Problem statement: Answer the multiple-choice question.
Question: Which drug has a -59.371% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCC1CCc2c(sc(NC(=O)C3c4ccccc4Oc4ccccc43)c2C(N)=O)C1
(b) COC(=O)Cn1c(C)nc([N+](=O)[O-])c1Br
(c) O=C1N(Cc2cccnc2)C[C@@H]2C[C@@H](c3cccc(Oc4ccccc4)c3)N3CCC[C@@]123
(d) CCN(Cc1ccc(OC)c(COC)c1)CC1CCCN(CCc2cccc(F)c2)C1
(e) CCc1cc(=O)[nH]c(SCCCF)n1
Answer: c. O=C1N(Cc2cccnc2)C[C@@H]2C[C@@H](c3cccc(Oc4ccccc4)c3)N3CCC[C@@]123
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1N(Cc2cccnc2)C[C@@H]2C[C@@H](c3cccc(Oc4ccccc4)c3)N3CCC[C@@]123
O=C1N(Cc2cccnc2)C[C@@H]2C[C@@H](c3cccc(Oc4ccccc4)c3)N3CCC[C@@]123
(1S,5S,7S)-7-(3-phenoxyphenyl)-3-(pyridin-3-ylmethyl)-3,8-diazatricyclo[6.3.0.01,5]undecan-2-one