Task: Answer the multiple-choice question.
Question: Which compound exhibits a 9.578\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) C1COCCNCCOCCOCCOCCN1
b) COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCc2cc(OC)c(OC)cc2C1
c) Cc1cccc(C(=O)NC2CCN(C(=O)Nc3ccccc3C)CC2)c1
d) O=C(NC(=S)Nc1ccccc1N1CCOCC1)c1sc2ccccc2c1Cl
e) COCc1cc(C)[nH]c(=O)c1C(=O)NC12CC3CC(CC(C3)C1)C2
Answer: b. COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCc2cc(OC)c(OC)cc2C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCc2cc(OC)c(OC)cc2C1
COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCc2cc(OC)c(OC)cc2C1
methyl (1R,5S)-8-(6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbonyl)-3-(3,4-dimethoxyphenyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate