Problem statement: Answer the multiple choice question.
Query: Which compound exhibits a -49.402\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CC(Sc1n[nH]c(=O)[nH]c1=O)C(=O)OCc1ccccc1
b. CC(=O)NC(Cc1ccccc1)C(=O)N1CCN(C(=O)c2cccs2)CC1
c. CC(C)(C)C(=O)Nc1ccc(S(=O)(=O)c2ccc(NC(=O)C(C)(C)C)cc2)cc1
d. CC(=O)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1
e. CC(CC(=O)Nc1ccc(Cl)c([N+](=O)[O-])c1)c1ccccc1
Answer: d. CC(=O)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=O)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1
CC(=O)N1CCN(c2nc(-c3cccs3)nc3ccccc23)CC1
1-[4-(2-thiophen-2-ylquinazolin-4-yl)piperazin-1-yl]ethanone