Problem statement: Answer the multiple choice question.
Query: Which compound exhibits a 8.386\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(NC(=O)c2ccc(N3C(=O)C4CC=C(Cl)CC4C3=O)cc2)cc1
b) Cc1cc(F)ccc1S(=O)(=O)N1CCCCC1CCNC(=O)C(=O)NCCN1CCOCC1
c) COc1ccccc1C(=O)NCC(=O)OC(C)C(=O)N(C)C1CCCCC1
d) Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)o1
e) N#CC(C#N)=c1s/c(=C/c2cn(-c3ccccc3)nc2-c2cccnc2)c(=O)n1-c1ccc(F)cc1
Answer: c. COc1ccccc1C(=O)NCC(=O)OC(C)C(=O)N(C)C1CCCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1C(=O)NCC(=O)OC(C)C(=O)N(C)C1CCCCC1
COc1ccccc1C(=O)NCC(=O)OC(C)C(=O)N(C)C1CCCCC1
[1-[cyclohexyl(methyl)amino]-1-oxopropan-2-yl] 2-[(2-methoxybenzoyl)amino]acetate