Alcohol, in addition to well-known damages on the liver and pancreas, produces direct and
indirect injuries in the mucosa of the oesophagus, stomach, small intestine and large bowel. Different
damages can be produced both when a large amount of alcohol is acutely drunk and when this is taken
chronically. Almost all these lesions can be detected and treated by endoscopy as shown in the present
article. When, over time, cirrhosis ensues the role of endoscopy is not different from that played with
cirrhosis of different etiology. Beside hemorrhagic episodes, esophagitis, gastritis and cancer are the
main alcohol related diseases that can be managed by endoscopy.