Stress creates inflammation
Several studies have linked stress, job strain, and general demoralization to a greater risk for heart disease, though the relationship is less causal than other lifestyle factors, like smoking.
Stress triggers an increase of cortisol, a “stress hormone,” which can raise blood-sugar levels and blood pressure. The overproduction of cortisol can lead to a constant state of chemical arousal, which can eventually cause a heart attack.
One study of Belgian workers found that those who reported feeling they had little control of their work life had increased levels of markers of inflammation such as C-reactive protein and fibrinogen, which are linked to heart disease.