Task: Answer the multiple choice question.
Query: Which drug exhibits a -77.943% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CC1CCC(NC(=O)CNC(=S)N2CC3CC(C2)c2cccc(=O)n2C3)CC1
b: NC(=O)COc1c(-c2ccc(Br)o2)oc2ccccc2c1=O
c: COc1ccc(NC(=O)COC(=O)COc2cccc3c2OC(C)(C)C3)cc1
d: O=C(COc1ccccc1)NS(=O)(=O)c1ccc(Cl)cc1
e: CCOC(=O)C1(Cc2cccc(OC)c2)CCN(Cc2ccc(OC)c(O)c2)CC1
Answer: e. CCOC(=O)C1(Cc2cccc(OC)c2)CCN(Cc2ccc(OC)c(O)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1(Cc2cccc(OC)c2)CCN(Cc2ccc(OC)c(O)c2)CC1
CCOC(=O)C1(Cc2cccc(OC)c2)CCN(Cc2ccc(OC)c(O)c2)CC1
ethyl 1-[(3-hydroxy-4-methoxyphenyl)methyl]-4-[(3-methoxyphenyl)methyl]piperidine-4-carboxylate