Problem statement: Answer the multiple-choice question.
Question: Which drug has a 3.644\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1ccc(C2=NOC3(CC(=O)N(c4ccc(Cl)cc4)C3=O)C2)c(OC)c1
b: COCc1cc(C)nc(N2CCN(Cc3ccccc3)CC2)c1C#N
c: O=C(CCc1nnc(CCC2CCCCC2)o1)N1CCCC(CN2CCCC2)C1
d: Cc1c(NC(=O)c2coc(=O)c(Br)c2)c(=O)n(-c2ccccc2)n1C
e: CC(=O)c1ccc(N2CCN(C(=O)CCC(=O)c3cccs3)CC2)cc1
Answer: d. Cc1c(NC(=O)c2coc(=O)c(Br)c2)c(=O)n(-c2ccccc2)n1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1c(NC(=O)c2coc(=O)c(Br)c2)c(=O)n(-c2ccccc2)n1C
Cc1c(NC(=O)c2coc(=O)c(Br)c2)c(=O)n(-c2ccccc2)n1C
5-bromo-N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-6-oxopyran-3-carboxamide