Problem statement: Answer the multiple-choice question.
Question: Which drug has a -8.372% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(-c2cc(-c3cccnc3)c(C#N)c(N)n2)cc1
b. COc1ccc(C)c2sc(NC(=O)CCS(=O)(=O)c3ccccc3)nc12
c. Cc1cc(C)cc(NC(=S)NCCSc2ccc(Cl)cc2)c1
d. Cc1ccc(S(=O)(=O)CCC(=O)OCC(=O)N(CCC#N)c2cc(C)cc(C)c2)cc1
e. CC(Sc1nccn1C)C(=O)Nc1ccc(C(N)=O)cc1
Answer: d. Cc1ccc(S(=O)(=O)CCC(=O)OCC(=O)N(CCC#N)c2cc(C)cc(C)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)CCC(=O)OCC(=O)N(CCC#N)c2cc(C)cc(C)c2)cc1
Cc1ccc(S(=O)(=O)CCC(=O)OCC(=O)N(CCC#N)c2cc(C)cc(C)c2)cc1
[2-[N-(2-cyanoethyl)-3,5-dimethylanilino]-2-oxoethyl] 3-(4-methylphenyl)sulfonylpropanoate