Task: Answer the multiple choice question.
Question: Which drug exhibits a -2.011\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(N2CCN(C(=O)COC(=O)COc3cc(C)cc(C)c3)CC2)cc1
(b) O=C(CCc1ccc(S(=O)(=O)NCCc2ccccc2)cc1)NCc1ccc2c(c1)OCO2
(c) N#C[C@@H]1[C@@H]2C(=O)N(c3ccc4c(c3)OCCO4)C(=O)[C@@H]2C2c3ccccc3C=CN21
(d) CCN1CCN(CCC(=O)Nc2cc(OC)cc(OC)c2)CC1
(e) CC(C)(C)C(=O)Nc1cccc(-c2cc(-c3c(Cl)cccc3Cl)no2)c1
Answer: a. COc1ccc(N2CCN(C(=O)COC(=O)COc3cc(C)cc(C)c3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(C(=O)COC(=O)COc3cc(C)cc(C)c3)CC2)cc1
COc1ccc(N2CCN(C(=O)COC(=O)COc3cc(C)cc(C)c3)CC2)cc1
[2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl] 2-(3,5-dimethylphenoxy)acetate