Faster to result
Inhibitor-free nucleic acids
Superior for challenging samples
Reduced consumable costs
Fewer toxic reagents
Extracting DNA from animal sample types or plant cells often results in an unfavorable gDNA yield and purity for downstream applications. Differences in cell numbers for blood between animal species lead to a reduced yield. In plants, rigid cell walls must be lysed appropriately in order to expose the cytoplasm. Native DNA contaminants affect the quality of isolated DNA and can inhibit downstream enzymatic reactions.
Our EchoLUTION extraction technology involves a lysis step that is tailored to animal or plant sample types allowing for an efficient lysis and purification to avoid carryover of contaminants.
Particularly in experiments, where sensitivity is of high importance (such as qPCR with limited sample material), EchoLUTION-purified DNA outperforms results obtained with the silica-based technology.
- Up to fivefold more DNA yield than with silica-based kits
- No native DNA contaminants
- No toxic substances or chaotropic salts that inhibit downstream applications
Tedious bind–wash–elute procedures build a bottleneck in daily routines. Our EchoLUTION technology relies on single-step nucleic acid isolation within a one-minute centrifugation. Nucleic acids pass through the purification matrix without interaction, while impurities are held back and are completely removed. Different from the conventional silica-based bind–wash–elute nucleic acid extraction methods, EchoLUTION allows today’s fastest and simplest nucleic acid extraction with the highest purity.
“We used the BioEcho EchoLUTION Tissue DNA and Cell Culture DNA kits for extraction of genomic DNA from cultured cells and from fresh and stabilized human tissue. Both kits impressed with their simplicity, speed, and with stable and reproducible yields. Purified DNA could immediately be used for downstream applications, such as PCR.”
Department of Biotechnology, TU Braunschweig
“We are using BioEcho’s Tissue DNA Micro kit successfully and on a regular basis for DNA isolation from fish tissue samples.”
University of Edinburgh
“We compared the EchoLUTION Plant DNA Kit with our established silica-technology based kit. Using the BioEcho kit we obtained genomic DNA in high yields much faster and easier than before. We were impressed about the simplicity of the whole process.”
Dr. Yang Yi,
Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Sciences
“We at Advanced Identification Methods (AIM) are specialized in the analyses of the biodiversity of our environment using genomic methods. For example, we analyze bulk samples derived from insect traps and mixed plant, wood, and soil samples by extracting the total DNA from the biological samples and a subsequent identification of individuals present by DNA metabarcoding. We have thoroughly tested the EchoLUTION DNA extractions kits for animal tissue and plant materials and use these very successfully in our routine workflows. Besides the technical reliability of the kits, we like the sustainability approach of BioEcho a lot. Using their kits, we save a lot of plastic waste and don’t have any hazardous liquid waste anymore!”
CEO, Advanced Identification Methods – AIM GmbH, Leipzig, Germany
Get more input about nucleic acid extraction in academic research
DNA extraction from mammalian cells
Researchers from TU Braunschweig extracted total DNA from a wide range of mammalian cell preparations and tissues.
gDNA extraction from embryonic stem cells
Researchers at the University Bonn investigated an inducible overexpression system in mouse embryonic stem cells. The EchoLUTION Cell Culture Kit was used to extract the genomic DNA, which was used to determine copy number by qPCR.
Barley gDNA extraction for genotyping
Scientists from Spain and Hungary researched the responses of barley to high ambient temperatures. The BioEcho Plant DNA Kit was used for genomic DNA extraction for amplifications, KASP assays, and whole-genome genotyping.
Bee gDNA extraction for NGS
Husemann et al. researched the mitogenomic phylogeny of bee families. The DNA extraction was performed with the EchoLUTION Blood DNA HiYield Kit for NGS-library preparation.
Guppy gDNA extraction for microsatellite genotyping
Charlesworth et al. researched the evolution of the guppy Y chromosome. The authors used the EchoLUTION Tissue DNA Kit to extract gDNA for microsatellite genotyping.