Problem statement: Answer the multiple-choice question.
Question: Which drug has a -17.654\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) COc1cc(SC)ccc1C(=O)N1CCN(S(=O)(=O)/C=C/c2ccccc2)CC1
b) CCNc1c(NC(=O)COc2ccc(Cl)cc2)c(=O)oc2ccccc12
c) O=C(CN1C(=O)NC2(CCCC2)C1=O)Nc1ccccc1
d) CCCCn1cnc2c(oc3ccccc32)c1=O
Answer: a. COc1cc(SC)ccc1C(=O)N1CCN(S(=O)(=O)/C=C/c2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(SC)ccc1C(=O)N1CCN(S(=O)(=O)/C=C/c2ccccc2)CC1
COc1cc(SC)ccc1C(=O)N1CCN(S(=O)(=O)/C=C/c2ccccc2)CC1
(2-methoxy-4-methylsulfanylphenyl)-[4-[(E)-2-phenylethenyl]sulfonylpiperazin-1-yl]methanone