Task: Answer the multiple-choice question.
Question: Which drug has a -10.837\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. Cc1ccc(-n2c(O)c(C=Nc3ccc(S(N)(=O)=O)cc3)c(=O)[nH]c2=O)cc1
b. S=C(NC1CCCC1)N1CCN(c2ccc(Cl)cc2)CC1
c. CCCCOC(=O)c1ccc(NC(c2ccc(C)cc2)P(=O)(OC)OC)cc1
d. COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)N2CCN(C3CCS(=O)(=O)C3)CC2)c1
Answer: d. COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)N2CCN(C3CCS(=O)(=O)C3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)N2CCN(C3CCS(=O)(=O)C3)CC2)c1
COc1cccc(-c2nn(-c3ccc(C)cc3)cc2C(=O)N2CCN(C3CCS(=O)(=O)C3)CC2)c1
[4-(1,1-dioxothiolan-3-yl)piperazin-1-yl]-[3-(3-methoxyphenyl)-1-(4-methylphenyl)pyrazol-4-yl]methanone