Problem statement: Answer the multiple-choice question.
Query: Which compound has a -10.898\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(S(=O)(=O)NCc2cccnc2)cc1
(b) CCN(CC)C(=O)CCc1nnc(CCc2c[nH]c3ccccc23)o1
(c) COc1ccccc1NC(=O)C(C)Sc1nc(-c2ccccc2)cn1N
(d) CCN1C(=O)/C(=C\C(=O)c2cccs2)c2cc(Br)ccc21
(e) COc1cccc(N(C(=O)C2COc3ccccc3O2)C(C(=O)NC2CCCCC2)c2ccc(O)cc2)c1
Answer: c. COc1ccccc1NC(=O)C(C)Sc1nc(-c2ccccc2)cn1N
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1NC(=O)C(C)Sc1nc(-c2ccccc2)cn1N
COc1ccccc1NC(=O)C(C)Sc1nc(-c2ccccc2)cn1N
2-(1-amino-4-phenylimidazol-2-yl)sulfanyl-N-(2-methoxyphenyl)propanamide