Problem statement: Answer the multiple choice question.
Question: Which compound exhibits a -14.384% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. CC(C)c1ccc(CC(NC(=O)c2ccccc2)C(=O)NCC(=O)O)cc1
b. O=C(CSc1nnc(Cc2ccccc2)o1)NCc1ccc2c(c1)OCO2
c. Cc1ccc(S(=O)(=O)N2CC(=O)N3CCCOC3C2)cc1
d. C[C@@H](NC(=O)c1nc[nH]c1C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1)c1ccccc1
Answer: d. C[C@@H](NC(=O)c1nc[nH]c1C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1)c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C[C@@H](NC(=O)c1nc[nH]c1C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1)c1ccccc1
C[C@@H](NC(=O)c1nc[nH]c1C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1)c1ccccc1
tert-butyl 4-[[4-[[(1R)-1-phenylethyl]carbamoyl]-1H-imidazole-5-carbonyl]amino]piperidine-1-carboxylate