Problem statement: Answer the multiple choice question.
Question: Which compound has a 4.588\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) S=c1[nH]c(-c2ccc(Br)cc2)cn1CCc1ccccc1
b.) O=C(c1ccc(F)cc1)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccccc3Br)CC2)CC1
c.) Cc1cc(C)c(NC(=O)Nc2ccc3c(c2)OCO3)c(C)c1
d.) COc1ccc(C(=O)Nc2ccnn2C2CCN(Cc3ccc4nonc4c3)CC2)cc1
e.) CCCNC(=O)COC(=O)c1ccc(OCC(=O)Nc2ccccc2OC)c(OC)c1
Answer: b. O=C(c1ccc(F)cc1)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccccc3Br)CC2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccc(F)cc1)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccccc3Br)CC2)CC1
O=C(c1ccc(F)cc1)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccccc3Br)CC2)CC1
[4-(2-bromophenyl)sulfonylpiperazin-1-yl]-[1-(4-fluorobenzoyl)piperidin-4-yl]methanone