Problem statement: Answer the multiple choice question.
Question: Which compound has a 8.427\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccc(CC2(CO)CCN(S(=O)(=O)c3c(C)nn(C)c3Cl)CC2)cc1
b: O=C(C1CCN(c2nc(-c3ccccc3)nc3c2CCC3)CC1)N1CCC(O)CC1
c: COc1ccc(C(=O)C2CCCN(C(=O)c3ccnn3C)C2)c(C)c1
d: O=C(Cn1ccc2ccccc2c1=O)NCCC(=O)N1CCN(c2cccc(Cl)c2)CC1
e: Cl.OCCNCc1cc(Br)ccc1OCc1ccc(Cl)cc1
Answer: d. O=C(Cn1ccc2ccccc2c1=O)NCCC(=O)N1CCN(c2cccc(Cl)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Cn1ccc2ccccc2c1=O)NCCC(=O)N1CCN(c2cccc(Cl)c2)CC1
O=C(Cn1ccc2ccccc2c1=O)NCCC(=O)N1CCN(c2cccc(Cl)c2)CC1
N-[3-[4-(3-chlorophenyl)piperazin-1-yl]-3-oxopropyl]-2-(1-oxoisoquinolin-2-yl)acetamide