Task: Answer the multiple-choice question.
Query: Which drug has a -2.269\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CC(OC(=O)C1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)C(=O)NC1CCCCC1C
b. COc1cc(CNCCNCC(C)O)ccc1OCc1ccc(Cl)nc1
c. COc1ccc(N2CCN(C(=O)CC(C)S(=O)(=O)c3ccc4c(c3)NC(=O)CO4)CC2)cc1
d. Cc1ccnc(NC(=S)NC(=O)/C=C/c2ccco2)c1
e. O=C1NC(=O)C(=Cc2cccc(OCCOc3ccccc3)c2)C(=O)N1
Answer: b. COc1cc(CNCCNCC(C)O)ccc1OCc1ccc(Cl)nc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(CNCCNCC(C)O)ccc1OCc1ccc(Cl)nc1
COc1cc(CNCCNCC(C)O)ccc1OCc1ccc(Cl)nc1
1-[2-[[4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl]methylamino]ethylamino]propan-2-ol