Task: Answer the multiple choice question.
Question: Which compound has a 4.354\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] O=c1c2c(ncn2C2CCCC2)n(Cc2ccccc2)c(=O)n1CCOc1ccc(Br)cc1
[b] Cc1nnc(SC(C)C(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)n1N
[c] COC(=O)COc1nc(C)c2c(c1C#N)CC(C)(C)OC2
[d] CCOC(=O)c1sc(=S)n(-c2ccc(OC)cc2)c1C
Answer: c. COC(=O)COc1nc(C)c2c(c1C#N)CC(C)(C)OC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)COc1nc(C)c2c(c1C#N)CC(C)(C)OC2
COC(=O)COc1nc(C)c2c(c1C#N)CC(C)(C)OC2
methyl 2-[(5-cyano-3,3,8-trimethyl-1,4-dihydropyrano[3,4-c]pyridin-6-yl)oxy]acetate