Task: Answer the multiple choice question.
Query: Which compound exhibits a -31.329% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCCC(=O)C1=C(O)C(C(=O)OC)C(C)(C)CC1=Nc1ccc(C)cc1
b. Cc1cccc2cc(C#N)c(SCC(=O)NCC3CCCO3)nc12
c. O=[N+]([O-])c1cccc(OCC(O)CN2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)c1
d. CC(C)OC(=O)CSc1nnc(-c2cnccn2)n1C
e. COc1ccc(Cc2[nH]n3c(=O)cc(C(C)C)nc3c2-c2ccccc2)cc1
Answer: c. O=[N+]([O-])c1cccc(OCC(O)CN2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=[N+]([O-])c1cccc(OCC(O)CN2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)c1
O=[N+]([O-])c1cccc(OCC(O)CN2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)c1
1-[4-(2,5-dichlorophenyl)sulfonylpiperazin-1-yl]-3-(3-nitrophenoxy)propan-2-ol