Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a -20.342\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C1CCc2cc(S(=O)(=O)N3CCCC3C(=O)NC3CCCCCCC3)ccc2N1
b) COC(=O)CSc1snnc1-c1ccc(Cl)c(Cl)c1
c) Cc1ccc(CNC(=O)c2ccc(NC(=O)C3=CSCCO3)cc2)cc1
d) O=C(OCC(=O)N1CCN(C(=O)c2ccco2)CC1)c1ccccc1C(=O)c1ccccc1
e) CCN1CCN(C(=O)c2ccc(Cl)c(S(=O)(=O)N3CCCCCC3)c2)CC1.Cl
Answer: a. O=C1CCc2cc(S(=O)(=O)N3CCCC3C(=O)NC3CCCCCCC3)ccc2N1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1CCc2cc(S(=O)(=O)N3CCCC3C(=O)NC3CCCCCCC3)ccc2N1
O=C1CCc2cc(S(=O)(=O)N3CCCC3C(=O)NC3CCCCCCC3)ccc2N1
N-cyclooctyl-1-[(2-oxo-3,4-dihydro-1H-quinolin-6-yl)sulfonyl]pyrrolidine-2-carboxamide