Task: Answer the multiple-choice question.
Query: Which drug has a 15.174\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1ccc(Nc2ncnc(N)n2)cc1
b) CCOc1ccc2oc(C(=O)OCC(=O)NC3CCCC3)c(C)c2c1
c) COc1cc2c(cc1OC)C(CSc1ccccc1C(=O)O)=NC(C)(C)C2
d) CCOC(=O)C1(Cc2ccccc2Cl)CCN(S(C)(=O)=O)CC1
e) CCNC(=S)NCc1ccc(F)cc1
Answer: c. COc1cc2c(cc1OC)C(CSc1ccccc1C(=O)O)=NC(C)(C)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(CSc1ccccc1C(=O)O)=NC(C)(C)C2
COc1cc2c(cc1OC)C(CSc1ccccc1C(=O)O)=NC(C)(C)C2
2-[(6,7-dimethoxy-3,3-dimethyl-4H-isoquinolin-1-yl)methylsulfanyl]benzoic acid