Michigan Team Singles Out Cancer Stem Cells for Attack
Close on the heels of the discovery that cancer has its own rejuvenating stem cells, a University of Michigan research team has found a way to distinguish these bad-actors from the normal stem cells that they so closely resemble, and to kill the cancer stem cells without harming the normal stem cells in the same tissue.
Lab Grows Bladders From Cells of Patients
It is the first time a complex human organ like the bladder has been mostly replaced with tissue grown from a patient’s own cells.
Broken Bone Treatment First
A Melbourne hospital is using cultured adult stem cells to heal broken bones in a clinical trial.
Bone Loss Seen in Children After Stem Cell Therapy
A type of stem cell therapy called hematopoietic cell transplantation (HCT) often leads to a reduction in bone formation in children, according to Minneapolis-based researchers.
New Applications for Cord Lining Stem Cells – Diabetes and Wound Healing
Cord Lining Stem Cells discovered by CellResearch Corporation makes headway in areas with exciting potential therapeutic applications
Gene Therapy Helps Blind Mice See the Light
A protein normally found in green algae can make retinal cells in blind mice sensitive to light, researchers report, adding that advances with the technique could one day help restore sight in people with inherited eye problems.
Article 1 Article 2
Umbilical Cord Blood: The Future of Stem Cell Research?
Researchers at the University of Minnesota recently announced that they were able to largely reverse the effects of stroke in lab rats using stem cells found in human umbilical cord blood.
Results In For First Gene Therapy For Alzheimer’s Disease
Researchers say they see promising results from the first gene therapy trial for Alzheimer’s disease. And one of the trial’s patients believes the experimental treatment slowed down her disease.
Researchers Explore New Technique to Treat High Blood Pressure, Kidney Damage
Using a corrective gene, scientists were able to block a protein in the kidneys that triggers high blood pressure and kidney damage.
Stem Cell Transplants Improve Recovery In Animal Models For Stroke, Cerebral Palsy
A single dose of adult donor stem cells given to animals that have neurological damage similar to that experienced by adults with a stroke or newborns with cerebral palsy can significantly enhance recovery from these types of injuries, researchers say.
Factor Stimulates Cartilage Growth from Stem Cells
A novel growth factor significantly improves the ability of specialized stem cells derived from human fat to be transformed into cartilage cells, according to Duke University Medical Center and Pratt School of Engineering researchers.
Israeli Researchers Regenerate Torn Ligaments and Tendons with Adult Stem Cells
In studies conducted on rats, the researchers at the Skeletal Biotechnology Laboratory at the university’s Faculty of Dental Medicine have successfully used adult stem cells to form new tendon or ligament tissue.
Virginia Commonwealth University’s Medical CenterTeam Implants Total Artificial Heart
The cardiac surgery team at Virginia Commonwealth University’s Pauley Heart Center has performed the first artificial heart implant on the East Coast.
AVEO Presents a Novel System for the Generation of Fully Human Breast Tumors in Mice
AVEO Pharmaceuticals, Inc., a biopharmaceutical company focused on the discovery and development of novel cancer medicines, announced today that is has developed the first system which allows for the generation of fully human breast tumors in mice.
Mutation in Blood Stem Cells Provides Clues to Cancer Development
A mutation in blood stem cells occurs in patients with a blood disorder called polycythemia vera (PV), scientists at the Moores Cancer Center at the University of California, San Diego (UCSD) and the Institute for Stem Cell Biology and Regenerative Medicine and Comprehensive Cancer Center at Stanford University School of Medicine have confirmed.
The Immune Response Corporation’s MS vaccine Spurs T-cell Response
The Immune Response Corporation announced that its T-cell receptor peptide vaccine candidate, NeuroVax(TM), induces increased FOXP3 expression resulting in re-establishment of normal levels of the FOXP3+ regulatory T-cells believed to be important in controlling the development of multiple sclerosis (MS).
Co-Researcher of Hwang Faked Stem Cells Alone
Prosecutors have tentatively concluded that Kim Sun-jong, co-researcher of disgraced cloning expert Hwang Woo-suk, fabricated samples of stem cell lines without Hwang’s knowledge.
Pair Indicted For Fake Stem Cell Therapy
A federal grand jury in Atlanta has returned an 51-count indictment against Laura Brown, 35, of Miami Beach, Florida, and Stephen Van Rooyen, 44, of Cape Town, South Africa, on charges of wire fraud and distributing unapproved and misbranded drugs relating to fraudulent claims of stem cell treatment and therapy.
ABSTRACTS, REVIEWS & SPECIAL REPORTS
The Long Journey from Stem Cells to Medical Product
There is much interest in developing stem cells and the cells derived from them as therapies for treating human disease and injury, but many biological, technological and regulatory hurdles have to be overcome before these cell therapies can be brought to commercial fruition.
Correction of X-linked Chronic Granulomatous Disease by Gene Therapy, Augmented by Insertional Activation of MDS1-EVI1, PRDM16 or SETBP1
The results suggest that gene therapy in combination with bone marrow conditioning can be successfully used to treat inherited diseases affecting the myeloid compartment such as Chronic Granulomatous Disease.
Pten Dependence Distinguishes Haematopoietic Stem Cells from Leukaemia-Initiating Cells
Mechanistic differences between normal stem cells and cancer stem cells can be targeted to deplete cancer stem cells without damaging normal stem cells.