Problem statement: Answer the multiple choice question.
Question: Which compound exhibits a 8.060\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(CNC(=O)C(=O)NC2CC(C)(C)NC(C)(C)C2)cc1
b) O=C(Cn1nc(-c2ccc3c(c2)OCCO3)ccc1=O)Nc1cccc(NC(=O)c2ccccn2)c1
c) CCOC(=O)c1nnn(-c2nonc2N)c1CNc1ccccc1
d) CCn1c(=O)c2c3c(sc2n(C)c1=O)CCC3
e) O=c1c2ccccc2cnn1-c1ccc(Cl)cc1
Answer: b. O=C(Cn1nc(-c2ccc3c(c2)OCCO3)ccc1=O)Nc1cccc(NC(=O)c2ccccn2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Cn1nc(-c2ccc3c(c2)OCCO3)ccc1=O)Nc1cccc(NC(=O)c2ccccn2)c1
O=C(Cn1nc(-c2ccc3c(c2)OCCO3)ccc1=O)Nc1cccc(NC(=O)c2ccccn2)c1
N-[3-[[2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-6-oxopyridazin-1-yl]acetyl]amino]phenyl]pyridine-2-carboxamide