Problem statement: Answer the multiple-choice question.
Question: Which drug has a -8.904\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cc1cc(N2CCN(Cc3ccccc3)CC2)n2nc(C)c(-c3ccccc3)c2n1
[b] CCCCNC(=S)N/N=C/c1cccc(OCC)c1O
[c] O=C(O)CSc1ncnc2nc[nH]c12
[d] CCOC(=O)Cn1nc(C)c(NC(=O)COc2ccc(OC)cc2)c1C
[e] CN(C)S(=O)(=O)c1ccc2oc(SCC(=O)NCC(F)(F)F)nc2c1
Answer: e. CN(C)S(=O)(=O)c1ccc2oc(SCC(=O)NCC(F)(F)F)nc2c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(C)S(=O)(=O)c1ccc2oc(SCC(=O)NCC(F)(F)F)nc2c1
CN(C)S(=O)(=O)c1ccc2oc(SCC(=O)NCC(F)(F)F)nc2c1
2-[[5-(dimethylsulfamoyl)-1,3-benzoxazol-2-yl]sulfanyl]-N-(2,2,2-trifluoroethyl)acetamide