An initial study was undertaken on the use of Botox Type A injected into the upper limb muscles of 10 children followed by 10 sessions of OT and PT and then followed by 10 sessions of neuromuscular electrical stimulation on the wrist extensors. Results indicated an improvement in hand function. A trend was seen in a reduction of spasticity and an increase in range of motion but no significant difference was noted. The researchers plan on doing a future study to determine the exact effects of the treatments.
Reference: Rodríguez-Reyes, Gerardo; Alessi-Montero, Aldo; Díaz-Martínez, Leticia; Miranda-Duarte, Antonio; Pérez-Sanpablo, Alberto Isaac Botulinum Toxin, Physical and Occupational Therapy, and Neuromuscular Electrical Stimulation to Treat Spastic Upper Limb of Children With Cerebral Palsy: A Pilot Study Artificial Organs, Volume 34, Number 3, March 2010 , pp. 230-234(5)