Problem statement: Answer the MCQ question.
Query: Which compound has a 6.427\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc(-c2cc(=O)oc3c(C)c(OC(C)C(=O)NCc4ccccn4)ccc23)cc1
(b) Cc1cc(C)nc(-n2ncc3c2CC(c2ccc(C(C)C)cc2)CC3=O)n1
(c) COC(=O)CSc1nc(NCC(C)C)nc(N2CCOCC2)n1
(d) CCN(CC)C(=O)CSc1nc(-c2ccccc2)ccc1C#N
(e) CCCCn1c(=O)[nH]c(=O)c2c1nc(-c1ccc(OCC)cc1)n2CC
Answer: a. COc1ccc(-c2cc(=O)oc3c(C)c(OC(C)C(=O)NCc4ccccn4)ccc23)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2cc(=O)oc3c(C)c(OC(C)C(=O)NCc4ccccn4)ccc23)cc1
COc1ccc(-c2cc(=O)oc3c(C)c(OC(C)C(=O)NCc4ccccn4)ccc23)cc1
2-[4-(4-methoxyphenyl)-8-methyl-2-oxochromen-7-yl]oxy-N-(pyridin-2-ylmethyl)propanamide