Problem statement: Answer the MCQ question.
Query: Which compound has a -7.278\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1cccc(CNC(=O)c2ccccc2C(=O)NC(C)(C)C(=O)NCc2cccc(OC)c2)c1
b) COc1ccc(F)cc1S(=O)(=O)n1nc(C)cc1C
c) Cc1nc(-c2ccc(S(=O)(=O)Oc3ccc(Cl)cc3Cl)s2)cs1
d) C=CCN(c1ccccc1Cl)S(=O)(=O)c1cccc(C(=O)NCCc2ccc(OC)cc2)c1
e) Cc1cc(NC(=O)C2CCCN(S(=O)(=O)c3c(C)noc3C)C2)n[nH]1
Answer: e. Cc1cc(NC(=O)C2CCCN(S(=O)(=O)c3c(C)noc3C)C2)n[nH]1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cc(NC(=O)C2CCCN(S(=O)(=O)c3c(C)noc3C)C2)n[nH]1
Cc1cc(NC(=O)C2CCCN(S(=O)(=O)c3c(C)noc3C)C2)n[nH]1
1-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]-N-(5-methyl-1H-pyrazol-3-yl)piperidine-3-carboxamide