Problem statement: Answer the MCQ question.
Question: Which compound has a 12.560\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C(Cn1ncc2c3ccccc3n(Cc3ccccc3)c2c1=O)NCc1ccccn1
b) CC(C)c1ccc(O)c(C(=O)c2cnn(-c3ccccc3)c2)c1
c) COc1cc(NC(=O)Cn2cnc(S(=O)(=O)N3CCCCC3)c2)cc(OC)c1OC
d) CSc1nc(S(=O)(=O)c2ccccc2)c(Cl)s1
e) CSc1nsc(SC)c1C(=O)Nc1ccc(C)cc1
Answer: e. CSc1nsc(SC)c1C(=O)Nc1ccc(C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CSc1nsc(SC)c1C(=O)Nc1ccc(C)cc1
CSc1nsc(SC)c1C(=O)Nc1ccc(C)cc1
N-(4-methylphenyl)-3,5-bis(methylsulfanyl)-1,2-thiazole-4-carboxamide