Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 16.288\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a: COC(=O)C1=C(c2ccc(OCc3ccccc3)cc2)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(OC)c(OC)c1
b: CCN(CC(=O)NCc1ccc(Cl)cc1)C(=O)CN1C(=O)NC(CC)(c2ccccc2)C1=O
c: O=C(NCc1ccco1)c1noc2c1CCCCC2
d: N#C/C(=C(/O)c1ccc(Cl)cc1)c1nc2ccccc2[nH]1
Answer: a. COC(=O)C1=C(c2ccc(OCc3ccccc3)cc2)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(OC)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(OCc3ccccc3)cc2)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(OC)c(OC)c1
COC(=O)C1=C(c2ccc(OCc3ccccc3)cc2)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(OC)c(OC)c1
methyl (1R,5S)-8-[(3,4-dimethoxyphenyl)methylcarbamoyl]-3-(4-phenylmethoxyphenyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate