Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 19.513\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a CCN1C(=O)/C(=C/c2ccc(N3CCCC3)cc2)NC1=S
b COc1ccc(CN2C(=O)c3ccccc3C2C(=O)NCC2CCCO2)c(OC)c1
c COc1ccc(C(=O)NCCCN2CCOCC2)cc1OC
d CC1(C)Cc2cccc(OCC(=O)Nc3ccccc3N3CCOCC3)c2O1
e O=C(NCCCN1CCCC1)c1ccc(Cn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1
Answer: e. O=C(NCCCN1CCCC1)c1ccc(Cn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCCCN1CCCC1)c1ccc(Cn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1
O=C(NCCCN1CCCC1)c1ccc(Cn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1
4-[(6-bromo-4-oxo-2-sulfanylidene-1H-quinazolin-3-yl)methyl]-N-(3-pyrrolidin-1-ylpropyl)benzamide