African Water Mongoose Skin Fibroblast Cells (A. P. Mongoose Line)
The A. P. Mongoose cell line was established at The Naval Biosciences Laboratory (NBL) in Oakland, California from the skin of an African water mongoose (Atilax paludinosus). The cells exhibit fibroblast morphology, and similar to other fibroblast lines, are among the easiest cells to grow in culture. Cell biologists hypothesize that the ability of fibroblasts to grow so readily outside of the body is associated with their central role in the healing of wounds, which necessitates their proliferation when confronted with injury or other less than optimal conditions. Fibroblasts are also generally considered to exhibit relatively solitary lifestyles, which some have suggested may also be a factor in their favorable growth in culture.