Problem statement: Answer the multiple-choice question.
Question: Which drug has a -11.169\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cc1c(Cl)cccc1NC(=S)N=Nc1c(O)n(CN2CCOCC2)c2ccccc12
b COc1ccc2cc(C#N)c(SCC(=O)N3CC(=O)Nc4ccccc43)nc2c1
c O=C(CCSCCc1ccccn1)Nc1ccccn1
d COc1cc(OC)cc(C(=O)N2CCN(c3ncccn3)CC2)c1
e CNC(=O)NC(=O)C(C)N1CCN(C/C=C/c2ccccc2)CC1
Answer: d. COc1cc(OC)cc(C(=O)N2CCN(c3ncccn3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(OC)cc(C(=O)N2CCN(c3ncccn3)CC2)c1
COc1cc(OC)cc(C(=O)N2CCN(c3ncccn3)CC2)c1
(3,5-dimethoxyphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone