Problem statement: Answer the MCQ question.
Question: Which drug has a -1.091\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. O=C(CC(=O)N/N=C/c1c(Cl)cccc1Cl)NCc1cccnc1
b. Cc1ccc(NC(=O)Nc2ccc(Cl)cc2)c(Br)c1
c. CC(=O)Nc1ccc(S(=O)(=O)NCCC(=O)N2CCCCC2)cc1
d. CCn1nnnc1SCC(=O)Nc1cc(C)on1
e. COc1cc([C@@H]2C[C@H]3CN(c4ccccc4)C(=O)[C@]34CCCN24)cc(OC)c1OC
Answer: e. COc1cc([C@@H]2C[C@H]3CN(c4ccccc4)C(=O)[C@]34CCCN24)cc(OC)c1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc([C@@H]2C[C@H]3CN(c4ccccc4)C(=O)[C@]34CCCN24)cc(OC)c1OC
COc1cc([C@@H]2C[C@H]3CN(c4ccccc4)C(=O)[C@]34CCCN24)cc(OC)c1OC
(1S,5S,7S)-3-phenyl-7-(3,4,5-trimethoxyphenyl)-3,8-diazatricyclo[6.3.0.01,5]undecan-2-one