Problem statement: Answer the MCQ question.
Question: Which drug has a 22.621\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1ccc(-n2nc(C(=O)NCC(=O)Nc3cc(OC)ccc3OC)c3ccccc3c2=O)cc1
b O=C(NNS(=O)(=O)c1ccc(C(F)(F)F)cc1)c1cnn(-c2ccccc2)c1C(F)(F)F
c CC1CCC(NC(=O)c2ccc3snnc3c2)CC1
d CCC1=NN2C(=N)/C(=C\c3ccc(OCCOc4ccc(NC(C)=O)cc4)c(OC)c3)C(=O)N=C2S1
e CCOP(=O)(/C=C(\Cl)c1ccccc1)C(O)c1ccc(F)cc1
Answer: d. CCC1=NN2C(=N)/C(=C\c3ccc(OCCOc4ccc(NC(C)=O)cc4)c(OC)c3)C(=O)N=C2S1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC1=NN2C(=N)/C(=C\c3ccc(OCCOc4ccc(NC(C)=O)cc4)c(OC)c3)C(=O)N=C2S1
CCC1=NN2C(=N)/C(=C\c3ccc(OCCOc4ccc(NC(C)=O)cc4)c(OC)c3)C(=O)N=C2S1
N-[4-[2-[4-[(E)-(2-ethyl-5-imino-7-oxo-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-ylidene)methyl]-2-methoxyphenoxy]ethoxy]phenyl]acetamide