Problem statement: Answer the multiple choice question.
Query: Which compound exhibits a -22.754\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCc1nn(CCCC(=O)NC(C)c2ccccc2)c(=O)c2cc3occc3n12
b) O=C(c1cccc(S(=O)(=O)N2CCCC2)c1)N1CCCC(C(F)(F)F)C1
c) CCCC(=O)Nc1ccc(-c2nc3ncccc3o2)cc1
d) O=C(COC(=O)C1CC(=O)N(C2CCCCC2)C1)c1ccc(F)cc1
e) CN=c1scc(-c2cc(OC)ccc2OC)n1/N=C/c1c(C)[nH]c2ccccc12
Answer: d. O=C(COC(=O)C1CC(=O)N(C2CCCCC2)C1)c1ccc(F)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)C1CC(=O)N(C2CCCCC2)C1)c1ccc(F)cc1
O=C(COC(=O)C1CC(=O)N(C2CCCCC2)C1)c1ccc(F)cc1
[2-(4-fluorophenyl)-2-oxoethyl]1-cyclohexyl-5-oxopyrrolidine-3-carboxylate