Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -12.228% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CN(Cc1ccccc1)C(=O)c1nn2cccnc2c1Cl
[b] COc1ccc(C(O)c2ncc(C(F)(F)F)cc2Cl)cc1
[c] C=CCNC(=O)CN1CCN(C(c2ccccc2)c2ccccc2)CC1.O=C(O)C(=O)O
[d] COCCn1c(-c2ccccc2Cl)nc2c(c(=O)c3ccccc3n2C)c1=O
[e] CCc1ccc(NS(=O)(=O)c2cccs2)cc1
Answer: d. COCCn1c(-c2ccccc2Cl)nc2c(c(=O)c3ccccc3n2C)c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCn1c(-c2ccccc2Cl)nc2c(c(=O)c3ccccc3n2C)c1=O
COCCn1c(-c2ccccc2Cl)nc2c(c(=O)c3ccccc3n2C)c1=O
2-(2-chlorophenyl)-3-(2-methoxyethyl)-10-methylpyrimido[4,5-b]quinoline-4,5-dione