Problem statement: Answer the multiple-choice question.
Question: Which compound has a 14.361\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O[C@@H]1CN(Cc2ccccc2Cl)CC[C@H]1N1CCOCC1
[b] Cl.O=C(CN1CCCCC1)Nc1ccc(NC(=O)c2ccccc2Cl)cc1Cl
[c] CN(CC(=O)Nc1ccc(F)cc1)C(=O)COC(=O)c1ccccc1
[d] COc1cc(C2NC(=O)CCC2[N+](=O)[O-])cc(Br)c1OC
[e] Cc1ccc(CNC(=O)c2ccc3c(=O)n(CC4CCCO4)c(=S)[nH]c3c2)cc1
Answer: a. O[C@@H]1CN(Cc2ccccc2Cl)CC[C@H]1N1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O[C@@H]1CN(Cc2ccccc2Cl)CC[C@H]1N1CCOCC1
O[C@@H]1CN(Cc2ccccc2Cl)CC[C@H]1N1CCOCC1
(3R,4R)-1-[(2-chlorophenyl)methyl]-4-morpholin-4-ylpiperidin-3-ol