Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -0.279\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccc(C2=NS(=O)(=O)N(C)C(C(=O)N3CCCCC3C)=C2)cc1
b: CCCCNc1ccccc1C(=O)OCC(=O)Nc1ccc(S(N)(=O)=O)cc1
c: CSc1cc(N2CCOCC2)nc(-c2ccccc2Cl)n1
d: CCC1CN(C)C2Cc3c([nH]c4ccccc34)C(=O)CC1C2C(=O)OC
e: COc1cccc(C=O)c1OCCN1C(=O)c2ccccc2C1=O
Answer: a. COc1ccc(C2=NS(=O)(=O)N(C)C(C(=O)N3CCCCC3C)=C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2=NS(=O)(=O)N(C)C(C(=O)N3CCCCC3C)=C2)cc1
COc1ccc(C2=NS(=O)(=O)N(C)C(C(=O)N3CCCCC3C)=C2)cc1
[5-(4-methoxyphenyl)-2-methyl-1,1-dioxo-1,2,6-thiadiazin-3-yl]-(2-methylpiperidin-1-yl)methanone