Problem statement: Answer the multiple-choice question.
Question: Which drug has a -17.731% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] Cc1ccc(C(=O)Nc2cc(=O)n(C)c(=O)n2C)cc1C
[b] Cc1ccc(-n2nnnc2SCc2nc3sc(C)c(C)c3c(=O)[nH]2)cc1
[c] O=C(N[C@H]1CC1c1ccccc1)c1ccc([N+](=O)[O-])cc1
[d] Cc1cc(=O)n(-c2ccc(C(=O)O)cc2)[nH]1
[e] CC1CC(C)CN(S(=O)(=O)c2ccc(C(=O)OCC(=O)NCCN3C(=O)CSC3=O)cc2)C1
Answer: e. CC1CC(C)CN(S(=O)(=O)c2ccc(C(=O)OCC(=O)NCCN3C(=O)CSC3=O)cc2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1CC(C)CN(S(=O)(=O)c2ccc(C(=O)OCC(=O)NCCN3C(=O)CSC3=O)cc2)C1
CC1CC(C)CN(S(=O)(=O)c2ccc(C(=O)OCC(=O)NCCN3C(=O)CSC3=O)cc2)C1
[2-[2-(2,4-dioxo-1,3-thiazolidin-3-yl)ethylamino]-2-oxoethyl] 4-(3,5-dimethylpiperidin-1-yl)sulfonylbenzoate