Problem statement: Answer the multiple-choice question.
Query: Which drug has a -16.977% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1ccc(Nc2nc(C(=O)NCCCN3CCOCC3)cs2)cc1
[b] O=C(COc1ccc2ccccc2c1Br)N1CCCC1
[c] CC1=C[C@@H](C)[C@@H](c2ccccc2)OC1=O
[d] Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3nn(C(C)C)c(=O)c4ccccc34)CC2)cc1C
[e] CCOc1ccc(NC(=O)CN2CCN(c3ccccc3C)CC2)cc1S(=O)(=O)N1CCCC1
Answer: d. Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3nn(C(C)C)c(=O)c4ccccc34)CC2)cc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3nn(C(C)C)c(=O)c4ccccc34)CC2)cc1C
Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3nn(C(C)C)c(=O)c4ccccc34)CC2)cc1C
4-[4-(3,4-dimethylphenyl)sulfonylpiperazine-1-carbonyl]-2-propan-2-ylphthalazin-1-one