Problem statement: Answer the multiple choice question.
Question: Which drug has a -6.127\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1cc(C)cc(NS(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C)c1
b) Cc1ccc2c(C(=O)CCl)c(C)[nH]c2c1
c) COc1ccccc1OCC(=O)Nc1c2c(nn1-c1ccc(C)cc1)CS(=O)(=O)C2
d) Cc1c(C(=O)N2CCOCC2)sc(NC(=O)C(C)C)c1C#N
e) CCC(C)(C)C1CCc2nc3ccccc3c(C(=O)OC(C)C(=O)Nc3c(C)n(C)n(-c4ccccc4)c3=O)c2C1
Answer: c. COc1ccccc1OCC(=O)Nc1c2c(nn1-c1ccc(C)cc1)CS(=O)(=O)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1OCC(=O)Nc1c2c(nn1-c1ccc(C)cc1)CS(=O)(=O)C2
COc1ccccc1OCC(=O)Nc1c2c(nn1-c1ccc(C)cc1)CS(=O)(=O)C2
2-(2-methoxyphenoxy)-N-[2-(4-methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide