The following panels were recently performed on my pubescent daughter:
https://providers.genedx.com/tests/detail/autism-id-panel-1007
Overall interpretation: “Whole genome chromosomal microarray: “Negative. Whole genome chromosomal microarray analysis did not identify any copy number changes of known clinical significance.”
https://providers.genedx.com/tests/detail/autism-id-xpanded-panel-849
(A particular VUS was identified but isn’t the topic of this post)
Additional comments: “Variants identified by previous testing that do not meet the reporting threshold for this test may be included below. -“
The assessment later lists percentages next each gene in the panel (some 2k+), prefaced like this:
“The following genes were specifically reviewed with the percentage of the coding region covered at >10X by exome sequencing indicated in parentheses:”
The vast majority are (100%). Many in the 80-99% range. A few stragglers ranging between 50-79%.
Then shows up NLGN4Y aka Neuroligin 4 Y-Linked at 12.25% ?
… am I correct in assuming that it is entirely unexpected (impossible?) for a true female to be carrying a Y-linked gene? What am I missing?