Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 10.348\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCC(C)(C)n1nnnc1C(c1cccnc1)N1CCN(c2cccc(C(F)(F)F)c2)CC1
b) COC(=O)c1ccc(NC(=O)CSc2nnc(C)n2CC2CCCO2)cc1
c) COC(=O)c1ccc(C2C(C(C)=O)=C(C)Nc3ncnn32)cc1
d) Cc1cc(Cl)nc(-n2nc(C)cc2C)n1
e) O=C(Nc1ccc(Cl)c(Cl)c1)c1ccncc1
Answer: c. COC(=O)c1ccc(C2C(C(C)=O)=C(C)Nc3ncnn32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(C2C(C(C)=O)=C(C)Nc3ncnn32)cc1
COC(=O)c1ccc(C2C(C(C)=O)=C(C)Nc3ncnn32)cc1
methyl 4-(6-acetyl-5-methyl-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)benzoate