Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a 7.250\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CCn1c(N)nc2c1c(=O)n(C)c(=O)n2C
[b] Cc1nc2sc(C(c3ccco3)N3CCC(C)CC3)c(O)n2n1
[c] Cc1cc(/C=C2/C(=O)NC(=O)N(Cc3ccco3)C2=O)c(C)n1-c1ccccc1
[d] Brc1ccc(-c2cn3c(n2)SCC3)cc1
[e] COc1cc(OC)c2c(-c3ccccc3)cc(=O)oc2c1C(CCN1CCN(c2ccccc2)CC1)c1ccc(N(C)C)cc1
Answer: e. COc1cc(OC)c2c(-c3ccccc3)cc(=O)oc2c1C(CCN1CCN(c2ccccc2)CC1)c1ccc(N(C)C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(OC)c2c(-c3ccccc3)cc(=O)oc2c1C(CCN1CCN(c2ccccc2)CC1)c1ccc(N(C)C)cc1
COc1cc(OC)c2c(-c3ccccc3)cc(=O)oc2c1C(CCN1CCN(c2ccccc2)CC1)c1ccc(N(C)C)cc1
8-[1-[4-(dimethylamino)phenyl]-3-(4-phenylpiperazin-1-yl)propyl]-5,7-dimethoxy-4-phenylchromen-2-one