Problem statement: Answer the MCQ question.
Question: Which compound has a 12.348\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
(a) COC(=O)NC1CCC(NC(=O)OC)CC1
(b) O=C(CCSCc1ccccc1)Nc1ccc2c(c1)OCCO2
(c) COc1ccccc1[C@@H]1C(c2cccc(Cl)c2)=NN(c2ccccc2)[C@H]1C(=O)N1CCOC1=O
(d) COc1ccc(/C=N/NC(=O)c2cccnc2)cc1CN1CCc2cc(OC)c(OC)cc2C1C
Answer: c. COc1ccccc1[C@@H]1C(c2cccc(Cl)c2)=NN(c2ccccc2)[C@H]1C(=O)N1CCOC1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1[C@@H]1C(c2cccc(Cl)c2)=NN(c2ccccc2)[C@H]1C(=O)N1CCOC1=O
COc1ccccc1[C@@H]1C(c2cccc(Cl)c2)=NN(c2ccccc2)[C@H]1C(=O)N1CCOC1=O
3-[(3R,4S)-5-(3-chlorophenyl)-4-(2-methoxyphenyl)-2-phenyl-3,4-dihydropyrazole-3-carbonyl]-1,3-oxazolidin-2-one