GENUS NAME: metronidazole
Business name: Flagyl
DRUG CLASS AND MECHANISM: Metronidazole is an antibiotic effective against anaerobic bacteria and certain parasites. Anaerobic microorganisms are single celled, living beings that flourish in environments in which there’s little oxygen (surroundings). Germs may cause disorder in the abdominal cavity (bacterial peritonitis), liver (liver abscess), and pelvic girdle (abscess of oviducts).
Ameba and Giardia lamblia are parasites that can make stomach pain and diarrhea in infected people.
Trichomonas is a parasite that causes irritation of the vagina (vaginitis). Metronidazole blocks a few of inside the cells and the parasites resulting in their own passing.
Flagyl Side Effects
Metronidazole is a good antibiotic and is usually well taken with proper use.
Minor unwanted effects include:
Reduction of desire
A metallic flavor
Scarcely a rash
Serious negative effects of uncommon as well as the drug needs to be discontinued if these signs appear:
Harm of nerves causing tingling and numbness of extremities
Metronidazole might be taken with or without any food. In a medical facility, metronidazole may be administered to treat severe diseases. The liver is mainly in charge of discharging metronidazole in the entire body, and doses may have to be decreased in-patients.
Metronidazole regimens are utilized. Some illustrations are given below.
Amebic dysentery: 750 mg three times daily for 5 -10 days
Amebic liver abscess: 500-750 mg 3 times daily for 5-10 days
Anaerobic diseases: 7.5 mg/kg orally or by injection every 6 hrs. for 7 to 10 days not to exceed 4 grams daily.
Bacterial vaginosis: 750 mg (prolonged release tablets) once-daily for seven days or 500-mg twice-daily for 1 week or 2-g single-dose or one applicator-total of 0.75% vaginal gel, once or twice-daily for 5 times.
Clostridium difficile disease: 250-500 milligrams orally 4 times every day or 500- 750 three times daily
Giardia: 250-mg orally 3 times daily for 5 times Helicobacter pylori: 800 1500 milligrams orally daily for a number of days in conjunction with other medications.
Pelvic inflammatory disease (PID): 500-mg orally twice-daily for 2 weeks in conjunction with other medications.
Trichomoniasis: 2-g single-dose or 1g Rosacea: use external gel 0.75-1% once daily
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