Fever of Unknown Origin
(FUO; Pyrexia of Unknown Origin)
- A common illness that does not have the usual symptoms
- Illness, whose other symptoms appear later
- Illnesses who may have a delayed positive test
- Person is unable to communicate about other symptoms such as an infant or someone in a coma
- Genetic condition that causes periodic fevers—very rare
- Were you traveling abroad?
- Were you hospitalized?
- Is your immune system damaged?
- What medicines are you currently taking?
- Blood, urine, and other body products testing
- Images of internal organs and structures with x-rays , CT scans, MRI scans, or ultrasound
- Biopsy of suspicious tissue
- Endoscopies to examine the inside of the lungs, intestines, or sinuses
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American Academy of Family Physicians http://familydoctor.org
American Academy of Pediatrics http://www.healthychildren.org
Caring for Kids http://www.caringforkids.cps.ca
Health Canada http://www.hc-sc.gc.ca
Roth A, Basello G. Approach to Adult Patient with Fever of Unknown Origin. Am Fam Physician. 2003 Dec 1;68(11):2223. Available at: http://www.aafp.org/afp/2003/1201/p2223.html. Accessed May 20, 2013.
Fever of Unknown Origin (FUO). EBSCO DynaMed website. Available at: http://www.ebscohost.com/dynamed/what.php . Updated November 13, 2012. Accessed May 20, 2013.
Gelfand JA, Callahan MV. Fever of unknown origin. In: Kasper DL, Braunwald E, Fauci A, Hauser S, Longo D, Jameson JL. Harrison's Principles of Internal Medicine . 16th ed. New York: McGraw-Hill; 2005: 16-121.
Goldman L, Ausiello D, eds. Cecil Textbook of Internal Medicine. 23rd ed. Philadelphia, PA: Saunders; 2008.
- Reviewer: Michael Woods, MD
- Review Date: 05/2013
- Update Date: 07/00/2013