Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a 5.224\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. Cc1cc(Cl)c2c(c1)C1(NC(CC(N)=O)[C@H]3C(=O)N(c4sc5c(c4C#N)CCCC5)C(=O)[C@H]31)C(=O)N2
b. CCOC(=O)N1CCN(Cc2cn[nH]c2-c2cccc3ccccc23)CC1
c. Cc1ccc(CNS(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1
d. COc1ccc(N2CCN(C(=O)Cn3cnc4c(cnn4-c4ccccc4)c3=O)CC2)cc1
Answer: d. COc1ccc(N2CCN(C(=O)Cn3cnc4c(cnn4-c4ccccc4)c3=O)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(C(=O)Cn3cnc4c(cnn4-c4ccccc4)c3=O)CC2)cc1
COc1ccc(N2CCN(C(=O)Cn3cnc4c(cnn4-c4ccccc4)c3=O)CC2)cc1
5-[2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]-1-phenylpyrazolo[3,4-d]pyrimidin-4-one