Problem statement: Answer the multiple choice question.
Query: Which compound has a -3.513\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CC#CCN1c2ccccc2[C@]23C[C@@H](C(=O)OC)N(C(=O)NCCBr)C2=NC(C(=O)OC)=C(C(=O)OC)[C@H]13
b Cc1cc(C)cc(N2CN=c3s/c(=C\c4ccco4)c(=O)n3C2)c1
c C=CCn1c(SCC(=O)c2cc(C)n(CC3CCCO3)c2C)nc2sc(C)c(C)c2c1=O
d CS(=O)(=O)C1=NSC2=NC(=O)/C(=C\c3ccc(OC(=O)c4ccco4)cc3)C(=N)N21
e COc1ccc(CCC(=O)OCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1
Answer: e. COc1ccc(CCC(=O)OCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CCC(=O)OCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1
COc1ccc(CCC(=O)OCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1
[2-[(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)amino]-2-oxoethyl] 3-(4-methoxyphenyl)propanoate