Problem statement: Answer the multiple choice question.
Question: Which drug has a -48.506\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) O=C(CCC1CCCN(c2ncccn2)C1)NCc1ccc(F)c(F)c1
(b) CCN(CC(=O)Nc1c(F)cccc1F)C(=O)c1ccc(-n2cncn2)c([N+](=O)[O-])c1
(c) C=CCN1C(=O)C(CC(=O)Nc2ccc(OCC)cc2)N(Cc2ccccn2)C1=S
(d) O=C(N/C=N/OCc1cccc(C(F)(F)F)c1)N1OC[C@@H]2COc3ccc4ccccc4c3[C@@H]21
(e) Cc1cc(C)c2c(CN3CCN(C)CC3)cc(=O)oc2c1
Answer: e. Cc1cc(C)c2c(CN3CCN(C)CC3)cc(=O)oc2c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cc(C)c2c(CN3CCN(C)CC3)cc(=O)oc2c1
Cc1cc(C)c2c(CN3CCN(C)CC3)cc(=O)oc2c1
5,7-dimethyl-4-[(4-methylpiperazin-1-yl)methyl]chromen-2-one