An estimated 43.5 million Americans provide in-home, long-term care for older adult family members with a chronic illness. In a new JAMA survey, caregivers are typically women who spend about 20 to 40 hours a week providing care. Most caregivers feel abandoned and unrecognized by the health care system. Spousal caregivers face greater challenges than caregivers helping a parent for a variety of reasons, one of which is that they tend to be older. Many caregivers don’t know about, or take advantage of, services and support systems such as respite care, help with non-medical services such as housekeeping and cooking, counseling, and more. The Caregiver’s Handbook, a Special Health Report from Harvard Medical School, includes detailed information that can help women and men provide better care for their loved ones and take care of themselves.