Problem statement: Answer the multiple choice question.
Question: Which compound has a 8.409\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCC(C)(C)NC(=O)CN(C(=O)c1snc(C(N)=O)c1N)c1ccc(OC)c(OC)c1
b) CCO[C@H]1OC(C(=O)N2CCCCCCC2)=C[C@@H](c2ccc(C(F)(F)F)cc2)[C@@H]1CCCO
c) C#Cc1ccc([C@@H]2C=C(C(=O)N3CCN(Cc4ccccc4)CC3)O[C@H](OCCCCO)C2)cc1
d) O=C(COC(=O)/C=C/c1cccs1)Nc1cccc(S(=O)(=O)N2CCOCC2)c1
e) CCN(CC(=O)NCc1ccccn1)S(=O)(=O)c1ccc(Cl)cc1
Answer: a. CCC(C)(C)NC(=O)CN(C(=O)c1snc(C(N)=O)c1N)c1ccc(OC)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC(C)(C)NC(=O)CN(C(=O)c1snc(C(N)=O)c1N)c1ccc(OC)c(OC)c1
CCC(C)(C)NC(=O)CN(C(=O)c1snc(C(N)=O)c1N)c1ccc(OC)c(OC)c1
4-amino-5-N-(3,4-dimethoxyphenyl)-5-N-[2-(2-methylbutan-2-ylamino)-2-oxoethyl]-1,2-thiazole-3,5-dicarboxamide