Problem statement: Answer the multiple choice question.
Question: Which drug has a -3.917\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CCCc1c(C(=O)Nc2ccc(F)cc2F)cnn1-c1ccccc1
b: COc1ccc(CN(C)C(=O)Cn2ccsc2=N)cc1OC.Cl
c: O=C1C=C(c2ccc(F)nc2)C[C@@H](c2ccc3c(c2)OCO3)C1
d: COc1ccc(NC(=O)C(Cc2cc(C)cc(C)c2)C(C)C(=O)O)cc1
e: CCC(c1nnnn1Cc1ccco1)N(Cc1ccccc1OC)Cc1cc2cc(C)ccc2[nH]c1=O
Answer: e. CCC(c1nnnn1Cc1ccco1)N(Cc1ccccc1OC)Cc1cc2cc(C)ccc2[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC(c1nnnn1Cc1ccco1)N(Cc1ccccc1OC)Cc1cc2cc(C)ccc2[nH]c1=O
CCC(c1nnnn1Cc1ccco1)N(Cc1ccccc1OC)Cc1cc2cc(C)ccc2[nH]c1=O
3-[[1-[1-(furan-2-ylmethyl)tetrazol-5-yl]propyl-[(2-methoxyphenyl)methyl]amino]methyl]-6-methyl-1H-quinolin-2-one