This article links self vs non-self identification via the conserved molecular mechanisms of gut microbes (like E. coli) to disorders of the immune system that have typically been attributed to mutation-initiated natural selection. No experimental evidence supports claims associated with mutation-driven evolution.
Excerpt: “Precise detection of specific antibodies is fundamental in diagnosing a wide range of diseases – and testing for antibodies using known”
My comment: Reports like this one exemplify why others should already have learned that adaptive evolution is nutrient-dependent and pheromone-controlled. Unfortunately, theorists have been convinced they should ignore accurate claims and simply accept — with no experimental evidence to support them — the claims based on mutation-driven evolution.
Those claims have prevented scientific progress for several decades, and they may keep theorists from making scientific progress in the future. At some point, biologists will make no further attempts to explain the biological basis of adaptations to anyone who believes that theory trumps what is already known about cause and effect.
For contrast, the method of disease detection this article details will obviously be useful “…to reveal previously unknown environmental factors involved in disease.”
That’s because the method incorporates what is currently known about biologically-based adaptations and does not include anything that theorists attribute to mutations and disease.
Mutations and disease are not adaptive, which explains why there is no mention of mutations in the entirety of this excellent report. Environmental factors involved in disease act via epigenetic effects that may be linked to mutations when the mutations are not eliminated by nutrient-dependent pheromone-controlled natural genetic variation.