Problem statement: Answer the multiple choice question.
Question: Which compound has a -1.058\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CC(C)C[C@H]1CN=C(Nc2ccccc2)N1CC1CCCC1
b: COc1ccc(NC(=O)c2c(C(F)(F)F)nn(C)c2Cl)cc1
c: CN1CCN(C(=O)C2=C[C@@H](c3csc4ccccc34)C[C@@H](OCc3ccc(CO)cc3)O2)CC1
d: CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(CC(=O)NCc2ccco2)c(=O)c2sccc21
e: Cc1ccc2c(c1)N1C(=O)c3ccccc3C1C1=C(CC(C)(C)CC1=O)N2
Answer: b. COc1ccc(NC(=O)c2c(C(F)(F)F)nn(C)c2Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)c2c(C(F)(F)F)nn(C)c2Cl)cc1
COc1ccc(NC(=O)c2c(C(F)(F)F)nn(C)c2Cl)cc1
5-chloro-N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)pyrazole-4-carboxamide