Crohn's is a severe, chronic inflammatory bowel disease. It causes inflammation,
, and bleeding in the digestive tract. It usually affects the end portion of the small intestine called the ileum. However, any part of the digestive tract can be affected, from the mouth to the anus.
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The cause of Crohn's disease is not known.
Inflammatory bowel diseases
and Crohn's disease) seem to run in some families. Some researchers think that it is due to a reaction to a virus or bacteria. The immune system overreacts and causes damage to the intestines.
Factors increase your chance of getting Crohn's include:
The doctor will ask about your symptoms and medical history. A physical exam will be done.
Tests may include:
If you are diagnosed with Crohn's disease, follow your doctor's
Treatment may include:
Your doctor may recommend that you avoid foods that provoke symptoms.
These foods are different for each person. They may include:
There are many types of medicines that are used to treat Crohn's disease. Examples of these medicines include:
Very severe Crohn's may not improve with medicines. You may be advised to have the severely diseased section of your intestine removed. The two remaining healthier ends of the intestine are then joined together. You are still at high risk for recurrence of the disease elsewhere.
Surgery may also be done if you have an obstruction or fistulas.
Untreated Crohn's disease may lead to:
There are no guidelines for preventing Crohn's disease because the cause is unknown.
American Gastroenterological Associationhttp://www.gastro.org/
Crohn's and Colitis Foundation of Americahttp://www.ccfa.org/
Crohn's and Colitis Foundation of Canadahttp://www.ccfc.ca/
National Institute of Diabetes and Digestive and Kidney Diseases website. Available at:
Accessed July 20, 2008.
Disease information. Crohn's and Colitis Foundation of America website. Available at:
. Accessed July 20, 2008.
DynaMed Editorial Team. Crohn's disease. EBSCO DynaMed website. Available at:
. Updated June 16, 2011. Accessed June 17, 2011.
Sleisenger & Fordtran's Gastrointestinal and Liver Disease.
8th ed. St. Louis, MO: Mosby; 2005.
Ferri F, ed.
Ferri’s Clinical Advisor 2010.
Philadelphia, PA: Mosby Elsevier; 2009.
Goroll AH, Mulley AG.
Primary Care Medicine
. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins;2000.
Hou JK, Abraham B, El-Serag H. Dietary intake and risk of developing inflammatory bowel disease: a systematic review of the literature.
Am J Gastroenterol.
Inflammatory bowel disease. American Gastroenterological Society website. Available at:
. Accessed July 20, 2008.
10/2/2009 DynaMed's Systematic Literature Surveillance
: FDA approves new drug to treat psoriasis. US Food and Drug Administration website. Available at:
. Published September 25, 2009. Accessed October 2, 2009.