Problem statement: Answer the multiple choice question.
Question: Which compound has a 9.701\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCN(CC)CC(=O)c1c(N)n(Cc2ccccc2)c(=O)n(C)c1=O
b.) Cc1ccc(CNC(=O)Cc2csc(Nc3nc(=S)[nH]c4ccccc34)n2)cc1
c.) NC(=O)CNC(=O)[C@@H]1CC2(CC(c3ccc(Cl)cc3)=NO2)CN1C(=O)c1ccc(Br)cc1
d.) CC(C)n1nc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc2c1=O
e.) CC(=O)Nc1ccc(N=c2cc([N+](=O)[O-])cc(Cl)n2O)cc1
Answer: c. NC(=O)CNC(=O)[C@@H]1CC2(CC(c3ccc(Cl)cc3)=NO2)CN1C(=O)c1ccc(Br)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
NC(=O)CNC(=O)[C@@H]1CC2(CC(c3ccc(Cl)cc3)=NO2)CN1C(=O)c1ccc(Br)cc1
NC(=O)CNC(=O)[C@@H]1CC2(CC(c3ccc(Cl)cc3)=NO2)CN1C(=O)c1ccc(Br)cc1
(8S)-N-(2-amino-2-oxoethyl)-7-(4-bromobenzoyl)-3-(4-chlorophenyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide