Problem statement: Answer the multiple-choice question.
Question: Which compound has a 16.845\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(CSc1nc2nn(-c3ccccc3)c(=O)c-2c2n1CCCCC2)Nc1ccc(F)cc1F
b.) COc1cccc(CN2CCNC(=O)C2CC(=O)NCCc2nc(C)c(C)s2)c1OC
c.) Cc1ccc(-c2nn(-c3ccc(F)cc3)cc2C(=O)N2CCN(C3CCS(=O)(=O)C3)CC2)cc1
d.) CC(=O)N(Cc1c(C#N)c2ccccc2n1C)c1ccccc1
e.) COc1ccc(NC(=O)NCCCCc2ccccc2)c(OC)c1
Answer: b. COc1cccc(CN2CCNC(=O)C2CC(=O)NCCc2nc(C)c(C)s2)c1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CN2CCNC(=O)C2CC(=O)NCCc2nc(C)c(C)s2)c1OC
COc1cccc(CN2CCNC(=O)C2CC(=O)NCCc2nc(C)c(C)s2)c1OC
2-[1-[(2,3-dimethoxyphenyl)methyl]-3-oxopiperazin-2-yl]-N-[2-(4,5-dimethyl-1,3-thiazol-2-yl)ethyl]acetamide