Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -2.383\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: C=CCn1c(N)cc(=O)nc1SCC(=O)Nc1ccccc1C(N)=O
b: Cc1cc(CN2CCN(CCC#N)CC2)c(O)c(C2(C)CCCCC2)c1
c: c1cnc2c(C3NCCc4c3[nH]c3ccccc43)cccc2c1
d: COC(=O)c1cc(NC(=O)CN2CCc3cc4c(cc3C2)OCCCO4)cc(C(=O)OC)c1
e: O=C(c1ccc2c3c(cccc13)C(=O)N(c1cccc(C(F)(F)F)c1)C2=O)N1CCN(c2ccccc2)CC1
Answer: d. COC(=O)c1cc(NC(=O)CN2CCc3cc4c(cc3C2)OCCCO4)cc(C(=O)OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cc(NC(=O)CN2CCc3cc4c(cc3C2)OCCCO4)cc(C(=O)OC)c1
COC(=O)c1cc(NC(=O)CN2CCc3cc4c(cc3C2)OCCCO4)cc(C(=O)OC)c1
dimethyl 5-[[2-(2,3,4,7,9,10-hexahydro-[1,4]dioxepino[2,3-g]isoquinolin-8-yl)acetyl]amino]benzene-1,3-dicarboxylate