Problem statement: Answer the MCQ question.
Question: Which compound exhibits a -22.002\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COC(=O)c1c(NC(=S)NNS(=O)(=O)c2ccc(OC)cc2OC)sc2c1CCCCCC2
b C/C(CC(=O)Nc1ccc(C)c(Cl)c1)=N\NC(=O)c1cccc(O)c1
c Cc1ccc(NC(=O)CCN2CC(C)OC(C)C2)cc1C.Cl
d O=C(N/N=C/c1nn(-c2ccccc2)cc1-c1ccccc1)c1ccncc1
e Cc1ccc(NC2CCCN(C(=O)CCc3ccncc3)C2)cc1C
Answer: a. COC(=O)c1c(NC(=S)NNS(=O)(=O)c2ccc(OC)cc2OC)sc2c1CCCCCC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1c(NC(=S)NNS(=O)(=O)c2ccc(OC)cc2OC)sc2c1CCCCCC2
COC(=O)c1c(NC(=S)NNS(=O)(=O)c2ccc(OC)cc2OC)sc2c1CCCCCC2
methyl 2-[[(2,4-dimethoxyphenyl)sulfonylamino]carbamothioylamino]-4,5,6,7,8,9-hexahydrocycloocta[b]thiophene-3-carboxylate