Problem statement: Answer the multiple-choice question.
Query: Which drug has a 12.801\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) COc1ccc(-c2csc(NC(=O)CN3C(=O)CCC3=O)n2)c(OC)c1
b) COC(=O)C1C(=O)C2=C(CC1C)Nc1ccccc1NC2c1ccc(C)s1
c) CCCc1cc(=O)n2[nH]c(NCc3cccs3)nc2n1
d) COc1ccc(C2CC(Cn3cc(C#N)c(=O)n(C)c3=O)ON2C)cc1
Answer: b. COC(=O)C1C(=O)C2=C(CC1C)Nc1ccccc1NC2c1ccc(C)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1C(=O)C2=C(CC1C)Nc1ccccc1NC2c1ccc(C)s1
COC(=O)C1C(=O)C2=C(CC1C)Nc1ccccc1NC2c1ccc(C)s1
methyl 9-methyl-6-(5-methylthiophen-2-yl)-7-oxo-5,6,8,9,10,11-hexahydrobenzo[b][1,4]benzodiazepine-8-carboxylate