Metabolism of Lipids in Advanced Cancer
Weight loss in cancer is the result of breakdown of fat (lipid) and muscle protein reserves.
This research will explore how people with cancer use fat in their body through the use of
tracers and measures in the blood. A stable isotope of hydrogen called 'deuterium' is used
to trace the production of different fats by the liver. Other methods will determine how
much and what types of fat are transported around the body. Body composition will be
determined by CT scan and related to fat measures.
Observational Model: Case-Only, Time Perspective: Cross-Sectional
Rate of hepatic de novo lipogenesis
Vera Mazurak, PhD
Alberta Health Services
Canada: Health Canada
CIHR PIN 111846/ethics 24906