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What is the cortex of the adrenal gland derived from?
What is the medulla of the adrenal gland derived from?
neuroectoderm (neural crest cells)
What is the shape of the right and left adrenal glands?
- Right = small triangular
- Left= larger semilunar
What are the three zones of the adrenal cortex?
(Go Find Randy's adrenal cortex)
What hormone is secreted by the glomerulosa layer of the adrenal cortex?
(Globular minearals are salty)
What hormone is secreted by the fasciculata layer of the adrenal cortex?
What hormones are secreted by the reticularis layer of the adrenal cortex?
sex hormones (estrogen, progesterone, testosterone)
What is the function of the glomerulosa layer of the adrenal cortex?
regulate Na resorption which causes increases water retention and BP
What controls the function of the glomerulosa later of the adrenal cortex?
renin secreted from the juxtaglomerular apparatus of the kidney
What part of the adrenal cortex increases lipolysis, glycogenesis, increased gluconeogenesis?
Fascicuata layer (cortisol)
What are estrogen, progesterone, and testosterone all derived from?
What does the adrenal medulla secrete?
What part of the nervous system does the adrenal medulla belong to?
sympathetic nervous system
What disease presents with increased perspiration, heart palpitation, paroxysms of hypertension, pressure headaches?
What is the etiology of pheochromocytoma?
- Caused by an adrenal medulla tumor
- 10% bilateral
- 10% malignant
- 10% outside adrenal gland
- 10% familial
What disease presents with low BP, low Na, High k, high BUN?
What disease is caused by an overfunction zona glomerulosa?
What disease presents with high Na, high BP, water retention?
What causes cushings syndrome?
Excess cortisol production by the Zona fasciculata
What produces ACTH and what part of the adrenal medulla is controlled by it?
- Anterior pituitary gland
- zona fasciulata production of cortisol
What is the purpose of cortisol?
increases blood glucose levels
what is the effect of over production of ACTH?
Increased production of melanocyte stimulating hormone