Problem statement: Answer the MCQ question.
Question: Which drug has a -84.491\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CC1CCN(S(=O)(=O)c2ccc(NC(=O)c3ccco3)cc2)CC1
b.) CCOC(=O)c1c(NC(=O)CC2SC(N)=NC2=O)sc2c1CCC(C)C2
c.) CCN(CC)c1ccc(NC(=O)CN2CCN(CC(=O)Nc3ccc(F)cc3)CC2)cc1
d.) CCOC(=O)C1(CCc2ccccc2)CCN(C(C)CSC)CC1
e.) CCOc1ccccc1C1C(C#N)=C(N)Oc2n[nH]c(CC)c21
Answer: c. CCN(CC)c1ccc(NC(=O)CN2CCN(CC(=O)Nc3ccc(F)cc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(CC)c1ccc(NC(=O)CN2CCN(CC(=O)Nc3ccc(F)cc3)CC2)cc1
CCN(CC)c1ccc(NC(=O)CN2CCN(CC(=O)Nc3ccc(F)cc3)CC2)cc1
2-[4-[2-[4-(diethylamino)anilino]-2-oxoethyl]piperazin-1-yl]-N-(4-fluorophenyl)acetamide