Problem statement: Answer the multiple-choice question.
Query: Which compound has a -12.590\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1cccc(CNCCNC(=O)c2nonc2N)c1.Cl
b: COc1ccc(C2CC(c3ccc(Cl)cc3Cl)Nc3nc(N)nn32)cc1OC
c: Cc1cc(CN(C)C(=O)c2cc(COc3ccc4ncccc4c3)on2)on1
d: CN(CCO)C(=O)c1c(NC(=O)c2ccccc2)sc2c1CCCC2
e: COc1ccc(F)cc1S(=O)(=O)NCC(c1ccc2c(c1)OCO2)N1CCN(C)CC1
Answer: e. COc1ccc(F)cc1S(=O)(=O)NCC(c1ccc2c(c1)OCO2)N1CCN(C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(F)cc1S(=O)(=O)NCC(c1ccc2c(c1)OCO2)N1CCN(C)CC1
COc1ccc(F)cc1S(=O)(=O)NCC(c1ccc2c(c1)OCO2)N1CCN(C)CC1
N-[2-(1,3-benzodioxol-5-yl)-2-(4-methylpiperazin-1-yl)ethyl]-5-fluoro-2-methoxybenzenesulfonamide