Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -3.885\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CC(CNC(=O)c1ccc(OC2CCN(Cc3ccccn3)CC2)cc1)Oc1cccnc1
b. Cc1cc(OCC(=O)NCc2ccncc2)c2c3c(c(=O)oc2c1)CCCC3
c. COC(=O)c1cc(S(=O)(=O)Nc2cccc(S(N)(=O)=O)c2)oc1C
d. Cn1c(=O)c2c(nc(N3CCc4ccccc4C3)n2C)n(C)c1=O
e. COc1ccccc1CN1C(=O)[C@@H]2C(CCC(N)=O)NC3(C(=O)Nc4c3ccc(Cl)c4C)[C@@H]2C1=O
Answer: d. Cn1c(=O)c2c(nc(N3CCc4ccccc4C3)n2C)n(C)c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cn1c(=O)c2c(nc(N3CCc4ccccc4C3)n2C)n(C)c1=O
Cn1c(=O)c2c(nc(N3CCc4ccccc4C3)n2C)n(C)c1=O
8-(3,4-dihydro-1H-isoquinolin-2-yl)-1,3,7-trimethylpurine-2,6-dione