Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 8.651\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1ccc(NC2CCCN(C(=O)CCC(=O)c3ccc(F)cc3)C2)cc1
b: Cc1cnc(CNC(=O)c2ccc3oc(Cc4ccc(Cl)cc4)nc3c2)cn1
c: COc1ccc2c(c1)OC[C@H]1[C@H]2N2C(=O)CN(Cc3ccc(C)cc3)C(=O)[C@@]2(C)[C@H]1c1ccccc1
d: CN(C)Cc1c(O)ccc2c(=O)c(-c3ccccc3Cl)c(C(F)(F)F)oc12
e: COc1cc(Br)c(C(C)NC(=O)c2cccc(Br)c2)cc1OC
Answer: d. CN(C)Cc1c(O)ccc2c(=O)c(-c3ccccc3Cl)c(C(F)(F)F)oc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(C)Cc1c(O)ccc2c(=O)c(-c3ccccc3Cl)c(C(F)(F)F)oc12
CN(C)Cc1c(O)ccc2c(=O)c(-c3ccccc3Cl)c(C(F)(F)F)oc12
3-(2-chlorophenyl)-8-[(dimethylamino)methyl]-7-hydroxy-2-(trifluoromethyl)chromen-4-one