It should make it better. It sounds like he's needs to see a doctor
If it is a broncospasm should the Ipratropium bromide/albuterol nebulizer treatment and/or proair albuterol inhaler and/or combivent inhaler (Ipratropium bromide/salbutamol) make it better or worse? I've read some conflicting things and the neb used to help his o2 sats , I would use it before bipap but now with the heavy co2 , all those treatments seem to make his sats worse by 5%+.