Problem statement: Answer the multiple-choice question.
Query: Which compound has a 30.031\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a O=C(/C=C/c1cccs1)c1cc(F)ccc1OC(=O)N1CCOCC1
b O=C(CSc1nc(-c2ccccc2)cc(C(F)(F)F)n1)NCc1cccs1
c COc1ccccc1NC(=O)Cn1cnc2sc(C(=O)Nc3cc(OC)c(OC)c(OC)c3)c(C)c2c1=O
d COc1ccc(-c2csc(/C(C#N)=C(\O)CSc3nccn3C)n2)cc1OC
e O=S(=O)(Nc1cccc(S(=O)(=O)N2CCOCC2)c1)c1cccs1
Answer: c. COc1ccccc1NC(=O)Cn1cnc2sc(C(=O)Nc3cc(OC)c(OC)c(OC)c3)c(C)c2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1NC(=O)Cn1cnc2sc(C(=O)Nc3cc(OC)c(OC)c(OC)c3)c(C)c2c1=O
COc1ccccc1NC(=O)Cn1cnc2sc(C(=O)Nc3cc(OC)c(OC)c(OC)c3)c(C)c2c1=O
3-[2-(2-methoxyanilino)-2-oxoethyl]-5-methyl-4-oxo-N-(3,4,5-trimethoxyphenyl)thieno[2,3-d]pyrimidine-6-carboxamide