Problem statement: Answer the MCQ question.
Question: Which compound has a 8.398\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc2nc(NC(=O)C3CCCN3S(=O)(=O)c3ccc(C)cc3)sc2c1
b. NC(=O)c1c(NC(=O)CN2C(=O)CCC2=O)sc2c1CCCCC2
c. O=C(c1ccccc1-c1nc(-c2ccc(Cl)cc2)no1)N1CCCC1
d. COc1cc(/C=N/NC(=O)CC23CC4CC(CC(C4)C2)C3)cc(Br)c1OCC(=O)N(C)C
e. COc1cc(NC(=O)C2Cc3ccccc3CN2S(C)(=O)=O)cc(OC)c1
Answer: e. COc1cc(NC(=O)C2Cc3ccccc3CN2S(C)(=O)=O)cc(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(NC(=O)C2Cc3ccccc3CN2S(C)(=O)=O)cc(OC)c1
COc1cc(NC(=O)C2Cc3ccccc3CN2S(C)(=O)=O)cc(OC)c1
N-(3,5-dimethoxyphenyl)-2-methylsulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxamide