Problem statement: Answer the MCQ question.
Question: Which compound has a -1.827\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] Cc1ccc(CNC(=O)CS(=O)(=O)c2ccccc2)cc1
[b] COc1ccc(C(=O)N/C(=C/c2cccnc2)C(=O)N2CCCCCC2)cc1OC
[c] Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CC(=O)N(c4ccc5c(c4)OCCO5)C3)CC2)cc1
[d] O=C1CCN(Cc2ccc(O)cc2)CCN1[C@H](CO)Cc1ccccc1
[e] Cc1ccc(OCc2cc(C(=O)NC(C)Cc3cccc(C)n3)no2)cn1
Answer: c. Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CC(=O)N(c4ccc5c(c4)OCCO5)C3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CC(=O)N(c4ccc5c(c4)OCCO5)C3)CC2)cc1
Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CC(=O)N(c4ccc5c(c4)OCCO5)C3)CC2)cc1
1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-[4-(4-methylphenyl)sulfonylpiperazine-1-carbonyl]pyrrolidin-2-one