CHANGES in the amount of blood being delivered to different brain areas may be one of the earliest factors associated with late-onset Alzheimer's disease.
A paper published in Nature Communications says Yasser Iturria Medina and colleagues compared brain imaging data, blood plasma and cerebral spinal fluid samples from a database comprising 1171 healthy and disease-affected individuals.
These results show a correlation between changes in blood flow and disease progression, but further studies are required.
The idea that blood flow disruptions may contribute to Alzheimer's disease has been around since the early 1900s.
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