Problem statement: Answer the multiple-choice question.
Question: Which drug has a -14.462\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc(OCC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1
(b) CCCc1cc(=O)n2[nH]c(NCc3ccc(OC)c(OC)c3)nc2n1
(c) Cc1cccc(-n2ncc3c2CCCC3NC(=O)CCN2Cc3ccccc3C2=O)c1C
(d) CCCCN(C(=O)CSCc1c(C)noc1C)c1c(N)n(CCC)c(=O)[nH]c1=O
(e) CCN(CC#CCC(O)(c1ccccc1)C1CCCC1)CCO
Answer: a. COc1ccc(OCC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OCC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1
COc1ccc(OCC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1
1-[4-(furan-2-carbonyl)piperazin-1-yl]-2-(4-methoxyphenoxy)ethanone