MIT 7.91J Foundations of Computational and Systems Biology, Spring 2014
View the complete course: http://ocw.mit.edu/7-91JS14
Instructor: David Gifford
Prof. Gifford talks about library complexity as it relates to genome sequencing. He explains how to create a full-text minute-size (FM) index, which involves a Burrows-Wheeler transform (BWT). He ends with how to deal with the problem of mismatching.
License: Creative Commons BY-NC-SA
More information at http://ocw.mit.edu/terms
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Tagged under: DNA sequencing,genome,short read alignment,read mapping,library complexity,full-text minute-size index,BWT,sequencing adapter,Poisson,Burrows-Wheeler transform
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