Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 4.827\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1cccc(OCc2nnc(SCC(=O)N3CC(=O)Nc4ccccc43)o2)c1
b Cn1cc(CC(=O)Nc2cccc(C#N)c2)c2ccccc21
c C/C(=N\N=C1\NC(=O)C(CC(=O)Nc2ccc(Cl)cc2)S1)c1ccco1
d CN(C)N1C(N)=C(C#N)C(c2ccc(F)cc2)C2=C1CCCC2=O
e CCc1ccc(N2C(=O)CC(N3CCN(c4ccccn4)CC3)C2=O)cc1
Answer: d. CN(C)N1C(N)=C(C#N)C(c2ccc(F)cc2)C2=C1CCCC2=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(C)N1C(N)=C(C#N)C(c2ccc(F)cc2)C2=C1CCCC2=O
CN(C)N1C(N)=C(C#N)C(c2ccc(F)cc2)C2=C1CCCC2=O
2-amino-1-(dimethylamino)-4-(4-fluorophenyl)-5-oxo-4,6,7,8-tetrahydroquinoline-3-carbonitrile