Problem statement: Answer the multiple-choice question.
Query: Which compound has a 3.841\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1ccc(Cl)cc1NC(=O)CN1C(=O)NC2(CCCC2)C1=O
[b] COc1ccc([C@H]2CC(=O)C=C(c3ccc(C)cc3)C2)cc1OC
[c] CN1CCN(CCCNC(=O)c2nnc(Cc3c(F)cccc3Cl)o2)CC1
[d] COc1ccc(Nc2nc(N)c([N+](=O)[O-])c(N3CCN(C)CC3)n2)cc1
[e] CCOC(=O)COc1c(Br)cc(/C=C2\SC(=O)N(CC(=O)N3CCCC3)C2=O)cc1OC
Answer: b. COc1ccc([C@H]2CC(=O)C=C(c3ccc(C)cc3)C2)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@H]2CC(=O)C=C(c3ccc(C)cc3)C2)cc1OC
COc1ccc([C@H]2CC(=O)C=C(c3ccc(C)cc3)C2)cc1OC
(5R)-5-(3,4-dimethoxyphenyl)-3-(4-methylphenyl)cyclohex-2-en-1-one