Problem statement: Answer the multiple-choice question.
Question: Which drug has a -15.931% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCN(CC)S(=O)(=O)c1ccc(C(=O)NNc2nc(-c3ccccc3)c3cc(Br)ccc3n2)cc1
(b) C=CCNC(=O)/C(=C\c1ccc(Br)cc1)NC(=O)c1ccccc1OC
(c) Cc1sc2ncn(CC(=O)NCCCN3CC(C)CC(C)C3)c(=O)c2c1S(=O)(=O)N1CC(C)CC(C)C1
(d) COc1ccc(-c2cc(CCCC(=O)NCc3ccccn3)no2)cc1
(e) COc1cc(-c2nc(CN3CCCCC3CCNC(C)=O)c(C)o2)ccc1F
Answer: d. COc1ccc(-c2cc(CCCC(=O)NCc3ccccn3)no2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2cc(CCCC(=O)NCc3ccccn3)no2)cc1
COc1ccc(-c2cc(CCCC(=O)NCc3ccccn3)no2)cc1
4-[5-(4-methoxyphenyl)-1,2-oxazol-3-yl]-N-(pyridin-2-ylmethyl)butanamide