In childhood, a disorder which involves both the heart and lungs problems, called Pediatric Cardiopulmonary disease. Epicardial adipose tissue (EAT) is the visceral fat deposit around the heart and is commonly increased in obese subjects. EAT is related to Cardio Metabolic risk factors and non-alcoholic fatty liver disease (NAFLD) in adults, but this relationship is not well known in children. (MI) Myocardial infarction is rare in childhood and adolescence. Children usually have either an acute inflammatory condition of the coronary arteries diseases or an anomalous origin of the left coronary artery (LCA). Peripheral vascular diseases (PVDs) are circulation disorders that affect blood vessels outside of the heart and brain. In PVD, blood vessels are narrowed. Narrowing is usually caused by arteriosclerosis. We will be discussed more about the common problem of the baby heart diseases as Cardiomyopathy, Myocarditis, Hypoplastic Left Heart Syndrome, Hypertension, Heart Murmur, Cardiac Arrest, Pericarditis Effusion, Arrhythmogenic Right Ventricular Dysplasia, Cyanotic Heart Disease, and Pediatric Arrhythmia.