Problem statement: Answer the multiple choice question.
Query: Which compound exhibits a -13.424% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1ccc(NC(=O)C2=NNC(=O)CC2)cc1F
b) O=C(c1ccc(NS(=O)(=O)c2cccs2)cc1)N1CCOCC1
c) Cc1ccc(Oc2ncccc2NC(=O)CC(CC(=O)O)c2ccccc2)c2c1CCC2
d) COC(=O)c1c(C)[nH]c(O)c1C=Nc1ccc(C#N)cc1
e) C/C=C/C=C\C(=O)Nc1cccc(C2=NOC3(C2)C[C@H](C(N)=O)N(C(=O)/C=C/C)C3)c1
Answer: d. COC(=O)c1c(C)[nH]c(O)c1C=Nc1ccc(C#N)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1c(C)[nH]c(O)c1C=Nc1ccc(C#N)cc1
COC(=O)c1c(C)[nH]c(O)c1C=Nc1ccc(C#N)cc1
methyl 4-[(4-cyanophenyl)iminomethyl]-5-hydroxy-2-methyl-1H-pyrrole-3-carboxylate