Problem statement: Answer the multiple-choice question.
Question: Which drug has a 3.380\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. COc1ccccc1N1CCN(C(=O)C2CCCN(c3ncnc4c3nc3n4CCCCC3)C2)CC1
b. CNC(=O)CSc1nnc(COc2ccc(Cl)cc2)n1CCOC
c. CCn1c(=O)n(CC)c2cc(N3CCCC3)c(NC(=O)c3ccc(OC)c(Br)c3)cc21
d. O=C(C1CC1)N1CCc2cc(Br)cc(S(=O)(=O)NCCCN3CCCCC3)c21
Answer: a. COc1ccccc1N1CCN(C(=O)C2CCCN(c3ncnc4c3nc3n4CCCCC3)C2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CCN(C(=O)C2CCCN(c3ncnc4c3nc3n4CCCCC3)C2)CC1
COc1ccccc1N1CCN(C(=O)C2CCCN(c3ncnc4c3nc3n4CCCCC3)C2)CC1
[4-(2-methoxyphenyl)piperazin-1-yl]-[1-(7,8,9,10-tetrahydro-6H-purino[9,8-a]azepin-4-yl)piperidin-3-yl]methanone