Problem statement: Answer the MCQ question.
Question: Which compound has a -54.096\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] COc1ccc(CNC(=O)c2cc(SC)ccc2Cl)cc1OC
[b] O=C(CC1SC(N2CCCC2)=NC1=O)Nc1ccc(C(=O)N2CCN(c3cccc(Cl)c3)CC2)cc1
[c] Cc1ccc(NC(=O)CSc2nnc(C)n2-c2ccccc2)cc1
[d] O=C(C1CCCN1S(=O)(=O)c1cccc2nsnc12)N1CCN(c2ccc(F)cc2)CC1
Answer: d. O=C(C1CCCN1S(=O)(=O)c1cccc2nsnc12)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(C1CCCN1S(=O)(=O)c1cccc2nsnc12)N1CCN(c2ccc(F)cc2)CC1
O=C(C1CCCN1S(=O)(=O)c1cccc2nsnc12)N1CCN(c2ccc(F)cc2)CC1
[1-(2,1,3-benzothiadiazol-4-ylsulfonyl)pyrrolidin-2-yl]-[4-(4-fluorophenyl)piperazin-1-yl]methanone