Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a 12.680\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COC(=O)C1=CN(C2CCCCC2)C=C(C(=O)OC)C1c1ccc2c(c1)OCO2
(b) Cc1cc(/N=C/N(C)C)on1
(c) CC(NC(=O)c1cncc(Br)c1)c1ccc(S(N)(=O)=O)cc1
(d) CCOc1ccc(NC(=S)NC23CC4CC(CC(C4)C2)C3)cc1
(e) COc1ccc(Cn2nnnc2C(c2cc3cccc(C)c3[nH]c2=O)N2CCN(C)CC2)cc1
Answer: e. COc1ccc(Cn2nnnc2C(c2cc3cccc(C)c3[nH]c2=O)N2CCN(C)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(Cn2nnnc2C(c2cc3cccc(C)c3[nH]c2=O)N2CCN(C)CC2)cc1
COc1ccc(Cn2nnnc2C(c2cc3cccc(C)c3[nH]c2=O)N2CCN(C)CC2)cc1
3-[[1-[(4-methoxyphenyl)methyl]tetrazol-5-yl]-(4-methylpiperazin-1-yl)methyl]-8-methyl-1H-quinolin-2-one