Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -3.190% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cl.O=C(c1cccs1)c1coc2ccc(O)c(CN(CCO)CCO)c12
b) CC(C)CNC(=O)c1c(F)c(F)c(F)c(F)c1F
c) COc1cccc(NC(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)c1
d) N#CCCN(Cc1cccnc1)C(=O)Nc1ccccc1
e) O=C(Cn1cc(/C=N/NC(=O)c2ccccc2Br)c2ccccc21)Nc1ccc(F)cc1
Answer: c. COc1cccc(NC(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(NC(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)c1
COc1cccc(NC(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)c1
N-(3-methoxyphenyl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carboxamide