Problem statement: Answer the multiple-choice question.
Question: Which drug has a 12.564\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: C=CCN1c2ccccc2[C@]23C[C@@H](C(=O)OC)N(C(=O)c4cc(C)oc4C)C2=NC(C(=O)OC)=C(C(=O)OC)[C@H]13
b: COC(=O)[C@@]12CCCCN1[C@H](c1ccc(-c3cc(C(C)=O)cs3)cc1)[C@H]1C(=O)N(C)C(=O)[C@H]12.O=C(O)C(F)(F)F
c: Cc1cc(C)cc(N(CC(=O)NC(C)(C)C)C(=O)CCC(=O)Nc2ccccn2)c1
d: O=C(Cn1nc(-c2ccc(Cl)cc2)ccc1=O)NCc1ccc2c(c1)OCO2
e: CCn1c(SCC(=O)Nc2nccs2)nnc1-c1ccccn1
Answer: d. O=C(Cn1nc(-c2ccc(Cl)cc2)ccc1=O)NCc1ccc2c(c1)OCO2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Cn1nc(-c2ccc(Cl)cc2)ccc1=O)NCc1ccc2c(c1)OCO2
O=C(Cn1nc(-c2ccc(Cl)cc2)ccc1=O)NCc1ccc2c(c1)OCO2
N-(1,3-benzodioxol-5-ylmethyl)-2-[3-(4-chlorophenyl)-6-oxopyridazin-1-yl]acetamide