Problem statement: Answer the MCQ question.
Question: Which compound has a -19.811% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1cc(C(C#N)N2CCC(c3ccccc3)=N2)ccc1O
b) O=C(CN1CCN(c2ccccc2O)CC1)Nc1cc(S(=O)(=O)N2CCCC2)ccc1Cl
c) Cc1ccc(S(=O)(=O)N2CCN(C(=O)CC3CCCC3)CC2)cc1
d) Cn1ncc2c(Nc3ccccc3Cl)nc(Nc3ccccc3Cl)nc21
e) COC(=O)c1ccc(Cl)cc1N(Cc1c(F)cccc1Cl)S(C)(=O)=O
Answer: e. COC(=O)c1ccc(Cl)cc1N(Cc1c(F)cccc1Cl)S(C)(=O)=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(Cl)cc1N(Cc1c(F)cccc1Cl)S(C)(=O)=O
COC(=O)c1ccc(Cl)cc1N(Cc1c(F)cccc1Cl)S(C)(=O)=O
methyl 4-chloro-2-[(2-chloro-6-fluorophenyl)methyl-methylsulfonylamino]benzoate