Task: Answer the multiple choice question.
Query: Which compound has a -11.780\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccccc1N1CCN(S(=O)(=O)c2c(C(=O)N3CCOCC3)c(C)n(C)c2C)CC1
(b) CCOCCCNC(=S)N1C2CCC1CC(NC(=O)NC13CC4CC(CC(C4)C1)C3)C2
(c) Cc1c(Cl)cccc1NC(=O)CCCN1C(=O)c2cccnc2C1=O
(d) CC(C(=O)NCC(=O)Nc1ccc(F)c(F)c1F)N1CCN(Cc2ccc(C#N)cc2)CC1
(e) O=[N+]([O-])/C=C1\NCCN1Cc1ccc(Cl)nc1
Answer: d. CC(C(=O)NCC(=O)Nc1ccc(F)c(F)c1F)N1CCN(Cc2ccc(C#N)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C(=O)NCC(=O)Nc1ccc(F)c(F)c1F)N1CCN(Cc2ccc(C#N)cc2)CC1
CC(C(=O)NCC(=O)Nc1ccc(F)c(F)c1F)N1CCN(Cc2ccc(C#N)cc2)CC1
2-[4-[(4-cyanophenyl)methyl]piperazin-1-yl]-N-[2-oxo-2-(2,3,4-trifluoroanilino)ethyl]propanamide