Problem statement: Answer the multiple-choice question.
Question: Which compound has a -6.473\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COC(=O)Nc1nn(-c2ccc(Cl)cc2)c(=O)c(C#N)c1C
b CCOC(=O)c1snc2c(=O)[nH]cnc12
c Cc1ccc(S(=O)(=O)CCC(=O)OC(C)C(=O)Nc2ccc(N3CCOCC3)cc2)cc1
d O=C(Nc1ccc(NC(=O)c2cc3ccccc3o2)cc1)c1ccco1
e COc1ccc(-c2[nH]ncc2CN2CCCC(C(=O)c3ccc(OC)cc3OC)C2)cc1
Answer: a. COC(=O)Nc1nn(-c2ccc(Cl)cc2)c(=O)c(C#N)c1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)Nc1nn(-c2ccc(Cl)cc2)c(=O)c(C#N)c1C
COC(=O)Nc1nn(-c2ccc(Cl)cc2)c(=O)c(C#N)c1C
methyl N-[1-(4-chlorophenyl)-5-cyano-4-methyl-6-oxopyridazin-3-yl]carbamate