Problem statement: Answer the MCQ question.
Query: Which drug has a -5.455\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CCCc1cc(=O)oc2c(C)c(OCC(=O)NCCCn3ccnc3)ccc12
b: COC(C[C@@H]1O[C@@H]1[C@H](O)[C@@H](C)OCc1ccccc1)OC
c: CCN1C(=O)c2ccccc2Sc2ccc(C(=O)NCCCN3CCOCC3)cc21
d: CCn1c(COc2c(C)cccc2C)nnc1SCC(=O)N1CCN(c2ccccc2)CC1
e: CCOCCCNCc1cn(-c2ccc(F)cc2F)nc1-c1ccccc1C
Answer: e. CCOCCCNCc1cn(-c2ccc(F)cc2F)nc1-c1ccccc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOCCCNCc1cn(-c2ccc(F)cc2F)nc1-c1ccccc1C
CCOCCCNCc1cn(-c2ccc(F)cc2F)nc1-c1ccccc1C
N-[[1-(2,4-difluorophenyl)-3-(2-methylphenyl)pyrazol-4-yl]methyl]-3-ethoxypropan-1-amine