Problem statement: Answer the MCQ question.
Question: Which drug has a 5.549\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C(Nc1cccnc1)C1CCN(S(=O)(=O)c2cccc3nonc23)CC1
b) c1ccc(CN2CCN(c3nc4ccccc4c4ccccc34)CC2)cc1
c) COC(=O)CNC(=O)C1Nc2ccc(OC(F)(F)F)cc2C2C=CCC12
d) Cc1cc(C)n(-c2ccc(C(=O)Nc3ccc(C)c(S(=O)(=O)N(C)C)c3)cc2)n1
e) Cc1ccc(S(=O)(=O)N(c2nc(NC(C)C)nc(NC(C)C)n2)n2cnnc2)cc1
Answer: c. COC(=O)CNC(=O)C1Nc2ccc(OC(F)(F)F)cc2C2C=CCC12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)CNC(=O)C1Nc2ccc(OC(F)(F)F)cc2C2C=CCC12
COC(=O)CNC(=O)C1Nc2ccc(OC(F)(F)F)cc2C2C=CCC12
methyl 2-[[8-(trifluoromethoxy)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carbonyl]amino]acetate