Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -20.137\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(COC(=O)c1cc2ccccc2oc1=O)Nc1ccc(F)cc1F
b. CSc1ncccc1C(=O)Nc1cccc(S(=O)(=O)N2CCCCC2)c1
c. CCCN=Cc1ccc(O)cc1
d. Cc1ccc(S(=O)(=O)CCN2CCC(O)(c3ccccc3)CC2)cc1
e. Cc1ccccc1CNC(=O)C1CCC(=O)N(CC2CCCCC2)C1
Answer: b. CSc1ncccc1C(=O)Nc1cccc(S(=O)(=O)N2CCCCC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CSc1ncccc1C(=O)Nc1cccc(S(=O)(=O)N2CCCCC2)c1
CSc1ncccc1C(=O)Nc1cccc(S(=O)(=O)N2CCCCC2)c1
2-methylsulfanyl-N-(3-piperidin-1-ylsulfonylphenyl)pyridine-3-carboxamide