Task: Answer the multiple-choice question.
Query: Which drug exhibits a -15.957\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a) COc1ccc2oc(C(=O)Nc3ccc(N4CCOCC4)cc3)c(C)c2c1
b) COc1ccc(NC(=O)c2ccc(COc3ccccc3OC)o2)cc1OC
c) COc1ccc(-c2c(Cl)nc(N[C@@H](C)c3ccccc3)c(=O)n2-c2ccccc2)cc1OC
d) CCOc1ccc(S(=O)(=O)N2CCCC(C(=O)NCc3ccccn3)C2)cc1Cl
Answer: c. COc1ccc(-c2c(Cl)nc(N[C@@H](C)c3ccccc3)c(=O)n2-c2ccccc2)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2c(Cl)nc(N[C@@H](C)c3ccccc3)c(=O)n2-c2ccccc2)cc1OC
COc1ccc(-c2c(Cl)nc(N[C@@H](C)c3ccccc3)c(=O)n2-c2ccccc2)cc1OC
5-chloro-6-(3,4-dimethoxyphenyl)-1-phenyl-3-[[(1S)-1-phenylethyl]amino]pyrazin-2-one