Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 15.286\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] CC1CCCCN1C(=O)CN1CCC(c2nc3ccc(Cl)cc3[nH]2)CC1
[b] O=C(COC(=O)/C=C/c1ccc(Cl)cc1Cl)NCc1ccco1
[c] CC(C)(C)C1CCC(=NNc2ccc(S(N)(=O)=O)cc2[N+](=O)[O-])CC1
[d] CCOc1ccc(S(=O)(=O)N(C)CCO)cc1-c1nc2c(C(C)(C)C)nn(C)c2c(=O)[nH]1
Answer: d. CCOc1ccc(S(=O)(=O)N(C)CCO)cc1-c1nc2c(C(C)(C)C)nn(C)c2c(=O)[nH]1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(S(=O)(=O)N(C)CCO)cc1-c1nc2c(C(C)(C)C)nn(C)c2c(=O)[nH]1
CCOc1ccc(S(=O)(=O)N(C)CCO)cc1-c1nc2c(C(C)(C)C)nn(C)c2c(=O)[nH]1
3-(3-tert-butyl-1-methyl-7-oxo-6H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxy-N-(2-hydroxyethyl)-N-methylbenzenesulfonamide