Enzyme inhibitor = substance that directly or indirectly interferes with functioning of active site of enzyme - reducing activity.
- Competitive inhibitor - binds to active site of enzyme.
- Non-competitive inhibitor - binds to enzyme at position other than active site.
Have molecular shape similar to substrate.
Can occupy active site of enzyme and compete with substrate.
Difference between concentration of inhibitor and concentration of the substrate = affect inhibitor has on enzyme activity.
Competitive slows action because eventually all substrate will occupy an active site.
Effect is decreased by increasing substrate concentration.
Attach themselves to enzyme at a site other than active…