Problem statement: Answer the multiple choice question.
Query: What is the hERG inhibition at a concentration of 1uM of a compound with the SMILES Cc1c(C(=O)N2CCC3(CC2)OCCO3)sc2ncnc(N3CCN(c4ccccn4)CC3)c12?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] 3.027
[b] -8.296
[c] 19.190
[d] 8.769
[e] 11.466
Answer: b. -8.296\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-[5-methyl-4-(4-pyridin-2-ylpiperazin-1-yl)thieno[2,3-d]pyrimidin-6-yl]methanone