Problem statement: Answer the multiple-choice question.
Query: Which compound has a -9.480% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCOC(=O)C(C)CC(C)C(=O)N1CCOCCN(C(=O)C(C)CC(C)C(=O)OCC)CCOCC1
b) COc1ccc(OC)c(-c2c(=O)n(OCc3ccccc3Br)c3ccccc3[n+]2[O-])c1
c) Cc1cccc2cc(C#N)c(NCCNS(=O)(=O)c3ccc4c(c3)OCCO4)nc12
d) O=C(C1=C[C@H](C2CC2)C[C@H](OCCCCO)O1)N1CCN(Cc2ccc3c(c2)OCO3)CC1
e) O=C(CSc1nc(-c2ccc(F)cc2)cs1)N1CCc2ccccc21
Answer: a. CCOC(=O)C(C)CC(C)C(=O)N1CCOCCN(C(=O)C(C)CC(C)C(=O)OCC)CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C(C)CC(C)C(=O)N1CCOCCN(C(=O)C(C)CC(C)C(=O)OCC)CCOCC1
CCOC(=O)C(C)CC(C)C(=O)N1CCOCCN(C(=O)C(C)CC(C)C(=O)OCC)CCOCC1
ethyl 5-[10-(5-ethoxy-2,4-dimethyl-5-oxopentanoyl)-1,7-dioxa-4,10-diazacyclododec-4-yl]-2,4-dimethyl-5-oxopentanoate