Problem statement: Answer the multiple choice question.
Query: Which compound has a -4.839\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: Fc1ccc(NC(=S)NC2CC3CCCC(C2)N3Cc2cccs2)cc1
b: Cc1sc2ncn(CC(=O)NCCCN3CCC(C)CC3)c(=O)c2c1S(=O)(=O)N1CCC(C)CC1
c: COc1cc2cc(-c3ccc(OC)c(OC)c3C)nc(N)c2cc1OC
d: CC(C)(C)C1CCc2[nH]nc(C(=O)O)c2C1
e: COC(C[C@H]1O[C@@H]1[C@H](O)COCc1ccccc1)OC
Answer: c. COc1cc2cc(-c3ccc(OC)c(OC)c3C)nc(N)c2cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2cc(-c3ccc(OC)c(OC)c3C)nc(N)c2cc1OC
COc1cc2cc(-c3ccc(OC)c(OC)c3C)nc(N)c2cc1OC
3-(3,4-dimethoxy-2-methylphenyl)-6,7-dimethoxyisoquinolin-1-amine