Task: Answer the multiple-choice question.
Question: Which drug exhibits a -4.517% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1cccc(C(C)C)c1NC(=O)COC(=O)Cc1ccsc1
b. COc1ccc(C/C(C)=N/NC(=S)Nc2ccc(Cl)cc2)cc1
c. COc1cc2c(cc1OC)C(C)N(C(=O)c1sc(-c3cnccn3)nc1C)CC2
d. C=CCN(C(=O)CNS(=O)(=O)c1ccccc1)C(C(=O)NCCOC)c1cccnc1
e. Cc1cc(C(=O)Nc2ccc(Cl)c(S(=O)(=O)N3CCOCC3)c2)c2ccccc2n1
Answer: c. COc1cc2c(cc1OC)C(C)N(C(=O)c1sc(-c3cnccn3)nc1C)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(C)N(C(=O)c1sc(-c3cnccn3)nc1C)CC2
COc1cc2c(cc1OC)C(C)N(C(=O)c1sc(-c3cnccn3)nc1C)CC2
(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methyl-2-pyrazin-2-yl-1,3-thiazol-5-yl)methanone