Problem statement: Answer the multiple-choice question.
Query: Which drug has a -6.540\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Cc1cc(S(=O)(=O)N2CCCCC2CCNC(=O)C(=O)NC2CC2)ccc1F
(b) O=C(Cc1ccccn1)c1ccc(Cl)cc1
(c) O=C(Nc1ccccc1)c1cc(S(=O)(=O)N2CCOCC2)cs1
(d) O=C(NC1CCCc2c1cnn2-c1ccccc1F)c1ccccc1N1CCOCC1
(e) COc1ccc(OC)c(NC(=O)c2ccno2)c1
Answer: c. O=C(Nc1ccccc1)c1cc(S(=O)(=O)N2CCOCC2)cs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1ccccc1)c1cc(S(=O)(=O)N2CCOCC2)cs1
O=C(Nc1ccccc1)c1cc(S(=O)(=O)N2CCOCC2)cs1
4-morpholin-4-ylsulfonyl-N-phenylthiophene-2-carboxamide