Task: Answer the multiple choice question.
Question: Which drug has a 11.258\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1ccc(S(=O)(=O)N2CCN(C(=O)CSc3n[nH]c(N)n3)CC2)c(C)c1
b) C=C(C)C(=O)N1CC2(CC(c3cccc(NC(=O)CC(c4ccccc4)c4ccccc4)c3)=NO2)C[C@H]1C(N)=O
c) O=C(COC(=O)c1ccccc1N1C(=O)C2C3CCC(C3)C2C1=O)c1ccccc1
d) CCc1ccccc1NC(=S)N(CCN(C)C)Cc1cccs1
e) COc1ccc(OC)c(-c2csc(NC(=O)C3=COCCO3)n2)c1
Answer: b. C=C(C)C(=O)N1CC2(CC(c3cccc(NC(=O)CC(c4ccccc4)c4ccccc4)c3)=NO2)C[C@H]1C(N)=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C=C(C)C(=O)N1CC2(CC(c3cccc(NC(=O)CC(c4ccccc4)c4ccccc4)c3)=NO2)C[C@H]1C(N)=O
C=C(C)C(=O)N1CC2(CC(c3cccc(NC(=O)CC(c4ccccc4)c4ccccc4)c3)=NO2)C[C@H]1C(N)=O
(8S)-3-[3-(3,3-diphenylpropanoylamino)phenyl]-7-(2-methylprop-2-enoyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide