Problem statement: Answer the multiple-choice question.
Query: Which drug has a -28.506\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O=C(c1ccco1)N1CCN(Cc2nc(-c3cccs3)no2)CC1
[b] Cc1ccc(/C=C/C(=O)NCCCc2ccccc2)cc1
[c] O=C(O)C1CC=C(Cl)CC1C(=O)NCC1OCCc2ccccc21
[d] O=C(NCc1ccccc1CN1CCCC1)C1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
[e] CCCC(=O)Nc1ccc(-c2csc(NNC(C)=O)n2)cc1
Answer: d. O=C(NCc1ccccc1CN1CCCC1)C1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCc1ccccc1CN1CCCC1)C1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
O=C(NCc1ccccc1CN1CCCC1)C1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
1-(4-chlorophenyl)sulfonyl-N-[[2-(pyrrolidin-1-ylmethyl)phenyl]methyl]piperidine-4-carboxamide