Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 5.645\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. Cc1ccc(NC(=O)COC(=O)c2ccc(=O)n(Cc3ccccc3)n2)cc1F
b. COc1cccc(CNC(=O)C2CCC(CNc3c(N4CCC(C)CC4)c(=O)c3=O)CC2)c1
c. CCOc1cc(C2C(C(=O)OC(C)C)=C(C)NC3=C2C(=O)CCC3)cc([N+](=O)[O-])c1O
d. COc1ccc(CCN(C)C(=O)C2CCN(Cc3cccc(OC)c3OC)CC2)cc1OC.O=C(O)C(=O)O
Answer: b. COc1cccc(CNC(=O)C2CCC(CNc3c(N4CCC(C)CC4)c(=O)c3=O)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)C2CCC(CNc3c(N4CCC(C)CC4)c(=O)c3=O)CC2)c1
COc1cccc(CNC(=O)C2CCC(CNc3c(N4CCC(C)CC4)c(=O)c3=O)CC2)c1
N-[(3-methoxyphenyl)methyl]-4-[[[2-(4-methylpiperidin-1-yl)-3,4-dioxocyclobuten-1-yl]amino]methyl]cyclohexane-1-carboxamide