Problem statement: Answer the multiple-choice question.
Question: Which drug has a 8.547\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1ccc(C(=O)CCS(=O)(=O)c2ccc(C)cc2)cc1
b.) COC(=O)[C@H](CCSC)NC(=O)Nc1ccc(OC)cc1
c.) Cc1ccc(C(=O)N/N=C/c2ccc(-c3cccc(Cl)c3)o2)cn1
d.) CCn1c(O)c(/C(C)=N/N2CCCCC2c2cccnc2)c(=O)[nH]c1=S
e.) COCCCN(C(=O)CSCc1ccc(C)cc1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O
Answer: a. COc1ccc(C(=O)CCS(=O)(=O)c2ccc(C)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)CCS(=O)(=O)c2ccc(C)cc2)cc1
COc1ccc(C(=O)CCS(=O)(=O)c2ccc(C)cc2)cc1
1-(4-methoxyphenyl)-3-(4-methylphenyl)sulfonylpropan-1-one