Problem statement: Answer the multiple-choice question.
Question: Which drug has a 8.393\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) NS(=O)(=O)c1ccc(CCNC(=O)CSc2cccs2)cc1
b) CC(NC(=O)Nc1ccc(Cl)cc1)c1ccc2c(c1)OCO2
c) O=C1CN(c2nc(-c3cccnc3)nc3sc4c(c23)CCCC4)CCN1
d) CCOc1ccc(-c2csc3ncn(-c4ccc(OC)cc4)c(=O)c23)cc1
e) COc1ccc(CN(Cc2cccn2C)S(=O)(=O)c2ccccc2)cc1
Answer: d. CCOc1ccc(-c2csc3ncn(-c4ccc(OC)cc4)c(=O)c23)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(-c2csc3ncn(-c4ccc(OC)cc4)c(=O)c23)cc1
CCOc1ccc(-c2csc3ncn(-c4ccc(OC)cc4)c(=O)c23)cc1
5-(4-ethoxyphenyl)-3-(4-methoxyphenyl)thieno[2,3-d]pyrimidin-4-one