Problem statement: Answer the multiple-choice question.
Question: Which drug has a -6.140\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COC(=O)c1ccc(COC(=O)C2CCN(S(=O)(=O)c3c(Cl)cccc3Cl)CC2)o1
b: Cc1cc(O)c(/C=N/Nc2ccccc2)c(=O)o1
c: CCOc1ccc(N2CC(C(=O)Nc3cccc(S(=O)(=O)N4CCCCC4)c3)CC2=O)cc1
d: O=c1c2ccccc2nc(SCC2CCCCO2)n1-c1ccccc1
e: CC1CCCN(C(=O)CSc2nnc(-c3ccc(S(=O)(=O)N4CCOCC4)cc3)n2C)C1
Answer: a. COC(=O)c1ccc(COC(=O)C2CCN(S(=O)(=O)c3c(Cl)cccc3Cl)CC2)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(COC(=O)C2CCN(S(=O)(=O)c3c(Cl)cccc3Cl)CC2)o1
COC(=O)c1ccc(COC(=O)C2CCN(S(=O)(=O)c3c(Cl)cccc3Cl)CC2)o1
(5-methoxycarbonylfuran-2-yl)methyl 1-(2,6-dichlorophenyl)sulfonylpiperidine-4-carboxylate