pyogenes can asymptomatically colonize humans, and may cause invasive diseases, such as bacteremia, pneumonia, necrotizing fasciitis, and streptococcal toxic shock syndrome [1, 2].
pyogenes accounts for 2-5% of cases of bacterial pneumonia in the early 20th century .
What respiratory disease can be caused by Streptococcus pyogenes in rare cases?
pyogenes was a common cause of epidemic outbreaks and community-acquired pneumonia (CAP) [1–3]. Currently S. pyogenes is considered a rare cause of community acquired pneumonia, being a clinical entity seen only sporadically after an influenza infection [4–5].
Where is Streptococcus pyogenes found?
Epidemiology. S. pyogenes (group A β-hemolytic streptococcus) can be found in the oropharynx of more than 20% of children and a smaller percentage of adults.
Can Streptococcus pyogenes kill you?
pyogenes infections and rheumatic fever disease alone causes 233,000 deaths (8). 1,800 invasive S. pyogenes disease-related deaths are reported in the USA yearly, necrotizing fasciitis kills about 30% of patients and streptococcal toxic shock syndrome has a mortality rate of 30-70% (3, 11, 12).
What are the sequelae of Streptococcus pyogenes infection?
Acute Streptococcus pyogenes infections may take the form of pharyngitis, scarlet fever (rash), impetigo, cellulitis, or erysipelas. Patients may also develop immune-mediated sequelae such as acute rheumatic fever and acute glomerulonephritis.