Using Hyaluronic Acid in the treatment of inflammatory situations is a well-known and well-established practice in several medical branches, such as orthopaedics, dermatology and ophthalmology. When it comes to dentistry, Hyaluronans have shown anti-inflammatory and anti-bacterial properties in the context of gingivitis and periodontitis therapies.
Periodontitis, commonly known as gum disease, is a severe gingival infection that affects the soft tissue and, if untreated, may destroy the bone that supports the tooth. It is the most common cause of tooth loosening and tooth extraction episodes, and it may concern all age ranges of the population.
Usual treatment of such condition always begins with correct and rigorous implementation of oral hygiene best practices. However, in the most complicated cases, periodontal surgery and consequent chemical treatment are necessary to achieve a good recovery. In such eventuality, surgery is needed to access to the pocket area and carry out a due debridement, removing the pathological tissue and reconstructing bone, enamel, ligament and gingiva.
Researches established that HA tissue-healing properties can support the mechanical therapy, making it more effective and speeding up the recovery process: it is in fact a key component of periodontal ligament matrix, covering a plethora of functions essential to keep such ligament in good health during this delicate phase. To begin with, Hyaluronans play a paramount role in post-inflammatory wound-healing, supporting and accelerating cell migration and differentiation during the formation of new tissues. In addition, the unparalleled hygroscopic capacity of HA allows the gingiva tissue to absorb water and using it to expand the extracellular space and exert a cushioning action to the bite force on the interested periodontal ligament. Finally, high-MW Hyaluronans such as our SinoHyal FG-XH even exert a bacteriostatic effect, reducing bacterial adhesion capacity and thus biofilm formation.
While final success rate of the whole treatment and overall mouth health are always upon long-term maintenance of a good oral hygiene, Hyaluronic Acid turns emerges as a valid ally in contrasting one of the most common dentistry conditions in the world.