Problem statement: Answer the MCQ question.
Query: What is the human ether-à-go-go related gene (hERG) inhibition at 1uM of a compound with the SMILES COc1cccc(NC(=O)C2C3C=CC4(O3)C2C(=O)N(CCN2CCCCC2)C4C(=O)NC2CCCCC2C)c1?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) 19.168
b.) 1.860
c.) -2.255
d.) 10.534
e.) 8.674
Answer: a. 19.168\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COc1cccc(NC(=O)C2C3C=CC4(O3)C2C(=O)N(CCN2CCCCC2)C4C(=O)NC2CCCCC2C)c1
COc1cccc(NC(=O)C2C3C=CC4(O3)C2C(=O)N(CCN2CCCCC2)C4C(=O)NC2CCCCC2C)c1
6-N-(3-methoxyphenyl)-2-N-(2-methylcyclohexyl)-4-oxo-3-(2-piperidin-1-ylethyl)-10-oxa-3-azatricyclo[5.2.1.01,5]dec-8-ene-2,6-dicarboxamide