Problem statement: Answer the MCQ question.
Question: Which drug has a 10.826\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cc1ccc2sc3ccc(NC(=O)c4ccccc4Cl)cc3c(=O)c2c1
[b] Cc1sc2ncn(CC(=O)N3CCCCC3)c(=O)c2c1S(=O)(=O)N1CCC(C)CC1
[c] Cc1ccc(NC(=O)COc2ccc(/C=C3/NC(=O)NC3=O)cc2)cc1
[d] CCc1ccc(NC(=S)NC2CC3CCCC(C2)N3Cc2cccs2)cc1
[e] COc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)N4CCCC(C)C4)cc3nc2s1
Answer: b. Cc1sc2ncn(CC(=O)N3CCCCC3)c(=O)c2c1S(=O)(=O)N1CCC(C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1sc2ncn(CC(=O)N3CCCCC3)c(=O)c2c1S(=O)(=O)N1CCC(C)CC1
Cc1sc2ncn(CC(=O)N3CCCCC3)c(=O)c2c1S(=O)(=O)N1CCC(C)CC1
6-methyl-5-(4-methylpiperidin-1-yl)sulfonyl-3-(2-oxo-2-piperidin-1-ylethyl)thieno[2,3-d]pyrimidin-4-one