Task: Answer the MCQ question.
Query: Which compound has a 7.821\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1cccc(/C=C/C(=O)OCC(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)c1OC
(b) CCOC(=O)C1CCN(C(=O)CN2C(=O)C(C(C)C)Oc3ccccc32)CC1
(c) CCOc1ccc(CC(=O)Nc2c(C(N)=O)oc3ccccc23)cc1OCC
(d) CCOC(=O)C(/C=C(\C#N)C(=O)OCC)=C(/N)N1CCN(c2ccc(OC)cc2)CC1
(e) Cc1n[nH]c(C)c1S(=O)(=O)N1CCCC(C(=O)NCc2cccs2)C1
Answer: d. CCOC(=O)C(/C=C(\C#N)C(=O)OCC)=C(/N)N1CCN(c2ccc(OC)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C(/C=C(\C#N)C(=O)OCC)=C(/N)N1CCN(c2ccc(OC)cc2)CC1
CCOC(=O)C(/C=C(\C#N)C(=O)OCC)=C(/N)N1CCN(c2ccc(OC)cc2)CC1
diethyl (E,4Z)-4-[amino-[4-(4-methoxyphenyl)piperazin-1-yl]methylidene]-2-cyanopent-2-enedioate