Problem statement: Answer the multiple-choice question.
Query: Which compound has a -4.716\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C(Nc1cccc([N+](=O)[O-])c1)N1CCN(c2ccccc2)CC1
(b) O=C(NCCC(=O)N1CCN(Cc2c(F)cccc2Cl)CC1)c1ccc(Cl)cc1
(c) CCOC(=O)c1c(C)n(C)c2ccc(O)c(CN3CCCCC3)c12
(d) Cc1ccc(NC(=O)C2CCCNC2=O)nc1
(e) CC(C)(C)NC(=O)/C=C/c1cccs1
Answer: b. O=C(NCCC(=O)N1CCN(Cc2c(F)cccc2Cl)CC1)c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCCC(=O)N1CCN(Cc2c(F)cccc2Cl)CC1)c1ccc(Cl)cc1
O=C(NCCC(=O)N1CCN(Cc2c(F)cccc2Cl)CC1)c1ccc(Cl)cc1
4-chloro-N-[3-[4-[(2-chloro-6-fluorophenyl)methyl]piperazin-1-yl]-3-oxopropyl]benzamide