Task: Answer the multiple-choice question.
Query: What is the human ether-à-go-go related gene (hERG) inhibition at 1uM of a compound with the SMILES COc1cc2c(cc1OC)C(C)N(C(=O)Cn1ncc3c1-c1cc(C)ccc1OC3)CC2?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) 8.479
(b) 15.333
(c) 8.164
(d) -2.242
(e) -6.144
Answer: e. -6.144\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COc1cc2c(cc1OC)C(C)N(C(=O)Cn1ncc3c1-c1cc(C)ccc1OC3)CC2
COc1cc2c(cc1OC)C(C)N(C(=O)Cn1ncc3c1-c1cc(C)ccc1OC3)CC2
1-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)-2-(8-methyl-4H-chromeno[4,3-c]pyrazol-1-yl)ethanone