A copper-carrying Trojan horse
Illustration created for Prof. Michael Johnson from the Department of Immunology at the University of Arizona, as part of the Animation Lab #SeeingDiversity project (2020)
Prof. Johnson's research focuses on mechanisms of metal toxicity in bacteria. This specifically illustrates how a copper ionophore can be used to kill bacteria through ionophore/copper synergy, identifying a new potential class of antimicrobials.
Menghani SV, Rivera A, Neubert M, Hagerty JR, Lewis L, Galgiani JN, Jolly ER, Alvin JW, Johnson MDL. Demonstration of N,N-Dimethyldithiocarbamate as a Copper-Dependent Antibiotic against Multiple Upper Respiratory Tract Pathogens. Microbiol Spectr. 2021 Oct 31;9(2):e0077821. doi: 10.1128/Spectrum.00778-21.
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Audience: Lay public
Media: Autodesk Maya, Adobe Photoshop