Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 12.188\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(CN1C(=O)NC(Cc2c[nH]c3ccccc23)C1=O)Nc1ccc(F)c(F)c1F
b. COc1ccc(C2SCC(=O)N2Nc2ncc(Cl)cc2Cl)cc1
c. COC(=O)c1sccc1NC(=O)/C=C/c1ccc(Cl)cc1Cl
d. CCOC(=O)[C@H]1[C@H]2COc3ccc(OC)cc3[C@@H]2N2C(=O)CN(CC3CCCO3)C(=O)[C@@]12C
e. O=C(Nc1c(C(=O)N2CCOCC2)cnn1-c1ccccc1)c1ccc(F)cc1
Answer: e. O=C(Nc1c(C(=O)N2CCOCC2)cnn1-c1ccccc1)c1ccc(F)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1c(C(=O)N2CCOCC2)cnn1-c1ccccc1)c1ccc(F)cc1
O=C(Nc1c(C(=O)N2CCOCC2)cnn1-c1ccccc1)c1ccc(F)cc1
4-fluoro-N-[4-(morpholine-4-carbonyl)-2-phenylpyrazol-3-yl]benzamide