Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 7.224\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: FC(F)(F)c1ccc(CN2C[C@@H]3C(c4ccc(C(F)(F)F)cc4)C4(c5cccnc5)CC3(C4)[C@H]2c2ccccc2)cc1
b: CN(Cc1ccccc1)C(=O)COC(=O)c1ccc(Cl)cc1N
c: CN1C(=O)c2ccccc2Sc2ccc(C(=O)N3CCC4(CC3)OCCO4)cc21
d: O=S(=O)(c1ccc(F)c(F)c1)N1CCN(S(=O)(=O)c2cccs2)CC1
e: Cc1cccc(N2CCN(S(=O)(=O)c3ccc4c(c3)C(C)(C)C(=O)N4C)CC2C)c1
Answer: e. Cc1cccc(N2CCN(S(=O)(=O)c3ccc4c(c3)C(C)(C)C(=O)N4C)CC2C)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cccc(N2CCN(S(=O)(=O)c3ccc4c(c3)C(C)(C)C(=O)N4C)CC2C)c1
Cc1cccc(N2CCN(S(=O)(=O)c3ccc4c(c3)C(C)(C)C(=O)N4C)CC2C)c1
1,3,3-trimethyl-5-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]sulfonylindol-2-one