Problem statement: Answer the MCQ question.
Query: Which compound has a -49.505\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C1N(Cc2cccc(Cl)c2)C[C@@H]2C[C@@H](c3c[nH]c4ccccc34)N3CCC[C@@]123
b. O=C(Cn1cnc2c(nnn2Cc2ccc(F)cc2)c1=O)NCc1ccc(F)cc1
c. COc1ccc(S(=O)(=O)N2CCN(CCC(=O)Nc3ccccc3F)CC2)cc1
d. Nc1ccc(-c2nnn(Cc3ccccc3F)n2)cc1
e. CCOc1ccc(S(=O)(=O)N(CC)CC(=O)NCc2ccncc2)cc1C
Answer: a. O=C1N(Cc2cccc(Cl)c2)C[C@@H]2C[C@@H](c3c[nH]c4ccccc34)N3CCC[C@@]123
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1N(Cc2cccc(Cl)c2)C[C@@H]2C[C@@H](c3c[nH]c4ccccc34)N3CCC[C@@]123
O=C1N(Cc2cccc(Cl)c2)C[C@@H]2C[C@@H](c3c[nH]c4ccccc34)N3CCC[C@@]123
(1S,5S,7S)-3-[(3-chlorophenyl)methyl]-7-(1H-indol-3-yl)-3,8-diazatricyclo[6.3.0.01,5]undecan-2-one