Creatinine - a substance secreted by each body and is involved in energy metabolism.Creatinine is produced in muscle tissue, and then released into the blood.Its content is conditioned by the volume of muscle mass, so the rate of creatinine in the blood is lower in women than in men, because the female dominated by fat mass rather than muscle.
Number of creatinine in the blood plasma can vary dramatically due to the fact that muscle mass is built up slowly.
average rate of creatinine in the blood of women is 43-81 mmol / l.The boundaries of creatinine in men: 63-107 mmol / l;infants 0-12 months - 46-104 mmol / l;in children from one to 15 years - 24-62 mmol / l.
Elevated creatinine may be people who consume a lot of animal fats and proteins.If this is the case, there will be increased creatinine, urine and blood at the same time.
creatinine may rise with a sharp increase in physical activity, severe muscle injuries, dehydration, kidney failure, radiation sickness, as well as
Reduced creatinine can be in the first two trimesters of pregnancy, with serious starvation with severe weight loss, nutrition only plant-based foods, muscular dystrophy, during treatment with certain medications.
displayed creatinine excretion by the kidneys.If the content does not meet the standards can be suspected renal disease.In acute renal failure, elevated creatinine, pyelonephritis, and always and continues to grow rapidly level.
creatinine in urine
norm: men - 8,7-17,6 mmol;Women: 7,2-15,8 mmol.
The urine output should all creatinine, about two grams per 24 hours.The rate of creatinine in the blood of women and men is a more accurate measure compared with the standards of its content in the urine.
When you need to be tested for creatinine?
- for analysis are sent to people passing examinations because of suspicion of nephrology diagnoses or have kidney problems;
- when examining the human kidney for donation;
- the treatment with drugs that have toxic effects on the kidneys.
analysis of the level of creatinine
The rate of creatinine in the blood of women and men is determined by sample Rehberg, it also allows you to determine the level in the urine.Before you take these tests, it is necessary to suspend the reception of such medicines as cortisol, thyroxin, corticotropin.Preparation for the analysis is to avoid the protein food 10 hours before giving blood.
survey begins with the patient drinking a pint of water and accurately pinpoint the time of urination.Then half an hour later typed blood from a vein, after another 30 minutes, going to a urine test.The result was the most authentic, also takes into account the personal data: age, height, weight, the patient's lifestyle.
If serum creatinine increased, the first thing you need to visit the doctor, nephrologist.