Problem statement: Answer the multiple choice question.
Question: Which compound has a 5.454\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CCCc1ccc(-c2c(C)sc(N)c2C#N)cc1
b.) Cc1cccc(N2CCN(c3nc4ccccc4n4cnnc34)CC2)c1C
c.) COC(=O)c1sc(N)c(C(=O)OC)c1COC(=O)CNS(=O)(=O)c1ccc(C)cc1
d.) COc1ccc(NC(=O)CN2CCN(c3ccc(C)cc3C)CC2)cc1
e.) COc1cc(C(=O)NCCC(=O)N2CCCCC2)cc(OC)c1OC
Answer: c. COC(=O)c1sc(N)c(C(=O)OC)c1COC(=O)CNS(=O)(=O)c1ccc(C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1sc(N)c(C(=O)OC)c1COC(=O)CNS(=O)(=O)c1ccc(C)cc1
COC(=O)c1sc(N)c(C(=O)OC)c1COC(=O)CNS(=O)(=O)c1ccc(C)cc1
dimethyl 5-amino-3-[[2-[(4-methylphenyl)sulfonylamino]acetyl]oxymethyl]thiophene-2,4-dicarboxylate