Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 11.152\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(Cl)cc1-c1n[nH]c(=S)n1C1CCCCC1
b) COCCNC(=O)CN(C(=O)c1ccc(N2CCCC2)nc1)c1ccc(F)c(Cl)c1
c) COc1ccc(S(=O)(=O)N2CCN(CC(=O)NC3CCCC3)CC2)cc1
d) CCCCOC(=O)c1ccc(NC(=O)c2ocnc2C)cc1
e) Cc1ccc(CN(CC(=O)NCCc2ccccc2)C(=O)CCCC(=O)Nc2cc(C)on2)cc1
Answer: b. COCCNC(=O)CN(C(=O)c1ccc(N2CCCC2)nc1)c1ccc(F)c(Cl)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCNC(=O)CN(C(=O)c1ccc(N2CCCC2)nc1)c1ccc(F)c(Cl)c1
COCCNC(=O)CN(C(=O)c1ccc(N2CCCC2)nc1)c1ccc(F)c(Cl)c1
N-(3-chloro-4-fluorophenyl)-N-[2-(2-methoxyethylamino)-2-oxoethyl]-6-pyrrolidin-1-ylpyridine-3-carboxamide