Task: Answer the multiple choice question.
Question: Which drug exhibits a -0.259\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C(N[C@@H](Cc1ccccc1)C(=O)OCc1ccccc1)c1nc[nH]c1C(=O)N1CCc2ccccc2C1
b CCC(=O)c1ccc(N2CCCCC2)c(F)c1
c COc1ccc(CCNC(=O)c2cccs2)cc1
d COc1ccccc1N1CCN(C(=O)C2CCN(C(=O)c3ccccc3Cl)CC2)CC1
e O=[N+]([O-])c1ccc(Nc2nc(N/N=C\c3ccc4c(c3)OCO4)nc(N3CCCCC3)n2)cc1
Answer: d. COc1ccccc1N1CCN(C(=O)C2CCN(C(=O)c3ccccc3Cl)CC2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CCN(C(=O)C2CCN(C(=O)c3ccccc3Cl)CC2)CC1
COc1ccccc1N1CCN(C(=O)C2CCN(C(=O)c3ccccc3Cl)CC2)CC1
[1-(2-chlorobenzoyl)piperidin-4-yl]-[4-(2-methoxyphenyl)piperazin-1-yl]methanone