Finding a cause of neurodevelopmental disorders
Neurodevelopmental disorders arising from rare genetic mutations can cause atypical cognitive function, intellectual disability and developmental delays, yet it is unclear why and how this happens. Now, Assistant Professor Diana Hargreaves, first author Fangjian Gao and colleagues have identified the molecular mechanism linking a mutation in a complex of proteins to abnormal nervous system development. The team’s findings bring researchers one step closer to understanding neurodevelopmental disorders such as Nicolaides-Baraitser syndrome.
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