Problem statement: Answer the MCQ question.
Query: Which drug has a -56.661\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(c1cccs1)N1CCN(c2ncccn2)CC1
b.) COc1ccc(CC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1
c.) CCn1cc(C(=O)NCCC2=CCCCC2)c(=O)c2cc(S(=O)(=O)N(C)C)ccc21
d.) CC(C)C(NC(=O)c1cccnc1)C(=O)O
e.) CCN1CCN(c2cc(C)c3cc(NC(=S)N(C)Cc4ccccc4)ccc3n2)CC1
Answer: e. CCN1CCN(c2cc(C)c3cc(NC(=S)N(C)Cc4ccccc4)ccc3n2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1CCN(c2cc(C)c3cc(NC(=S)N(C)Cc4ccccc4)ccc3n2)CC1
CCN1CCN(c2cc(C)c3cc(NC(=S)N(C)Cc4ccccc4)ccc3n2)CC1
1-benzyl-3-[2-(4-ethylpiperazin-1-yl)-4-methylquinolin-6-yl]-1-methylthiourea