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Abstract: Flow focusing microchannels are widely used in droplet generation mechanisms. In this paper, the effect of linear vibration on the flow pattern in a flow focusing structure and the corresponding formed droplets were numerically investigated using COMSOL Multiphysics® software. The results showed that vibration can be very effective on droplet formation, if the governing parameters such as vibration frequency and flow ratio are chosen accurately. This low-cost technique can be used in a wide range of applications such as drug delivery systems.