Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 8.140\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) NC(=S)c1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12
(b) COc1ccc(C(=O)CCN2CCCC(C)C2)cc1.Cl
(c) CCn1c(COc2ccccc2OC)nnc1SCC(=O)NC1CCCC1
(d) CCOc1ccc(N(C)C(=O)CCc2nnc3ccc(N4CCCC4)nn23)cc1
(e) CCOC(=O)c1c(-c2ccc(OC)cc2)csc1NC(=O)CNCc1ccco1
Answer: e. CCOC(=O)c1c(-c2ccc(OC)cc2)csc1NC(=O)CNCc1ccco1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1c(-c2ccc(OC)cc2)csc1NC(=O)CNCc1ccco1
CCOC(=O)c1c(-c2ccc(OC)cc2)csc1NC(=O)CNCc1ccco1
ethyl 2-[[2-(furan-2-ylmethylamino)acetyl]amino]-4-(4-methoxyphenyl)thiophene-3-carboxylate