Task: Answer the multiple-choice question.
Question: Which drug has a -8.423\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a. CCn1c(CSc2nc(C)cc(C)n2)nnc1SCC(N)=O
b. O=C(NCC(=O)N(Cc1ccccc1)C(C(=O)NC1CCCCC1)c1ccco1)c1ccco1
c. COc1ccc(CN(C(=O)c2ccc(-c3ccccc3)[nH]2)C(C(=O)NCC2CCCO2)c2ccc(C)o2)cc1
Answer: c. COc1ccc(CN(C(=O)c2ccc(-c3ccccc3)[nH]2)C(C(=O)NCC2CCCO2)c2ccc(C)o2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CN(C(=O)c2ccc(-c3ccccc3)[nH]2)C(C(=O)NCC2CCCO2)c2ccc(C)o2)cc1
COc1ccc(CN(C(=O)c2ccc(-c3ccccc3)[nH]2)C(C(=O)NCC2CCCO2)c2ccc(C)o2)cc1
N-[(4-methoxyphenyl)methyl]-N-[1-(5-methylfuran-2-yl)-2-oxo-2-(oxolan-2-ylmethylamino)ethyl]-5-phenyl-1H-pyrrole-2-carboxamide