Under normal conditions, ultraviolet (UV) radiation from the sun activates melanocytes to release melanin, a pigment that protects the skin from the sun's rays. Deletion of Hgma2 gene in mutated melanocyte stem cells can prevent chances of occurrence or development of melanoma after UV radiation found a new study published in Cell Stem Cell journal. Cornell researchers have discovered that when melanocyte stem cells accumulate a sufficient number of genetic mutations, they can become the cells where these cancers originate.
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