Task: Answer the multiple choice question.
Query: Which drug exhibits a -25.718\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) O=C(CCNC(=O)C1CCN(S(=O)(=O)c2ccc(F)cc2)CC1)NCc1ccc(Cl)cc1
(b) Cc1ccc(CNC(=O)C2CCCCC2C(=O)O)cc1
(c) CCCCC[C@H]1CN(CCCC)C(=O)[C@@H]1CC(=O)NCc1ccccc1
(d) Cl.O=C(O)CCCCCNc1nc(-c2ccccc2)nc2ccccc12
Answer: c. CCCCC[C@H]1CN(CCCC)C(=O)[C@@H]1CC(=O)NCc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCC[C@H]1CN(CCCC)C(=O)[C@@H]1CC(=O)NCc1ccccc1
CCCCC[C@H]1CN(CCCC)C(=O)[C@@H]1CC(=O)NCc1ccccc1
N-benzyl-2-[(3R,4R)-1-butyl-2-oxo-4-pentylpyrrolidin-3-yl]acetamide