Problem statement: Answer the MCQ question.
Question: Which compound exhibits a -9.498\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COC(=O)c1nn(-c2nc(-c3cccc(OC)c3)cc(C(F)(F)F)n2)cc1[N+](=O)[O-]
b.) COc1cc(CN2CCN(C(O)(c3ccccc3)c3ccccc3)CC2)cc(OC)c1OC.O=C(O)C(=O)O
c.) O=[N+]([O-])c1cc(S(=O)(=O)N2CCCC2)ccc1N/N=C/c1cccs1
d.) Cc1ccc(C(O)Cn2nc(C)cc2C)cc1
e.) COc1ccc(NC(=O)CCN2CCN(S(=O)(=O)c3ccc(Br)cc3)CC2)cc1
Answer: b. COc1cc(CN2CCN(C(O)(c3ccccc3)c3ccccc3)CC2)cc(OC)c1OC.O=C(O)C(=O)O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(CN2CCN(C(O)(c3ccccc3)c3ccccc3)CC2)cc(OC)c1OC.O=C(O)C(=O)O
COc1cc(CN2CCN(C(O)(c3ccccc3)c3ccccc3)CC2)cc(OC)c1OC.O=C(O)C(=O)O
diphenyl-[4-[(3,4,5-trimethoxyphenyl)methyl]piperazin-1-yl]methanol;oxalic acid