Problem statement: Answer the multiple-choice question.
Question: Which drug has a 7.810\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1ccc(CCNC(=O)CN2CCN(c3ccccc3Cl)CC2)cc1
b: COc1ccccc1CNC(=O)c1ccc(Cl)c(NC2=NC3CS(=O)(=O)CC3S2)c1
c: CCCCNC(=S)N(CCCN(C)C)Cc1cc2cc3c(cc2[nH]c1=O)OCO3
d: FC(F)Oc1ccc(NC(=S)NCCc2ccccn2)cc1
e: c1ccc(Nc2nnc(-c3cccc4ccccc34)o2)cc1
Answer: b. COc1ccccc1CNC(=O)c1ccc(Cl)c(NC2=NC3CS(=O)(=O)CC3S2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1CNC(=O)c1ccc(Cl)c(NC2=NC3CS(=O)(=O)CC3S2)c1
COc1ccccc1CNC(=O)c1ccc(Cl)c(NC2=NC3CS(=O)(=O)CC3S2)c1
4-chloro-3-[(5,5-dioxo-3a,4,6,6a-tetrahydrothieno[3,4-d][1,3]thiazol-2-yl)amino]-N-[(2-methoxyphenyl)methyl]benzamide