Problem statement: Answer the MCQ question.
Query: Which compound exhibits a 16.117\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: N#Cc1ccc(CN2CCN(C(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)CC2)cc1
b: CCCCN1CC[C@H]2C=CC[C@@H](C(=O)Nc3nccs3)[C@H]2C1=O
c: O=S(=O)(NCC(c1cccnc1)N1CCN(c2ccccc2)CC1)c1cccs1
d: COC(=O)NNC(=O)C(c1ccccc1)c1ccccc1
e: COc1ccc(-n2c(O)c(C(C)=NC3CC3)c(=O)[nH]c2=O)cc1
Answer: b. CCCCN1CC[C@H]2C=CC[C@@H](C(=O)Nc3nccs3)[C@H]2C1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCN1CC[C@H]2C=CC[C@@H](C(=O)Nc3nccs3)[C@H]2C1=O
CCCCN1CC[C@H]2C=CC[C@@H](C(=O)Nc3nccs3)[C@H]2C1=O
(4aS,8R,8aS)-2-butyl-1-oxo-N-(1,3-thiazol-2-yl)-3,4,4a,7,8,8a-hexahydroisoquinoline-8-carboxamide