Problem statement: Answer the multiple choice question.
Query: Which compound has a -4.202\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COC(=O)COc1cccc(/C=N/NC(=O)CCSc2ccccc2)c1
b. O=C1CC(c2cccnc2)c2cc3c(cc2N1)OCCO3
c. O=C(COc1ccc(Cl)cc1)N/N=C/c1cccc2cccnc12
d. CN(C)CCc1nn[nH]n1
e. CC(=O)N1CCC2(CC1)C/C(=N\NC(=S)Nc1ccc(C)cc1)c1cc(O)ccc1O2
Answer: e. CC(=O)N1CCC2(CC1)C/C(=N\NC(=S)Nc1ccc(C)cc1)c1cc(O)ccc1O2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=O)N1CCC2(CC1)C/C(=N\NC(=S)Nc1ccc(C)cc1)c1cc(O)ccc1O2
CC(=O)N1CCC2(CC1)C/C(=N\NC(=S)Nc1ccc(C)cc1)c1cc(O)ccc1O2
1-[(E)-(1'-acetyl-6-hydroxyspiro[3H-chromene-2,4'-piperidine]-4-ylidene)amino]-3-(4-methylphenyl)thiourea