Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 8.606\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(S(=O)(=O)NCC(=O)NCc2cc(=O)n(C)c(=O)n2C)cc1F
b) O=C(CNC(=O)c1ccc(Br)o1)NNC(=O)c1ccc(Br)cc1
c) O=C(CSc1ccc2nnc(CCNC(=O)c3ccc(F)cc3)n2n1)NCC1CCCO1
d) CC1CCCCN1C(=O)CN1C(=O)NC2(CCCCC2C)C1=O
e) COc1cc(C(=O)N2CCC(n3c(C)nc4cc(F)ccc43)CC2)cc(OC)c1OC
Answer: c. O=C(CSc1ccc2nnc(CCNC(=O)c3ccc(F)cc3)n2n1)NCC1CCCO1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CSc1ccc2nnc(CCNC(=O)c3ccc(F)cc3)n2n1)NCC1CCCO1
O=C(CSc1ccc2nnc(CCNC(=O)c3ccc(F)cc3)n2n1)NCC1CCCO1
4-fluoro-N-[2-[6-[2-oxo-2-(oxolan-2-ylmethylamino)ethyl]sulfanyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]ethyl]benzamide