My wife and I have 11 month old fraternal twin boys. Twin A has had a host of health issues, and after genetic testing, were told he has a partial duplication of 4q - base pairs 31.3 to 35.2. We're going to see a genetic counselor, and me, my wife, and Twin B are going to be tested.
The only useful information I could find comes from an article on "rarechromo.org" but it's only based on something like 43 cases. I'm wondering what weight I should put, if any, on a study of 43 cases as it seems like an extremely small sample size, and is a mixture of duplication of different portions of 4q. I'm most concerned about long term outlook on developmental delays and intellectual abilities, but don't think there's really much out there to guide me.