Problem statement: Answer the multiple choice question.
Query: Which compound has a -12.364\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: N#CC(c1ccc(F)cc1)c1ccc(C(=O)c2ccccc2)cc1
b: CCOC(=O)N1CCN(C(=O)CN(c2ccc(OCC)cc2)S(C)(=O)=O)CC1
c: O=C(O)c1nc(-c2ccccc2)n(-c2ccccc2)n1
d: CCOC(=O)C1CCCN(C(=O)c2cccc(NC(=O)C(CC)CC)c2)C1
e: Cl.Cn1nnc(C(O)CNCc2ccc(Cl)cc2)n1
Answer: b. CCOC(=O)N1CCN(C(=O)CN(c2ccc(OCC)cc2)S(C)(=O)=O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)CN(c2ccc(OCC)cc2)S(C)(=O)=O)CC1
CCOC(=O)N1CCN(C(=O)CN(c2ccc(OCC)cc2)S(C)(=O)=O)CC1
ethyl 4-[2-(4-ethoxy-N-methylsulfonylanilino)acetyl]piperazine-1-carboxylate