Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 10.741% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1ccc(-c2nc(-c3ccccn3)no2)cc1
(b) Cc1nc2c(c(-c3ccccc3)c1C#N)C(=O)c1ccccc1-2
(c) COC(=O)c1ccc(C2NC(=O)c3c(sc(C)c3C)N2)cc1
(d) NC(=O)C1CCN(C(=O)CCC(=O)c2ccc(Br)cc2)CC1
(e) CCOC(=O)c1c(C)[nH]c(C)c1C(=O)CSc1nc2ccccc2c(=O)n1-c1ccc(C)cc1
Answer: c. COC(=O)c1ccc(C2NC(=O)c3c(sc(C)c3C)N2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(C2NC(=O)c3c(sc(C)c3C)N2)cc1
COC(=O)c1ccc(C2NC(=O)c3c(sc(C)c3C)N2)cc1
methyl 4-(5,6-dimethyl-4-oxo-2,3-dihydro-1H-thieno[2,3-d]pyrimidin-2-yl)benzoate