Problem statement: Answer the multiple-choice question.
Query: Which drug has a -53.612% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CCOC(=O)c1ccc(NC(=O)C2CC(=O)Nc3nc4ccccc4n32)cc1
b.) Cc1cccc(OCC(=O)Nc2ccc3c(c2)nc(CCN2CCN(c4ccccn4)CC2)n3C)c1
c.) O=C1C2CSCN2C(=O)CN1CCCN1CCN(C(c2ccccc2)c2ccccc2)CC1
d.) CCc1c(C(=O)N/N=C/c2ccco2)nnn1-c1nonc1N
e.) CC(Sc1ncnc2c1cnn2-c1ccccc1)C(=O)NCC1CCCO1
Answer: c. O=C1C2CSCN2C(=O)CN1CCCN1CCN(C(c2ccccc2)c2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1C2CSCN2C(=O)CN1CCCN1CCN(C(c2ccccc2)c2ccccc2)CC1
O=C1C2CSCN2C(=O)CN1CCCN1CCN(C(c2ccccc2)c2ccccc2)CC1
7-[3-(4-benzhydrylpiperazin-1-yl)propyl]-1,3,6,8a-tetrahydro-[1,3]thiazolo[3,4-a]pyrazine-5,8-dione