Problem statement: Answer the MCQ question.
Question: Which compound has a -5.547\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1cccc(C(=O)c2c(C)c(CCC#N)n3ccccc23)c1
b: CCCC(=O)NNc1c2ccccc2nc2ccccc12
c: COc1ccc(S(=O)(=O)Cc2ccc(C(=O)N3CCN(c4ncccn4)CC3)o2)cc1
d: Cc1cc(NCCNC2=CC(=O)CCC2)nc2ccccc12
e: Cc1ccccc1OCC(=O)Nc1sc2c(c1C#N)CCC2
Answer: c. COc1ccc(S(=O)(=O)Cc2ccc(C(=O)N3CCN(c4ncccn4)CC3)o2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)Cc2ccc(C(=O)N3CCN(c4ncccn4)CC3)o2)cc1
COc1ccc(S(=O)(=O)Cc2ccc(C(=O)N3CCN(c4ncccn4)CC3)o2)cc1
[5-[(4-methoxyphenyl)sulfonylmethyl]furan-2-yl]-(4-pyrimidin-2-ylpiperazin-1-yl)methanone