Problem statement: Answer the multiple choice question.
Question: Which drug has a -5.621\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(CCN2CN(S(=O)(=O)c3ccccc3)c3nc4ccccc4nc32)cc1
(b) CC(CC(=O)NC1CCSC1=O)c1ccccc1
(c) COc1ccc(OC2C(=O)N(CCc3ccc(OC)c(OC)c3)C2c2ccc3c(c2)OCO3)cc1
(d) Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3ccc(-n4cncn4)c([N+](=O)[O-])c3)CC2)cc1
(e) CCOC(=O)c1ccc(S(=O)(=O)N2CCN(CC(O)COc3ccc(C#N)cc3)CC2)cc1.O=C(O)C(=O)O
Answer: a. COc1ccc(CCN2CN(S(=O)(=O)c3ccccc3)c3nc4ccccc4nc32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CCN2CN(S(=O)(=O)c3ccccc3)c3nc4ccccc4nc32)cc1
COc1ccc(CCN2CN(S(=O)(=O)c3ccccc3)c3nc4ccccc4nc32)cc1
1-(benzenesulfonyl)-3-[2-(4-methoxyphenyl)ethyl]-2H-imidazo[4,5-b]quinoxaline