Great Slave Lake is the second-largest lake in the Northwest Territories of Canada (after Great Bear Lake), the deepest lake in North America at 614 metres (336 fathoms; 2,010 ft), and the ninth-largest lake in the World. It is 480 km (300 mi) long and 19 to 109 km (12 to 68 mi) wide. It covers an area of 27,200 km2 (10,502 sq mi) in the southern part of the territory. Its given volume ranges from 1,070 km3 (260 cu mi) to 1,580 km3 (380 cu mi) and up to 2,088 km3 (501 cu mi) making it the 10th or 12th largest.
The lake shares its name with the Slavey First Nations. Towns situated on the lake include: Yellowknife, Hay River, Behchoko, Fort Resolution, Lutselk'e, Hay River Reserve, Dettah and N'Dilo.