Problem statement: Answer the multiple choice question.
Query: Which drug has a -18.450\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1ccc(C(=O)Nc2ccccc2N2CCCC2)s1
b CCn1nc(C)c(C2C(C#N)=C(N)OC3=C2C(=O)CCC3)c1C
c CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)Nc3nnc(C)o3)cc2)CC1
d COc1cc2c(cc1OC)CN(C(=O)/C=C/c1ccc([N+](=O)[O-])cc1)CC2
e Cc1ccc(CNC(=O)CCC(=O)N2CC(C)Sc3ccccc32)cc1
Answer: d. COc1cc2c(cc1OC)CN(C(=O)/C=C/c1ccc([N+](=O)[O-])cc1)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)CN(C(=O)/C=C/c1ccc([N+](=O)[O-])cc1)CC2
COc1cc2c(cc1OC)CN(C(=O)/C=C/c1ccc([N+](=O)[O-])cc1)CC2
(E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(4-nitrophenyl)prop-2-en-1-one