Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 19.800\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) COc1ccc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)cc1Cl
(b) NC(=S)N/N=C/c1cccc(/C=N/NC(N)=S)c1
(c) COc1ccc2c(c1)OC[C@H]1[C@@H]2N2C(=O)CNC(=O)[C@@]2(C)[C@H]1c1ccccc1
(d) Cc1ccc(NC(=S)NCc2ccc(S(N)(=O)=O)cc2)cc1Cl
Answer: c. COc1ccc2c(c1)OC[C@H]1[C@@H]2N2C(=O)CNC(=O)[C@@]2(C)[C@H]1c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2c(c1)OC[C@H]1[C@@H]2N2C(=O)CNC(=O)[C@@]2(C)[C@H]1c1ccccc1
COc1ccc2c(c1)OC[C@H]1[C@@H]2N2C(=O)CNC(=O)[C@@]2(C)[C@H]1c1ccccc1
(1S,10R,11R,12R)-5-methoxy-12-methyl-11-phenyl-8-oxa-14,17-diazatetracyclo[8.7.0.02,7.012,17]heptadeca-2(7),3,5-triene-13,16-dione