Task: Answer the MCQ question.
Query: Which drug exhibits a -1.377\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: COc1cc(OC)cc(C(=O)NNC(=O)c2ccc(S(=O)(=O)N(C)c3ccccc3OC)cc2)c1
b: CC(C)(C)C(=O)N1CCN(c2nc3ccc(Br)cc3s2)CC1
c: COc1ccc(C(C)(C)C)cc1NC(=O)COC(=O)c1cnc(C)cn1
d: COc1ccc(CNS(=O)(=O)c2cc(-c3cc(C)no3)ccc2C(C)C)cc1
Answer: c. COc1ccc(C(C)(C)C)cc1NC(=O)COC(=O)c1cnc(C)cn1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(C)(C)C)cc1NC(=O)COC(=O)c1cnc(C)cn1
COc1ccc(C(C)(C)C)cc1NC(=O)COC(=O)c1cnc(C)cn1
[2-(5-tert-butyl-2-methoxyanilino)-2-oxoethyl] 5-methylpyrazine-2-carboxylate