Chromatography is the collective term for a set of laboratory techniques for the separation of mixtures. Chromatography has many uses. It is commonly used in laboratories to isolate new compounds, analyze subtle differences between different environmental samples, and even in the sequencing of DNA. In any chemical or bioprocessing industry, the need to separate and purify a product from a complex mixture is a necessary and important step in the production line. Today, there exists a wide market of methods in which industries can accomplish these goals. Chromatographic analysis of plasma is an extremely useful diagnostic tool. In this section, we present an example of how chromatography was used to analyze disease profiles.