- remain intact for exceptionally long periods of time (many years);
- become widely distributed throughout the environment as a result of natural processes involving soil, water and, most notably, air;
- accumulate in the fatty tissue of living organisms including humans, and are found at higher concentrations at higher levels in the food chain; and
- are toxic to both humans and wildlife.
As a result of releases to the environment over the past several decades due especially to human activities, POPs are now widely distributed over large regions (including those where POPs have never been used) and, in some cases, they are found around the globe. This extensive contamination of environmental media and living organisms includes many foodstuffs and has resulted in the sustained exposure of many species, including humans, for periods of time that span generations, resulting in both acute and chronic toxic effects.
In addition, POPs concentrate in living organisms through another process called bioaccumulation. Though not soluble in water, POPs are readily absorbed in fatty tissue, where concentrations can become magnified by up to 70,000 times the background levels. Fish, predatory birds, mammals, and humans are high up the food chain and so absorb the greatest concentrations. When they travel, the POPs travel with them. As a result of these two processes, POPs can be found in people and animals living in regions such as the Arctic, thousands of kilometers from any major POPs source.
Specific effects of POPs can include cancer, allergies and hypersensitivity, damage to the central and peripheral nervous systems, reproductive disorders, and disruption of the immune system. Some POPs are also considered to be endocrine disrupters, which, by altering the hormonal system, can damage the reproductive and immune systems of exposed individuals as well as their offspring; they can also have developmental and carcinogenic effects.
IPEN videos on POPs are available in the media section.