Problem statement: Answer the multiple choice question.
Question: Which drug has a 8.044\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1nnsc1C(=O)Nc1cccc(Cl)c1Cl
b. Cc1ccccc1NC(=O)c1c(C)nc(SCC(=O)OCc2ccccc2)c(C#N)c1-c1ccc(F)cc1
c. COc1cc(C(=O)Nc2nc(-c3ccc(F)cc3)cs2)ccc1OCC(=O)N1CCOCC1
d. O=C(NCc1ccc(F)cc1)C1CCN(S(=O)(=O)N2CCCC2)CC1
e. COc1cccc(CN2CCN(S(=O)(=O)c3ccc(Cl)s3)CC2)c1
Answer: e. COc1cccc(CN2CCN(S(=O)(=O)c3ccc(Cl)s3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CN2CCN(S(=O)(=O)c3ccc(Cl)s3)CC2)c1
COc1cccc(CN2CCN(S(=O)(=O)c3ccc(Cl)s3)CC2)c1
1-(5-chlorothiophen-2-yl)sulfonyl-4-[(3-methoxyphenyl)methyl]piperazine