Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 11.721\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Cc1ccc(-c2nn3c(C)nnc3s2)cc1N
(b) Cc1cc(S(=O)(=O)N2CCCC2)ccc1OCC(=O)NCc1ccco1
(c) O=C(CSc1nnc(-c2ccccn2)n1Cc1ccco1)c1ccc(Cl)cc1
(d) CN(C)CCCN(C(=O)COc1ccccc1)c1nc2c(Cl)cccc2s1.Cl
(e) COC(=O)C(Cc1cnc(Cl)s1)(C(=O)OC)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]
Answer: e. COC(=O)C(Cc1cnc(Cl)s1)(C(=O)OC)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C(Cc1cnc(Cl)s1)(C(=O)OC)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]
COC(=O)C(Cc1cnc(Cl)s1)(C(=O)OC)c1ccc(C(F)(F)F)cc1[N+](=O)[O-]
dimethyl 2-[(2-chloro-1,3-thiazol-5-yl)methyl]-2-[2-nitro-4-(trifluoromethyl)phenyl]propanedioate