The Eastern Band of Cherokee Indians (EBCI), or Tsalagiyi Detsadanilvgi is a federally recognized Native American tribe in the United States of America, who are descended from Cherokee who remained in the Eastern United States while others moved, or were forced to relocate, to the west in the 19th century. The history of the Eastern Band closely follows that of the Qualla Boundary. The EBCI also own, hold, or maintain additional lands in the vicinity, and as far away as 100 miles from the Qualla Boundary. The Eastern Band of Cherokee Indians are primarily the descendants of those persons listed on the Baker Rolls of Cherokee Indians.
The Eastern Band of Cherokee Indians is one of three federally recognized Cherokee tribes, the others being the Cherokee Nation and the United Keetoowah Band of Cherokee Indians, both in Oklahoma.