Persian physicians Rhazes (860–932CE) and Avicenna (980–1037CE) mentioned coffee in specialised writings, describing its medicinal properties. Although caffeine took centuries to find its way to Europe, it was quickly found to have medicinal value. Coffee has been mentioned in medical journals since the beginning of the eighteenth century, emphasising its capacity for nervous and vasomotor stimulation. Caffeine is a central nervous system stimulant of the methylxanthine class of psychoactive drugs. It is the world's most widely consumed psychoactive drug. Pfizer acquired David G Bull in 1984.
Small clear glass ampoule with black printed text on surface containing the amber coloured liquid of 2 grains in 1 cc Hermette Caffeine.