Task: Answer the MCQ question.
Query: Which drug exhibits a 10.983\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O=C(O)c1ccc(N2C(=O)CC(Cc3ccccc3)C2=O)cc1
[b] Cc1c(NC(=O)c2ccccc2NC(=O)c2ccccc2)cccc1C(=O)O
[c] COc1cccc(C2=Nn3c(nnc3-c3ccccc3O)SC2)c1
[d] COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCCCC1
[e] Cc1nn(C2CCS(=O)(=O)C2)c(C)c1CN(C)C(=O)c1cccc(Cl)c1
Answer: d. COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCCCC1
COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCCCC1
methyl (1R,5S)-3-(3,4-dimethoxyphenyl)-8-(piperidine-1-carbonyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate