Problem statement: Answer the multiple-choice question.
Question: Which compound has a -0.769\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) Cc1ccc(-n2c(=O)/c(=C/c3ccncc3)s/c2=C(\C#N)C(=O)c2c(C)[nH]c3ccccc23)cc1
b) N#CC(C#N)=C1C=CC=CN1/C(=C\c1ccccc1)C(=O)c1cccs1
c) CCOc1ccc(-c2nnc3ccc(SCC(=O)Nc4nc5ccc(C)cc5s4)nn23)cc1
d) COC(=O)c1ccc(C(=O)NC2CC(C)(C)Cc3c2cnn3-c2ccc(F)cc2)nc1
Answer: d. COC(=O)c1ccc(C(=O)NC2CC(C)(C)Cc3c2cnn3-c2ccc(F)cc2)nc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(C(=O)NC2CC(C)(C)Cc3c2cnn3-c2ccc(F)cc2)nc1
COC(=O)c1ccc(C(=O)NC2CC(C)(C)Cc3c2cnn3-c2ccc(F)cc2)nc1
methyl 6-[[1-(4-fluorophenyl)-6,6-dimethyl-5,7-dihydro-4H-indazol-4-yl]carbamoyl]pyridine-3-carboxylate