Problem statement: Answer the multiple-choice question.
Query: Which drug has a -10.568\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
(a) COC(=O)[C@H]1C[C@@H](c2ccccc2)[C@H](C)C1(C)C
(b) COc1ccc(C(=O)N2CCN(C(=O)CCc3nnc(-c4ccsc4)o3)CC2)cc1
(c) CCC(OC(=O)c1ccco1)C(=O)NCc1ccc(OC)cc1
(d) Cc1cc(C)c2c(c1)/C(=N/NC(=S)Nc1ccc(F)cc1)CCC2
Answer: b. COc1ccc(C(=O)N2CCN(C(=O)CCc3nnc(-c4ccsc4)o3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)N2CCN(C(=O)CCc3nnc(-c4ccsc4)o3)CC2)cc1
COc1ccc(C(=O)N2CCN(C(=O)CCc3nnc(-c4ccsc4)o3)CC2)cc1
1-[4-(4-methoxybenzoyl)piperazin-1-yl]-3-(5-thiophen-3-yl-1,3,4-oxadiazol-2-yl)propan-1-one