Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 3.435\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CN1CCN(c2c(C#N)c(C(F)(F)F)nn2C)CC1
[b] CCOC(=O)CNc1c(-c2ccc(OC)cc2)nc2ccc(Cl)cn12
[c] CC(=O)OC(C(=O)NCc1ccc(F)cc1)c1ccccn1
[d] C=CCN(C(=O)Cn1c(C(=O)OC)cc2oc(C)cc21)c1ccccc1
[e] COc1ccc(C(c2nnnn2Cc2ccc(F)cc2)N2CCN(c3ccccc3)CC2)cc1
Answer: e. COc1ccc(C(c2nnnn2Cc2ccc(F)cc2)N2CCN(c3ccccc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(c2nnnn2Cc2ccc(F)cc2)N2CCN(c3ccccc3)CC2)cc1
COc1ccc(C(c2nnnn2Cc2ccc(F)cc2)N2CCN(c3ccccc3)CC2)cc1
1-[[1-[(4-fluorophenyl)methyl]tetrazol-5-yl]-(4-methoxyphenyl)methyl]-4-phenylpiperazine