Problem statement: Answer the MCQ question.
Question: Which compound has a -11.666\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) O=C(CCS(=O)(=O)c1ccc(Br)cc1)NC1CCCC1
b) COc1ccc(-c2nc(CS(=O)CC(=O)NC3CCC(C)CC3)c(C)o2)cc1OC
c) COc1ccc(CCNC(=O)c2ccc(NS(=O)(=O)c3c(C)noc3C)cc2)cc1OC
d) CCOC(=O)CNC(=O)/C(=C\c1ccc(F)cc1)NC(=O)c1ccccc1
Answer: d. CCOC(=O)CNC(=O)/C(=C\c1ccc(F)cc1)NC(=O)c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)CNC(=O)/C(=C\c1ccc(F)cc1)NC(=O)c1ccccc1
CCOC(=O)CNC(=O)/C(=C\c1ccc(F)cc1)NC(=O)c1ccccc1
ethyl 2-[[(E)-2-benzamido-3-(4-fluorophenyl)prop-2-enoyl]amino]acetate