As a result of the developments in current treatment modalities, remarkable improvements have been made in the number of survived childhood malignancies. Increased awareness of the impact of various cytotoxic treatments on gonadal function has now resulted in a surge in the number of patients seeking help to preserve their fertility.
Cryopreservation of embryos is a standard technique for fertility preservation when there is adequate time for ovarian stimulation. If patients have no partner or unwilling to use donor sperm, oocytes can be frozen instead. Current experience about ovary cryopreservation and transplantation is limited. Nevertheless, at present, it is the only fertility preservation procedure that can be offered to prepubertal girl and can be implemented without any delay in treatment. The main goal of this group is to preserve ovarian tissue by using the best cryopreservation protocol and also tries to set up the in vitro culture of human follicle and investigate different molecular mechanisms which are involved in these procedures.