Aerobic Exercise Important Therapy for Preventing, Slowing Down Dementia
Mayo Clinic: ‘very compelling argument for exercise as a disease-modifying strategy to prevent dementia and mild
Sept. 7, 2011 - Any exercise that gets the heart pumping may reduce the risk of dementia and slow the condition's
progression once it starts, reported a Mayo Clinic study published this month in Mayo Clinic Proceedings.
Researchers examined the role of aerobic exercise in preserving cognitive abilities and concluded that it should not be
overlooked as an important therapy against dementia.
The researchers broadly defined exercise as enough aerobic physical activity to raise the heart rate and increase the
body's need for oxygen. Examples include walking, gym workouts and activities at home such as shoveling snow or raking leaves.
"We culled through all the scientific literature we could find on the subject of exercise and cognition, including animal
studies and observational studies, reviewing over 1,600 papers, with 130 bearing directly on this issue. We attempted to put together a
balanced view of the subject," says J. Eric Ahlskog, M.D., Ph.D., a neurologist at Mayo Clinic.
"We concluded that you can make a very compelling argument for exercise as a disease-modifying strategy to prevent
dementia and mild cognitive impairment, and for favorably modifying these processes once they have developed."
The researchers note that brain imaging studies have consistently revealed objective evidence of favorable effects of
exercise on human brain integrity. Also, they note, animal research has shown that exercise generates trophic factors that improve brain
functioning, plus exercise facilitates brain connections (neuroplasticity).
More research is needed on the relationship between exercise and cognitive function, the study's authors say, but they
encourage exercise, in general, especially for those with or worried about cognitive issues.
"Whether addressing our patients in primary care or neurology clinics, we should continue to encourage exercise for not
only general health, but also cognitive health," Dr. Ahlskog says.
Co-authors of the study include Yonas Geda, M.D.; Neill Graff-Radford, M.D.; and Ronald Petersen, Ph.D., M.D.
About Mayo Clinic
Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life.
For more information, visit www.mayoclinic.com.
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