Problem statement: Answer the MCQ question.
Query: Which drug has a -9.891% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Oc1c(C(c2cccs2)N2CCN(c3ccccc3)CC2)ccc2cccnc12
b COc1cc(/C=N/NC(=O)c2c(-c3ccccc3)noc2C)ccc1O
c COc1cccc(/C=C/C(=O)OCC(=O)N2c3ccccc3NC(=O)C2(C)C)c1
d Cc1sc(N)c(C(=O)c2ccccc2Cl)c1C
e CCCS(=O)(=O)N1CCC(C(=O)NCc2ccc(F)cc2)CC1
Answer: e. CCCS(=O)(=O)N1CCC(C(=O)NCc2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCS(=O)(=O)N1CCC(C(=O)NCc2ccc(F)cc2)CC1
CCCS(=O)(=O)N1CCC(C(=O)NCc2ccc(F)cc2)CC1
N-[(4-fluorophenyl)methyl]-1-propylsulfonylpiperidine-4-carboxamide