Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -25.114\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1c(CC(=O)N2CCN(C(=O)C3COc4ccccc4O3)CC2)c(=O)oc2c(C)c(O)ccc12
b) COC(=O)C1=C(C(=O)OC)[C@@H]2N(C)c3ccc(OC)cc3[C@@]23C[C@@H](C(=O)OC)N(C(=O)NC2CCCCC2)C3=N1
c) CC(C)CN(C(=O)c1cccc(S(=O)(=O)N2CCN(Cc3ccccc3)CC2)c1)C1CCS(=O)(=O)C1
d) CN1CC(C(=O)c2ccc(F)cc2)C(c2c(F)cccc2Cl)C1
e) O=C(NC1CCCCC1)C(c1ccccc1)N(C(=O)c1csnn1)C1CCCC1
Answer: d. CN1CC(C(=O)c2ccc(F)cc2)C(c2c(F)cccc2Cl)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1CC(C(=O)c2ccc(F)cc2)C(c2c(F)cccc2Cl)C1
CN1CC(C(=O)c2ccc(F)cc2)C(c2c(F)cccc2Cl)C1
[4-(2-chloro-6-fluorophenyl)-1-methylpyrrolidin-3-yl]-(4-fluorophenyl)methanone