Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 6.275% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1ccc(C)c(S(=O)(=O)Nc2ccc(C(N)=O)cc2)c1
(b) Cc1nc(N)ncc1C(=O)Nc1ccccc1
(c) Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccccc3)nn2)s1
(d) COC(=O)C1=C(C)Nc2nc(-c3ccccc3)nn2C1c1ccc(C)o1
(e) Cc1ccc(C)c(S(=O)(=O)Nc2ccccc2C(=O)N2c3ccccc3CC2C)c1
Answer: c. Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccccc3)nn2)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccccc3)nn2)s1
Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccccc3)nn2)s1
2-[6-(2,4-dimethyl-1,3-thiazol-5-yl)pyridazin-3-yl]sulfanyl-N-phenylacetamide