Problem statement: Answer the multiple choice question.
Question: Which drug has a -21.083\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COCCSc1nnc(NC(=O)C2CC(=O)N(c3ccc(Cl)cc3)C2)s1
b COc1cc(C)ccc1OCCOCCOc1c(C)cc(C)cc1Br
c COc1ccc(C(CCN2CCCC2)c2c(O)cc(OC)cc2OC)cc1
d CCOC(=O)C(CC)(CCC(=O)O)c1csc(N)n1
e COC(=O)CC1COc2ccccc2N1C(=O)c1cccc(Cl)c1
Answer: c. COc1ccc(C(CCN2CCCC2)c2c(O)cc(OC)cc2OC)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(CCN2CCCC2)c2c(O)cc(OC)cc2OC)cc1
COc1ccc(C(CCN2CCCC2)c2c(O)cc(OC)cc2OC)cc1
3,5-dimethoxy-2-[1-(4-methoxyphenyl)-3-pyrrolidin-1-ylpropyl]phenol