Strontium is a naturally occurring mineral present in water and food. Trace amounts of strontium
are found in the human skeleton. Strontium has an affinity for bone and is taken up at the bone
matrix crystal surface. The influence of strontium on the bone metabolism has been researched
since the 1950's. Studies indicate that strontium positively affects bone metabolism to promote
bone formation and decrease bone resorption, leading to normalized bone density.
The Role of Stable Strontium in Human Bone
Strontium is found naturally in the human skeleton. The level of strontium in bone tissue is
approximately 3.5% of the calcium content of bone. Strontium taken orally through the diet and
from supplements is preferentially incorporated into the teeth and bones. Research suggests that
the oral absorption of strontium is dependent on age and decreases with increasing age.
Scientists have suggested two methods of absorption of strontium from the gastrointestinal
tract: passive diffusion and carrier-mediated absorption. In adults, strontium is absorbed to a
lesser extent than calcium, possibly due to the larger molecular size of strontium in comparison
to the calcium molecule. Both calcium and strontium compete with one another for absorption in
the intestines. High dietary intake of calcium has been shown to reduce concurrent absorption of
strontium. It has been proposed that when both elements are present together, twice the amount
of calcium is absorbed from the intestines in comparison with strontium.
Animal studies suggest that extremely high dietary intakes of strontium, in the absence of
adequate calcium intake, can actually disturb bone mineralization. At such concentration levels
strontium replaces calcium ions in bone. The unbalanced incorporation of strontium into bone
tissue in the place of calcium may cause a disturbance of the bone lattice, resulting in
decreased bone mineral density. It is precisely for this reason that calcium intake must be
adequate when supplementing with strontium.
Further studies in animals reveal that strontium given as a part of the normal diet (when
calcium intake is adequate) may have profound effects on bone formation and density. Oral
administration of strontium doses to rats was shown to enhance the rate of bone formation and
trabecular bone density.
-Helps maintain strong, healthy bones.*
Helps Maintain Strong, Healthy Bones* Mechanism of Action
Strontium is a bone-seeking mineral incorporated by ionic substitution for calcium onto the
crystal surface of bone. Researchers have looked at the therapeutic potential of strontium based
on in vitro, animal and human studies. After assessing and analyzing the results of several
investigations, scientists theorize that strontium may benefit bone health via a two-pronged
effect. It appears that strontium interacts with the cells responsible for the normal bone
remodeling process. The cells responsible for bone formation are known as osteoblasts, and the
cells responsible for bone breakdown, or resorption, are called the osteoclasts. Strontium may
stimulate the replication of pre-osteoblasts, leading to an increased proliferation of
osteoblasts (cells that build bone). This causes an increased synthesis of bone matrix. In terms
of effects on osteoclasts (cells responsible for bone resorption), in vitro work shows that
strontium directly inhibits their activity and prevents bone breakdown.
Animal studies have shown that supplementation with strontium is extremely beneficial as a bone
In one such study, strontium administered at low doses has been shown to increase the number of
bone forming sites in thighbones of adult rats, without adverse effects on the mineral content
of bone or mineralization of the organic bone matrix. A second study in rats indicated that
strontium could reverse bone loss associated with a deficiency of the hormone estrogen in
Multiple clinical studies utilizing different forms of strontium have been conducted since the
1950s. Stable strontium as gluconate, carbonate, lactate and chloride have all been used in
various trials that have reported efficacy of supplemental strontium in promoting healthy bones.
Regardless of the form, it is the elemental strontium itself that exerts the positive effect on
bone. While all of the various forms have a bioavailability of between 25 and 30%, gastric
tolerance is reportedly better with strontium citrate9, the form used in Strontium Bone
Serving Size: 2 capsules
Servings Per Container: 60
Amount Per Serving % Daily Value *
Strontium 680 mg *
(elemental) (from 1944mg Strontium citrate)
* Percent Daily Value not established.
Modified cellulose (vegetarian capsule), cellulose, magnesium stearate (vegetable source).
Take two capsules daily with or without food. For maximum absorption and benefit, do not take at
the same time as calcium or milk products. Be sure to take at least the RDA of calcium and
The best way to take your strontium is in the morning on an empty stomach as you will digest it
quickly and you can then after one hour have your breakfast and take all your vitamins. Take the
two caps at the same time. If you cannot swallow capsules please open capsule and put into apple
sauce but not into any dairy products as the calcium in it will compete with the Strontium Bone
KEEP OUT OF REACH OF CHILDREN. Supplementing with strontium is an effective means for supporting
bone health and optimal bone density. When taken orally as recommended, strontium is well-
tolerated and very safe. It is important to ensure calcium and vitamin D intakes are adequate
when supplementing with strontium. This is underscored by earlier research on animals suggesting
that increasing the intake of strontium via diet may demineralize bone when calcium is
deficient. In rats with chronic kidney failure, strontium has been shown to cause osteomalacia,
a condition in which bone is softened due to lack of mineral content. For this reason, people on
kidney dialysis should not use strontium supplements. There are no published reports of toxic
effects in humans due to strontium overdosing.
To prevent mouth or throat irritation do not open capsule and pour contents directly into
Individuals with a severe renal impairment should check with a healthcare practitioner before
using this product
Does Not Contain:
Milk, egg, wheat, gluten, corn, soy, sugar, sweeteners, starch, salt, or preservatives