Using DNA microarrays to study cancer, Patrick Brown
Interviewee: Pat Brown.
Pat Brown talks about using microarrays to discover the differences between cancer cells and healthy cells.
(DNAi Location: Applications > Genes and medicine > genetic profiling > Patrick Brown > Using microarrays to study cancer)
Well we knew that differences in the gene expression program were largely responsible for the differences in the appearance and the behavior of the normal cells in our body, say a brain cell compared to a liver cell. And so it seemed natural that by looking systematically at the gene expression program in cancer cells, we would be able to get a better understanding of why those cells are different from their normal counterpart and why a breast cancer in one woman looks and behaves differently from a breast cancer in another woman.