Friday 21 November 2003
Not all nucleotide changes produce genes that cause disease. When such a DNA change occurs in at least 1% of the population, it is called a polymorphism. SNPs is the most common form of polymorphism.
Population genetics: SNPs that come in threes. Casci T. Nat Rev Genet. 2010 Jan;11(1):8. PMID: 20050277
Payseur BA, Cutter AD. Integrating patterns of polymorphism at SNPs and STRs. Trends Genet. 2006 Aug;22(8):424-9. PMID: 16806567
Wakeley J, Nielsen R, Liu-Cordero SN, Ardlie K. The discovery of single-nucleotide polymorphisms—and inferences about human demographic history. Am J Hum Genet. 2001 Dec;69(6):1332-47. PMID: 11704929