Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a -10.870\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a: COc1cccc(CNC(=O)C(=O)N2CCC3(CC2)OCCN3S(=O)(=O)c2ccc(C)cc2)c1
b: CCN(CC(=O)Nc1c(F)cccc1F)C(=O)CSCc1c(C)noc1C
c: CCn1ncc([N+](=O)[O-])c1C(=O)Nc1cc(C)on1
d: NC(=O)c1ccc(NC(=O)COC(=O)CCN=C2NS(=O)(=O)c3ccccc32)cc1
Answer: a. COc1cccc(CNC(=O)C(=O)N2CCC3(CC2)OCCN3S(=O)(=O)c2ccc(C)cc2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)C(=O)N2CCC3(CC2)OCCN3S(=O)(=O)c2ccc(C)cc2)c1
COc1cccc(CNC(=O)C(=O)N2CCC3(CC2)OCCN3S(=O)(=O)c2ccc(C)cc2)c1
N-[(3-methoxyphenyl)methyl]-2-[4-(4-methylphenyl)sulfonyl-1-oxa-4,8-diazaspiro[4.5]decan-8-yl]-2-oxoacetamide