Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -13.145% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1cccc(C(=O)/C=C/Nc2ccc(S(=O)(=O)Nc3cc(OC)nc(OC)n3)cc2)c1
b: CCn1c(SCC(=O)c2ccc(Cl)s2)nnc1-c1cccs1
c: O=C(NC1CCC(CC2CCC(NC(=O)C(Cl)Cl)CC2)CC1)C(Cl)Cl
d: Cc1cccc(COCC(Cc2ccccc2)N2CCN(C(=O)c3ccc(C(F)(F)F)cc3)CCC2=O)c1
e: CC1CC(C)CN(S(=O)(=O)N2CCC(C(=O)NCc3ccco3)CC2)C1
Answer: d. Cc1cccc(COCC(Cc2ccccc2)N2CCN(C(=O)c3ccc(C(F)(F)F)cc3)CCC2=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cccc(COCC(Cc2ccccc2)N2CCN(C(=O)c3ccc(C(F)(F)F)cc3)CCC2=O)c1
Cc1cccc(COCC(Cc2ccccc2)N2CCN(C(=O)c3ccc(C(F)(F)F)cc3)CCC2=O)c1
4-[1-[(3-methylphenyl)methoxy]-3-phenylpropan-2-yl]-1-[4-(trifluoromethyl)benzoyl]-1,4-diazepan-5-one