Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -18.461\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Cc1cc(C)cc(NC(=O)COC(=O)CN=C2NS(=O)(=O)c3ccccc32)c1
b.) COc1ccc(S(=O)(=O)N2CCC(NC(=O)c3cccnc3)CC2)cc1
c.) COc1cc(CN2CCN(C(=O)c3cccc4ccccc34)CC2)cc(OC)c1O.O=C(O)C(=O)O
d.) FC(F)(F)c1ccc(-n2cn[nH]c2=S)cc1
e.) CC(C)OC(=O)c1cccc2c1C(=O)c1ccccc1-2
Answer: b. COc1ccc(S(=O)(=O)N2CCC(NC(=O)c3cccnc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)N2CCC(NC(=O)c3cccnc3)CC2)cc1
COc1ccc(S(=O)(=O)N2CCC(NC(=O)c3cccnc3)CC2)cc1
N-[1-(4-methoxyphenyl)sulfonylpiperidin-4-yl]pyridine-3-carboxamide