Task: Answer the multiple choice question.
Query: Which drug has a 9.259\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] COC(=O)c1ccc(CN2CCC(Oc3cccc(C(=O)N4CCOCC4)c3)CC2)cc1
[b] O=C(NCCn1c(C(F)(F)F)nc2ccccc21)[C@H]1CCCN1c1nc(CN2CCCCC2)cs1
[c] COc1ccc(CCN2CC(C(=O)NCCc3ccccc3C(F)(F)F)CCC2=O)cc1
[d] COc1ccccc1N=NC1=C(O)CC(C)(C)CC1=O
Answer: b. O=C(NCCn1c(C(F)(F)F)nc2ccccc21)[C@H]1CCCN1c1nc(CN2CCCCC2)cs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCCn1c(C(F)(F)F)nc2ccccc21)[C@H]1CCCN1c1nc(CN2CCCCC2)cs1
O=C(NCCn1c(C(F)(F)F)nc2ccccc21)[C@H]1CCCN1c1nc(CN2CCCCC2)cs1
(2R)-1-[4-(piperidin-1-ylmethyl)-1,3-thiazol-2-yl]-N-[2-[2-(trifluoromethyl)benzimidazol-1-yl]ethyl]pyrrolidine-2-carboxamide