Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 12.338\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1ccccc1N1CCN(C(=S)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)CC1
b.) Cc1ccc2c(c1C)NC(=O)C2(O)CC(=O)c1ccc2c(c1)OCO2
c.) c1ccc(-c2nnc(CN3CCN(c4ccccc4)CC3)o2)cc1
d.) COc1ccc(-c2csc3ncnc(N4CCN(S(=O)(=O)c5cccc(Br)c5)CC4)c23)cc1
e.) COC(=O)C1=C(c2ccc(C(C)=O)cc2)C[C@@H]2CC[C@H]1N2C(=O)NCCNC(C)=O
Answer: a. COc1ccccc1N1CCN(C(=S)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CCN(C(=S)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)CC1
COc1ccccc1N1CCN(C(=S)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)CC1
4-(2-methoxyphenyl)-N-(4-morpholin-4-ylsulfonylphenyl)piperazine-1-carbothioamide