Problem statement: Answer the multiple-choice question.
Question: Which compound has a -16.002\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Cc1ccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc3c(c2)CCC(=O)N3)cc1Cl
b.) Cc1c(Cl)cccc1NC(=O)CC(Cc1ccccc1)C(=O)O
c.) O=C(COC(=O)CNC(=O)c1ccc(Br)o1)Nc1ccccc1OC(F)F
d.) CC12CCC(C(=O)NC(c3ccccc3)c3ccccc3)(OC1=O)C2(C)C
e.) CCOC(=O)C(C)Oc1c(Br)cc(C2NC(=O)NC(C)=C2C(C)=O)cc1OCC
Answer: c. O=C(COC(=O)CNC(=O)c1ccc(Br)o1)Nc1ccccc1OC(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)CNC(=O)c1ccc(Br)o1)Nc1ccccc1OC(F)F
O=C(COC(=O)CNC(=O)c1ccc(Br)o1)Nc1ccccc1OC(F)F
5-bromo-N-[2-[2-[2-(difluoromethoxy)anilino]-2-oxoethoxy]-2-oxoethyl]furan-2-carboxamide