Problem statement: Answer the MCQ question.
Query: Which compound has a -16.187\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CCOC(=O)C1(CCCc2ccccc2)CCN(C(=O)CCc2cnccn2)CC1
b Cc1nc2ccc(C(=O)c3ccccc3)cc2[nH]1
c CNC(=O)COc1ccc2oc3c(c2c1)CCCC3
d NC(=O)c1ccc(NC(=O)c2ccc(CN3CCOCC3)cc2)cc1
e Cl.O=C(O)CC1(CC(=O)N2CCN(CCO)CC2)CCCC1
Answer: a. CCOC(=O)C1(CCCc2ccccc2)CCN(C(=O)CCc2cnccn2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1(CCCc2ccccc2)CCN(C(=O)CCc2cnccn2)CC1
CCOC(=O)C1(CCCc2ccccc2)CCN(C(=O)CCc2cnccn2)CC1
ethyl 4-(3-phenylpropyl)-1-(3-pyrazin-2-ylpropanoyl)piperidine-4-carboxylate