Problem statement: Answer the multiple-choice question.
Query: Which drug has a -2.491% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cc1cccc(N2CC(C(=O)Nc3ccc(S(=O)(=O)NCC4CCCO4)cc3)CC2=O)c1C
[b] CC(=O)c1cc(C(=O)Nc2ccc(C(=O)O)cc2)oc1C
[c] COC(=O)c1cccc(Nc2nc(-c3cccnc3)nc3ccccc23)c1
[d] CC(C)(C)NS(=O)(=O)c1ccc(CCC(=O)N2CCCC2)cc1
[e] CCCc1[nH]nc2c1C(C(C)C)C(C#N)=C(N)O2
Answer: c. COC(=O)c1cccc(Nc2nc(-c3cccnc3)nc3ccccc23)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cccc(Nc2nc(-c3cccnc3)nc3ccccc23)c1
COC(=O)c1cccc(Nc2nc(-c3cccnc3)nc3ccccc23)c1
methyl 3-[(2-pyridin-3-ylquinazolin-4-yl)amino]benzoate