Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -7.443\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc([C@H]2CC(=O)C=C(c3cccc(Cl)c3)C2)cc1OC
(b) CCCCNC(=O)NC1(C(F)(F)F)Oc2ccccc2O1
(c) COCCC(=O)N1CCCC(C(=O)c2ccc(C(F)(F)F)cc2)C1
(d) CCn1cnc2c(oc3ccccc32)c1=O
(e) Cc1ccc(Oc2c(CO)c(-c3ccccc3)nn2C)cc1
Answer: a. COc1ccc([C@H]2CC(=O)C=C(c3cccc(Cl)c3)C2)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@H]2CC(=O)C=C(c3cccc(Cl)c3)C2)cc1OC
COc1ccc([C@H]2CC(=O)C=C(c3cccc(Cl)c3)C2)cc1OC
(5R)-3-(3-chlorophenyl)-5-(3,4-dimethoxyphenyl)cyclohex-2-en-1-one