Task: Answer the multiple-choice question.
Query: Which drug has a 8.198\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C(NCC(c1cccs1)N1CCOCC1)C1CCN(S(=O)(=O)c2c(Cl)cccc2Cl)CC1
(b) Nc1nnc(SCc2cccc(C(F)(F)F)c2)s1
(c) COc1cc(/C=C/C(=O)c2ccc3c(c2)OCCO3)cc(Br)c1OCC(=O)N(C)C
(d) COC(=O)C1=C(N)Oc2cc(C)n(C)c(=O)c2C1c1ccc(Cl)cc1
(e) O=c1oc2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2s1
Answer: a. O=C(NCC(c1cccs1)N1CCOCC1)C1CCN(S(=O)(=O)c2c(Cl)cccc2Cl)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCC(c1cccs1)N1CCOCC1)C1CCN(S(=O)(=O)c2c(Cl)cccc2Cl)CC1
O=C(NCC(c1cccs1)N1CCOCC1)C1CCN(S(=O)(=O)c2c(Cl)cccc2Cl)CC1
1-(2,6-dichlorophenyl)sulfonyl-N-(2-morpholin-4-yl-2-thiophen-2-ylethyl)piperidine-4-carboxamide