Problem statement: Answer the multiple choice question.
Question: Which compound exhibits a -3.492\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1cccc(NC(=O)Nc2c(C)[nH]c(=O)[nH]c2=O)c1C
b) COc1cc(OC)cc(-c2nc3ccccc3c(=O)n2OC(=O)c2ccc(C)c(C)c2)c1
c) CCN(CC(=O)Nc1c(F)cccc1F)C(=O)CCSc1ccc(C)cc1
d) CCOC(=O)CNC(=O)c1c(C)nn(C)c1Cl
e) COc1ccc2c(c1)c(C(C)=O)c(C)n2Cc1ccco1
Answer: b. COc1cc(OC)cc(-c2nc3ccccc3c(=O)n2OC(=O)c2ccc(C)c(C)c2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(OC)cc(-c2nc3ccccc3c(=O)n2OC(=O)c2ccc(C)c(C)c2)c1
COc1cc(OC)cc(-c2nc3ccccc3c(=O)n2OC(=O)c2ccc(C)c(C)c2)c1
[2-(3,5-dimethoxyphenyl)-4-oxoquinazolin-3-yl] 3,4-dimethylbenzoate