Problem statement: Answer the MCQ question.
Question: Which drug has a -5.307\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a CCC(NC(=O)c1ccccc1NC(=O)c1ccco1)C(=O)NC1CCCCC1
b CCCCS(=O)CC(COc1ccc(Cl)cc1)OC(=O)c1ccccc1
c COc1ccc(C2=NS(=O)(=O)N(C)C(C(=O)NCc3ccccn3)=C2)cc1
d N#CC1=C(N)NC(=S)C(C(N)=O)C1c1ccccc1F
e CCOc1cc(CN2CCC(n3nccc3NC(=O)C3CC3)CC2)ccc1O
Answer: c. COc1ccc(C2=NS(=O)(=O)N(C)C(C(=O)NCc3ccccn3)=C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2=NS(=O)(=O)N(C)C(C(=O)NCc3ccccn3)=C2)cc1
COc1ccc(C2=NS(=O)(=O)N(C)C(C(=O)NCc3ccccn3)=C2)cc1
5-(4-methoxyphenyl)-2-methyl-1,1-dioxo-N-(pyridin-2-ylmethyl)-1,2,6-thiadiazine-3-carboxamide