Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -11.855% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. Cc1ccc(S(=O)(=O)NCCNC(=O)C2CCCNC2=O)cc1
b. COc1ccc(-c2nnc(SCc3ccc(C(=O)O)cc3)n2C)cc1OC
c. O=C([O-])c1cc(-c2ccccc2)cc(-c2ccccc2)[n+]1Cc1ccccc1
d. COc1ccc(N2CCN(C(=O)CCNS(=O)(=O)c3cc(Br)cnc3N)CC2)cc1
Answer: d. COc1ccc(N2CCN(C(=O)CCNS(=O)(=O)c3cc(Br)cnc3N)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(C(=O)CCNS(=O)(=O)c3cc(Br)cnc3N)CC2)cc1
COc1ccc(N2CCN(C(=O)CCNS(=O)(=O)c3cc(Br)cnc3N)CC2)cc1
2-amino-5-bromo-N-[3-[4-(4-methoxyphenyl)piperazin-1-yl]-3-oxopropyl]pyridine-3-sulfonamide