Problem statement: Answer the MCQ question.
Query: Which drug has a 12.963\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CCCOc1ccc(N/C=C/C(=O)c2ccc(OC)c(OC)c2)cc1
[b] COc1ccccc1CN1C(=O)CCC1(C)C(=O)NCc1cccnc1
[c] CCOc1ccc(C(CCc2ccccc2)NC(=O)c2ccccc2)cc1OCC
[d] COc1cccc(CNC(=O)C2CCCN(S(=O)(=O)c3ccc4c(c3)C(C)(C)C(=O)N4C)C2)c1
[e] CC(=O)c1cccc(NC(=O)NCc2cccnc2)c1
Answer: d. COc1cccc(CNC(=O)C2CCCN(S(=O)(=O)c3ccc4c(c3)C(C)(C)C(=O)N4C)C2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)C2CCCN(S(=O)(=O)c3ccc4c(c3)C(C)(C)C(=O)N4C)C2)c1
COc1cccc(CNC(=O)C2CCCN(S(=O)(=O)c3ccc4c(c3)C(C)(C)C(=O)N4C)C2)c1
N-[(3-methoxyphenyl)methyl]-1-(1,3,3-trimethyl-2-oxoindol-5-yl)sulfonylpiperidine-3-carboxamide