Problem statement: Answer the multiple-choice question.
Question: Which drug has a 8.519\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. CC[C@@]12C(=O)N(c3cccc(Cl)c3)C(=O)N1[C@H](c1ccc(Br)cc1)[C@@H]1C(=O)N(C(C)(C)C)C(=O)[C@@H]12
b. CCCC(=O)Nc1nc2c(OC)ccc(OC)c2s1
c. CC(C)(C)c1cc(=O)[nH]c(SCc2ccccc2Cl)n1
d. COc1ccc(NC(=O)CC2C(=O)N(c3ccc(F)cc3)C(=S)N2NC(=O)c2ccc(Cl)cc2)cc1
Answer: a. CC[C@@]12C(=O)N(c3cccc(Cl)c3)C(=O)N1[C@H](c1ccc(Br)cc1)[C@@H]1C(=O)N(C(C)(C)C)C(=O)[C@@H]12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC[C@@]12C(=O)N(c3cccc(Cl)c3)C(=O)N1[C@H](c1ccc(Br)cc1)[C@@H]1C(=O)N(C(C)(C)C)C(=O)[C@@H]12
CC[C@@]12C(=O)N(c3cccc(Cl)c3)C(=O)N1[C@H](c1ccc(Br)cc1)[C@@H]1C(=O)N(C(C)(C)C)C(=O)[C@@H]12
(1S,2R,7S,8R)-7-(4-bromophenyl)-10-tert-butyl-4-(3-chlorophenyl)-2-ethyl-4,6,10-triazatricyclo[6.3.0.02,6]undecane-3,5,9,11-tetrone