Problem statement: Answer the multiple choice question.
Query: Which compound has a -1.220\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CC(C)N1CC(C(=O)Nc2cccc([N+](=O)[O-])c2)CC1=O
[b] COc1ccc2c(CC(=O)N[C@@H](Cc3ccccc3)C(=O)O)cc(=O)oc2c1C
[c] Cc1ccc(SCC(=O)OCC(=O)NC(C)c2ccc(Br)cc2)cc1
[d] Nc1c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc2n1/N=C/c1ccco1
[e] COc1cccc(CN2CC(C(=O)NCCC3=CCCCC3)CCC2=O)c1
Answer: e. COc1cccc(CN2CC(C(=O)NCCC3=CCCCC3)CCC2=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CN2CC(C(=O)NCCC3=CCCCC3)CCC2=O)c1
COc1cccc(CN2CC(C(=O)NCCC3=CCCCC3)CCC2=O)c1
N-[2-(cyclohexen-1-yl)ethyl]-1-[(3-methoxyphenyl)methyl]-6-oxopiperidine-3-carboxamide