Problem statement: Answer the MCQ question.
Question: Which drug has a -32.327\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Cc1ccc(S(=O)(=O)N(C)CCCC(=O)NC(C)(C)CO)cc1
b.) Cn1nc(C(=O)Nc2ccc3c(c2)OCCO3)c2ccccc2c1=O
c.) Cc1nn(Cc2ccccc2Cl)c(C)c1C(=O)N1CCN(c2ccccc2)CC1
d.) COC(=O)C1C(=O)CC(C)(O)C(C(=O)OC)C1c1ccccc1F
e.) C(=Nc1ccc(N2CCOCC2)cc1)c1c[nH]c2ccccc12
Answer: c. Cc1nn(Cc2ccccc2Cl)c(C)c1C(=O)N1CCN(c2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1nn(Cc2ccccc2Cl)c(C)c1C(=O)N1CCN(c2ccccc2)CC1
Cc1nn(Cc2ccccc2Cl)c(C)c1C(=O)N1CCN(c2ccccc2)CC1
[2-[(2-chlorophenyl)methyl]-3,5-dimethylpyrazol-4-yl]-(4-phenylpiperazin-1-yl)methanone