Task: Answer the MCQ question.
Question: Which compound has a -8.447% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(Cn1nc(-c2ccccc2Cl)ccc1=O)Nc1ccc(Br)cc1
b.) O=[N+]([O-])c1ccc(-n2cccc2/C=N/Nc2nc(N3CCCCC3)nc(N3CCCCC3)n2)cc1
c.) CC1(C)COC(Nc2cccc(Cl)c2)=N1
d.) Cc1ccc(CN2CCN(/N=C/c3cc(Br)cc(Br)c3O)CC2)cc1
e.) CCOC(=O)C(C)Sc1nc2c(c(-c3cccs3)c1C#N)CCC2
Answer: e. CCOC(=O)C(C)Sc1nc2c(c(-c3cccs3)c1C#N)CCC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C(C)Sc1nc2c(c(-c3cccs3)c1C#N)CCC2
CCOC(=O)C(C)Sc1nc2c(c(-c3cccs3)c1C#N)CCC2
ethyl 2-[(3-cyano-4-thiophen-2-yl-6,7-dihydro-5H-cyclopenta[b]pyridin-2-yl)sulfanyl]propanoate