Problem statement: Answer the MCQ question.
Query: Which compound has a 5.531\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(Nc1ccc2c(c1)OCO2)N1CCN(c2ncccn2)CC1
b.) Cc1nn(S(=O)(=O)c2ccc(F)cc2)c(C)c1S(=O)(=O)N1CCOCC1
c.) CCCC(=O)c1ccc(N2CCN(C(=O)c3cccs3)CC2)c(F)c1
d.) N#Cc1ccc(C2=NC(C(F)(F)F)(C(F)(F)F)c3c(n(Cc4ccco4)c(=O)[nH]c3=O)N2)cc1
e.) Cc1ccc(/C=C2/SC(=S)N(CCC(=O)NCCCN3CCOCC3)C2=O)cc1
Answer: d. N#Cc1ccc(C2=NC(C(F)(F)F)(C(F)(F)F)c3c(n(Cc4ccco4)c(=O)[nH]c3=O)N2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#Cc1ccc(C2=NC(C(F)(F)F)(C(F)(F)F)c3c(n(Cc4ccco4)c(=O)[nH]c3=O)N2)cc1
N#Cc1ccc(C2=NC(C(F)(F)F)(C(F)(F)F)c3c(n(Cc4ccco4)c(=O)[nH]c3=O)N2)cc1
4-[1-(furan-2-ylmethyl)-2,4-dioxo-5,5-bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidin-7-yl]benzonitrile