Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 5.168\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C1CN(C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](C(=O)O)c2ccccc2)c2ccccc2N1
b COc1ccc(-c2c(C(F)(F)F)nn(C)c2NC(C)=O)cc1
c Cl.O=C(Nc1cccc(F)c1)[C@@H]1CCCN1
d COc1ccc(C2C(C(=O)N3CCC4(CC3)OCCO4)CC(=O)N2c2ccc(OC)cc2)cc1
e O=C(c1cccs1)N1N=C(c2ccccc2)CC1c1ccccc1O
Answer: d. COc1ccc(C2C(C(=O)N3CCC4(CC3)OCCO4)CC(=O)N2c2ccc(OC)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2C(C(=O)N3CCC4(CC3)OCCO4)CC(=O)N2c2ccc(OC)cc2)cc1
COc1ccc(C2C(C(=O)N3CCC4(CC3)OCCO4)CC(=O)N2c2ccc(OC)cc2)cc1
4-(1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl)-1,5-bis(4-methoxyphenyl)pyrrolidin-2-one