It is only a matter of time before autonomous vehicles surpass human driven vehicles in terms of passenger and pedestrian safety. We can expect that some cities and regions in the world will be dominated by AVs.
When this occurs to a sufficient degree, it is more than merely probable that the remaining human drivers will be seen as a nuisance, since they cause the greatest proportion of road risk. People will react two ways to this idea.
Fear, because the notion speaks of a future drastically different from the last hundred years, the culture of which has been influenced by powerful advertising connecting a person's virility, femininity, or autonomy with their automobiles
Humor, because it is so obvious to anyone who drives that so many of the other drivers are a nuisance — Those that are brutally self-honest would see that, at certain times, they themselves are nuisances.
It is very probable that laws against human driving will eventually start in one or two jurisdictions where critical proportions of well designed AVs on the roads have been reached. From there it will spread.
It would not be surprising if, in fifty years, when the world population is at least double, vehicular fatalities will have radically decreased because of AVs. If nothing interferes to stop such a trend, the jurisdictions that continue to permit unregulated driving would be then considered uncivilized and dangerous.
We can imagine travel brochures saying, "Vacation in Ireland, now sidewalk-safe," because Ireland had passed a law ten years prior to gradually reduce the number of registered vehicles with steering wheels to zero. Sidewalk safe might not be the term, but some marketing term for AV only roadways will be coined to sell tourists and families.