Task: Answer the multiple-choice question.
Query: Which drug has a 12.688\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C(O)c1ccc(S(=O)(=O)Nc2cccc(CP(=O)(c3ccccc3)c3ccccc3)c2)cc1
b) COc1ccc(C(=O)NCC(=O)NCc2cc(=O)n(C)c(=O)n2C)cc1
c) COc1ccccc1C1=NN(C2=NN=C(N)Cc3ncnn32)C(O)(C(F)(F)F)C1
d) COc1ccc(-c2[nH]ncc2CNC(C)Cc2cccc(C)n2)cc1F
e) O=C(CC1SC(=O)N(c2ccccc2)C1=O)Nc1ccccc1
Answer: c. COc1ccccc1C1=NN(C2=NN=C(N)Cc3ncnn32)C(O)(C(F)(F)F)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1C1=NN(C2=NN=C(N)Cc3ncnn32)C(O)(C(F)(F)F)C1
COc1ccccc1C1=NN(C2=NN=C(N)Cc3ncnn32)C(O)(C(F)(F)F)C1
2-(8-amino-9H-[1,2,4]triazolo[1,5-d][1,2,4]triazepin-5-yl)-5-(2-methoxyphenyl)-3-(trifluoromethyl)-4H-pyrazol-3-ol