Task: Answer the MCQ question.
Question: Which drug has a 10.829\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CCn1ncc(/C=N\NC(=O)c2cc(-c3ccc(C)cc3C)nc3ccccc23)c1C
b: C/C(=N\NC(=O)c1ccn[nH]1)c1cn(C)nc1C
c: COc1ccc(/C=C(\NC(=O)c2ccc(C)cc2)C(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1
d: COc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](C(C)=O)C[C@@H]12
e: COc1cccc(CNC(=O)[C@@H](C)N2C(=O)N3CCc4c([nH]c5ccc(OC)cc45)C3(C)C2=O)c1
Answer: e. COc1cccc(CNC(=O)[C@@H](C)N2C(=O)N3CCc4c([nH]c5ccc(OC)cc45)C3(C)C2=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)[C@@H](C)N2C(=O)N3CCc4c([nH]c5ccc(OC)cc45)C3(C)C2=O)c1
COc1cccc(CNC(=O)[C@@H](C)N2C(=O)N3CCc4c([nH]c5ccc(OC)cc45)C3(C)C2=O)c1
(2R)-2-(12-methoxy-2-methyl-3,5-dioxo-4,6,16-triazatetracyclo[7.7.0.02,6.010,15]hexadeca-1(9),10(15),11,13-tetraen-4-yl)-N-[(3-methoxyphenyl)methyl]propanamide