Task: Answer the MCQ question.
Question: Which compound has a -10.270% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COC(=O)c1sccc1S(=O)(=O)Nc1ccc(S(N)(=O)=O)cc1
[b] Cc1ccc(S(=O)(=O)N2CC(O)CC2C(=O)OCc2nc3sc(C)c(C)c3c(=O)[nH]2)cc1
[c] O=C(Nc1ccnn1C1CCN(C2CCCC2)CC1)c1ccccc1Cl
[d] O=C(Nc1ccc(NC(=O)c2ccccc2Cl)nc1)c1ccco1
[e] COc1ccccc1-c1sc2cc3c(cc2c1C#Cc1ccccn1)OCO3
Answer: a. COC(=O)c1sccc1S(=O)(=O)Nc1ccc(S(N)(=O)=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1sccc1S(=O)(=O)Nc1ccc(S(N)(=O)=O)cc1
COC(=O)c1sccc1S(=O)(=O)Nc1ccc(S(N)(=O)=O)cc1
methyl 3-[(4-sulfamoylphenyl)sulfamoyl]thiophene-2-carboxylate