Bacillus bombysepticus was first separated from the sick silkworm larvae cadavers and identified by Hartman in 1931 (Hartman 1931). B. bombysepticus is a Gram-positive bacterium and can produce spores and parasporal crystals. B. bombysepticus can infect silkworm and will result in a typical symptom of a disease: a peutz first appears on its thoracoabdominal region or the first 1–3 abdominal aspect, and then expands to the whole body (Huang et al., 2009).
Phylogenetic tree of 16S rRNA sequences and survival curve of Bb infection the silkworm (Huang et al., 2009)
(a) Phylogenetic tree with the sequences of 16S rRNA gene of Bb and its related species. Bb can produce spores and parasporal crystal. (b) Survival curve of Bb oral infection silkworm on day 3 of the fifth instar. Control 1: ddH2O feed silkworm rearing under the condition of temperature of 30°C and humidity of 90%. Control 2: ddH2O feed silkworm rearing under the condition of temperature of 25°C and humidity of 70%. Induced 1: Bb feed silkworm rearing under the condition of temperature of 30°C and humidity of 90%. Induced 2: Bb feed silkworm rearing under the condition of temperature of 25°C and humidity of 70%. (c) Natural infection and oral infection both can cause silkworm cuticle peutz.
Data summary of B. bombysepticus Wang
|Data Type||Records||Length (bp or aa)|
- Hartman E. A flacherie disease of silkworm caused by Bacillus bombysepticus. Lignan Science Journal. 1931, 10: 279–289.
- Huang L., Cheng T., Xu P., Cheng D., Fang T., Xia Q. A genome-wide survey for host response of silkworm, Bombyx mori during pathogen Bacillus bombysepticus infection. PLoS ONE. 2009, 4:E8098.
- Cheng,T., Lin,P., Jin,S., Wu,Y., Fu,B., Long,R., Liu,D., Guo,Y., Peng,L. and Xia,Q. Complete Genome Sequence of Bacillus bombysepticus, a Pathogen Leading to Bombyx mori Black Chest Septicemia. Genome Announc. 2014, 2(3). pii: e00312-14. doi: 10.1128/genomeA.00312-14.