Task: Answer the multiple choice question.
Question: Which drug exhibits a 12.780\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1ccc(Nc2nc(N)c3ccccc3n2)cc1C.Cl
b. Cc1cccc(-c2nnc(SCC(=O)C(C)(C)C)n2C)c1
c. COc1ccc(CCNC(=O)CSc2nc3[nH]ncc3c(=O)n2-c2cccc(C(F)(F)F)c2)cc1OC
d. C[C@@H]1CC2OC(=O)[C@@]3(C)C(=O)CC[C@@](C)(C23)[C@@]1(O)CCc1ccoc1
e. Cc1ccccc1-c1nc(CS(=O)(=O)CC(=O)N2CCOCC2)c(C)o1
Answer: d. C[C@@H]1CC2OC(=O)[C@@]3(C)C(=O)CC[C@@](C)(C23)[C@@]1(O)CCc1ccoc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C[C@@H]1CC2OC(=O)[C@@]3(C)C(=O)CC[C@@](C)(C23)[C@@]1(O)CCc1ccoc1
C[C@@H]1CC2OC(=O)[C@@]3(C)C(=O)CC[C@@](C)(C23)[C@@]1(O)CCc1ccoc1
(4R,8S,9R,10R)-9-[2-(furan-3-yl)ethyl]-9-hydroxy-4,8,10-trimethyl-2-oxatricyclo[6.3.1.04,12]dodecane-3,5-dione