Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 26.963\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CC(=O)Nc1cccc(C(=O)NCC2(N3CCCCC3)CCCCC2)c1
[b] O=C(c1cn(-c2ccccc2)nc1-c1cccnc1)N1CCCC(C(F)(F)F)C1
[c] S=c1[nH]nc(C2CCCCC2)n1/N=C/c1cccc(Cl)c1Cl
[d] O=C(Cc1ccccc1)Nc1ccccc1CO
[e] CCOC(=O)N1CCN(C(=O)CN(C)S(=O)(=O)c2ccc3c(c2)c(=O)n(C)c(=O)n3C)CC1
Answer: e. CCOC(=O)N1CCN(C(=O)CN(C)S(=O)(=O)c2ccc3c(c2)c(=O)n(C)c(=O)n3C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)CN(C)S(=O)(=O)c2ccc3c(c2)c(=O)n(C)c(=O)n3C)CC1
CCOC(=O)N1CCN(C(=O)CN(C)S(=O)(=O)c2ccc3c(c2)c(=O)n(C)c(=O)n3C)CC1
ethyl 4-[2-[(1,3-dimethyl-2,4-dioxoquinazolin-6-yl)sulfonyl-methylamino]acetyl]piperazine-1-carboxylate