Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -15.003% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1cccc(CN2CCNC(=O)C2CC(=O)NCCN2CCCCC2=O)c1
b: CC(=O)c1c(C)[nH]c(C(=O)Nc2cc(S(=O)(=O)N(C)C)ccc2C)c1C
c: CCc1ccccc1NC(=O)C1c2ccccc2Oc2ccccc21
d: COCCNC(=O)COc1cccc2c1OC(C)(C)C2
e: COc1ccc(C2(c3ccc(O)cc3O)CC(c3ccccc3Cl)NC(=S)N2)cc1
Answer: e. COc1ccc(C2(c3ccc(O)cc3O)CC(c3ccccc3Cl)NC(=S)N2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2(c3ccc(O)cc3O)CC(c3ccccc3Cl)NC(=S)N2)cc1
COc1ccc(C2(c3ccc(O)cc3O)CC(c3ccccc3Cl)NC(=S)N2)cc1
6-(2-chlorophenyl)-4-(2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)-1,3-diazinane-2-thione