Acid chondroitin is found in animal cartilage, and is found in nasal septum and laryngeal bone of large domestic animals. It is reported that the nasal septum of pigs contains about 41%. The drug chondroitin sulfate is A mixture of various chondroitin sulfate such as thiocomb chondroitin A and chondroitin sulfate C, which are extracted from cartilage.
Characteristics of Chondroitin sulfate sodium: it is a white powder with strong water absorption and is easily soluble in water to form a viscous liquid, but insoluble in organic solvents such as ethanol, acetone and ether. Its salts are stable to heat.
Preparation method of Chondroitin sulfate sodium: Preparation and tablet of sulfate cartilage, its production process mainly includes dilute alkali extraction method, details are as follows:
Porcine throat (nose) cartilage, leaching sodium hydroxide filtration, leaching solution, enzymatic hydrolysis of hydrochloric acid, trypsin 53 ~ 54℃, hydrolysate, adsorption activity of clay, activated carbon, precipitation of sodium chloride, ethanol, PH 6.3 ~ 7, precipitate, dry anhydrous ethanol 60 ~ 65℃, dry product, preparation of sodium chloride, P value 5.5, injection.