Problem statement: Answer the multiple choice question.
Question: Which drug has a 1.219\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: Cc1nc(C(F)(F)F)c(C(=O)Sc2ccc(Cl)cc2)s1
b: Cc1nc2c(-c3ccc(Cl)cc3)cnn2c2c1CCC2
c: CCN(C(=O)C1CC1)C1CCS(=O)(=O)C1
d: CCOc1ccc(CNC(=O)c2ccco2)cc1
e: CCn1ccnc1CNC(=O)C1CCC(=O)N(Cc2cccc(C(F)(F)F)c2)C1
Answer: e. CCn1ccnc1CNC(=O)C1CCC(=O)N(Cc2cccc(C(F)(F)F)c2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCn1ccnc1CNC(=O)C1CCC(=O)N(Cc2cccc(C(F)(F)F)c2)C1
CCn1ccnc1CNC(=O)C1CCC(=O)N(Cc2cccc(C(F)(F)F)c2)C1
N-[(1-ethylimidazol-2-yl)methyl]-6-oxo-1-[[3-(trifluoromethyl)phenyl]methyl]piperidine-3-carboxamide