Task: Answer the multiple-choice question.
Question: Which compound has a 8.751\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCOC(=O)C1(Cc2cccc(OC)c2)CCCN(Cc2nccn2CC)C1
b. CCCOC(=O)c1ccc(Oc2cn[nH]c2-c2ccc(OC)cc2O)cc1
c. CNC[C@H](Cc1ccccc1)NC[C@@H](Cc1cccc2ccccc12)NCCc1ccc(C)cc1
d. COc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)cc1
e. O=C(C1CCCO1)N1CCN(Cc2nc3ccccc3c(=O)[nH]2)CC1
Answer: d. COc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)cc1
COc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)cc1
N-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]-2-(4-methoxyphenoxy)acetamide