Mepivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.
Mepivacaine is used as a local (in only one area) anesthetic for an epidural or spinal block. It is also used as an anesthetic for dental procedures.
Mepivacaine may also be used for other purposes not listed in this medication guide.
Spinal numbing medications can have long-lasting or permanent effects on certain body processes. Talk with your doctor about your specific risk of nerve damage from mepivacaine.
You should not receive mepivacaine if you have ever had an allergic reaction to any type of numbing medicine.
To make sure mepivacaine is safe for you, tell your doctor if you have:
liver or kidney disease;
low or high blood pressure;
heart disease or a history of stroke;
heart rhythm disorder;
coronary artery disease;
epilepsy or other seizure disorder;
a drug allergy; or
if you regularly use any medicines (especially to treat migraine headache, depression, or mental illness).
FDA pregnancy category C. It is not known whether mepivacaine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
It is not known whether mepivacaine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Get emergency medical help if you have any of these signs of an allergic reaction: hives, itching, skin redness; nausea, vomiting, sweating, feeling hot; fast heartbeats; sneezing, difficult breathing; dizziness, fainting; swelling of your face, lips, tongue, or throat.
Tell your caregiver right away if you have:
numbness and tingling in your mouth or lips, metallic taste in your mouth;
ringing in your ears, blurred vision, slurred speech, headache;
confusion, depression, severe drowsiness, feeling like you might pass out;
slow heart rate, weak pulse, weak or shallow breathing;
fever, neck stiffness, increased sensitivity to light;
tremors or muscle twitching, feeling anxious or restless;
ongoing numbness, weakness, or loss of movement in your legs or feet;
loss of bladder or bowel control;
loss of feeling in your lower stomach, groin, or genitals;
painful or difficult urination; or
fast heart rate, rapid breathing, feeling hot.
Common side effects may include:
anxiety, feeling restless or excited;
blurred vision, ringing in your ears.
For an epidural or spinal block, mepivacaine is injected into an area of your lower back near your spine. You will receive this injection in a hospital or surgical setting.
For a dental procedure, mepivacaine is injected into the gum area inside your mouth. You will receive this injection in a dentist's office or oral surgery setting.
Your breathing, blood pressure, oxygen levels, and other vital signs may be watched closely while you are receiving mepivacaine.
Spinal numbing medications can have long-lasting or permanent effects on certain body processes. This includes sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from mepivacaine.
Tell your caregivers right away if you think you have received too much of this medicine.
Overdose symptoms may include extreme drowsiness, seizure (convulsions), shallow breathing, or slow heart rate.
Since mepivacaine is given as needed before a surgery or other medical procedure, you are not likely to be on a dosing schedule.
Reactions resulting in fatality have occurred on rare occasions with the use of local anesthetics, even in the absence of a history of hypersensitivity.
Fatalities may occur with use of local anesthetics in the head and neck region as the result of retrograde arterial flow to vital CNS areas even when maximum recommended doses are observed. The practitioner should be alert to early evidence of alteration in sensorium or vital signs.
The solution which contains a vasoconstrictor (Mepivacaine HCl 2%) should be used with extreme caution for patients whose medical history and physical evaluation suggest the existence of hypertension, arteriosclerotic heart disease, cerebral vascular insufficiency, heart block, thyrotoxicosis and diabetes, etc.
The solution which contains a vasoconstrictor (Mepivacaine HCl 2%) also contains potassium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in non-asthmatic people. Mepivacaine HCl 3% is SULFITE FREE.
Mepivacaine, along with other local anesthetics, is capable of producing methemoglobinemia. The clinical signs of methemoglobinemia are cyanosis of the nail beds and lips, fatigue and weakness. If methemoglobinemia does not respond to administration of oxygen, administration of methylene blue intravenously 1-2 mg/kg body weight over a 5 minute period is recommended.
The American Heart Association has made the following recommendations regarding the use of local anesthetics with vasoconstrictors in patients with ischemic heart disease: "Vasoconstrictor agents should be used in local anesthesia solutions during dental practice only when it is clear that the procedure will be shortened or the analgesia rendered more profound. When a vasoconstrictor is indicated, extreme care should be taken to avoid intravascular injection. The minimum possible amount of vasoconstrictor should be used.
1) Quality Standard: USP 35
2) Purity: >99%
3) We are manufacturer and can provide high quality products with factory price.
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
1)Safe delivery: Channel diversification,protect the privacy of customers.And just in case, ensure to re-ship.
2)Never change: The product will always maintain high purity, will not change,High quality is the culture of our company.
3)Good services: As quickly as possible to solve customer problems, so that customers receive the goods safely.