Problem statement: Answer the MCQ question.
Question: Which compound has a 5.862\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CC(CC(=O)NC1CCSC1=O)c1ccccc1
[b] COc1ccccc1NC(=O)Cn1c(CN2CCCCC2)nc2ccccc2c1=O
[c] CCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(S(C)(=O)=O)cc1)C2
[d] COc1cc2c(-c3ccc4cc[nH]c4c3)c(-c3ccc(C#N)cc3)oc(=O)c2cc1OC
[e] CCCN1CC2CCCC3(C1)C(=O)NC1(CCCCC1)N=C23
Answer: c. CCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(S(C)(=O)=O)cc1)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(S(C)(=O)=O)cc1)C2
CCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(S(C)(=O)=O)cc1)C2
methyl (1R,5S)-3-(4-methylsulfonylphenyl)-8-(propylcarbamoyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate