It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Prednisone and plaquenil pregnancy Plaquenil long term Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. When lichen planus develops in the mouth, it often does not cause pain or other symptoms. If this is the case, treatment may not be necessary. When lichen planus causes pain, burning, redness, blisters, sores, or ulcers, it can be treated. Some medicine is applied to the sores. Other medicine comes in pill form. Mouth sores due to lupus are not considered life-threatening. However, they can lead to discomfort and low self-esteem, which can affect the overall health of the affected individual. Lupus mouth sores are often seen on the roof of the mouth, but they can also occur inside the cheeks, gums, or lips. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil to treat mouth disease Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Lichen planus Diagnosis and treatment Atovaquone proguanil chloroquine doxycycline or mefloquineChloroquine readymade sigma Treatment. Lichen planus on the skin often clears up on its own in months to years. If the disease affects your mucous membranes, it tends to be more resistant to treatment and prone to recur. Whatever treatment you use, you'll need to visit your doctor for follow-up appointments about once a year. Lichen planus - Diagnosis and treatment - Mayo Clinic. Dealing with Lupus Mouth Sores Causes, Treatment, and Prevention. Plaquenil Use in Autoimmune Diseases. It has not helped me yet with my mouth and lips or being tired but since I haven't reached the six month mark I still have hope. I am with the others and encourage you to start Plaquenil. I think you will feel much better and slowing the progression of this disease is important. Your doctor may prescribe a mild medication first, such as hydroxychloroquine, sold as Plaquenil ®. This medication was originally formulated to prevent and treat malaria, but is now also classified as a disease-modifying antirheumatic drug, or DMARD, which means it treats the underlying disease rather than its symptoms. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.