Task: Answer the multiple choice question.
Question: Which drug exhibits a -11.217\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1cc(CN2CCNC(=O)C2CC(=O)NC2CCCC2)cc(OC)c1
b) Cc1cc2c(cc1C)-c1nnc(-c3ccc4ccccc4n3)n1C(C)(C)C2
c) N#Cc1ccc(NCC(=O)Nc2ccc(S(=O)(=O)N3CCCCC3)cc2)cc1
d) COc1ccc2c(c1)c1nc3ccccc3nc1n2Cc1ccc(OC(C)C)c(OC)c1
e) CC(=O)N1CN2CN(C(C)=O)CC(C(=O)c3ccc([N+](=O)[O-])cc3)(C2)C1
Answer: a. COc1cc(CN2CCNC(=O)C2CC(=O)NC2CCCC2)cc(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(CN2CCNC(=O)C2CC(=O)NC2CCCC2)cc(OC)c1
COc1cc(CN2CCNC(=O)C2CC(=O)NC2CCCC2)cc(OC)c1
N-cyclopentyl-2-[1-[(3,5-dimethoxyphenyl)methyl]-3-oxopiperazin-2-yl]acetamide