answer: d. Cc1cnc(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)cn1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cnc(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)cn1
Cc1cnc(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)cn1
(5-methylpyrazin-2-yl)-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone