Scientists have uncovered the bizarre extra sense which goes beyond taste, smell, touch, sight and hearing.
The sixth sense is often associated with humans' perception of spirits and ghosts – popularised by the Bruce Willis film of the same name.
In the movie a young child is haunted by visitations of spirits in the shadows thanks to his sixth sense power.
But the latest discovery by a researchers in America reveals humanities extra sense is actually nothing to do with being able to see dead people.
“Piezo2 is a touch and proprioception gene in humans”Carsten Bonnemann
American scientists discovered the "intuition gene" which affects our body awareness – allowing us to tell where our limbs are without having to see them.
The discovery was made by research on two patients with a rare genetic disorder which meant they were unable to walk without falling while blindfolded.
They could not track the position of their arms and legs while researchers moved them – which most people can do instinctively.
The research into their mutation in the gene called Piezo2 confirmed the existence of the sixth sense.
Neurologist Dr Carsten Bonnemann, of the National Institutes of Health in Maryland, US, said: "Our study highlights the critical importance of Piezo2 and the senses it controls in our daily lives.
"The results establish Piezo2 is a touch and proprioception gene in humans.
"Understanding its role in these senses may provide clues to a variety of neurological disorders."
The study was published in the New England Journal of Medicine.
Co-author Dr Alexander Chesler said: "As someone who studies Piezo2 in mice working with these patients was humbling.
"Our results suggest they are touch-blind. The patient's version of Piezo2 may not work so their neurons cannot detect touch or limb movements."
Last week scientists revealed the world's first genetically engineered "three parent" child.