Problem statement: Answer the multiple-choice question.
Query: Which drug has a 8.193\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCC1
(b) COc1ccc(NC(=O)C(OC(=O)c2cnccn2)c2ccccc2)cc1Cl
(c) COc1ccc(C(C)=O)cc1COc1ncnc2ccccc12
(d) COC(=O)[C@@]1(Cc2ccc(OC)cc2)[C@H]2c3cc(C(=O)N4CCCC4)n(CCSCCO)c3C[C@H]2CN1C(=O)c1ccccc1
(e) COc1ccc(C(CNC(=O)c2cccc(S(=O)(=O)Nc3ccccc3Cl)c2)N2CCOCC2)cc1
Answer: e. COc1ccc(C(CNC(=O)c2cccc(S(=O)(=O)Nc3ccccc3Cl)c2)N2CCOCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(CNC(=O)c2cccc(S(=O)(=O)Nc3ccccc3Cl)c2)N2CCOCC2)cc1
COc1ccc(C(CNC(=O)c2cccc(S(=O)(=O)Nc3ccccc3Cl)c2)N2CCOCC2)cc1
3-[(2-chlorophenyl)sulfamoyl]-N-[2-(4-methoxyphenyl)-2-morpholin-4-ylethyl]benzamide