Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 19.356\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a. CCS(=O)(=O)c1ccc(O)c(NC(=O)Nc2ccccc2OC)c1
b. O=C(COc1ccccc1N1C(=O)c2ccccc2C1=O)c1ccc(Cl)cc1
c. CCOC(=O)c1nc(C)sc1-c1ccnn1S(=O)(=O)c1cccc(Cl)c1
Answer: c. CCOC(=O)c1nc(C)sc1-c1ccnn1S(=O)(=O)c1cccc(Cl)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1nc(C)sc1-c1ccnn1S(=O)(=O)c1cccc(Cl)c1
CCOC(=O)c1nc(C)sc1-c1ccnn1S(=O)(=O)c1cccc(Cl)c1
ethyl 5-[2-(3-chlorophenyl)sulfonylpyrazol-3-yl]-2-methyl-1,3-thiazole-4-carboxylate