Task: Answer the MCQ question.
Query: Which drug exhibits a 12.772\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: O=c1c(F)cn(C2CCCO2)c(=O)n1Cc1c(F)cccc1Cl
b: C#CCOCCOCCOCCNc1nc(N2CCN(C(=O)Cn3cc(CCO)nn3)CC2)nc(N2CCN(C(=O)[C@H]([C@@H](C)O)n3cc(CCCC[NH3+])nn3)CC2)n1.[Cl-]
c: CC(CCc1ccccc1)NC(=O)CN1CCN(c2ccc(O)cc2)CC1
d: COc1ccc(S(=O)(=O)N2CCOC23CCN(S(=O)(=O)c2ccc(C)cc2)CC3)cc1
Answer: d. COc1ccc(S(=O)(=O)N2CCOC23CCN(S(=O)(=O)c2ccc(C)cc2)CC3)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)N2CCOC23CCN(S(=O)(=O)c2ccc(C)cc2)CC3)cc1
COc1ccc(S(=O)(=O)N2CCOC23CCN(S(=O)(=O)c2ccc(C)cc2)CC3)cc1
4-(4-methoxyphenyl)sulfonyl-8-(4-methylphenyl)sulfonyl-1-oxa-4,8-diazaspiro[4.5]decane