Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -59.821\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O=C(CSc1nc(-c2ccco2)cc(C(F)(F)F)n1)Nc1ccccc1C(F)(F)F
[b] CCN(CC)c1ccc(/C=C(\C#N)C(=O)NCc2ccccc2)cc1
[c] O=C(COc1ncnc2c(Cl)cc(Cl)cc12)Nc1cc([N+](=O)[O-])ccc1Cl
[d] Cn1cc([C@@H]2C[C@H]3CN(Cc4cccc(Cl)c4)C(=O)[C@]34CCCN24)c(-c2ccccc2)n1
[e] CCOC(=O)C1(CCCc2ccccc2)CCN(Cc2cn(CC)nc2C)CC1
Answer: e. CCOC(=O)C1(CCCc2ccccc2)CCN(Cc2cn(CC)nc2C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1(CCCc2ccccc2)CCN(Cc2cn(CC)nc2C)CC1
CCOC(=O)C1(CCCc2ccccc2)CCN(Cc2cn(CC)nc2C)CC1
ethyl 1-[(1-ethyl-3-methylpyrazol-4-yl)methyl]-4-(3-phenylpropyl)piperidine-4-carboxylate