Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -33.334\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCOC(=O)C1=C(C)OC(N)=C(C(=O)OCC)C12C(=O)Nc1ccc(Br)cc12
(b) CN(C)c1ccc(/C=N\NC(=S)SCN2C(=O)C3CCC(C)(C2=O)C3(C)C)cc1
(c) COc1ccc(C(=O)/C=C(/C)N(C)C)cc1
(d) O=C(c1cccn2c(=O)c3ccccc3nc12)N1CCN(c2ccccn2)CC1
(e) O=C(O)c1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1
Answer: d. O=C(c1cccn2c(=O)c3ccccc3nc12)N1CCN(c2ccccn2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
6-(1-pyridin-2-ylpiperazine-4-carbonyl)pyrido[2,1-b]quinazolin-11-one