Problem statement: Answer the MCQ question.
Query: Which compound has a 16.602\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1cccc(-c2nnc(-c3ccccc3)o2)c1
b. COC(=O)c1ccccc1C(=O)N1CCCC(CNC(=O)c2ccc(F)cc2)C1
c. CCn1c(N2CCN(CC(=O)c3c(C)n(C)c4ccccc34)CC2)nc2c1c(=O)[nH]c(=O)n2C
d. COc1ccc(NC(=O)C2CCCC2)cn1
e. O=C(Nc1ccc2c(c1)OCO2)C1CCN(Cc2cc3c(cc2O)OCO3)CC1
Answer: b. COC(=O)c1ccccc1C(=O)N1CCCC(CNC(=O)c2ccc(F)cc2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccccc1C(=O)N1CCCC(CNC(=O)c2ccc(F)cc2)C1
COC(=O)c1ccccc1C(=O)N1CCCC(CNC(=O)c2ccc(F)cc2)C1
methyl 2-[3-[[(4-fluorobenzoyl)amino]methyl]piperidine-1-carbonyl]benzoate