Problem statement: Answer the multiple choice question.
Question: Which drug has a -25.770\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CC(=NCCCN1CCCCC1)c1c(O)n(Cc2ccccc2)c(=O)[nH]c1=O
[b] Cc1ccc(NC(=O)Cn2cnc3c(cnn3C(C)(C)C)c2=O)cc1
[c] COc1ccccc1C(=O)N1CCN(c2ccc(N3CCOCC3)nn2)CC1
[d] CCOc1ccc(C(=O)NCC(=O)N2CCC3CCCCC3C2)cc1OCC
[e] CCCCCN(C(=O)CN(C)Cc1ccc(OC)cc1OC)c1c(N)n(CCCC)c(=O)[nH]c1=O
Answer: a. CC(=NCCCN1CCCCC1)c1c(O)n(Cc2ccccc2)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=NCCCN1CCCCC1)c1c(O)n(Cc2ccccc2)c(=O)[nH]c1=O
CC(=NCCCN1CCCCC1)c1c(O)n(Cc2ccccc2)c(=O)[nH]c1=O
1-benzyl-6-hydroxy-5-[C-methyl-N-(3-piperidin-1-ylpropyl)carbonimidoyl]pyrimidine-2,4-dione