Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -10.221\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CC(C)Oc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)C1CCC1
b.) CC(C)Sc1nnc(-c2c[nH]c3ccccc23)n1C
c.) Cc1ccc(NC(=O)CSCC(=O)Nc2ccccc2C(=O)N2CCCCC2)cc1
d.) CCCOc1ccc(-c2nc(OCC)c3ccccc3n2)cc1
e.) C=CCn1c(SCC(=O)N2CCCC2)nc2scc(-c3cccs3)c2c1=O
Answer: e. C=CCn1c(SCC(=O)N2CCCC2)nc2scc(-c3cccs3)c2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C=CCn1c(SCC(=O)N2CCCC2)nc2scc(-c3cccs3)c2c1=O
C=CCn1c(SCC(=O)N2CCCC2)nc2scc(-c3cccs3)c2c1=O
2-(2-oxo-2-pyrrolidin-1-ylethyl)sulfanyl-3-prop-2-enyl-5-thiophen-2-ylthieno[2,3-d]pyrimidin-4-one