Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 18.573\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(CCNC(=O)c2ccc(CN3CCC(Cc4ccccc4)CC3)cc2)cc1OC
b. CC1(C(=O)NNC(=O)c2ccc(=O)oc2)CC1Br
c. COc1cc(OC)cc(-c2nnc(NC(=O)Cc3ccc(F)cc3)o2)c1
d. C/C(=N/NC(=O)c1ccc(C(C)(C)C)cc1)c1cccnc1
e. c1ccc2c(CSc3nnc(-c4ccncc4)o3)cccc2c1
Answer: c. COc1cc(OC)cc(-c2nnc(NC(=O)Cc3ccc(F)cc3)o2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(OC)cc(-c2nnc(NC(=O)Cc3ccc(F)cc3)o2)c1
COc1cc(OC)cc(-c2nnc(NC(=O)Cc3ccc(F)cc3)o2)c1
N-[5-(3,5-dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]-2-(4-fluorophenyl)acetamide