Task: Answer the MCQ question.
Query: Which drug exhibits a 10.374\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1cc(C(=O)Nc2ccc(Cl)c([N+](=O)[O-])c2)cc(OC)c1OC
(b) Cc1onc(-c2ccccc2Cl)c1C(=O)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1
(c) CCc1nnc(NC(=O)c2ccc(S(=O)(=O)N(CCOC)CCOC)cc2)s1
(d) CCc1ccc(C2C(C#N)=C(N)N(N3CCOCC3)C3=C2C(=O)CC(C)(C)C3)s1
(e) O=C(O)CCCC(=O)NCCc1ccncc1
Answer: d. CCc1ccc(C2C(C#N)=C(N)N(N3CCOCC3)C3=C2C(=O)CC(C)(C)C3)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1ccc(C2C(C#N)=C(N)N(N3CCOCC3)C3=C2C(=O)CC(C)(C)C3)s1
CCc1ccc(C2C(C#N)=C(N)N(N3CCOCC3)C3=C2C(=O)CC(C)(C)C3)s1
2-amino-4-(5-ethylthiophen-2-yl)-7,7-dimethyl-1-morpholin-4-yl-5-oxo-6,8-dihydro-4H-quinoline-3-carbonitrile