Problem statement: Answer the MCQ question.
Question: Which drug has a -38.422\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a or b without using any additional words.
Options:
a: CCOC(=O)C1CCCN(C(=S)Nc2cccc(Cl)c2)C1
b: COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1ccc(S(=O)(=O)N(C)C)cc1)CC2
Answer: b. COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1ccc(S(=O)(=O)N(C)C)cc1)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1ccc(S(=O)(=O)N(C)C)cc1)CC2
COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1ccc(S(=O)(=O)N(C)C)cc1)CC2
4-(6,7-dimethoxy-1-thiophen-2-yl-3,4-dihydro-1H-isoquinoline-2-carbonyl)-N,N-dimethylbenzenesulfonamide