Problem statement: Answer the multiple-choice question.
Question: Which compound has a -6.073\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CCOC(=O)c1ccccc1NC(=O)N[C@@H](C)C(=O)OC
b: Cc1cnc(C(=O)OCC(=O)Nc2sc3c(c2C(N)=O)CCCC3)cn1
c: COC(=O)c1cc(S(=O)(=O)NCC2CCN(CCc3cccs3)CC2)cn1C
d: COC(=O)c1sc(NC(=O)c2ccncc2)nc1C
e: C=CCn1c(O)c(C=NCCCOc2ccc(CC)cc2)c(=O)[nH]c1=S
Answer: c. COC(=O)c1cc(S(=O)(=O)NCC2CCN(CCc3cccs3)CC2)cn1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cc(S(=O)(=O)NCC2CCN(CCc3cccs3)CC2)cn1C
COC(=O)c1cc(S(=O)(=O)NCC2CCN(CCc3cccs3)CC2)cn1C
methyl1-methyl-3-[[1-(2-thiophen-2-ylethyl)piperidin-4-yl]methylsulfamoyl]pyrrole-5-carboxylate