Problem statement: Answer the multiple choice question.
Question: Which drug has a 17.439\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(COC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1)NCc1ccccc1
b. Cc1cccc(N2CCN(C(c3cccs3)c3nnnn3C(C)(C)C)CC2)c1C
c. COc1cc(NC(=O)c2cc([N+](=O)[O-])ccc2N2CCOCC2)ccc1NC(=O)c1ccco1
d. COCCn1nnnc1C(c1cccs1)N1CCN2CCCC2C1.Cl
e. CC1CCN(C(=O)CCC(=O)Nc2nnc(C(F)(F)F)s2)CC1
Answer: e. CC1CCN(C(=O)CCC(=O)Nc2nnc(C(F)(F)F)s2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1CCN(C(=O)CCC(=O)Nc2nnc(C(F)(F)F)s2)CC1
CC1CCN(C(=O)CCC(=O)Nc2nnc(C(F)(F)F)s2)CC1
4-(4-methylpiperidin-1-yl)-4-oxo-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]butanamide