Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -13.746\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. COc1ccc(CN(C(=O)CN2C(=O)NC3(CCC(C)CC3)C2=O)C(C)Cc2cccs2)cc1
b. COc1ccc(Cn2nnnc2C(C(C)C)N2CCc3ccccc32)cc1
c. COc1ccccc1NS(=O)(=O)c1ccc(C(=O)NCC2(N(C)C)CCCCC2)cc1
d. Cc1cc(C)c(NC(=O)C2CC(=O)N(C(C)C)C2)c(C)c1
Answer: a. COc1ccc(CN(C(=O)CN2C(=O)NC3(CCC(C)CC3)C2=O)C(C)Cc2cccs2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CN(C(=O)CN2C(=O)NC3(CCC(C)CC3)C2=O)C(C)Cc2cccs2)cc1
COc1ccc(CN(C(=O)CN2C(=O)NC3(CCC(C)CC3)C2=O)C(C)Cc2cccs2)cc1
N-[(4-methoxyphenyl)methyl]-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)-N-(1-thiophen-2-ylpropan-2-yl)acetamide