Problem statement: Answer the multiple-choice question.
Question: Which compound has a 12.230\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(C(=O)Cc2cnn(-c3ccccc3)c2)c(O)c1
b) Cc1ccccc1N/N=C/c1ccc(N2CCOCC2)cc1
c) Cn1cccc1C(=O)NC(=O)COC(=O)CNC(=O)CNC(=O)c1ccc(Cl)cc1Cl
d) Cc1ccccc1C(=O)NC(=S)Nc1ccc(Oc2ccc(Cl)cc2)cc1
e) COC(=O)c1ccc(-c2nc3cc(N)ccc3o2)cc1
Answer: a. COc1ccc(C(=O)Cc2cnn(-c3ccccc3)c2)c(O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)Cc2cnn(-c3ccccc3)c2)c(O)c1
COc1ccc(C(=O)Cc2cnn(-c3ccccc3)c2)c(O)c1
1-(2-hydroxy-4-methoxyphenyl)-2-(1-phenylpyrazol-4-yl)ethanone