Task: Answer the multiple choice question.
Query: Which drug has a 16.155\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCN(CC)C(=O)c1nc[nH]c1C(=O)N1CCc2ccccc2C1
b) CN(C)C1(CNC(=O)C2CCN(S(=O)(=O)c3ccccc3C(F)(F)F)CC2)CCCCC1
c) COc1ccccc1CNC(=O)CN1C(=O)COc2ccc(S(=O)(=O)NC3CCCC3)cc21
d) Cc1ccc(CNC(=O)c2ccc(N3CCC4(CC3)CC(c3cccc(Br)c3)=NO4)c(N)c2)cc1
e) CCOC(=O)N1CCN(C(=O)Cc2c(C(=O)O)n(C)c3ccccc23)CC1
Answer: d. Cc1ccc(CNC(=O)c2ccc(N3CCC4(CC3)CC(c3cccc(Br)c3)=NO4)c(N)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(CNC(=O)c2ccc(N3CCC4(CC3)CC(c3cccc(Br)c3)=NO4)c(N)c2)cc1
Cc1ccc(CNC(=O)c2ccc(N3CCC4(CC3)CC(c3cccc(Br)c3)=NO4)c(N)c2)cc1
3-amino-4-[3-(3-bromophenyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl]-N-[(4-methylphenyl)methyl]benzamide