Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -44.724\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) C=CCSc1nc(-c2ccccc2)c2cc(Cl)ccc2n1
b.) COc1ccc(NC(=O)CCC(=O)OCc2ccc(C(=O)Oc3ccc(Cl)cc3)cc2)cc1
c.) Cc1cc(C(=O)OCC(=O)c2ccccc2)c2ccccc2n1
d.) Cc1ccc(C)c(SCC(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)c1
e.) CCc1ccc(CNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)nc1
Answer: e. CCc1ccc(CNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)nc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1ccc(CNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)nc1
CCc1ccc(CNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)nc1
1-[2-(4-chlorophenyl)ethyl]-N-[(5-ethylpyridin-2-yl)methyl]-6-oxopiperidine-3-carboxamide