Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 5.220\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: C=CCNc1nnc(SC2CC(=O)N(c3ccc(OC)cc3)C2=O)s1
b: O=C(COC(=O)c1cc([N+](=O)[O-])ccc1N1CCOCC1)NCc1ccc(F)cc1
c: COCc1ccc([C@@H]2C[C@H]3CN(Cc4cccnc4)C(=O)[C@]34CCCN24)o1
d: O=C(Nc1ccc(F)cc1)N1CCCC(c2nc3c(nnn3Cc3ccccc3Cl)c(=O)[nH]2)C1
e: COC(=O)c1[nH]c2c(c1C)C(=O)CC(c1cccc(OC)c1)C2
Answer: c. COCc1ccc([C@@H]2C[C@H]3CN(Cc4cccnc4)C(=O)[C@]34CCCN24)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCc1ccc([C@@H]2C[C@H]3CN(Cc4cccnc4)C(=O)[C@]34CCCN24)o1
COCc1ccc([C@@H]2C[C@H]3CN(Cc4cccnc4)C(=O)[C@]34CCCN24)o1
(1S,5S,7S)-7-[5-(methoxymethyl)furan-2-yl]-3-(pyridin-3-ylmethyl)-3,8-diazatricyclo[6.3.0.01,5]undecan-2-one