Problem statement: Answer the multiple-choice question.
Query: Which drug has a -5.881\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(NC(=O)CCN2CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)cc1
b) Cc1nn(Cc2ccc(Cl)cc2)c(C)c1NC(=O)CCCn1nc(C)c([N+](=O)[O-])c1C
c) Cc1c(Cc2ccccc2)c(=O)oc2cc(O)cc(O)c12
d) Cc1ccc(S(=O)(=O)Nc2ccc3cn[nH]c3c2)cc1
e) C/C(CC(=O)Nc1ccc(Cl)cc1Cl)=N\NC(=O)C(=O)NCCO
Answer: a. COc1ccc(NC(=O)CCN2CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)CCN2CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)cc1
COc1ccc(NC(=O)CCN2CCN(S(=O)(=O)c3ccc(OC)cc3)CC2)cc1
N-(4-methoxyphenyl)-3-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]propanamide