Problem statement: Answer the MCQ question.
Question: Which drug has a -22.743\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COC(=O)c1c(C)[nH]c(C(=O)COc2ccc3ccc(=O)oc3c2)c1C
b) O=C(c1ccccc1F)N(NC(=O)C(O)(c1ccccc1)c1ccccc1)c1ccccc1
c) COc1ccc(OC)c(NC(=O)C2CCN(S(=O)(=O)c3ccc4c(c3)CC(C)N4C(C)=O)CC2)c1
d) O=C(NCc1ccccn1)c1ccccc1OCc1ccc(F)cc1
e) N#CCCn1cc(/C=N/NC(N)=S)c(-c2ccc(-c3ccccc3)cc2)n1
Answer: d. O=C(NCc1ccccn1)c1ccccc1OCc1ccc(F)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCc1ccccn1)c1ccccc1OCc1ccc(F)cc1
O=C(NCc1ccccn1)c1ccccc1OCc1ccc(F)cc1
2-[(4-fluorophenyl)methoxy]-N-(pyridin-2-ylmethyl)benzamide