Problem statement: Answer the multiple choice question.
Question: Which drug has a -24.201\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CC(OC(=O)CNS(=O)(=O)c1ccc(C#N)cc1)C(=O)Nc1ccc(Cl)cn1
b) COc1ccccc1/C=C1\SC(=O)N(CC(=O)NCCCn2ccnc2)C1=O
c) Cc1cc(C)n2nc(C(=O)OCC(=O)NCc3ccc(Cl)cc3)nc2n1
d) Cc1[nH]c(=S)c(C#N)c(C)c1CC(=O)c1ccc(Br)cc1
e) Nc1cc([N+](=O)[O-])ccc1Nc1ccc(O)cc1
Answer: a. CC(OC(=O)CNS(=O)(=O)c1ccc(C#N)cc1)C(=O)Nc1ccc(Cl)cn1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(OC(=O)CNS(=O)(=O)c1ccc(C#N)cc1)C(=O)Nc1ccc(Cl)cn1
CC(OC(=O)CNS(=O)(=O)c1ccc(C#N)cc1)C(=O)Nc1ccc(Cl)cn1
[1-[(5-chloropyridin-2-yl)amino]-1-oxopropan-2-yl] 2-[(4-cyanophenyl)sulfonylamino]acetate