In 1821, Itard published a major work on otology, describing the results of his medical research based on over 170 detailed cases. He is credited with the invention of the Eustachian catheter, which is sometimes known as "Itard's catheter". Numbness in the tympanic membrane during otosclerosis is referred to as the "Itard-Cholewa Symptom".
He was also an educator of deaf children, and tried his educational theories in the celebrated case of Victor of Aveyron. However, his efforts with Victor ended up with disappointing results.