What is Autologous Transplantation?
Autologous stem cell transplant is taken from your own stem cells before it is destroyed by cancer treatment. Your stem cell cells are extracted from your bone marrow or blood and then frozen. After receiving high-dose chemo and / or radiation therapy, these cells are returned to body temperature and returned to you.
An advantage of autologous stem cell transplantation is the use of your own cells. This means that your immune system will not reject the given cells or the cells that are given will not attack your body.
A possible disadvantage is the removal of the stem cells and the removal of cancer cells and then return to your body. To prevent this, doctors can give you cancer drugs or reduce the number of cancer cells that may be present by treating stem cells.
This type of transplantation is mainly used in the treatment of multiple myeloma with some leukemia and lymphomas. Sometimes, especially in children, it is used in the treatment of other types of cancers.
Stem cell transplantation is performed in two ways: allogeneic transplantation and autologous transplantation. Allogeneic transport to stem cell transplantation from relatives or non-relatives; the patient’s own stem cells are collected and given to him again after the treatment is completed is called autologous transplant. Although there is a high risk of complications due to shortage of donor stem cell transplantation, semi-compatible transplants can also be performed. Such transplants from the patient’s mother, father or adult child are called haploidentic transplantation. Especially if allogeneic transplantation is involved in radiotherapy, reproductive cells of men and women in reproductive age can be damaged. Therefore, these people are offered the chance to store sperm and eggs. There is usually no such risk in autologous transplantation.
THE FIRST STEP OF THE TREATMENT
Assuming that the first step of the treatment is to prepare the patient for transplantation. Dr. Dr. Ahmet Ifran, for this reason to eliminate the current disease and the patient’s own bone marrow to eliminate high-dose chemotherapy, as well as chemotherapy, as well as radiotherapy is applied and continues:
Kök Stem cells taken as an allogeneic transplant from the donor are given by the vein of the patient, and the stem cells find the bone marrow and settle there. The amount of stem cells to be given is decided according to the weight of the patient and transplanted approximately 2.5 million stem cells per kilogram. About two weeks in the bone marrow, the patient begins to make enough blood for a lifetime. This situation is called ’engraftment in or il bone marrow retention Bu. Stem cells here both reproduce themselves and produce new stem cells. These intact stem cells also provide the treatment of the disease. ”
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