Task: Answer the MCQ question.
Question: Which compound exhibits a -1.167\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Br.COc1ccc(Nc2nc(-c3sc(C)nc3C)cs2)cc1
b) C[C@H]1CN=C(N(C)C)N1CC1CCCC1
c) CCc1nnc(NC(=O)CSc2ncc(-c3ccccc3)[nH]2)s1
d) COc1cc2c(cc1OC)C(C1C(=O)CC(C)(C)CC1=O)N(C(=O)CCl)CC2
e) CCN1C(=O)N[C@H](c2ccc(Br)cc2)C(C(=O)OC)=C1C
Answer: d. COc1cc2c(cc1OC)C(C1C(=O)CC(C)(C)CC1=O)N(C(=O)CCl)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(C1C(=O)CC(C)(C)CC1=O)N(C(=O)CCl)CC2
COc1cc2c(cc1OC)C(C1C(=O)CC(C)(C)CC1=O)N(C(=O)CCl)CC2
2-[2-(2-chloroacetyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-1-yl]-5,5-dimethylcyclohexane-1,3-dione