Problem statement: Answer the MCQ question.
Query: Which drug has a 8.131\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1cc(CC(=O)Nc2cccc(SC)c2)cc(OC)c1OC
(b) COCCOC(=O)c1c(C)oc2ccc(O)c(CN3CCC(C)CC3)c12
(c) O=C(Nc1ccc(F)cc1F)C1CCCN1S(=O)(=O)c1ccc(-c2ccc(=O)[nH]n2)s1
(d) O=C(CCN1CCN(c2ccc(Cl)cc2)CC1)Nc1nccs1
(e) Cc1ccc(C(=O)N/C(=C\c2ccc(C)o2)C(=O)O)cc1
Answer: d. O=C(CCN1CCN(c2ccc(Cl)cc2)CC1)Nc1nccs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCN1CCN(c2ccc(Cl)cc2)CC1)Nc1nccs1
O=C(CCN1CCN(c2ccc(Cl)cc2)CC1)Nc1nccs1
3-[4-(4-chlorophenyl)piperazin-1-yl]-N-(1,3-thiazol-2-yl)propanamide