Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -10.713% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: COc1ccc(S(=O)(=O)NCc2csc(C)n2)cc1OC
b: Cc1sc(NC(=O)c2cc(-c3ccc(Cl)cc3)nc3ccccc23)c(C(N)=O)c1C
c: O=C(N/C(=C/c1cccs1)c1nc2ccccc2[nH]1)c1ccccc1
d: O=c1[nH]c(CN2CCN(c3ccc(O)cc3)CC2)nc2scc(-c3ccc(Cl)cc3)c12
Answer: d. O=c1[nH]c(CN2CCN(c3ccc(O)cc3)CC2)nc2scc(-c3ccc(Cl)cc3)c12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=c1[nH]c(CN2CCN(c3ccc(O)cc3)CC2)nc2scc(-c3ccc(Cl)cc3)c12
O=c1[nH]c(CN2CCN(c3ccc(O)cc3)CC2)nc2scc(-c3ccc(Cl)cc3)c12
5-(4-chlorophenyl)-2-[[4-(4-hydroxyphenyl)piperazin-1-yl]methyl]-3H-thieno[2,3-d]pyrimidin-4-one