Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -1.580\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCOCC(=O)Nc1cc(C)on1
b) Cc1ccc(-n2c(=O)c3sccc3n(CC(=O)NCc3ccco3)c2=O)cc1F
c) CC(=O)Nc1ccc(N(CC(=O)NCC2CCCO2)C(=O)CCC(=O)Nc2cc(C)on2)cc1
d) Cc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)o1
e) COc1ccc(OCC(=O)NCC(c2ccc(OC)cc2)N2CCCCC2)cc1
Answer: e. COc1ccc(OCC(=O)NCC(c2ccc(OC)cc2)N2CCCCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OCC(=O)NCC(c2ccc(OC)cc2)N2CCCCC2)cc1
COc1ccc(OCC(=O)NCC(c2ccc(OC)cc2)N2CCCCC2)cc1
2-(4-methoxyphenoxy)-N-[2-(4-methoxyphenyl)-2-piperidin-1-ylethyl]acetamide