Problem statement: Answer the MCQ question.
Query: Which drug has a -77.083\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCOC(=O)c1sc(/N=C/C2=C(O)CC(C)(C)CC2=O)c(C(=O)OCC)c1C
(b) OCCN(CC(O)COc1ccccc1)CC(O)Cn1ccc2ccccc21
(c) CCN(CC)c1ccc(/C=C2\SC(N)=NC2=O)cc1
(d) O=C1NC(=S)NC(=O)C1C1CCCCC1
(e) CCOc1ccc(CN2CCN(C/C=C/c3ccc(OC)cc3)CC2CCO)cc1
Answer: e. CCOc1ccc(CN2CCN(C/C=C/c3ccc(OC)cc3)CC2CCO)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(CN2CCN(C/C=C/c3ccc(OC)cc3)CC2CCO)cc1
CCOc1ccc(CN2CCN(C/C=C/c3ccc(OC)cc3)CC2CCO)cc1
2-[1-[(4-ethoxyphenyl)methyl]-4-[(E)-3-(4-methoxyphenyl)prop-2-enyl]piperazin-2-yl]ethanol