Problem statement: Answer the multiple-choice question.
Query: Which compound has a -1.233\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O.O=S(=O)(O)O
b: CCOc1ccccc1C(=O)NCC(=O)Nc1ncccc1C
c: COc1cc2nc(COc3ccc(C#N)cc3)n(CC#N)c(=O)c2cc1OC
d: COc1ccc2oc(C(=O)NCCc3ccccc3)c(C)c2c1
e: CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Nc2ccc(O)c(C(=O)O)c2)cc1
Answer: c. COc1cc2nc(COc3ccc(C#N)cc3)n(CC#N)c(=O)c2cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2nc(COc3ccc(C#N)cc3)n(CC#N)c(=O)c2cc1OC
COc1cc2nc(COc3ccc(C#N)cc3)n(CC#N)c(=O)c2cc1OC
4-[[3-(cyanomethyl)-6,7-dimethoxy-4-oxoquinazolin-2-yl]methoxy]benzonitrile