Problem statement: Answer the MCQ question.
Query: Which drug has a -1.397\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COC(=O)c1ccc(OCC(=O)NC(C)(C)C)cc1
(b) CC1(C)Cc2c(C#N)c(NCCO)nc(-c3ccco3)c2CO1
(c) CCN(CC)C(=O)C1CCCN(Cc2nc(-c3cnccn3)no2)C1
(d) O=C1c2ccccc2C(=O)C1c1ccncc1
(e) O=C(COC(=O)COc1ccc(Cl)cc1)Nc1ccc2c(c1)OCCO2
Answer: c. CCN(CC)C(=O)C1CCCN(Cc2nc(-c3cnccn3)no2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(CC)C(=O)C1CCCN(Cc2nc(-c3cnccn3)no2)C1
CCN(CC)C(=O)C1CCCN(Cc2nc(-c3cnccn3)no2)C1
N,N-diethyl-1-[(3-pyrazin-2-yl-1,2,4-oxadiazol-5-yl)methyl]piperidine-3-carboxamide