Problem statement: Answer the MCQ question.
Question: Which drug has a -10.098\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1cccc(NC(=O)Cn2nc(C(F)(F)F)cc2C2CC2)c1
b) COc1ccc(-c2nc3c(c(=O)[nH]c(=O)n3Cc3ccccc3)n2Cc2ccccc2)cc1
c) O=[N+]([O-])c1cc(-c2nc(-c3ccncc3)no2)cc([N+](=O)[O-])c1
d) Cc1ccc2nc(-c3ccccc3O)c(Nc3ccc4c(c3)OCCO4)n2c1
e) Cc1ccc(CNC(=O)C2CCCN(c3nc4ccsc4c(=O)s3)C2)cc1
Answer: a. Cc1cccc(NC(=O)Cn2nc(C(F)(F)F)cc2C2CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cccc(NC(=O)Cn2nc(C(F)(F)F)cc2C2CC2)c1
Cc1cccc(NC(=O)Cn2nc(C(F)(F)F)cc2C2CC2)c1
2-[5-cyclopropyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(3-methylphenyl)acetamide