Task: Answer the MCQ question.
Question: Which compound exhibits a 12.816\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C(NCCNC1CCC(c2ccccc2)CC1)c1ccc(F)cc1
b) CCN(CC(=O)Nc1c(F)cccc1F)C(=O)c1ccc2c(c1)NC(=O)C(C)S2
c) O=C(NCCCN1CCN(c2ccc(F)cc2)CC1)NC12CC3CC(CC(C3)C1)C2
d) COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1Cc2ccccc2C1
e) CCCCn1c(N)c(N(CC(C)C)C(=O)Cc2ccc3c(c2)OCCO3)c(=O)[nH]c1=O
Answer: d. COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1Cc2ccccc2C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1Cc2ccccc2C1
COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)NC1Cc2ccccc2C1
methyl (1R,5S)-8-(2,3-dihydro-1H-inden-2-ylcarbamoyl)-3-(3-fluoro-4-phenylphenyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate