Problem statement: Answer the multiple-choice question.
Question: Which compound has a 19.317\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1ccc(S(=O)(=O)Nc2cccc(C(=O)NCC(c3ccccc3)N(C)C)c2)cc1F
b) CC(=O)C1=C(C)NC(SCc2ccc(C#N)cc2)=C(C#N)C1c1ccco1
c) Cc1onc(-c2c(Cl)cccc2Cl)c1COC(=O)c1ccc(Cl)cc1[N+](=O)[O-]
d) COc1ccc(N2CCN(C(=O)c3ccc(-c4nc5ccccc5s4)o3)CC2)cc1
e) COC(=O)[C@@H](NC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O)C(C)C
Answer: e. COC(=O)[C@@H](NC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O)C(C)C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)[C@@H](NC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O)C(C)C
COC(=O)[C@@H](NC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O)C(C)C
methyl (2S)-3-methyl-2-[(9,10,10-trioxothioxanthene-3-carbonyl)amino]butanoate