Problem statement: Answer the multiple-choice question.
Question: Which compound has a -2.493\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1cccc(/C=N/N2CCN(c3ccccc3OC)CC2)c1
b CCc1nnc(NC(=O)C(NS(=O)(=O)c2ccc3c(c2)OCCO3)C(C)C)s1
c CC1(C)Cc2cccc(OCC(=O)N3CCN(c4ccc(F)cc4)CC3)c2O1
d COc1cccc(OC)c1C(=O)NC(=S)N1C[C@H]2C[C@H](C1)c1cccc(=O)n1C2
e CCC(=O)NCCSc1c[nH]c2ccccc12
Answer: b. CCc1nnc(NC(=O)C(NS(=O)(=O)c2ccc3c(c2)OCCO3)C(C)C)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1nnc(NC(=O)C(NS(=O)(=O)c2ccc3c(c2)OCCO3)C(C)C)s1
CCc1nnc(NC(=O)C(NS(=O)(=O)c2ccc3c(c2)OCCO3)C(C)C)s1
2-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonylamino)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-3-methylbutanamide