Problem statement: Answer the MCQ question.
Query: Which drug has a 11.184\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O=C(COC(=O)C12CC3CC(CC(C3)C1)C2)Nc1ccc(N2CCOCC2)cc1
[b] CCCNC(=O)N1C2=NC(C(=O)OC)=C(C(=O)OC)[C@@H]3N(Cc4ccccc4)c4ccccc4[C@]23C[C@H]1CO
[c] CCOC(=O)C1C(=O)C=C(c2ccc(C)cc2)CC1c1ccco1
[d] CCOc1ccccc1NC(=O)CCCNC(=O)Cn1cnc2sc(C)c(C)c2c1=O
[e] COc1c2ccoc2c(OC[C@@H](O)C(C)(C)OC)c2oc(=O)ccc12
Answer: c. CCOC(=O)C1C(=O)C=C(c2ccc(C)cc2)CC1c1ccco1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1C(=O)C=C(c2ccc(C)cc2)CC1c1ccco1
CCOC(=O)C1C(=O)C=C(c2ccc(C)cc2)CC1c1ccco1
ethyl 6-(furan-2-yl)-4-(4-methylphenyl)-2-oxocyclohex-3-ene-1-carboxylate