Task: Answer the multiple choice question.
Question: Which drug has a -14.878% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. N#Cc1cccc(CN2CCC(=O)N([C@H](CO)Cc3ccccc3)CC2)c1
b. COc1ccc(C2CC(=O)C3=C(C2)Nc2ccccc2N(C(=O)CCC(=O)O)C3c2ccc(F)cc2)cc1
c. COc1ccccc1CCC(=O)Nc1ccc(C)cc1Cl
d. O=C(c1ccc(NC2=NC3CS(=O)(=O)CC3S2)cc1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1
e. COc1ccc(S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)N2CC[C@@]3(O)CCCC[C@H]3C2)cc1
Answer: e. COc1ccc(S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)N2CC[C@@]3(O)CCCC[C@H]3C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)N2CC[C@@]3(O)CCCC[C@H]3C2)cc1
COc1ccc(S(=O)(=O)N[C@@H](Cc2ccccc2)C(=O)N2CC[C@@]3(O)CCCC[C@H]3C2)cc1
N-[(2S)-1-[(4aS,8aS)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-1-oxo-3-phenylpropan-2-yl]-4-methoxybenzenesulfonamide