Urease test to detect H. pylori infection.A biopsy of the gastric mucosa is taken during upper gastrointestinal endoscopy and the biopsy is placed in the jelly-filled well of the CLOtest slide. The slide is incubated at 37oC. If the bacterium is in the biopsy it releases urease which splits urea in the jelly, releasing ammonia which turns the jelly red. No change of color means that the germ is not present in the biopsy.
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