Problem statement: Answer the MCQ question.
Question: Which compound has a 7.478\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(Oc2coc3cc(O)ccc3c2=O)cc1
(b) O=C(CCc1nnc2ccc(NCc3ccco3)nn12)N1CCN(c2ccc(F)cc2)CC1
(c) COc1ccc(CCNC(=O)CN2C(=O)COc3ccc(S(=O)(=O)N4CCOCC4)cc32)cc1OC
(d) Cc1cc(C(=O)CN2C(=O)C(=O)N(C3CCCC3)C2=O)c(C)n1CCc1ccc(F)cc1
(e) O=S(=O)(Nc1cccc(F)c1)c1cccc2nsnc12
Answer: b. O=C(CCc1nnc2ccc(NCc3ccco3)nn12)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCc1nnc2ccc(NCc3ccco3)nn12)N1CCN(c2ccc(F)cc2)CC1
O=C(CCc1nnc2ccc(NCc3ccco3)nn12)N1CCN(c2ccc(F)cc2)CC1
1-[4-(4-fluorophenyl)piperazin-1-yl]-3-[6-(furan-2-ylmethylamino)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]propan-1-one