Task: Answer the MCQ question.
Question: Which drug exhibits a -0.940\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1cccc(OC)c1C(=O)NNS(=O)(=O)c1ccc2ccccc2c1
[b] COc1ccc(NS(=O)(=O)c2ccc(C)c(NC(=O)CN3C(=O)NC4(CCCC4)C3=O)c2)cc1
[c] CCn1c(=O)c2ccccc2n(Cc2cccc(C)c2)c1=O
[d] O=C(Cc1ccc(S(=O)(=O)N2CCOCC2)s1)Nc1ccccc1Br
[e] CCOc1cc(S(=O)(=O)NCC2CCCO2)ccc1F
Answer: b. COc1ccc(NS(=O)(=O)c2ccc(C)c(NC(=O)CN3C(=O)NC4(CCCC4)C3=O)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NS(=O)(=O)c2ccc(C)c(NC(=O)CN3C(=O)NC4(CCCC4)C3=O)c2)cc1
COc1ccc(NS(=O)(=O)c2ccc(C)c(NC(=O)CN3C(=O)NC4(CCCC4)C3=O)c2)cc1
2-(2,4-dioxo-1,3-diazaspiro[4.4]nonan-3-yl)-N-[5-[(4-methoxyphenyl)sulfamoyl]-2-methylphenyl]acetamide