Problem statement: Answer the multiple choice question.
Query: Which compound has a 6.418\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1cc(O)c(-c2cc(C(=O)Nc3ccc(S(=O)(=O)N4CCOCC4)cc3)[nH]n2)cc1C
(b) O=C(Cc1csc(Nc2nc(=S)[nH]c3ccccc23)n1)NCCCN1CCN(c2cccc(Cl)c2)CC1
(c) CCOc1ccc(OCCC(=O)OCC(=O)Nc2ccc(C)c(S(=O)(=O)N3CCCCC3)c2)cc1
(d) COCCNC(=O)c1nn2cccnc2c1Cl
(e) COC(=O)c1ccc(CNC(=O)C(NC(=O)c2ccco2)C(C)C)cc1
Answer: e. COC(=O)c1ccc(CNC(=O)C(NC(=O)c2ccco2)C(C)C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(CNC(=O)C(NC(=O)c2ccco2)C(C)C)cc1
COC(=O)c1ccc(CNC(=O)C(NC(=O)c2ccco2)C(C)C)cc1
methyl4-[[[2-(furan-2-carbonylamino)-3-methylbutanoyl]amino]methyl]benzoate