Task: Answer the MCQ question.
Query: Which drug has a 9.654\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COC(=O)[C@H](Cc1ccccc1)NC(=O)NC(C)CCc1ccccc1
b.) COc1ccc(NC(=O)CN(C)C(=O)C2CSC3(C)CCC(=O)N23)cc1
c.) Cc1cccc([C@@H]2[C@@H]3C(=O)N(Cc4ccccc4)C(=O)[C@@H]3[C@]3(Cc4ccc(Cl)cc4)C(=O)N(c4cccc(Br)c4)C(=O)N23)c1
d.) COc1ccc2c(c1)c(CCN1C(=O)c3ccccc3C1=O)cn2C(=O)c1ccco1
e.) O=C(NCCOc1ccc(Cl)cc1)c1ccco1
Answer: c. Cc1cccc([C@@H]2[C@@H]3C(=O)N(Cc4ccccc4)C(=O)[C@@H]3[C@]3(Cc4ccc(Cl)cc4)C(=O)N(c4cccc(Br)c4)C(=O)N23)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cccc([C@@H]2[C@@H]3C(=O)N(Cc4ccccc4)C(=O)[C@@H]3[C@]3(Cc4ccc(Cl)cc4)C(=O)N(c4cccc(Br)c4)C(=O)N23)c1
Cc1cccc([C@@H]2[C@@H]3C(=O)N(Cc4ccccc4)C(=O)[C@@H]3[C@]3(Cc4ccc(Cl)cc4)C(=O)N(c4cccc(Br)c4)C(=O)N23)c1
(1S,2R,7S,8R)-10-benzyl-4-(3-bromophenyl)-2-[(4-chlorophenyl)methyl]-7-(3-methylphenyl)-4,6,10-triazatricyclo[6.3.0.02,6]undecane-3,5,9,11-tetrone