Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -36.797\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] CCOC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)N3CCCC3)CC2)CC1
[b] O=C1COc2ccc(NC(=O)N3CCN(c4ccc(F)cc4)CC3)cc2N1
[c] Cc1ccc(OCCSc2cc(C)nc(N)n2)cc1
[d] COc1ccc(/C=N/Nc2ncc(C(F)(F)F)cc2Cl)cc1OC
Answer: b. O=C1COc2ccc(NC(=O)N3CCN(c4ccc(F)cc4)CC3)cc2N1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1COc2ccc(NC(=O)N3CCN(c4ccc(F)cc4)CC3)cc2N1
O=C1COc2ccc(NC(=O)N3CCN(c4ccc(F)cc4)CC3)cc2N1
4-(4-fluorophenyl)-N-(3-oxo-4H-1,4-benzoxazin-6-yl)piperazine-1-carboxamide