Problem statement: Answer the multiple-choice question.
Question: Which drug has a 8.096\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1ccc(NS(=O)(=O)c2cccc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c2)cc1
b: O=[N+]([O-])c1ccc2ccn(C3OCC(O)C(O)C3O)c2c1
c: CC1CCCN(c2ccc(C(=O)NCc3cccs3)cn2)C1
d: O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCCN(c2ccc(C(F)(F)F)cn2)CC1
e: COc1ccc(NC2CC(=O)NC2=O)cc1
Answer: d. O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCCN(c2ccc(C(F)(F)F)cn2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCCN(c2ccc(C(F)(F)F)cn2)CC1
O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCCN(c2ccc(C(F)(F)F)cn2)CC1
1-[4-(trifluoromethyl)phenyl]sulfonyl-4-[5-(trifluoromethyl)pyridin-2-yl]-1,4-diazepane