Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a 0.481\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CN1CCN(c2ccc(S(=O)(=O)N3CCCCC3)cc2NC(=O)CSCc2ccccc2)CC1
(b) O=C(CC(NS(=O)(=O)c1ccc(Cl)cc1)c1ccco1)N1CCc2ccccc21
(c) CCOc1ccccc1NC=C1C(=O)OC(C)(C)OC1=O
(d) NC(=S)Nn1c(CCC(=O)O)ccc1-c1ccc(Br)cc1
(e) COc1cccc(CNC(=O)Cn2ccc3cc(S(=O)(=O)N4CCCCCC4)ccc32)c1OC
Answer: b. O=C(CC(NS(=O)(=O)c1ccc(Cl)cc1)c1ccco1)N1CCc2ccccc21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CC(NS(=O)(=O)c1ccc(Cl)cc1)c1ccco1)N1CCc2ccccc21
O=C(CC(NS(=O)(=O)c1ccc(Cl)cc1)c1ccco1)N1CCc2ccccc21
4-chloro-N-[3-(2,3-dihydroindol-1-yl)-1-(furan-2-yl)-3-oxopropyl]benzenesulfonamide