Task: Answer the multiple-choice question.
Question: Which drug has a 12.515\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: CC1CCCCN1C(=O)COC(=O)C1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1
b: COC(=O)/C(=C\Nc1ccc(Cl)c2ccccc12)c1ncc(C(F)(F)F)cc1Cl
c: COC(=O)c1ccc(CN2CCc3ccccc32)cc1
d: COC(=O)C1(C(=O)OC)NOC2C(=O)N(N(C)c3ncc(C(F)(F)F)cc3Cl)C(=O)C21
Answer: b. COC(=O)/C(=C\Nc1ccc(Cl)c2ccccc12)c1ncc(C(F)(F)F)cc1Cl
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)/C(=C\Nc1ccc(Cl)c2ccccc12)c1ncc(C(F)(F)F)cc1Cl
COC(=O)/C(=C\Nc1ccc(Cl)c2ccccc12)c1ncc(C(F)(F)F)cc1Cl
methyl (Z)-3-[(4-chloronaphthalen-1-yl)amino]-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]prop-2-enoate