Task: Answer the MCQ question.
Question: Which compound has a -57.052% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1ccc(S(=O)(=O)NCc2cccnc2)cc1C(=O)NC1CCCCC1
[b] O=C(NCC1CCCO1)c1ccc(CS(=O)(=O)c2ccc(Br)cc2)o1
[c] O=C(NCc1cccnc1)C1CC(c2ccccc2Cl)=NO1
[d] COC(=O)C1=CN(CCCN2CCCC2=O)C=C(C(=O)OC)C1c1ccccc1C(F)(F)F
[e] O=C(CSc1ncnc2c1cnn2-c1ccc(F)cc1)NCc1ccc2c(c1)OCO2
Answer: d. COC(=O)C1=CN(CCCN2CCCC2=O)C=C(C(=O)OC)C1c1ccccc1C(F)(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=CN(CCCN2CCCC2=O)C=C(C(=O)OC)C1c1ccccc1C(F)(F)F
COC(=O)C1=CN(CCCN2CCCC2=O)C=C(C(=O)OC)C1c1ccccc1C(F)(F)F
dimethyl1-[3-(2-oxopyrrolidin-1-yl)propyl]-4-[2-(trifluoromethyl)phenyl]-4H-pyridine-3,5-dicarboxylate