Problem statement: Answer the multiple choice question.
Question: Which drug has a -25.078\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1ccc(CCN=C2SCC(=O)N2C)cc1OC
b: O=[N+]([O-])c1cccc(C(=Nc2ccc(Cl)cc2)NO)c1
c: CCN1CCN(c2ccc(S(=O)(=O)N3CCCCC3)cc2NC(=O)c2cccc(C)c2[N+](=O)[O-])CC1
d: COc1ccc(CCn2c(C(C)C)nc3oc4ccccc4c(=O)c3c2=O)cc1
e: Cc1ccc(C)c(NC(=O)Cn2nc(C(F)(F)F)cc2C2CC2)c1
Answer: d. COc1ccc(CCn2c(C(C)C)nc3oc4ccccc4c(=O)c3c2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CCn2c(C(C)C)nc3oc4ccccc4c(=O)c3c2=O)cc1
COc1ccc(CCn2c(C(C)C)nc3oc4ccccc4c(=O)c3c2=O)cc1
3-[2-(4-methoxyphenyl)ethyl]-2-propan-2-ylchromeno[2,3-d]pyrimidine-4,5-dione