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Anti Estrogens block the effects of the sex hormone estrogen, a natural steroid hormone, mainly responsible for the regulation of the female reproductive cycle. Lowering the level of estrogen through aromatase inhibitors and blocking the effect of estrogen with anti-estrogenic compounds is required to correct the estrogen dominance syndrome, a kind of imbalance of sex hormones. Aromatase inhibitors act by blocking the production of estrogen from androgens in postmenopausal women and men. Antiestrogenic compounds bind to estrogen receptors in cells, preventing the activation of these receptors by estrogen.
It is believed that the development of the syndrome of estrogen dominance is promoted by food sources of plant estrogens and chemical anti estrogens substances simulating this hormone in the external environment. So, to cause hormonal imbalance can be excessive consumption of meat and dairy products derived from animals that have been treated with hormones. Some plants and herbs, including soy, are sources of non-steroid plant estrogens, which can also increase the level of estrogen.
Estrogens and anti-estrogens in nature
In the environment, chemicals are widely distributed that act as estrogens. Their sources are plastics, agricultural chemicals, cosmetics and household chemicals. Antiestrogens are thought to neutralize the effects of excessive exposure to estrogen from food and external sources. Too much estrogen is associated with
- atherosclerosis in elderly women,
- early onset of puberty in children,
- development of hormone sensitive types of cancer.
Excess estrogen can also be responsible for increasing the level of obesity. It is believed that the syndrome of estrogen dominance causes the development of many chronic diseases, including a decrease in male fertility. To counterbalance the effects of excess estrogen, anti-estrogens are used.
In some countries, anti-estrogenic substances are available by prescription, while in others they are sold as non-prescription dietary supplements. In certain localities, there are forms of these funds for both prescription and non-prescription leave. Bodybuilders often use anti-estrogen supplements and aromatase inhibitors to accelerate muscle development and reduce the side effects of steroids. Tamoxifen is a anti estrogens prescription anti-estrogen remedy used to treat estrogen-sensitive breast cancer in premenopausal women. It binds to the estrogen receptors of cancer cells without activating them.
For the treatment of postmenopausal women with estrogen-sensitive breast cancer, aromatase inhibitors are used. It is believed that breast cancer uses for growth of estrogen in 80% of cases. In postmenopausal women, estrogen is produced from androgen in fat tissues, including the breast. By suppressing the production of estrogen, it is possible to reduce the amount in which it enters the cancer cells.
With estrogen dominance syndrome, you can also cope with a change in diet. It is necessary to avoid specific foods rich in estrogen, giving preference to products that are antagonists of estrogen. The anti estrogenic diet excludes meat and dairy products produced in a standard way, as well as fruits and vegetables with a high residual amount of pesticides. It is recommended the use of organic products, including fresh vegetables and fruits, and products of animal anti estrogens origin. Among products that have a pronounced antiestrogenic effect, include champignons, cruciferous vegetables and green tea.
Anti Estrogens: how to take?
Dosage is selected strictly individually, on average, 50-100 mg per day is recommended. The dose is selected depending on the specific drug. When taking medicines, never exceed the dose indicated on the package.
Before you start taking estrogens – consult a doctor: he will prescribe the right dosage and will give the necessary recommendations for a lifestyle, training while taking medications, help anti estrogensto avoid “pobochki.”
Any hormonal drugs carry a certain risk in the form of undesirable consequences in the impact on the body: correcting one, not the best way influencing the other. In case of taking antiestrogens, it is possible:
- the appearance of joint pain;
- decreased libido;
- dizziness, nausea;
- depressive conditions;
- thinning hair, etc.
In rare cases, confusion, dyspnea, severe cough, thromboembolism, and some other side effects may occur. Therefore, consultation and medical anti estrogens supervision during the administration of antiestrogens are mandatory.