Problem statement: Answer the MCQ question.
Query: Which drug has a -1.669\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(NCc1ccccc1Cl)c1ccc(Cn2cc(C(F)(F)F)ccc2=O)cc1
b.) CCN(CC(=O)N1CCN(Cc2ccccc2)CC1)S(=O)(=O)c1ccc(F)cc1
c.) O=C(O)CC1S/C(=N\N=C/c2ccccc2O)N(c2ccc(O)cc2)C1=O
d.) O=C(c1cc(-c2ccccc2Cl)on1)N1CCN(C(=O)c2ccco2)CC1
e.) Fc1ccc(C2CCCN2Cc2nc(Cc3ccccc3)no2)cc1
Answer: d. O=C(c1cc(-c2ccccc2Cl)on1)N1CCN(C(=O)c2ccco2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1cc(-c2ccccc2Cl)on1)N1CCN(C(=O)c2ccco2)CC1
O=C(c1cc(-c2ccccc2Cl)on1)N1CCN(C(=O)c2ccco2)CC1
[4-[5-(2-chlorophenyl)-1,2-oxazole-3-carbonyl]piperazin-1-yl]-(furan-2-yl)methanone