Task: Answer the multiple-choice question.
Question: Which drug has a -8.206\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) CCOC(=O)[C@@H]1[C@H]2COc3ccc(Br)cc3[C@H]2N2C(=O)N(c3ccc(F)cc3)C(=O)[C@@]12C
b) Cc1nc2ccccc2c(=O)n1NC(=O)c1c(O)c2c(n(CC(C)C)c1=O)CCCC2
c) CCOC(=O)c1cnc2c(OC)cccc2c1N1CCN(c2ccccn2)CC1
d) Cc1ccc2c(c1)N(S(=O)(=O)c1cc(-c3cc(C)no3)ccc1C)CCO2
Answer: c. CCOC(=O)c1cnc2c(OC)cccc2c1N1CCN(c2ccccn2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1cnc2c(OC)cccc2c1N1CCN(c2ccccn2)CC1
CCOC(=O)c1cnc2c(OC)cccc2c1N1CCN(c2ccccn2)CC1
ethyl 8-methoxy-4-(4-pyridin-2-ylpiperazin-1-yl)quinoline-3-carboxylate