Problem statement: Answer the multiple-choice question.
Question: Which compound has a 7.228\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CN1CC(=O)NC1=NC(=O)C12CC3CC(CC(C3)C1)C2
b: CCCc1nnc(SCC(=O)N2CCCCC2)n1CC1CCCO1
c: COc1ccc(CNC(=S)Nc2ccc(F)c(Cl)c2)cc1OC
d: O=C1N(Cc2cccc(Cl)c2)C[C@@H]2C[C@@H](c3ccccn3)N3CCC[C@@]123
e: CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C
Answer: d. O=C1N(Cc2cccc(Cl)c2)C[C@@H]2C[C@@H](c3ccccn3)N3CCC[C@@]123
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1N(Cc2cccc(Cl)c2)C[C@@H]2C[C@@H](c3ccccn3)N3CCC[C@@]123
O=C1N(Cc2cccc(Cl)c2)C[C@@H]2C[C@@H](c3ccccn3)N3CCC[C@@]123
(1S,5S,7S)-3-[(3-chlorophenyl)methyl]-7-pyridin-2-yl-3,8-diazatricyclo[6.3.0.01,5]undecan-2-one