Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -8.709\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C(CSc1nnc(Nc2ccccc2)s1)NCCN1C(=O)CSC1=O
(b) COc1ccc(NS(=O)(=O)c2cccc(C(=O)NCCCn3ccnc3)c2)cc1
(c) C=CCNC(=O)[C@@H]1CSC2c3ccc(OC)c(OC)c3C(=O)N21
(d) O=C(c1ccco1)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1
(e) COc1ccc(C(=O)/C=C(\C)NCc2ccc3c(c2)OCO3)cc1
Answer: e. COc1ccc(C(=O)/C=C(\C)NCc2ccc3c(c2)OCO3)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)/C=C(\C)NCc2ccc3c(c2)OCO3)cc1
COc1ccc(C(=O)/C=C(\C)NCc2ccc3c(c2)OCO3)cc1
(E)-3-(1,3-benzodioxol-5-ylmethylamino)-1-(4-methoxyphenyl)but-2-en-1-one