Problem statement: Answer the multiple choice question.
Query: Which drug has a 13.085\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1cc(NC(=O)c2cc(C)no2)c(OC)cc1Cl
(b) CCn1c(SCC(=O)Nc2nccs2)nnc1-c1ccc(C)cc1
(c) O=C(COC(=O)CNC(=O)c1ccccc1F)NC12CC3CC(CC(C3)C1)C2
(d) COc1ccc(-c2ccc(N(C)C)cc2)cc1[C@H]1[C@@H]2C=CCC[C@@]2(C)C(=O)N1Cc1ccccc1
(e) COc1ccc(N2CCN(CCNS(=O)(=O)c3ccc(C)cc3)CC2)cc1
Answer: d. COc1ccc(-c2ccc(N(C)C)cc2)cc1[C@H]1[C@@H]2C=CCC[C@@]2(C)C(=O)N1Cc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2ccc(N(C)C)cc2)cc1[C@H]1[C@@H]2C=CCC[C@@]2(C)C(=O)N1Cc1ccccc1
COc1ccc(-c2ccc(N(C)C)cc2)cc1[C@H]1[C@@H]2C=CCC[C@@]2(C)C(=O)N1Cc1ccccc1
(3R,3aR,7aR)-2-benzyl-3-[5-[4-(dimethylamino)phenyl]-2-methoxyphenyl]-7a-methyl-3,3a,6,7-tetrahydroisoindol-1-one