Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -41.947\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CN(C)CCCN=C(NO)c1ccc(Cl)cc1Cl
b) Cc1oc(-c2cccs2)nc1CN1CC[C@@](O)(c2ccccc2)[C@H]2CCCC[C@@H]21
c) Cc1nc(NC(=O)c2ccccc2)sc1C1(C)CC(c2ccccc2F)=NO1
d) Cc1cc(C)c(-n2c(SCCS(=O)(=O)c3ccc(F)cc3)n[nH]c2=O)c(C)c1
e) O=C(c1cnn(-c2ccc(Cl)cc2)c1)c1ccccc1O
Answer: e. O=C(c1cnn(-c2ccc(Cl)cc2)c1)c1ccccc1O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1cnn(-c2ccc(Cl)cc2)c1)c1ccccc1O
O=C(c1cnn(-c2ccc(Cl)cc2)c1)c1ccccc1O
[1-(4-chlorophenyl)pyrazol-4-yl]-(2-hydroxyphenyl)methanone