Problem statement: Answer the MCQ question.
Question: Which drug has a 12.850\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a. COc1ccccc1C(=O)NNC(=O)C1CCN(C(=O)OC(C)(C)C)CC1
b. O=C(c1ccc(Cl)cc1Cl)N1CCC(C(=O)N2CCOCC2)CC1
c. COc1ccc(Cn2c(O)c(C=Nc3ccc(OC)cc3)c3ccccc3c2=O)cc1
Answer: c. COc1ccc(Cn2c(O)c(C=Nc3ccc(OC)cc3)c3ccccc3c2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(Cn2c(O)c(C=Nc3ccc(OC)cc3)c3ccccc3c2=O)cc1
COc1ccc(Cn2c(O)c(C=Nc3ccc(OC)cc3)c3ccccc3c2=O)cc1
3-hydroxy-4-[(4-methoxyphenyl)iminomethyl]-2-[(4-methoxyphenyl)methyl]isoquinolin-1-one