Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -1.223\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CCOc1ccc2oc(C(=O)Nc3cc(C)ccn3)c(C)c2c1
b: O=C(CSc1ccc2nnc(-c3ccccn3)n2n1)Nc1ccc(F)cc1
c: N#Cc1nc(-c2cccs2)oc1NCc1ccc2c(c1)OCO2
d: CS(=O)(=O)N(CC(=O)N1CCC(C(N)=O)CC1)c1ccc(Oc2ccccc2)cc1
e: CC(=O)C1=C(C)Nc2ncnn2C1c1ccc(C)cc1
Answer: b. O=C(CSc1ccc2nnc(-c3ccccn3)n2n1)Nc1ccc(F)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CSc1ccc2nnc(-c3ccccn3)n2n1)Nc1ccc(F)cc1
O=C(CSc1ccc2nnc(-c3ccccn3)n2n1)Nc1ccc(F)cc1
N-(4-fluorophenyl)-2-[(3-pyridin-2-yl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)sulfanyl]acetamide