Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 16.580\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a COC(=O)COc1ccc(S(=O)(=O)Nc2ccc(C(N)=O)cc2)cc1C
b COc1ccc(CCNC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCOCC4)cc32)cc1OC
c Cn1c(=O)c(Oc2cc(Cl)cc(Cl)c2)nc2ccccc21
d Cn1c(NCCCO)nc2c(c1=O)C1(CCCCC1)Cc1ccccc1-2
Answer: b. COc1ccc(CCNC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCOCC4)cc32)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CCNC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCOCC4)cc32)cc1OC
COc1ccc(CCNC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCOCC4)cc32)cc1OC
N-[2-(4,5-dimethoxyphenyl)ethyl]-2-(6-morpholin-4-ylsulfonyl-3-oxo-1,4-benzothiazin-4-yl)acetamide