Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 13.706\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CC1CCc2nn(CC(=O)N3CCCCCC3)cc2C1
b) CCN(CC)CCNc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)s1
c) CC(C)Cc1nnc(NC(=O)C2CC(=O)N(c3ccc4c(c3)OCCO4)C2)s1
d) CCn1c(C)c(C(C)=O)c(NCc2ccccc2)nc1=S
e) COCCNC(=S)N(CCc1c(C)[nH]c2ccc(F)cc12)Cc1ccc(C)cc1
Answer: e. COCCNC(=S)N(CCc1c(C)[nH]c2ccc(F)cc12)Cc1ccc(C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCNC(=S)N(CCc1c(C)[nH]c2ccc(F)cc12)Cc1ccc(C)cc1
COCCNC(=S)N(CCc1c(C)[nH]c2ccc(F)cc12)Cc1ccc(C)cc1
1-[2-(5-fluoro-2-methyl-1H-indol-3-yl)ethyl]-3-(2-methoxyethyl)-1-[(4-methylphenyl)methyl]thiourea