Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -1.376\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CC(=O)Nc1ccc(SCC(=O)N(C)C2CCS(=O)(=O)C2)cc1
b: COc1cccc(-c2nc(-c3ccc(NC(=O)c4ccncc4)cc3)no2)c1
c: CCc1cccc(NC(=O)CN(c2ccc(C)cc2)S(=O)(=O)c2c(C)noc2C)c1
d: CCO[C@H]1OC(C(=O)N2CCOCC2)=C[C@@H](c2coc3ccccc3c2=O)[C@@H]1CCCO
e: COc1ccc(-n2c(=O)cc(N3CCN(Cc4ccccc4)CC3)[nH]c2=O)cc1
Answer: b. COc1cccc(-c2nc(-c3ccc(NC(=O)c4ccncc4)cc3)no2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(-c2nc(-c3ccc(NC(=O)c4ccncc4)cc3)no2)c1
COc1cccc(-c2nc(-c3ccc(NC(=O)c4ccncc4)cc3)no2)c1
N-[4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]pyridine-4-carboxamide