Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 12.564\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccc(C(=O)Nc2ccc(C(=O)NCC3CCCO3)cc2)c(OC)c1OC
b. COc1c(/C=C2\SC(=Nc3ccccc3Cl)NC2=O)cccc1[N+](=O)[O-]
c. COc1cc(/C=C(\C#N)C(=O)NCC2CCCO2)ccc1OCC(N)=O
d. CCCOc1ccc(/C(O)=C2/C(=O)C(=O)N(CCCn3ccnc3)C2c2cccnc2)cc1
e. CCC(C)(C)C1CCc2[nH]nc(C(=O)NCCNC(=O)OC(C)(C)C)c2C1
Answer: d. CCCOc1ccc(/C(O)=C2/C(=O)C(=O)N(CCCn3ccnc3)C2c2cccnc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCOc1ccc(/C(O)=C2/C(=O)C(=O)N(CCCn3ccnc3)C2c2cccnc2)cc1
CCCOc1ccc(/C(O)=C2/C(=O)C(=O)N(CCCn3ccnc3)C2c2cccnc2)cc1
(4Z)-4-[hydroxy-(4-propoxyphenyl)methylidene]-1-(3-imidazol-1-ylpropyl)-5-pyridin-3-ylpyrrolidine-2,3-dione