Neuropathic pain is a chronic condition of a heterogeneous nature and has different causes. Different and more onerous than nociceptive pain, neuropathic pain more severely affects people's quality of life. Understanding the various mechanisms of the onset and progression of neuropathic pain is important in the development of effective treatment. Research is underway to replace current drug treatments with cell therapies that will have longer lasting effects.
Stem cells present interesting potential therapy for neuropathic pain. In this review, we describe the neuroprotective effects of stem cells along with a special emphasis on current translational research that uses stem cells to treat neuropathic pain. Stem cells are rapidly becoming a viable treatment option for patients with neuropathy. Nerve damage can be treated with stem cell therapy.
Stem cells are usually injected into the problem area where the nerves are most damaged. This way, stem cells can repair nerves in that area. At Regenesis Stem Cell Center, Dr. Charles Lee Offers Comprehensive Stem Cell Approach to Neuropathy Using State-of-the-Art Technology.
Neuropathy is a common disorder caused by damage to nerves outside the brain and spinal cord, known as peripheral nerves. These nerves can be damaged as they leave the spinal canal or even reach the smallest nerve fibers in the skin. The condition may cause pain, numbness, or weakness, especially in the hands and feet, and is difficult to treat. Our patients choose stem cell therapy for neuropathy at Regenesis Stem Cell Center because they want an effective, low-risk, non-surgical option that can help them heal and prevent further nerve damage.
It should be noted that some patients suffering from neuropathy have been deceived by fraudulent stem cell centers. In recent years, stem cell therapy has shown enough promise to ensure an important position in the field of translational medicine. MSC stem cell treatments focus on the root of the underlying problem (nerve damage), not just temporarily masking symptoms with pain relievers. Stem cells reduce spinal cord apoptosis and promote recovery of injured nerves, which play an important role in analgesia and treatment of NP.
As a person looking to treat stem cell neuropathy, you should be aware of stem cell treatment centers that won't help your condition. If the bad news is that there are so many potential causes of neuropathy, the good news is that stem cell treatments have the potential to address them all. When bone marrow stem cells (BMSCs) were co-cultured with ischemic injured tissue (where BMSCs were not in direct contact with ischemic tissue), the neuroprotective effects provided by BMSCs were found to be equal to the effects of direct transplantation on injured tissue. The results of this study indicated increased production of neurotrophic factors in HuC-MSC stem cells compared to bone marrow-derived stem cells; however, both cell types had measurable amounts of neurotrophic factors secreted.
In these cases, stem cell therapy may help treat symptoms and protect against ongoing damage, but it cannot treat the underlying cause. As shown in Figure 1, stem cells also play an anti-inflammatory role through the mitogen-activated protein kinase (MAPK) pathway. In other words, while there are strong scientific reasons to be excited about the potential of stem cells to treat nerve damage, it is still too early to promise their effectiveness in all cases. Stem cells not only promote recovery from peripheral nerve injury, but also play the same role in the central nervous system.
In addition, because these stem cells replicate indefinitely, they will offer these benefits for the rest of the patient's life. The Stem Cells Transplant Institute recommends the use of HuC-MSC for the treatment of diabetic neuropathy. Researchers participate in clinical treatments for spinal cord repair, nerve cell regrowth from trauma, neuroregeneration for stroke patients, and repair of peripheral nerve damage caused by diabetes. If you have pain, numbness, or tingling in your hands or feet, or if you have been diagnosed with neuropathy and traditional treatments do not provide relief, you could benefit from stem cell therapy for neuropathy.