Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 4.380\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCOc1ccccc1C(=O)Nc1cc(OC)ccc1OC
b) CC(NC(=O)c1noc2c1CCCCC2)c1ccccc1
c) COc1ccc(N2CCC(CNS(=O)(=O)c3cccc(C(F)(F)F)c3)C2)cc1
d) COC(=O)c1ccc(-n2c(C)nc3ccccc3c2=O)cc1
e) COc1ccc(C(=O)c2oc3ccccc3c2N)cc1
Answer: c. COc1ccc(N2CCC(CNS(=O)(=O)c3cccc(C(F)(F)F)c3)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCC(CNS(=O)(=O)c3cccc(C(F)(F)F)c3)C2)cc1
COc1ccc(N2CCC(CNS(=O)(=O)c3cccc(C(F)(F)F)c3)C2)cc1
N-[[1-(4-methoxyphenyl)pyrrolidin-3-yl]methyl]-3-(trifluoromethyl)benzenesulfonamide