Task: Answer the multiple choice question.
Question: Which drug has a -3.986% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a.) COc1ccc2[nH]cc(CCN=C(N)N)c2c1.I
b.) COCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(OC(F)(F)F)cc1)C2
c.) COc1ccc(S(=O)(=O)Nc2nc3ccccc3s2)cc1
Answer: b. COCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(OC(F)(F)F)cc1)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(OC(F)(F)F)cc1)C2
COCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(OC(F)(F)F)cc1)C2
methyl (1R,5S)-8-(2-methoxyethylcarbamoyl)-3-[4-(trifluoromethoxy)phenyl]-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate