Vitiligo - Anogenital in
While the exact etiology is not known, many consider vitiligo to be an autoimmune disease in which the melanocyte is targeted. Genetic predisposition and trauma are other risk factors for vitiligo development. Other autoimmune diseases are observed more frequently in patients with vitiligo, including diabetes mellitus type 1, pernicious anemia, Hashimoto thyroiditis, Graves disease, Addison disease, and alopecia areata.
The segmental form of the disease, which presents as an asymmetric, frequently dermatomal, depigmented band, disproportionally affects children. This form of the disease is less likely to be associated with coexisting autoimmune phenomena.
Vitiligo has been associated with ocular (eg, uveitis) and cochlear abnormalities.
L80 – Vitiligo
56727007 – Vitiligo
- A history of prior trauma or skin inflammation can usually be elicited in cases of post-inflammatory hypopigmentation.
- Albinism, piebaldism, and other genetic disorders – Begin in infancy.
- Morphea – Look for sclerotic plaques.
- Lichen sclerosus – Look for sclerotic plaques, often in the genital area; can be severely pruritic.
- Chemical leukoderma – Look for history of chemical use and/or topical corticosteroids.
Last Updated: 08/11/2017