Task: Answer the multiple-choice question.
Question: Which drug has a -3.184\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1nc(N/N=C/c2cc3c(cc2Br)OCO3)nc(N2CCOCC2)n1
b O=C(COC(=O)Cc1n[nH]c(=O)c2ccccc12)NNC(=O)c1ccc(Cl)cc1
c Cc1ccccc1-n1ncc(C(C)NC(=O)c2ccco2)c1C
d O=c1oc2ccccc2cc1-c1ccc(O)cc1O
e COc1cc2nc(=S)n(Cc3ccccc3Cl)c(N)c2cc1OC
Answer: b. O=C(COC(=O)Cc1n[nH]c(=O)c2ccccc12)NNC(=O)c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)Cc1n[nH]c(=O)c2ccccc12)NNC(=O)c1ccc(Cl)cc1
O=C(COC(=O)Cc1n[nH]c(=O)c2ccccc12)NNC(=O)c1ccc(Cl)cc1
[2-[2-(4-chlorobenzoyl)hydrazinyl]-2-oxoethyl]2-(4-oxo-3H-phthalazin-1-yl)acetate