Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -5.136\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C(CC(=O)N/N=C/c1ccc(Cl)cc1Cl)NCc1ccccc1
[b] COc1ccccc1-n1c2nc3ccccc3nc2c2c(=O)n(-c3cc(C)cc(C)c3)cnc21
[c] Cl.NCCSSCCN
[d] CC(O)CCC(=O)NNC1CC(=O)N(c2ccccc2)C1=O
[e] CCCCCC(=O)N/N=C(\C)c1ccccn1
Answer: b. COc1ccccc1-n1c2nc3ccccc3nc2c2c(=O)n(-c3cc(C)cc(C)c3)cnc21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1-n1c2nc3ccccc3nc2c2c(=O)n(-c3cc(C)cc(C)c3)cnc21
COc1ccccc1-n1c2nc3ccccc3nc2c2c(=O)n(-c3cc(C)cc(C)c3)cnc21
13-(3,5-dimethylphenyl)-17-(2-methoxyphenyl)-2,9,13,15,17-pentazatetracyclo[8.7.0.03,8.011,16]heptadeca-1,3,5,7,9,11(16),14-heptaen-12-one