Problem statement: Answer the MCQ question.
Query: Which drug has a -5.682\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a S=C(NCCCN1CCOCC1)NCCCN1CCOCC1
b CCOc1ccccc1N1CC(C(=O)Nc2cc(Cl)ccc2-n2cncn2)CC1=O
c CCOC(=O)C1CCN(C(=O)c2cc(CN3C(=O)c4ccccc4C3=O)ccc2OCC)CC1
d COc1cc(Cl)c(CC(=O)c2c[nH]c3ccccc23)cc1OC
e CS(=O)(=O)N(CC(=O)N1CCCCC1)c1ccc2c(c1)OCO2
Answer: c. CCOC(=O)C1CCN(C(=O)c2cc(CN3C(=O)c4ccccc4C3=O)ccc2OCC)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1CCN(C(=O)c2cc(CN3C(=O)c4ccccc4C3=O)ccc2OCC)CC1
CCOC(=O)C1CCN(C(=O)c2cc(CN3C(=O)c4ccccc4C3=O)ccc2OCC)CC1
ethyl 1-[5-[(1,3-dioxoisoindol-2-yl)methyl]-2-ethoxybenzoyl]piperidine-4-carboxylate