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A protein found in osteoblasts and dentin; contains γ-carboxyglutamyl residues; has a role in mineralization and calcium ion homeostasis.
Synonym(s): bone Gla protein
A calcium-binding substance produced by osteoblasts that is essential to bone mineralization and can be used as a biomarker for osteoporosis. It may also act as a hormone to increase insulin production and insulin sensitivity.
a protein found in the extracellular matrix of bone and dentin and involved in regulating mineralization in the bones and teeth.
BGLAPA gene on chromosome 1q25-q31 that encodes a protein which constitutes 1–2% of bone protein, which binds strongly to apatite and calcium.
Protein found in osteoblasts and dentin.
n vitamin Kdependent calcium-binding protein synthesized by osteoblasts and found primarily in bone. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism.
a product of the resorption of bone.