Clomid clomiphene is an oral medication that induces, or regulates, ovulation. Understanding how Clomid works is important to understanding how most fertility drugs effect ovulation.
Clomid exerts its effects at the hypothalamus, the gland that signals the pituitary to produce FSH, LH, and estrogen. FSH products stimulate the ovaries directly and the response is dose related.
Clomid fights for estrogen receptors making the hypothalamus to “find” lower estrogen levels. Healthy follicles release estrogen which is controlled by the hypothalamus and FSH release is changed depending on the level of estrogen.
When the level of estrogen enhances, FSH production reduces. In contrast, decreased estrogen levels trigger an increase in FSH and following follicular stimulation.
Clomid has been among the first infertility medicines in clinical practice and was originally intended as a contraceptive pill.
Clomid women health ovulation inducing abilities were detected, and the doctors started to use it in women suffering from anovulation or irregular menstruation.
As the use of Clomid went on, the doctors revealed its adverse effects, such as hot flashes, ovarian enlargement, abdominal pain, sickness, vomiting, vision problems, head pain, etc.
Clomid adverse effects are generally not serious and go away once the treatment is stopped.
The drug can’t stimulate the ovaries directly, and as soon as ovulation becomes regular, there is no need to enhance the Clomid dose.
If ovulation doesn’t happen at the dose of 50mg, doctors will tell you to buy Clomid online and double or triple the dose. Pregnancies generally happen within the first 3 ovulatory cycles, and cheap Clomid treatment after this time is not advised. In some cases, 1-2 ovulatory cycles are enough to define the right dose for the patient.
Clomid cycles may be accompanied by the ultrasound to find out the best time for having sex.
The ovarian follicles and the uterine lining are measured by means of ultrasound as well. The right growth of the follicles can be shown by means of ultrasound and by defining the level of estradiol.
As a rule, Clomid clomiphene is efficient within the first 3-6 cycles, however, there are some patients who have used Clomid for 12 cycles or more.
Therefore, it is essential to visit an expert in fertility, during the treatment with Clomid. Such a long treatment will hardly be effective. Moreover, it is costly, and may cause serious adverse effects.
Clomid is also intended for the treatment of PCOS but many doctor are currently using metformin that can normalize ovulation by changing insulin levels, thereby reduce androgens (men hormones).
In some cases, this drug is prescribed by non-experts without a sperm test. Infertility doctor always ask for a sperm test before prescribing any drug to a woman.
A certain degree of male infertility can be found in about 50% of all infertile couples and it should be excluded before starting the Clomid treatment.
Clomid can’t directly affect the ovaries. However, it normalizes ovulation and generally doesn’t increase the amount of eggs.
Actually, as soon as your ovulation is back to normal, there is no point in enhancing the dose.
In contrast to generic Clomid, FSH can’t stimulate the ovaries directly and leads to the increase in the number of eggs, necessary for an IVF cycle.
FSH doses and follicular development are closely monitored by the fertility doctor, which may change the dose if necessary.
Depending on various specific factors, FSH IUI may be tried; however, IVF is often the most suitable option. In some cases, generic Clomid may be used in IUI but it is not as efficient as FSH.