Problem statement: Answer the multiple-choice question.
Question: Which compound has a 4.570\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: Cc1ccc(-c2nn(-c3ccccc3)cc2C2CC(c3ccccc3)=NN2C(=O)CCC(=O)O)cc1
b: COc1ccc(CCNC(=O)CCN2C(=O)[C@@H]3Cc4ccccc4CN3C2=O)cc1OC
c: COc1ccc(-c2ccoc2)cc1[C@H]1[C@H]2C=CC[C@@H](C)[C@@H]2C(=O)N1Cc1ccccc1
d: C[C@@H]1CC[C@H]2C(=O)N3[C@@H](CC[C@@H](C)[C@@H]3c3ccc(Br)cc3)C(=O)N2[C@H]1c1ccc(Br)cc1
e: O=C(O)COc1ccccc1/C=N/NC(=O)c1ccc2c(c1)OCCO2
Answer: e. O=C(O)COc1ccccc1/C=N/NC(=O)c1ccc2c(c1)OCCO2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(O)COc1ccccc1/C=N/NC(=O)c1ccc2c(c1)OCCO2
O=C(O)COc1ccccc1/C=N/NC(=O)c1ccc2c(c1)OCCO2
2-[2-[(E)-(2,3-dihydro-1,4-benzodioxine-6-carbonylhydrazinylidene)methyl]phenoxy]acetic acid