Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -41.603\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Cc1ccc2c(=O)cc(C(F)F)oc2c1
(b) COC(=O)C1=CN(C2CC2)C=C(C(=O)OC)C1c1ccc(C(=O)OC)cc1
(c) CN1CCN(c2ccccc2NC(=O)c2cccc(OCc3ccccc3)c2)CC1
(d) N#C/C(=C/c1ccc(-c2ccc(S(N)(=O)=O)cc2)o1)c1nc2ccccc2s1
(e) Cc1c(CCO)c(=O)n(C)n1C(=O)c1ccc(Cl)cc1
Answer: c. CN1CCN(c2ccccc2NC(=O)c2cccc(OCc3ccccc3)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1CCN(c2ccccc2NC(=O)c2cccc(OCc3ccccc3)c2)CC1
CN1CCN(c2ccccc2NC(=O)c2cccc(OCc3ccccc3)c2)CC1
N-[2-(4-methylpiperazin-1-yl)phenyl]-3-phenylmethoxybenzamide