Problem statement: Answer the multiple choice question.
Query: Which drug has a -7.564\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a. COc1ccccc1CCNC(=O)C(C)n1nc(C)c2c(C)n(-c3ccccc3)nc2c1=O
b. Cc1cccc(N2CCN(C(=O)c3cccc(S(=O)(=O)N4CCc5ccccc5C4)c3)CC2C)c1
c. CC(C)C(=O)c1cn(Cc2ccccc2C#N)c2ccccc12
Answer: a. COc1ccccc1CCNC(=O)C(C)n1nc(C)c2c(C)n(-c3ccccc3)nc2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1CCNC(=O)C(C)n1nc(C)c2c(C)n(-c3ccccc3)nc2c1=O
COc1ccccc1CCNC(=O)C(C)n1nc(C)c2c(C)n(-c3ccccc3)nc2c1=O
2-(3,4-dimethyl-7-oxo-2-phenylpyrazolo[3,4-d]pyridazin-6-yl)-N-[2-(2-methoxyphenyl)ethyl]propanamide