Problem statement: Answer the multiple-choice question.
Question: What is the human ether-à-go-go related gene (hERG) inhibition at 1uM of a compound with the SMILES COc1ccc(-c2csc3ncnc(N4CCN(S(=O)(=O)c5ccc(Cl)s5)CC4)c23)cc1?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) -3.608
b) -1.018
c) -0.353
d) -10.226
e) 16.109
Answer: b. -1.018\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COc1ccc(-c2csc3ncnc(N4CCN(S(=O)(=O)c5ccc(Cl)s5)CC4)c23)cc1
COc1ccc(-c2csc3ncnc(N4CCN(S(=O)(=O)c5ccc(Cl)s5)CC4)c23)cc1
4-[4-(5-chlorothiophen-2-yl)sulfonylpiperazin-1-yl]-5-(4-methoxyphenyl)thieno[2,3-d]pyrimidine