Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -12.678\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1cc2c(cc1OC)C(c1cccc(OC)c1OC)CC(=O)N2
b. CCCCOc1ccc(CN2CCCCC2)cc1
c. O=C1/C(=C/C=C/c2ccco2)SC(=S)N1NS(=O)(=O)c1ccccc1
d. CN(C)c1ccc(C(=O)N/N=C/c2cc(Br)cc(Br)c2O)cc1
e. Cc1cc(=O)oc2cc(OCC(=O)OCC(=O)Nc3ccc(C(C)C)cc3)ccc12
Answer: a. COc1cc2c(cc1OC)C(c1cccc(OC)c1OC)CC(=O)N2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(c1cccc(OC)c1OC)CC(=O)N2
COc1cc2c(cc1OC)C(c1cccc(OC)c1OC)CC(=O)N2
4-(2,3-dimethoxyphenyl)-6,7-dimethoxy-3,4-dihydro-1H-quinolin-2-one