Recent clinical trials have demonstrated that T cells can be extracted from a patient, reprogrammed to attack leukemia cells, and then injected back into the patient to eradicate the target cells (e.g. B cells). Our research aims to increase the efficiency of this process by optimizing the delivery and expression of foreign genes in T cells using CRISPR/Cas9-mediated genome editing.
Drug Discovery and Development Laboratory
Led by Director Jacob Elmer, the Drug Discovery and Development Lab is focused on research in these areas:
Development of Earthworm Hemoglobin as an Ultra-Stable Blood Substitute
Engineering Education Research
We have designed a set of inexpensive 3D-printed Arduino-driven sensors and devices that can be used in the lab to take routine measurements or implemented as a class project to teach students about CAD software, additive manufacturing, and basic circuitry/coding.