Scientists agree that polyphenols are essential for the treatment and prevention of chronic diseases due to their antioxidant, anti-inflammatory, immunomodulating, and chemopreventive properties. Among all food plants, sorghum has the highest polyphenolic content, especially in certain grain varieties. Interestingly, the leaf sheath of the Sorghum bicolor plant from West Africa contains three times the amount of polyphenolic compounds compared to the grains.
For centuries, traditional medicine practitioners have utilized the Sorghum bicolor leaf sheath to treat and prevent various chronic diseases, including arthritis, infertility, diabetes, sickle cell disorder, hypertension, heart diseases, anemia, and cancer. Building upon this traditional knowledge, a supplement called Jobelyn has been developed from the Sorghum bicolor leaf sheaths, which have been used by the people of southwestern Nigeria for centuries to address diverse health issues such as arthritis, stroke, diabetes, cardiovascular disorders, hypertension, and cancer. Over the course of more than 20 years, extensive research and scientific investigation have been conducted to unravel the mysteries of this herb.
Jobelyn, derived from Sorghum bicolor leaf sheath, contains an impressive 106.86 mg/g (10,686 mg/100g) of phenolics. With the exception of clove and dried peppermint, it is the richest source of polyphenols and phenolic plants in the world. In fact, the National Cancer Institute has included Sorghum bicolor supplement made from Sorghum bicolor leaf sheaths in their dictionary of drugs, praising its richness in polyphenols and polyphenolic acids, as well as its potential for antioxidant, anti-inflammatory, immunomodulating, and chemopreventive activities.
This herbal-based nutritional supplement contains various phytochemicals, including phenolic acids and polyphenols like proanthocyanidins. Notably, it is particularly abundant in 3-deoxyanthocyanins such as luteolinidin and apigeninidin, which have shown the ability to induce apoptosis and inhibit cell proliferation in cancer cells by stimulating apoptosis promoter genes and downregulating certain apoptosis inhibitor genes. Additionally, the strong antioxidant nature of these phytochemicals enables them to scavenge free radicals and prevent tissue damage. Furthermore, the intake of this supplement has been found to modulate the immune system by boosting the activity of natural killer (NK) cells and initiating the activation of macrophages.
For more information on the research conducted, a partial view can be found at: https://g.co/kgs/9EZiHj
● A powerful supplement made of sorghum bicolor leaf extract
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Sorghum Research Reviews and Meta-analysis