In retinal disease, sight may depend on second sites
... all? For a group of genetic diseases so-called ciliary
diseases that include Bardet-Biedl syndrome, ... of progressive blindness in patients with other ciliary
diseases. The findings are published online this ... they affect disease progression. In the case of ciliary
diseases where there is a risk of retinal ...
Eye Cells Believed to Be Retinal Stem Cells Are Misidentified
... in 2000, scientists proposed that the layer of ciliary
epithelial cells lining the inside of the eye, ... revealed all were pigmented and had features of ciliary
epithelial cells. The researchers also compared ... characteristic of stem cells, yet remain adult ciliary
Dyer said that a ...
The Power of a Tiny Microscopic Plant Found To Reduce Computer Eye Strain
... including such things as increased capillary blood flow and improved ciliary
body function. The ciliary
body is a small muscle in the eye responsible for controlling the lens of ...
JCI table of contents: Nov. 21, 2007
... location: gene determining body organ position identified
diskinesia (PCD) is an inherited disease caused by mutations in any one of ... and complex structural heart defects in a mutant mouse model of primary ciliary
Cecilia W. Lo
National Institutes of ...
The Reduction of Eye Fatigue Improves Vision in Older Subjects
... activated functions of three muscles in the eye; the constrictor pupillae muscle and dilator pupillae muscle working in coordination with the ciliary
muscle. Astaxanthin has been shown in other studies to improve muscle endurance and recovery.
Although the basic measure for presbyopia is ...
Misuse of Vicks VapoRub may harm infants and toddlers
... airways and 8 percent in the inflamed airway, in addition to the increase in secretion due to the inflammation. Mucus clearance, as measured by ciliary
beat frequency in the trachea, also decreased by 36 percent during in vitro testing.
VVR is not indicated for patients under age 2. However, Dr. ...
St. Jude finds 'dancing' hair cells are key to humans' acute hearing
... we still cannot really exclude stereociliary motility from contributing to cochlear amplification, because eliminating somatic motility also reduces ciliary
motility. So, it is not possible to totally isolate either form of motility. In fact, we hypothesize that the two mechanisms might work together in ...
When poor communication pokes you in the eye
... phase. The same applies also to the formation in healthy eyes of elastic and transparent lenses, which focus light beams. With the aid of the ciliary
muscles, the lens can change its degree of curvature and thus set itself on varied, far distant objects. As a result, a pin sharp image is created on ...
Some Immature Brain Cells May Promote Tumors
... from people with glioblastoma multiforme to develop a cell that ignored the effects of two proteins -- bone morphogenetic protein-2 (BMP2) and ciliary
neurotrophic factor (CNTF) -- that usually cause brain stem cells to grow. Instead, the cells partially responded to one protein (BMP2) and not the ...
Neurotech Announces Completion of Enrollment of its Phase II/III Retinitis Pigmentosa and Phase II Dry Age Related Macular Degeneration Clinical Studies
... AMD). NT-501 is an intraocular, cell containing
polymer implant designed to provide the continuous, long-term release of
the therapeutic protein, ciliary
Neurotrophic Factor (CNTF), directly into
the back of the eye by means of the Company's proprietary Encapsulated Cell
Technology (ECT). "This is a ...
Newborns With Respiratory Distress Potentially Have Rare Genetic Disease
... distress should be evaluated for primary ciliary
dyskinesia, a rare genetic disease that has ... that about 80 percent of patients with primary ciliary
dyskinesia (PCD) have a history of newborn ...
Also known as immotile cilia syndrome, ciliary
aplasia or Kartagener Syndrome, PCD causes ...
Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum
... polycystins, which are mechano-receptors in the ciliary
membrane. Through a signaling pathway, the ... to defects in receptors or channels on the ciliary
membrane, or to the complete lack of the cilium ... causing the cilia to shorten, and permitting the ciliary
basal bodies/centrioles to migrate to the center ...
Loss of Antenna Leads to Cancer in Insects
... Cell, Fox Chase Cancer Center researchers describe the strong link between ciliary
signaling and cancer and identify the rogue engineers responsible for ... or PKD, arises from genetic mutations that cause flawed kidney-cell ciliary
signaling. PKD is the most common serious hereditary disease, affecting ...
'Oncomodulin'- Path To Nerve Regeneration
... a sugar mannose and forskolin which helps the cell receptors to become sensitised to protein messengers and this combination was more potent than ciliary
neurotrophic factor CNTF in the same conditions.
Oncomodulin has been known to scientists for more than two decades to be present ...
A Protein May Help In Weight Loss Treatment
... acts directly within muscles to increase the body's metabolism to burn fat while at the same time suppressing appetite. The protein is knows as the ciliary
neurotrophic factor (CNTF). The Heart and Stroke Foundation of Canada, the Canadian Institutes of Health Research, and the Canadian Diabetes ...