Task: Answer the MCQ question.
Query: What is the hERG inhibition at 1uM of a drug with the SMILES COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCc2cc(OC)c(OC)cc2C1?
Constraint: You must return none, one or more options from a, b, c, or d without using any additional words.
Options:
a) -0.413
b) 11.948
c) 15.016
d) 13.510
Answer: c. 15.016\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCc2cc(OC)c(OC)cc2C1
COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCc2cc(OC)c(OC)cc2C1
methyl (1R,5S)-8-(6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbonyl)-3-(3-fluoro-4-phenylphenyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate