Problem statement: Answer the multiple choice question.
Question: Which compound has a -13.358\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(O)CSCC(=O)N1CCCN(c2ccc(C(F)(F)F)cn2)CC1
b. Cc1[nH]c2ccccc2c1C(c1ccncc1)N1CCCCC1
c. COC(=O)c1cc(OC)c(OC)cc1NC(=O)CSc1nnc(-c2cccnc2)n1C
d. OCC[C@@H]1C[C@@H](O)[C@H](O)[C@]2(OCCc3ccccc32)O1
e. FC(F)(F)c1cccc(N2CCN(c3ccc4nnc(-c5ccccc5)n4n3)CC2)c1
Answer: e. FC(F)(F)c1cccc(N2CCN(c3ccc4nnc(-c5ccccc5)n4n3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
FC(F)(F)c1cccc(N2CCN(c3ccc4nnc(-c5ccccc5)n4n3)CC2)c1
FC(F)(F)c1cccc(N2CCN(c3ccc4nnc(-c5ccccc5)n4n3)CC2)c1
3-phenyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-[1,2,4]triazolo[4,3-b]pyridazine