Problem statement: Answer the multiple-choice question.
Query: Which compound has a -88.095\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Cc1cc(NC(=O)c2ccc3c(c2)C(=O)N(c2cccc(C)c2C)C3=O)no1
b.) COc1ccccc1C(=O)Nc1ccnn1C1CCN(CCCc2ccccc2)CC1
c.) O=C(CN1C(=O)c2ccccc2S1(=O)=O)c1ccc2c(c1)OCCCO2
d.) Fc1ccc(-c2nnc(CSc3nnc4ccccn34)o2)cc1
e.) COc1ccccc1CNC(=O)C(=O)c1cn(CC(=O)N2CCCC2)c2ccccc12
Answer: b. COc1ccccc1C(=O)Nc1ccnn1C1CCN(CCCc2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1C(=O)Nc1ccnn1C1CCN(CCCc2ccccc2)CC1
COc1ccccc1C(=O)Nc1ccnn1C1CCN(CCCc2ccccc2)CC1
2-methoxy-N-[2-[1-(3-phenylpropyl)piperidin-4-yl]pyrazol-3-yl]benzamide