Task: Answer the multiple-choice question.
Question: Which drug has a 7.556\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COC(=O)c1ccc2c(=O)n(CCN3CCOCC3)c(=S)[nH]c2c1
b.) COC(=O)C1=C(c2ccc(F)cc2F)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(F)cc1
c.) O=C(c1ccccc1Cl)N1CCC(c2nc3c(nnn3Cc3ccco3)c(=O)[nH]2)CC1
d.) CN(C(=O)COC(=O)c1cc(S(=O)(=O)N(C)C)ccc1Cl)C1CCS(=O)(=O)C1
e.) Nc1nnc(SCc2ccc(F)cc2Cl)s1
Answer: b. COC(=O)C1=C(c2ccc(F)cc2F)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(F)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(F)cc2F)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(F)cc1
COC(=O)C1=C(c2ccc(F)cc2F)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(F)cc1
methyl (1R,5S)-3-(2,4-difluorophenyl)-8-[(4-fluorophenyl)methylcarbamoyl]-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate