Known as the infamous skylab mutiny, it was a day-long strike by Skylab 4 that happened on December 28, 1973. This actually marked the last of the Skylab missions that were run by NASA and it had a three-man crew.
Gerald Carr, Edward Gibson, and William Poque formed up the crew and on that day they decided to turn off all communications with NASA ground control. The reason? They felt overworked, so they took a day off and spent it relaxing. They reportedly just spent the day looking at Earth and then resumed communications with NASA. As per a mutiny, they refused to talk to NASA for the whole period, and then afterward discussed how to move forward.
As the mission had several more weeks left before returning to Earth. This mission was actually 84 days the longest mission of the Skylab era, and it marked a change in NASA onlook on space missions as it took two whole decades before an American astronaut set foot in another space station.
It is an event that has been looked into repeatedly, as it is the only ever known team of astronauts that have gone on strike. A case which has been studied carefully to find out the perfect balance which is needed to endeavor space missions. This includes things like food, relaxation, team management, and even psychology. When it comes to sending people into space it becomes an extremely expensive project, so governments tend to want to ensure their money is well spent.
For example, a single day in Skylab was worth about $22.4 million dollars, so you can only imagine how seriously NASA took this strike at the time. And has continued to ensure its mission look at every aspect of an astronauts time in space, to ensure future projects like going to Mars or returning to the Moon will be a success.