Problem statement: Answer the MCQ question.
Query: Which compound has a 12.394\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) O=C(Nc1ccccc1)/C(=C/c1cccc(Br)c1)NC(=O)c1ccco1
b.) CCc1ccc2[nH]c(=O)c(C(c3nnnn3Cc3ccc(OC)cc3)N3CCOCC3)cc2c1
c.) Cc1ccc([C@@H]2[C@@H]3C(=O)N(c4ccccc4)C(=O)[C@@H]3[C@]3(C)C(=O)N(Cc4ccccn4)CC(=O)N23)o1
d.) CCOC(=O)C(Cc1ccc(NC(=O)/C(=C/c2ccc(OC(C)=O)cc2)NC(C)=O)cc1)N1C(=O)c2ccccc2C1=O
Answer: d. CCOC(=O)C(Cc1ccc(NC(=O)/C(=C/c2ccc(OC(C)=O)cc2)NC(C)=O)cc1)N1C(=O)c2ccccc2C1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C(Cc1ccc(NC(=O)/C(=C/c2ccc(OC(C)=O)cc2)NC(C)=O)cc1)N1C(=O)c2ccccc2C1=O
CCOC(=O)C(Cc1ccc(NC(=O)/C(=C/c2ccc(OC(C)=O)cc2)NC(C)=O)cc1)N1C(=O)c2ccccc2C1=O
ethyl 3-[4-[[(Z)-2-acetamido-3-(4-acetyloxyphenyl)prop-2-enoyl]amino]phenyl]-2-(1,3-dioxoisoindol-2-yl)propanoate