Problem statement: Answer the multiple-choice question.
Question: Which drug has a -1.659\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1cccc(-c2nc(CS(=O)CC(=O)NCc3cccs3)c(C)o2)c1
b COc1cc(Cl)c(C)cc1NC(=O)CNC(=O)Cn1cnc2ccccc2c1=O
c COc1cccc(-c2nnc(SCC(=O)N(C(C)C)C(C)C)o2)c1
d COc1cccc(/C=C/C(=O)OCC(=O)NCCC2=CCCCC2)c1
e CCCCCC1CC1C(=O)N/N=C/c1ccc(N(C)C)cc1
Answer: d. COc1cccc(/C=C/C(=O)OCC(=O)NCCC2=CCCCC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(/C=C/C(=O)OCC(=O)NCCC2=CCCCC2)c1
COc1cccc(/C=C/C(=O)OCC(=O)NCCC2=CCCCC2)c1
[2-[2-(cyclohexen-1-yl)ethylamino]-2-oxoethyl] (E)-3-(3-methoxyphenyl)prop-2-enoate