Problem statement: Answer the multiple choice question.
Question: Which compound has a -36.988\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Cc1ccccc1[C@@H](NC(=O)OC(C)(C)C)C(=O)OC(C)(C)C
b.) Cc1ccccc1N1C(=S)NC2c3ccccc3OC1(C)C2C(=O)N(C)C
c.) COc1cc(OC)c(OC)cc1CN1CCN(c2ccc(F)cc2)CC1
d.) CN(Cc1ccc(F)cc1)Cc1nc(-c2cnccn2)no1
e.) O=c1nc2n(c3ncccc13)CCCCC2
Answer: c. COc1cc(OC)c(OC)cc1CN1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(OC)c(OC)cc1CN1CCN(c2ccc(F)cc2)CC1
COc1cc(OC)c(OC)cc1CN1CCN(c2ccc(F)cc2)CC1
1-(4-fluorophenyl)-4-[(2,4,5-trimethoxyphenyl)methyl]piperazine