Problem statement: Answer the multiple-choice question.
Question: Which drug has a 0.436\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CC(=O)c1ccc(S(=O)(=O)N2CCN(CC(=O)Nc3ccccc3C(=O)NC3CC3)CC2)cc1
b. Cc1c(-c2ccc(F)cc2)nc(N)c(C#N)c1-c1ccco1
c. C=CCc1c(C)nc(C)nc1N/N=C/c1ccccc1
d. COC(=O)[C@H](C)NC(=O)N1CCC(Cc2ccccc2)CC1
e. N#Cc1c(N2CCSCC2)nsc1-c1ccccc1Cl
Answer: d. COC(=O)[C@H](C)NC(=O)N1CCC(Cc2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)[C@H](C)NC(=O)N1CCC(Cc2ccccc2)CC1
COC(=O)[C@H](C)NC(=O)N1CCC(Cc2ccccc2)CC1
methyl (2S)-2-[(4-benzylpiperidine-1-carbonyl)amino]propanoate