Problem statement: Answer the MCQ question.
Query: Which drug has a -14.172\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a. CCOC(=O)c1nnn(-c2nonc2N)c1CSc1ccc(C)cc1
b. CCOC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C1c1cc(CSc2nnnn2C)cs1
c. COc1cc(C)nc(NC(=S)N(C)C(=O)c2ccccc2)n1
Answer: b. CCOC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C1c1cc(CSc2nnnn2C)cs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C1c1cc(CSc2nnnn2C)cs1
CCOC(=O)C1=C(N)OC2=C(C(=O)CC(C)(C)C2)C1c1cc(CSc2nnnn2C)cs1
ethyl 2-amino-7,7-dimethyl-4-[4-[(1-methyltetrazol-5-yl)sulfanylmethyl]thiophen-2-yl]-5-oxo-6,8-dihydro-4H-chromene-3-carboxylate