Task: Answer the multiple-choice question.
Question: Which drug has a -8.296\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) CCn1ccc(C(=O)NC2=NCCS2)n1
(b) Cc1c(C(=O)N2CCC3(CC2)OCCO3)sc2ncnc(N3CCN(c4ccccn4)CC3)c12
(c) CN(C)c1ccc(Nc2nc(N)c([N+](=O)[O-])c(N3CCOCC3)n2)cc1
(d) O=C(Nc1ccc(OC(F)F)cc1)Nc1cccc(C(F)(F)F)c1
Answer: b. Cc1c(C(=O)N2CCC3(CC2)OCCO3)sc2ncnc(N3CCN(c4ccccn4)CC3)c12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-[5-methyl-4-(4-pyridin-2-ylpiperazin-1-yl)thieno[2,3-d]pyrimidin-6-yl]methanone