Problem statement: Answer the MCQ question.
Question: Which drug has a -0.310\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) O=S(=O)(c1ccc(Cl)cc1)N1CCC(c2nc3ccccc3[nH]2)CC1
b) CC(C)(C)NC(=O)C(c1ccc(OCC(N)=O)cc1)N(C(=O)c1cccnc1)C1CC1
c) CC1(C)CC(=O)C2=C(C1)N(CC1CCCO1)C(=O)C2(O)C(F)(F)F
d) CCc1ccc(-c2nc(CSCC(=O)N3CCN(c4ncccn4)CC3)c(C)o2)cc1
Answer: b. CC(C)(C)NC(=O)C(c1ccc(OCC(N)=O)cc1)N(C(=O)c1cccnc1)C1CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)(C)NC(=O)C(c1ccc(OCC(N)=O)cc1)N(C(=O)c1cccnc1)C1CC1
CC(C)(C)NC(=O)C(c1ccc(OCC(N)=O)cc1)N(C(=O)c1cccnc1)C1CC1
N-[1-[4-(2-amino-2-oxoethoxy)phenyl]-2-(tert-butylamino)-2-oxoethyl]-N-cyclopropylpyridine-3-carboxamide