Problem statement: Answer the multiple choice question.
Question: Which compound has a 12.533\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Cc1cc(/C(N)=N/OC(=O)Nc2cccc(C(F)(F)F)c2)no1
b.) S=C(Nc1ccc2c(c1)OCCO2)Nc1ccccc1Cl
c.) COc1cccc(N2C(=O)CC(N3CCN(CCN=CC4=C(O)CC(C)(C)CC4=O)CC3)C2=O)c1
d.) CCN(CC(=O)Nc1ccc2c(c1)OCCO2)Cc1cc(=O)oc2cc(C)c(C)cc12
e.) Cc1c(OCC(=O)NCc2cccnc2)ccc2c3c(c(=O)oc12)CCCC3
Answer: c. COc1cccc(N2C(=O)CC(N3CCN(CCN=CC4=C(O)CC(C)(C)CC4=O)CC3)C2=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(N2C(=O)CC(N3CCN(CCN=CC4=C(O)CC(C)(C)CC4=O)CC3)C2=O)c1
COc1cccc(N2C(=O)CC(N3CCN(CCN=CC4=C(O)CC(C)(C)CC4=O)CC3)C2=O)c1
3-[4-[2-[(2-hydroxy-4,4-dimethyl-6-oxocyclohexen-1-yl)methylideneamino]ethyl]piperazin-1-yl]-1-(3-methoxyphenyl)pyrrolidine-2,5-dione