I know that Mari posted information for you. Did it help you? I am just going to give you some brief explanations of your tests. If, after the explanation and reading the post referred to you, you still have more questions about the tests, please let us know and we will answer them as best as we can.
Each of the tests you listed are used in conjunction with other tests and/or with each other in order to help doctors determine if there is an auto-immune disorder occurring within your body. No one test alone is enough to make this determination.
ESR = erythrocyte sedimentation rate (ESR). This test measures inflammation in the body. Lupus is a disease that causes inflammation throughout the body. If the ESR levels are high, then doctors know that there is some inflammation.
CRP = C-reactive Protein. This is another test to determine inflammation in the body. C-reactive protein is produced by the liver. The level of CRP rises when there is inflammation throughout the body.
ANA =The ANA (antinuclear antibody) is used to detect auto-antibodies that react against components of the nucleus of the body's cells. Most people with lupus test positive for ANA. Usually, along with the ANA test, your doctor will take other tests that can help determine the presence of three specific types of anti-bodies that are found in Lupus patients: anti-dsDNA (anti-double-stranded DNA), anti-Sm (anti-Smith antibodies), and anti-RNP antibodies. The anti-dsDNA and anti-RNP tests confirm whether there are antibodies being produced to the genetic material in the cell. The anti-Sm test measures if there are antibodies against a certain protein found in the nucleus of cells. When either the anti-dsDNA or the anti-Sm antibody test is positive, a person is usually considered to have SLE. Knowing which particular antibody is responsible for the positive ANA test can help determine which autoimmune disease is present.
Seruf R F = Rheumatoid Factor.
Rhematoid factor is an antibody that is measurable in the blood and it can bind to other antibodies. Rheumatoid factor is an antibody that is not usually present in the normal individual. Lupus is considered a rheumatic disease (diseases that cause inflammation, pain & swelling of the joints and muscles).High levels of rheumatoid factor indicates the presence of a rheumatic disease.
ENA = Extractable Nuclear Antigen.
The ENA panel is usually ordered following a positive ANA test in people who have clinical signs of an auto-immune disorder. The 4-test ENA panel is used to help diagnose mixed connective tissue disease (MCTD), Lupus, and Sjogren syndrome. The 6-test ENA can also help identify scleroderma and polymyositis.
Some of your tests results are high, some are negative. This is why your doctor says they are conflicting one another. However, this is not at all unusual in Lupus patients. You may have Lupus without high levels of inflammation or without some of the antibodies. Then again, you may have some auto-immune issues occurring, but not Lupus. I am sure that your doctor will want to run further tests or he may decide to just begin to treat the symptoms that you are displaying.
I hope that this has been somewhat helpful to you. Please let us know if you need more information.
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