Problem statement: Answer the MCQ question.
Query: Which drug has a 0.174\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(NCc1ccncc1)C(=O)NCc1ccco1
b.) COc1ccc(S(=O)(=O)CC(=O)c2cc3cc(Br)ccc3oc2=O)cc1
c.) Cc1ccnc(NC(c2ccsc2)c2ccc3ccc(C)nc3c2O)c1
d.) CCCOc1ccc(N2C(=O)CC(N(Cc3ccc(OC)cc3)C(=S)Nc3ccccc3)C2=O)cc1
e.) Cc1nc2sc3c(c2c(=O)o1)CC(C)(C)OC3
Answer: d. CCCOc1ccc(N2C(=O)CC(N(Cc3ccc(OC)cc3)C(=S)Nc3ccccc3)C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCOc1ccc(N2C(=O)CC(N(Cc3ccc(OC)cc3)C(=S)Nc3ccccc3)C2=O)cc1
CCCOc1ccc(N2C(=O)CC(N(Cc3ccc(OC)cc3)C(=S)Nc3ccccc3)C2=O)cc1
1-[2,5-dioxo-1-(4-propoxyphenyl)pyrrolidin-3-yl]-1-[(4-methoxyphenyl)methyl]-3-phenylthiourea