Problem statement: Answer the multiple-choice question.
Question: Which drug has a 10.622\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1ccc2nc(NCCCNC(=O)c3cc(OC)c(OC)c(OC)c3)c(C#N)cc2c1
b CN1C(=O)c2ccccc2Sc2ccc(NC(=O)N3CCOCC3)cc21
c O=C(CCCC(=O)N(CC(=O)NC1CCCCC1)Cc1ccccc1)Nc1ccccn1
d Cc1ccc(N2CC(C(=O)Nc3c(C)n(C)n(-c4ccccc4)c3=O)CC2=O)cc1
e COc1ccc(NC2CCCN(C(=O)c3ccc(C(C)=O)s3)C2)cc1
Answer: d. Cc1ccc(N2CC(C(=O)Nc3c(C)n(C)n(-c4ccccc4)c3=O)CC2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(N2CC(C(=O)Nc3c(C)n(C)n(-c4ccccc4)c3=O)CC2=O)cc1
Cc1ccc(N2CC(C(=O)Nc3c(C)n(C)n(-c4ccccc4)c3=O)CC2=O)cc1
N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-1-(4-methylphenyl)-5-oxopyrrolidine-3-carboxamide