Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 0.161\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=c1[nH]c(=S)[nH]c2nc(-c3ccccc3)cnc12
b) FC(F)(F)c1cccc(Cc2noc(CN(Cc3ccccn3)CC3CCCO3)n2)c1
c) C=CCNC(=S)Nc1ccc(C)c(S(=O)(=O)N2CCCCC2)c1
d) Nc1nn(-c2ccccc2)c(N)c1N=Nc1ccc2c(c1)OCO2
e) Cc1cc(NC(=O)COC(=O)C2CCC(=O)N2)c([N+](=O)[O-])cc1C
Answer: c. C=CCNC(=S)Nc1ccc(C)c(S(=O)(=O)N2CCCCC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C=CCNC(=S)Nc1ccc(C)c(S(=O)(=O)N2CCCCC2)c1
C=CCNC(=S)Nc1ccc(C)c(S(=O)(=O)N2CCCCC2)c1
1-(4-methyl-3-piperidin-1-ylsulfonylphenyl)-3-prop-2-enylthiourea