Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -1.982\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Nn1c(SCc2ccccc2)nnc1C1CCCCC1
b) O=C(C1CCCN(S(=O)(=O)c2ccc(Cl)cc2)C1)N1CCCC1
c) NS(=O)(=O)c1ccc(CCNC(=O)c2cc([N+](=O)[O-])ccc2N2CCCCC2)cc1
d) Nc1nc(NCc2ccco2)nc(N2CCCCC2)c1[N+](=O)[O-]
e) O=C(CNc1cccc(F)c1)N1CCc2ccccc2C1
Answer: b. O=C(C1CCCN(S(=O)(=O)c2ccc(Cl)cc2)C1)N1CCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(C1CCCN(S(=O)(=O)c2ccc(Cl)cc2)C1)N1CCCC1
O=C(C1CCCN(S(=O)(=O)c2ccc(Cl)cc2)C1)N1CCCC1
[1-(4-chlorophenyl)sulfonylpiperidin-3-yl]-pyrrolidin-1-ylmethanone