Problem statement: Answer the MCQ question.
Question: Which drug has a -46.281\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1cc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)cc(OC)c1OC.O=C(O)C(=O)O
b. N#Cc1cc([N+](=O)[O-])ccc1NCCc1ccccn1
c. CSCCC(NC(=O)c1ccccc1)C(=O)N1CC(C)OC(C)C1
d. CCCCNC(=O)N1CCN(c2ccnc3cc(Cl)ccc23)CC1
e. O=C(/C=C/c1cccc([N+](=O)[O-])c1)N1CCN(Cc2ccc3c(c2)OCO3)CC1
Answer: d. CCCCNC(=O)N1CCN(c2ccnc3cc(Cl)ccc23)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCNC(=O)N1CCN(c2ccnc3cc(Cl)ccc23)CC1
CCCCNC(=O)N1CCN(c2ccnc3cc(Cl)ccc23)CC1
N-butyl-4-(7-chloroquinolin-4-yl)piperazine-1-carboxamide