Mortality and death cases of hand foot and mouth disease reported in China, 2008 - 2010
摘要: 目的 了解全国2008 - 2010年手足口病死亡水平和死亡病例流行病学特点,为防治手足口病死亡病例的发生提供科学依据。 方法 从中国疾病预防控制中心《疾病监测信息报告管理系统》下载2008 - 2010年全国手足口病报告病例进行描述流行病学分析。 结果 近3年全国手足口病死亡水平和死亡病例呈明显上升趋势,2010年死亡人数定基比高达718%,3年间均为男性死亡率高于女性。死亡病例的特征为发病到死亡时间中位数为3 d、死亡病例年龄小于未死亡病例、确诊时间长于未死亡病例、实验室诊断比例高于未死亡病例。死亡病例多发生在0~2岁,发生高峰集中在4-7月。全国连续3年报告死亡病例较多的省为广东、河北;连续2年报告死亡率较高的省(自治区)为海南、广西。 结论 我国手足口病死亡水平和死亡病例上升趋势的遏制有赖于防控措施的全面落实。及时就医、缩短确诊时间可为患者争取宝贵的救治时间。Abstract: Objective To understand the mortality and epidemiological characteristics of death cases of hand foot mouth disease (HFMD) in China from 2008 to 2010 and provide scientific evidence for the prevention and control of HFMD. Methods Descriptive epidemiological analysis was conducted on the incidence data of HFMD in China during this period collected from national disease reporting information system. Results The mortality as well as death cases of HFMD increased obviously from 2008 to 2010. The relative ratio with fixed base of death cases of HFMD in 2010 reached 718%, the mortality in males was higher than that in females. The median of interval between onset and death of the death cases was 3 days. Compared with recovered cases, the death cases were younger and had longer interval between onset and diagnosis, and the laboratory confirmation rate was higher among them too. Most death cases were young children aged 0-2 years and the peak of the death occurred during April-July. High death number was reported in Guangdong and Hebei for 3 consecutive years, and the high mortality was reported in Hainan and Guangxi for 2 consecutive years. Conclusion It is essential to fully implement the prevention and control measures for HFMD, seek medical service as early as possible and shorten the interval between onset and diagnosis to stop the increase of mortality and death cases of HFMD in China.
 Sun JL, Zhang J. A review on the advancement of epidemiology on hand-foot-mouth disease
[J]. Chinese Journal of Epidemiology,2009,30(9):973-976. (in Chinese) 孙军玲,张静. 手足口病流行病学研究进展
 Chinese Center for Diseases Control and Prevention. China Information System Diseases Control and Prevention V2.0. Http://126.96.36.199. 中国疾病预防控制中心.中国疾病预防控制信息系统疾病监测信息报告管理系统.Http://188.8.131.52.
 Urashima M, Shindo N, Okabe N. Seasonal models of herpangina and hand-food-mouth disease to simulate annual fluctuations in urban warming in Tokyo
[J].JpnInfect Dis, 2003,56(2):48-53.
 Wu YD, Shang SQ, Chen ZM, et al. Analysis of the epidemic characteristics of the etiological agents in children with hand,foot and mouth disease and its clinical significance
[J]. Chinese Journal of Pediatrics,2010,48(7):535-539.(in Chinese) 吴亦栋,尚世强,陈志敏,等. 手足口病病原体流行特征分析及临床意义
 Ministry of Health. Hand-food-mouth disease control and prevention guidelines
[S].Beijing: Ministry of Health,2009.(in Chinese) 中华人民共和国卫生部. 手足口病预防控制指南
 Ministry of Health. Management measurement on the report of public health emergence event and infectious disease
[S].Beijing: Ministry of Health, 2006.(in Chinese) 卫生部.突发公共卫生事件与传染病疫情监测信息报告管理办法
 Ministry of Health. The announcement by general office of ministry of health to enhance prevention and control on HFMD and other infectious disease caused by human enterovirus
[S].Beijing: Ministry of Health, 2008.(in Chinese) 卫生部.卫生部办公厅关于加强手足口病等肠道病毒感染性疾病防控工作的通知
- 文章访问数: 2544
- HTML全文浏览量: 88
- PDF下载量: 679
- 被引次数: 0