Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 12.443\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCOC(=O)N1CCN(C(=O)C(=O)c2cn(CC(=O)N3CCCCCC3)c3ccccc23)CC1
b) O=C1CCN(C(=S)NCc2ccccc2)CC1
c) O=C(NCC12CC3CC(CC(C3)C1)C2)c1nn2c(c1Cl)NC(c1ccco1)CC2C(F)(F)F
d) CCCCN=C1NN=C(c2ccc(C)c(C)c2)CS1
e) CS(=O)(=O)N1CCC(C(=O)NCc2ccccc2)CC1
Answer: c. O=C(NCC12CC3CC(CC(C3)C1)C2)c1nn2c(c1Cl)NC(c1ccco1)CC2C(F)(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCC12CC3CC(CC(C3)C1)C2)c1nn2c(c1Cl)NC(c1ccco1)CC2C(F)(F)F
O=C(NCC12CC3CC(CC(C3)C1)C2)c1nn2c(c1Cl)NC(c1ccco1)CC2C(F)(F)F
N-(1-adamantylmethyl)-3-chloro-5-(furan-2-yl)-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxamide