Problem statement: Answer the MCQ question.
Question: Which compound exhibits a -5.428% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a CN(CC(=O)Nc1ccccc1F)CC(=O)Nc1ccc(F)c(F)c1F
b O=C(CNC(=O)c1ccco1)Nc1cccc(Cl)c1
c O=C(CN1C(=O)NC2(CCCC2)C1=O)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1
d O=C(Cn1cnc([N+](=O)[O-])n1)N/N=C/c1ccc(O)cc1O
Answer: c. O=C(CN1C(=O)NC2(CCCC2)C1=O)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CN1C(=O)NC2(CCCC2)C1=O)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1
O=C(CN1C(=O)NC2(CCCC2)C1=O)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1
3-[2-oxo-2-[4-[3-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]ethyl]-1,3-diazaspiro[4.4]nonane-2,4-dione