Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -12.514% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(N/N=C/c1cc([N+](=O)[O-])ccc1O)C1CC1
b.) COc1ccc(Br)cc1CNC(=O)Cc1c(C(=O)O)[nH]c2ccc(Cl)cc12
c.) C=CCNC(=S)Nc1ccc(N2CCOCC2)c(S(=O)(=O)Nc2ccccc2Cl)c1
d.) CCc1ccc(NC(=O)CSc2nncn2-c2cccnc2)cc1
e.) NC(=O)C1CCN(C(=O)/C(=C/c2ccco2)NC(=O)c2ccccc2)CC1
Answer: c. C=CCNC(=S)Nc1ccc(N2CCOCC2)c(S(=O)(=O)Nc2ccccc2Cl)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C=CCNC(=S)Nc1ccc(N2CCOCC2)c(S(=O)(=O)Nc2ccccc2Cl)c1
C=CCNC(=S)Nc1ccc(N2CCOCC2)c(S(=O)(=O)Nc2ccccc2Cl)c1
1-[3-[(2-chlorophenyl)sulfamoyl]-4-morpholin-4-ylphenyl]-3-prop-2-enylthiourea