Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 9.791\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccccc1N(C(=O)c1ccco1)C(C(=O)NC1CCCCC1)c1cc(OC)c(OC)c(OC)c1
b: Cc1ccc(C)c(OCCC(=O)NNC(=O)c2ccccc2)c1
c: COc1ccc(CN2CC[C@H]3C=CC[C@@H](C(=O)N4CCOCC4)[C@H]3C2=O)cc1OC
d: Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCc4ccccc43)CC2)cc1
e: CC(NC(=O)CN(C)CC(=O)Nc1ccc(F)c(F)c1F)c1ccccc1
Answer: c. COc1ccc(CN2CC[C@H]3C=CC[C@@H](C(=O)N4CCOCC4)[C@H]3C2=O)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CN2CC[C@H]3C=CC[C@@H](C(=O)N4CCOCC4)[C@H]3C2=O)cc1OC
COc1ccc(CN2CC[C@H]3C=CC[C@@H](C(=O)N4CCOCC4)[C@H]3C2=O)cc1OC
(4aS,8R,8aS)-2-[(3,4-dimethoxyphenyl)methyl]-8-(morpholine-4-carbonyl)-3,4,4a,7,8,8a-hexahydroisoquinolin-1-one