Problem statement: Answer the MCQ question.
Question: Which drug has a 10.847\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1cc(NC(=S)Nc2ccccn2)cc(OC)c1
b. CCOC(=O)C1CCN(S(=O)(=O)c2c(C)n(C)c(=O)n(C)c2=O)CC1
c. CCNS(=O)(=O)c1ccc(CCC(=O)N2CCN(C(=O)OCC)CC2)cc1
d. CCOC(=O)Nc1ccc2c(c1)OCO2
e. O=C(Nc1cc(C(F)(F)F)ccc1N1CCOCC1)c1ccc2ccccc2n1
Answer: c. CCNS(=O)(=O)c1ccc(CCC(=O)N2CCN(C(=O)OCC)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCNS(=O)(=O)c1ccc(CCC(=O)N2CCN(C(=O)OCC)CC2)cc1
CCNS(=O)(=O)c1ccc(CCC(=O)N2CCN(C(=O)OCC)CC2)cc1
ethyl4-[3-[4-(ethylsulfamoyl)phenyl]propanoyl]piperazine-1-carboxylate