Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 8.420\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. c1ccc2sc(NC3=NCN(C4CCCCC4)CN3)nc2c1
b. Cc1ccccc1Oc1ccc(Oc2ccccc2C)nn1
c. O=C(/C=C/c1ccco1)NC(=S)Nc1cc(-c2nc3ccccc3s2)ccc1Cl
d. CCCCc1c(O)nc(SCC(=O)Nc2ccc3c(c2)CCC3)[nH]c1=O
e. COC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c(N)sc(C)c12
Answer: e. COC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c(N)sc(C)c12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c(N)sc(C)c12
COC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c(N)sc(C)c12
methyl 5-amino-3-(4-methoxyphenyl)-7-methyl-4-oxothieno[3,4-d]pyridazine-1-carboxylate