Problem statement: Answer the multiple-choice question.
Question: Which drug has a -1.892% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a CCN(CC)c1ccc(N2C(=NC(=O)C3CCCO3)SC3CS(=O)(=O)CC32)cc1
b Cn1nc(C(=O)NNC(=O)CCOc2ccc(C(C)(C)C)cc2)c2ccccc2c1=O
c O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4cc(Cl)ccc4n3)nc3ccsc3c2=O)CC1
d CN(C(=O)c1ccc(Oc2ccc([N+](=O)[O-])cc2)cc1)C1CCCCC1
e Cc1cc(NC(=O)C(=O)c2cn(C)c3ccccc23)no1
Answer: c. O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4cc(Cl)ccc4n3)nc3ccsc3c2=O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4cc(Cl)ccc4n3)nc3ccsc3c2=O)CC1
O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4cc(Cl)ccc4n3)nc3ccsc3c2=O)CC1
2-[(7-chloro-4-oxopyrido[1,2-a]pyrimidin-2-yl)methylsulfanyl]-3-[(4-carboxycyclohexyl)methyl]thieno[3,2-d]pyrimidin-4-one