Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 1.050\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C(Cc1ccccc1)Nn1c(-c2ccccc2)nc2ccccc2c1=O
(b) O=C(c1ccccc1)c1cccc(C(=O)c2ccccc2)c1
(c) COc1ccccc1N1CCN(Cc2ccc(F)cc2)CC1
(d) COc1ccccc1N1CCN(C(=O)C(=O)c2cn(CC(=O)N3CCCCCC3)c3ccccc23)CC1
(e) c1cn(CC2(Cn3ccnc3)COC2)cn1
Answer: d. COc1ccccc1N1CCN(C(=O)C(=O)c2cn(CC(=O)N3CCCCCC3)c3ccccc23)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CCN(C(=O)C(=O)c2cn(CC(=O)N3CCCCCC3)c3ccccc23)CC1
COc1ccccc1N1CCN(C(=O)C(=O)c2cn(CC(=O)N3CCCCCC3)c3ccccc23)CC1
1-[1-[2-(azepan-1-yl)-2-oxoethyl]indol-3-yl]-2-[4-(2-methoxyphenyl)piperazin-1-yl]ethane-1,2-dione