Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -58.258\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(C(=O)C2CCCN(Cc3cccc(C)n3)C2)c(OC)c1
b. COc1ccc(/C=N/NC(=O)CSC2CN(C(c3ccccc3)c3ccccc3)C2)cc1
c. CN1CCN(CC#CCOc2ccc(Cl)cc2)CC1.O=C(O)C(=O)O
d. Cc1ccc(-n2cccn2)c(CN2CCCC(C(=O)c3sccc3C)C2)c1
e. O=C1NC(=O)c2cc(NC(=O)C3COc4ccccc4O3)ccc21
Answer: a. COc1ccc(C(=O)C2CCCN(Cc3cccc(C)n3)C2)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)C2CCCN(Cc3cccc(C)n3)C2)c(OC)c1
COc1ccc(C(=O)C2CCCN(Cc3cccc(C)n3)C2)c(OC)c1
(2,4-dimethoxyphenyl)-[1-[(6-methylpyridin-2-yl)methyl]piperidin-3-yl]methanone