Residential Acinetobacter baumannii usually associated with respiratory tract, urinary tract, skin and soft tissue and bloodstream infections and multidrug resistant Acinetobacter baumannii is difficult to treat.
Generally benign in normal healthy people, but can be an opportunistic pathogen in persons suffering from various diseases. Infections can occur in damaged tissues caused by burn or surgery, and also in a respiratory tract or eye. Especially in cystic fibrosis and immuno-depressed patients; or in patients with fatal septicemia, endocarditis, peritonitis, malignant external otitis, chronic inflammatory otitis media, or spinal cord osteomyelitis.
Encompass Escherichia, Salmonella, and Enterobacter cloacae are major pathogens which cause intestinal diseases or food poisoning: Enterobacter cloacae is a major pathogen of nosocomial infections which can cause pneumonia and incur death after septicemia.
Residential bacteria in the oral cavity and intestine can lead to a nosocomial and opportunistic infection. Common infections include a respiratory tract infection (leading to gastroenteritis), urinary tract infections, cerebromeningitis, septicemia and acute pneumonia.
Symptoms of infection with N. gonorrhoeae differ, depending on the site of infection. Note also that 10% of infected males and 80% of infected females are asymptomatic. Men who have had a gonorrhea infection have a significantly increased risk of having prostate cancer. Infection of the genitals can result in a purulent (or pus-like) discharge from the genitals, which may be foul-smelling. Symptoms may include inflammation, redness, swelling, and dysuria N. gonorrhoeae can also cause conjunctivitis, pharyngitis, proctitis or urethritis, prostatitis, and orchitis
According to 2008 NHSN (National Healthcare System Network) data, 13% of E. coli and Klebsiella infections, 17% of Pseudomonas infections, and 74% of Acinetobacter baumannii infections were of Multiple Drug Resistant Gram negative bacteria. Almost all of these infectious pathogens were reported to be Carbapenem resistant strains.
Resistance to the three representative antibiotics for Gram negative infection treatment- Carbapenem, Aminoglycosides and Fluoroquinolone- has already spread amongst the Acinetobacter and Pseudomonas strains.