Problem statement: Answer the multiple-choice question.
Question: Which compound has a 22.508\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C(CCSc1ccccc1)Nc1ccccc1Br
(b) COc1ccc(C(=O)C[n+]2cc(Br)cc3ccccc32)cc1[N+](=O)[O-].[Br-]
(c) COc1ccc(CNC(=O)C2(C)Cc3ccccc3C(=O)O2)cc1
(d) NS(=O)(=O)c1ccc(CCNc2nc(C(F)(F)F)nc3ccccc23)cc1
(e) O=C(CSc1ccccc1)NCC1(N2CCOCC2)CCCCC1
Answer: c. COc1ccc(CNC(=O)C2(C)Cc3ccccc3C(=O)O2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C2(C)Cc3ccccc3C(=O)O2)cc1
COc1ccc(CNC(=O)C2(C)Cc3ccccc3C(=O)O2)cc1
N-[(4-methoxyphenyl)methyl]-3-methyl-1-oxo-4H-isochromene-3-carboxamide