ROLE OF DIFFERENT NEUROTRANSMITTERS IN ANXIETY: A SYSTEMIC REVIEWAbstract
Anxiety is a persistent feeling of dread, apprehension and impending disaster, or tension and uneasiness. The reported prevalence rates of psychiatric morbidity in the Indian industrial population range from 14-37%. Anxiety disorders may develop from a complex set of risk factors including genetics, brain chemistry, personality and life events. It is a specific class of psychopathology characterized by future-oriented apprehension and elevated threat value associated with physical, social, and mental stimuli. According to multiple-systems, individual shows different types of symptoms i.e. Cognitive, Physiological and Behavioral during anxiety. Abnormal functioning of neurochemicals as well as abnormal chemoreceptor reactivity leads to anxiety. There are various neurotransmitters that are involved in anxiety such as serotonin, glutamate, gamma-amino butyric acid, Cholecystokinnin, Adenosine etc. Some are inhibitory and some are excitatory. These neurotransmitters might play role in upregulation or downregulation of anxiety disorders. This review article gives a bird’s eye view of neurotransmitters involved in anxiety.
Sandeep Kaur and Rajmeet Singh *
Department of Pharmacology, G.H.G. Khalsa College of Pharmacy, Gurusar Sadhar, Ludhiana, Punjab, India.
23 July, 2016
27 September, 2016
28 November, 2016
01 February, 2017