Problem statement: Answer the multiple-choice question.
Question: Which compound has a 16.122\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCN1CCN(c2nc3c(c(=O)[nH]c(=O)n3C)n2CCCc2ccccc2)CC1
b) CCO[C@H]1OC(C(=O)Nc2ccccc2)=C[C@@H](c2csc3ccccc23)[C@@H]1CCCO
c) COc1cc2c(cc1OC)C(c1cccc(Br)c1)NC(=O)C2
d) CCN(CC(=O)Nc1c(C(=O)OC)[nH]c2ccc(C)cc12)c1ccc2c(c1)OCO2
e) N=C1C(=O)OCC1c1ccccc1NC(=O)c1ccccc1
Answer: c. COc1cc2c(cc1OC)C(c1cccc(Br)c1)NC(=O)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(c1cccc(Br)c1)NC(=O)C2
COc1cc2c(cc1OC)C(c1cccc(Br)c1)NC(=O)C2
1-(3-bromophenyl)-6,7-dimethoxy-2,4-dihydro-1H-isoquinolin-3-one