Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a -5.519\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COCCn1c(SCC(=O)N2CCCCCC2)nc2c(c1=O)SCC2
(b) O=C(Cc1ccc(S(=O)(=O)N2CCOCC2)s1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
(c) O=C(C[n+]1ccn(CCCNP2(=O)C=C(c3ccccc3)OC(c3ccccc3)=C2)c1)c1ccccc1.[Br-]
(d) O=C(NCc1cccnc1)c1cccc(S(=O)(=O)Nc2cccc(Cl)c2)c1
(e) COc1cccc(NC(=O)C2CCC2)c1
Answer: b. O=C(Cc1ccc(S(=O)(=O)N2CCOCC2)s1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Cc1ccc(S(=O)(=O)N2CCOCC2)s1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
O=C(Cc1ccc(S(=O)(=O)N2CCOCC2)s1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
1-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]-2-(5-morpholin-4-ylsulfonylthiophen-2-yl)ethanone