(1644–1718) was the English founder of Pennsylvania
may also refer to:
- William Penn (Royal Navy officer)
(1621–1670), English admiral under Cromwell and Charles II and the father of William Penn
- William Penn Jr.
(1681–1720), eldest surviving son of William Penn, founder of Pennsylvania
- William Penn (athlete)
(1883–1943), American tug-of-war competitor
- William Evander Penn
(1832–1895), Texas Baptist evangelist and minister
- William S. Penn
(born 1949), mixed-race Nez Perce author and English professor at Michigan State University
- William F. Penn
(1871–1934), black physician in Atlanta, Georgia
- William Penn (pen name), pen name used by activist Jeremiah Evarts (1781–1831) in his essays against Indian removal
- William Penn (cricketer)
(1849–1921), Kent county cricketer
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