Problem statement: Answer the multiple-choice question.
Question: Which compound has a 19.750\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a C=CCn1c(C)cc(C(=O)COC(=O)C2CC(=O)N(CCc3ccc(OC)c(OC)c3)C2)c1C
b COCC1CCCCN1C(=O)c1cc(COc2ccc3ncccc3c2)on1
c CCC(=O)N1CCc2cc(S(=O)(=O)NC(Cc3ccccc3)C(=O)NC3CCCC3)ccc21
d CCc1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)cc1
e COC(=O)c1ccc(NC2(C#N)C(=O)Nc3ccccc32)cc1
Answer: e. COC(=O)c1ccc(NC2(C#N)C(=O)Nc3ccccc32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(NC2(C#N)C(=O)Nc3ccccc32)cc1
COC(=O)c1ccc(NC2(C#N)C(=O)Nc3ccccc32)cc1
methyl4-[(3-cyano-2-oxo-1H-indol-3-yl)amino]benzoate