Problem statement: Answer the multiple-choice question.
Question: Which compound has a 15.215\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] COc1ccc(C(=O)C2CCCN(CCO)C2)c(C)c1
[b] COc1ccccc1/C=N/NC(=O)Cn1cnc([N+](=O)[O-])n1
[c] CSc1nc(C)c(CCO)c(=O)[nH]1
[d] O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1
Answer: d. O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1
O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1
N-[3-[4-(3-fluorophenyl)sulfonylpiperazin-1-yl]-3-oxopropyl]-4-(trifluoromethoxy)benzenesulfonamide