Problem statement: Answer the MCQ question.
Question: Which drug has a -2.934\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: O=C(OCc1nc2ccsc2c(=O)[nH]1)c1ccccc1
b: COc1ccc(CNC(=O)C[C@H]2C(=O)N(C3CCCCC3)C[C@@H]2Cc2ccccc2)cc1
c: COc1cccc(C(=O)Nc2cccc(NC(=O)c3cccs3)c2)c1
d: COc1ccc(CS(=O)(=O)CC(C)(O)c2ccccc2)cc1
e: CCc1nc2sc3c(c2c(=O)n1N)CC(C)(C)OC3
Answer: b. COc1ccc(CNC(=O)C[C@H]2C(=O)N(C3CCCCC3)C[C@@H]2Cc2ccccc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C[C@H]2C(=O)N(C3CCCCC3)C[C@@H]2Cc2ccccc2)cc1
COc1ccc(CNC(=O)C[C@H]2C(=O)N(C3CCCCC3)C[C@@H]2Cc2ccccc2)cc1
2-[(3R,4R)-4-benzyl-1-cyclohexyl-2-oxopyrrolidin-3-yl]-N-[(4-methoxyphenyl)methyl]acetamide