Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a 5.538\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: O=C1CCC(C(=O)N(c2ccccc2)C2(C(=O)NC3CCCCC3)CCCCC2)N1
b: O=C(COC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1)Nc1ccc(F)cc1F
c: O=C(/C=C/NNC(=O)c1ccccc1)c1ccccc1
d: COC(=O)C1(Cc2cc(-c3ccc(Cl)cc3)no2)CCN(C(=O)OC(C)(C)C)CC1
e: Cc1cc(C)n(Cc2ccc(C(=O)N/N=C/c3ccc(-c4ccc([N+](=O)[O-])cc4)o3)o2)n1
Answer: b. O=C(COC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1)Nc1ccc(F)cc1F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1)Nc1ccc(F)cc1F
O=C(COC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1)Nc1ccc(F)cc1F
N-(2,4-difluorophenyl)-2-[oxo-(1-thiophen-2-ylsulfonylpiperidin-4-yl)methoxy]acetamide