Problem statement: Answer the multiple-choice question.
Question: Which drug has a -18.069\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O=C(Cn1cnc2ccccc21)Nc1ccc2c(c1)OCCCO2
[b] O=C(CN1C(=O)CNC1=O)Nc1cccc(C(F)(F)F)c1
[c] COc1c(C)cc(C(=O)C2CCCN(Cc3ccc(Oc4ncccn4)cc3)C2)cc1C
[d] O=C1OCCC1Sc1nnc(-c2ccc(O)cc2)o1
[e] CC(NCc1ccccc1Cl)C(=O)Nc1ccc(S(=O)(=O)N2CCCC2)cc1
Answer: c. COc1c(C)cc(C(=O)C2CCCN(Cc3ccc(Oc4ncccn4)cc3)C2)cc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1c(C)cc(C(=O)C2CCCN(Cc3ccc(Oc4ncccn4)cc3)C2)cc1C
COc1c(C)cc(C(=O)C2CCCN(Cc3ccc(Oc4ncccn4)cc3)C2)cc1C
(4-methoxy-3,5-dimethylphenyl)-[1-[(4-pyrimidin-2-yloxyphenyl)methyl]piperidin-3-yl]methanone