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The inner bark of the lapacho tree plays a central role in the herbal medicine of several South American indigenous peoples. They use it to treat cancer as well as a great variety of infectious diseases.
There has been very little scientific investigation of lapacho as a whole herb. However, an enormous amount of scientific interest has focused on three constituents of lapacho: lapachol, lapachone, and isolapachone. The relevance of these findings to the use of lapacho itself remains unclear.
Lapacho contains many components that don't dissolve in water, so making tea from the herb is not the best idea. It's better to take capsulized powdered bark; a typical dose is 300 to 500 mg 3 times daily. The inner bark of the lapacho tree is said to be the most effective part of the plant.