In humans, cell differentiation does not involve changes in the base sequence or in the amount of DNA, with few exceptions. Rather, ‘epigenetic’ mechanisms are employed to establish stable patterns of gene expression. In this case, ‘epigenetic’ mechanisms are those which establish stably inherited patterns of gene expression in somatic cells without changes in the content or sequence of genomic DNA.
KeywordsGerm Cell Epigenetic Mechanism Imprint Gene Primordial Germ Cell Stem Cell Phenotype
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