Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -5.368\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1nnc(NC(=O)NCN2C(=O)C3C4C=CC(C4)C3C2=O)s1
b. COCCCN1CC(=O)N2C(c3cccc(OC)c3)c3[nH]c4ccccc4c3C[C@H]2C1=O
c. O=C(CCN1C(=O)C2C3C=CC(C3)C2C1=O)N1CCN(c2ccc(F)cc2)CC1
d. Clc1ccccc1-c1nnc(-c2cccs2)o1
e. CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=S)NC(=O)c2ccco2)c1
Answer: c. O=C(CCN1C(=O)C2C3C=CC(C3)C2C1=O)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCN1C(=O)C2C3C=CC(C3)C2C1=O)N1CCN(c2ccc(F)cc2)CC1
O=C(CCN1C(=O)C2C3C=CC(C3)C2C1=O)N1CCN(c2ccc(F)cc2)CC1
4-[3-[4-(4-fluorophenyl)piperazin-1-yl]-3-oxopropyl]-4-azatricyclo[5.2.1.02,6]dec-8-ene-3,5-dione