Epigenetic effects relate to the switching ‘on’ or ‘off’ of genes without affecting the DNA itself. For example, every individual is unique according to their individual DNA composition. It contains all instructions for how the organism functions (how our body functions, including our skin, collagen and elastin synthesis) as well as how we look. However, DNA is a highly complex sequence with several chemical ‘tags’ along its structure that can be marked ‘readable’ or ‘not readable’.
When ‘readable’, that function is considered switched ‘on’; and certain bodily functions will occur. When ‘readable’ or ‘on’, it doesn’t actually change the DNA sequence, but instead, makes a part of the structure active and its instructions accessible.
The epigenome regulates this functionality, as does the much more widely known, micro-RNA. In this way, epigenetics utilizes the DNA coding already present in the human body but can be affected by:
− Lifestyle, including stress effects and poor sleep
− Environment, especially where protective mechanisms need to be activated; for example, due to UV exposure or other environmental impacts
− Cellular metabolism and division
Where these impacts are negative and/or the cells age, the epigenome tags relative to skin cell renewal, collagen or elastin synthesis may be turned ‘off’ or at least not function as they did when the organism was younger. These results in a reduction of cell turnover, renewal, and proliferation – which ultimately lead to other age-related effects, we commonly see, such as less supple complexion and the formation of fine lines and wrinkles.
Now fortunately, we have a new science that can effectively reverse the signs of aging for healthy and younger-looking skin. Let's understand that thoroughly…
|In the personal care industry, epigenetic science refers to the use of specific active ingredients that are able to modify cellular activity for visible skin benefits. For example, some beneficial cellular modifications specific to materials used in cosmeceutical personal care products may include:
− Cell proliferation stimulated to improve tissue regeneration
− Regeneration of skin cells in-spite of their age – enabling older skin cells to mimic the activity of younger skin cells, which results in a more youthful appearance, and/or
− Stimulating skin renewal and turnover
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Currently, more than 50 countries have adopted medicinal cannabis programmes while Canada, Uruguay and 15 US states have legalized its recreational use, with Mexico and Luxembourg having political debates as to whether to follow that path. - UN News & UN CND (Commission on Narcotic Drugs)
This market shift toward the wider cultural acceptance of therapeutic cannabis is finding consumer brands rushing to market to fulfil marketplace demands with unsufficient scientific alignment. The reality is, and many science institutions (FDA, UK Commission, WHO) have agreed, that there has not been sufficient testing, length of study, nor broad-scope subjective data collected on longterm human effects that is available to us today.
Innovation Superclusters are engines of economic growth. Built around industries of the future, Superclusters can accelerate transformation and drive system-level innovation. The Canadian Cosmetic Cluster is an internationally recognized hub that participates in global trade initiatives and provides service to local and international cosmetic companies. Collaborating, developing, supporting with academia, capital and national policy, Canada can become a centre for global Superclusters.
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