Problem statement: Answer the MCQ question.
Question: Which compound has a -8.439\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccccc1NC(=O)Cn1c(C)nc2c(sc(=S)n2Cc2ccco2)c1=O
b. CN(C(=O)Cn1cccc1C1=NC(c2ccccc2)CO1)c1ccccc1
c. COc1ccc(CN2CCNCC2)cc1.Cl
d. COc1ccc(C2=NN(CCC(=O)NCc3cccs3)C(=O)CC2)cc1
e. NC(=O)C1CCN(CCC(=O)Nc2ccc(F)c(F)c2)CC1
Answer: a. COc1ccccc1NC(=O)Cn1c(C)nc2c(sc(=S)n2Cc2ccco2)c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1NC(=O)Cn1c(C)nc2c(sc(=S)n2Cc2ccco2)c1=O
COc1ccccc1NC(=O)Cn1c(C)nc2c(sc(=S)n2Cc2ccco2)c1=O
2-[3-(furan-2-ylmethyl)-5-methyl-7-oxo-2-sulfanylidene-[1,3]thiazolo[4,5-d]pyrimidin-6-yl]-N-(2-methoxyphenyl)acetamide