Problem statement: Answer the MCQ question.
Query: Which compound has a 1.975\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1ccc(NC(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)cc1OC
b.) COCCn1c(N)c(N(Cc2ccccc2)C(=O)c2ccc(C#N)cc2)c(=O)[nH]c1=O
c.) Cc1ccnc(NC(=O)Cc2ccc(F)cc2)n1
d.) COCCNc1nc2c(S(=O)(=O)c3cc(C)ccc3C)nnn2c2ccccc12
e.) CC(C)c1nc2ccc(Br)cn2c1NC1CCCC1
Answer: b. COCCn1c(N)c(N(Cc2ccccc2)C(=O)c2ccc(C#N)cc2)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCn1c(N)c(N(Cc2ccccc2)C(=O)c2ccc(C#N)cc2)c(=O)[nH]c1=O
COCCn1c(N)c(N(Cc2ccccc2)C(=O)c2ccc(C#N)cc2)c(=O)[nH]c1=O
N-[6-amino-1-(2-methoxyethyl)-2,4-dioxopyrimidin-5-yl]-N-benzyl-4-cyanobenzamide