Problem statement: Answer the MCQ question.
Question: Which drug has a -1.047\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1cccc(NC(=O)Nc2nnc(-c3ccccc3SCc3ccccc3)s2)c1
b.) Cc1cc(Br)ccc1SCC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1
c.) CC1CCN(C(=O)CSc2nnc(Cc3cccn3C)n2-c2ccc(F)cc2)CC1
d.) CSc1nnc(NC(=O)CCc2ccccc2)s1
e.) CCN(CC)S(=O)(=O)c1cc(C(=O)OCC(=O)Nc2cccc(Br)c2)ccc1F
Answer: d. CSc1nnc(NC(=O)CCc2ccccc2)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CSc1nnc(NC(=O)CCc2ccccc2)s1
CSc1nnc(NC(=O)CCc2ccccc2)s1
N-(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)-3-phenylpropanamide