Problem statement: Answer the multiple-choice question.
Question: Which compound has a 0.359\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a O=C(Nc1ccc(Cl)cc1C(F)(F)F)C(Sc1nnc(-c2cccs2)o1)c1ccccc1
b CN(CCCNC(=O)CCc1cn(C)c2ccccc12)C1CCCCC1
c Cc1cc(Br)ccc1NC(=O)CNC(=O)CSc1ncccn1
d CCCCC(=O)Nc1c(O)c2ccccc2[nH]c1=O
e Cn1c(SCCN2CCCC2)nnc1C1CCN(S(=O)(=O)c2ccc(F)cc2)CC1
Answer: a. O=C(Nc1ccc(Cl)cc1C(F)(F)F)C(Sc1nnc(-c2cccs2)o1)c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1ccc(Cl)cc1C(F)(F)F)C(Sc1nnc(-c2cccs2)o1)c1ccccc1
O=C(Nc1ccc(Cl)cc1C(F)(F)F)C(Sc1nnc(-c2cccs2)o1)c1ccccc1
N-[4-chloro-2-(trifluoromethyl)phenyl]-2-phenyl-2-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide