Intertrigo develops when friction and trapped moisture in intertriginous areas cause skin maceration and inflammation with formation of patches or plaques. Infection by bacteria and yeast is also common. Typical locations are the inframammary, infrapannicular, interdigital, axillary, infragluteal, and genitocrural folds.
Diagnosis of intertrigo is based on clinical appearance; potassium hydroxide wet mounts and cultures can guide treatment.
Differential diagnosis of intertrigo includes
If no bacteria or yeast are detected, drying agents should be therapeutic. Effective options include over-the-counter antiperspirants containing 20% aluminum chloride and Burow solution compresses.
If bacteria or yeast are present, topical antibacterial lotions or antifungal creams are given in addition to drying agents (see Table: Options for Treatment of Superficial Fungal Infections*).