Task: Answer the multiple-choice question.
Query: Which compound exhibits a 6.422% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1cccc(N2C(=O)CC(N3CCN(S(=O)(=O)c4ccccc4)CC3)C2=O)c1
b) COC(=O)C(CO)NC(=O)C1CCCN1C(=O)CNC(=O)OCc1ccccc1
c) COc1cccc(-c2cc(C(=O)NCc3ccco3)c3ccccc3n2)c1
d) CCCCC(CC)C(=O)Nc1cc(C(=O)NCc2ccc(C)cc2)ccc1N1CCC2(CC1)CC(c1cccc(Br)c1)=NO2
e) COc1ccccc1C(=O)COC(=O)C1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1
Answer: a. COc1cccc(N2C(=O)CC(N3CCN(S(=O)(=O)c4ccccc4)CC3)C2=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(N2C(=O)CC(N3CCN(S(=O)(=O)c4ccccc4)CC3)C2=O)c1
COc1cccc(N2C(=O)CC(N3CCN(S(=O)(=O)c4ccccc4)CC3)C2=O)c1
3-[4-(benzenesulfonyl)piperazin-1-yl]-1-(3-methoxyphenyl)pyrrolidine-2,5-dione