Problem statement: Answer the multiple-choice question.
Query: Which drug has a 8.976\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1ccc(-c2cc3nc(C)cc(N4CC(C)CC(C)C4)n3n2)cc1
b: Cc1cc2c(cc1S(=O)(=O)N1CCN(c3ccccc3)CC1)OCC(=O)N2
c: O=C(CCl)NCCCN(C(=O)C(Cl)Cl)c1ccc([N+](=O)[O-])cc1
d: O=C(O)c1ccc(O)c(N2C(=O)Nc3ccccc3N2O)c1
e: CNC(=O)/C(=C\c1ccco1)NC(=O)c1ccco1
Answer: a. COc1ccc(-c2cc3nc(C)cc(N4CC(C)CC(C)C4)n3n2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2cc3nc(C)cc(N4CC(C)CC(C)C4)n3n2)cc1
COc1ccc(-c2cc3nc(C)cc(N4CC(C)CC(C)C4)n3n2)cc1
7-(3,5-dimethylpiperidin-1-yl)-2-(4-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidine