Task: Answer the MCQ question.
Question: Which drug exhibits a 12.520\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccccc1C1=NN(C2=NN=C(N)Cc3ncnn32)C(O)(C(F)(F)F)C1
(b) COc1cc(OC)cc(-c2nc(=S)n3ccsc3n2)c1
(c) Cc1ccc(C(=O)CN(C(=O)c2ccc(Cl)c(Cl)c2)N2C(=O)C3C4C=CC(C4)C3C2=O)cc1
(d) C=CCc1c(C)nc2c(-c3ccccc3)cnn2c1N1CCOCC1
(e) Cc1noc(C)c1S(=O)(=O)N1CCC(C(=O)NC2CCCc3ccccc32)CC1
Answer: c. Cc1ccc(C(=O)CN(C(=O)c2ccc(Cl)c(Cl)c2)N2C(=O)C3C4C=CC(C4)C3C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(C(=O)CN(C(=O)c2ccc(Cl)c(Cl)c2)N2C(=O)C3C4C=CC(C4)C3C2=O)cc1
Cc1ccc(C(=O)CN(C(=O)c2ccc(Cl)c(Cl)c2)N2C(=O)C3C4C=CC(C4)C3C2=O)cc1
3,4-dichloro-N-(3,5-dioxo-4-azatricyclo[5.2.1.02,6]dec-8-en-4-yl)-N-[2-(4-methylphenyl)-2-oxoethyl]benzamide