Problem statement: Answer the MCQ question.
Query: Which compound has a 7.750\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1ccc(Oc2c(F)c(F)nc(N3CCCC3)c2F)cc1
b) COC(=O)c1ccc(NC(=O)C(=O)N2CCN(C(=S)Nc3ccc(OC)cc3)CC2)cc1
c) COC(=O)c1c(N2C(=O)CC(Sc3ccccc3C(=O)O)C2=O)sc(C)c1C
d) COc1ccc2[nH]c(=O)c(CN(c3ccc(C)c(C)c3)S(C)(=O)=O)cc2c1
e) COc1ccc(S(=O)(=O)NCC(=O)N(Cc2ccco2)C(C(=O)NC(C)(C)C)C(C)C)cc1
Answer: d. COc1ccc2[nH]c(=O)c(CN(c3ccc(C)c(C)c3)S(C)(=O)=O)cc2c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2[nH]c(=O)c(CN(c3ccc(C)c(C)c3)S(C)(=O)=O)cc2c1
COc1ccc2[nH]c(=O)c(CN(c3ccc(C)c(C)c3)S(C)(=O)=O)cc2c1
N-(3,4-dimethylphenyl)-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]methanesulfonamide