Task: Answer the MCQ question.
Question: Which drug has a 8.783\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCn1c(O)c(/C(C)=N/N2CCCCC2c2cccnc2)c(=O)[nH]c1=S
b.) CCOc1ccc(C(=O)CCC(=O)NCC(=O)Nc2c(C)cccc2C)cc1
c.) Cc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCOCC3)CC2)cc1C
d.) COc1ccc(NC(=O)CCC(=O)N(Cc2ccc(OC)c(OC)c2)c2nccs2)c(OC)c1
e.) COc1ccc(CN2[C@@H](CC(=O)O)c3cc(C(F)(F)F)ccc3S2(=O)=O)cc1
Answer: c. Cc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCOCC3)CC2)cc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCOCC3)CC2)cc1C
Cc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCOCC3)CC2)cc1C
1-(3,4-dimethylphenyl)sulfonyl-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]piperidine-4-carboxamide