Task: Answer the multiple-choice question.
Question: Which drug exhibits a -32.951\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Cc1cc2nc(CCN(C(=S)NCC3CCCO3)C3CCCC3)[nH]c2cc1C
(b) Cc1cc(C)n(NC(=S)NC(=O)CC(C)C)c(=O)c1C#N
(c) COc1cccc(C2c3[nH]c4ccccc4c3C[C@H]3C(=O)N(CCCCCO)CC(=O)N23)c1
(d) Br.CCN1C[C@]2(OC(=O)c3ccccc3NC(C)=O)CCC(OC)C34C5C[C@H]6C(OC)[C@]5(O)[C@](O)(C[C@@H]6OC)C(C[C@@H]32)[C@H]14
(e) c1ccc(-c2ccc3[nH]ccc3c2)cc1
Answer: c. COc1cccc(C2c3[nH]c4ccccc4c3C[C@H]3C(=O)N(CCCCCO)CC(=O)N23)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(C2c3[nH]c4ccccc4c3C[C@H]3C(=O)N(CCCCCO)CC(=O)N23)c1
COc1cccc(C2c3[nH]c4ccccc4c3C[C@H]3C(=O)N(CCCCCO)CC(=O)N23)c1
(8S)-6-(5-hydroxypentyl)-2-(3-methoxyphenyl)-3,6,17-triazatetracyclo[8.7.0.03,8.011,16]heptadeca-1(10),11,13,15-tetraene-4,7-dione