What is haemochromatosis and what are the symptoms?
Haemochromatosis or iron overload is Irelands most common genetic condition. Early diagnosis is vital and if untreated can lead to organ damage or premature death. The Irish Haemochromatosis Association estimates there are at least 20,000 undiagnosed cases of Haemochromatosis in Ireland. Haemochromatosis is more common in Ireland than anywhere else in the world, as one in five people carry one copy of the gene and 1 in every 83 Irish people carry two copies of the gene, predisposing them to develop iron overload. This year, the IHA promoted World Haemochromatosis Awareness Week, 1st  7th June 2021, to raise awareness of the condition and its symptoms in order to save lives. Several City and County Councils supported the campaign to light up red several iconic public buildings during World Haemochromatosis Awareness Week, including Dublins Mansion House, the Lord Mayors residence in Dublin, the Dublin Convention Centre, Fingal County Hall, Cork City Hall and Limerick City Hall and Civic Bridges. Commenting on the awareness drive for World Haemochromatosis Awareness Week, Dr Maurice Manning, Chair of the Irish Haemochromatosis Association and who himself has Haemochromatosis says, Ireland has more cases than anywhere else in the world and we want everyone to understand what Haemochromatosis is and how important early diagnosis is. Although we remain in a pandemic, it is important that people dont ignore worrying symptoms, that they talk to their GP and arrange a blood test. Though life-threatening, once diagnosed before organ damage has occurred, Haemochromatosis can be successfully treated and patients go on to live their lives to the full, without any impact.  Professor Suzanne Norris, Consultant in Hepatology and Gastroenterology at St. Jamess Hospital says, Ill-health from Haemochromatosis and the development of serious complications such as cirrhosis can be prevented by simple treatment and life expectancy in treated non-cirrhotic patients is normal. Early diagnosis is therefore critical.  Dr John Ryan, Consultant in Hepatology and Gastroenterology at Beaumont Hospital, comments, 'Ireland has the highest rates of Haemochromatosis in the world. Haemochromatosis is an inherited condition, where the body cannot switch off iron absorption and iron build up leads to life-threatening organ damage. If picked up early enough it is entirely treatable, and individuals may also donate blood through the Irish Blood Transfusion clinics, which is then put to good use.  The Irish Haemochromatosis Association was established over 21 years ago. Voluntary Board Member, Margaret Mullett, has worked tirelessly over many years with the IHA and supports patients and people who are newly diagnosed, through the charitys Helpline. Margaret who is a Dublin-based former chemistry teacher, sadly lost her husband, Dr George Mullet, to the condition. He was diagnosed with Haemochromatosis just six weeks before he died in June 2000, awaiting a heart transplant in the Mater Hospital. All five adult children were then tested and were diagnosed with Haemochromatosis  by a strange coincidence Margaret also tested positive for Haemochromatosis. Margaret and all five siblings have received treatment and are living their lives unaffected by the condition. The public can support the work of the Irish Haemochromatosis Association and its Helpline, by donating via the Text to Donate service, Text IRON to 50300 to donate 4.00 or by making a donation on the charitys website: www.haemochromatosis-ir.com. The Irish Haemochromatosis Association (IHA) is a life-changing medical charity and support group for haemochromatosis patients and their families. Their mission is to raise awareness of haemochromatosis nationwide and promote early diagnosis and treatment of the disorder. The IHA is a registered charity, which has worked for over 21 years to raise awareness of Ireland's most common genetic disorder. They encourage people who are suffering from symptoms such as chronic fatigue, joint pain, diabetes, irregular heartbeat and liver problems to consult their GP. A simple blood test to check a patient's iron levels can confirm or rule out iron overload. Once people are diagnosed, the treatment is simple with regular removal of blood, similar to donating blood. Early detection is vital to avoid organ damage and live a normal health life after treatment. What are the symptoms to look out for:  Unexplained weakness or fatigue  Abdominal pain  Diminished sex drive or impotence  Arthritis particularly if it occurs in the first and second knuckles and/or the ankles  Type 2 Diabetes  Liver disorders  Discolouration or bronzing of skin  Mood swings and irritability  Irregular heart rhythm  Testing  Haemochromatosis can be diagnosed by a blood-based genetic test combined with a test to identify high levels of iron in the blood. This can be organised through your GP. Treatment  The main treatment for Haemochromatosis is venesection. This is where a unit of blood is taken from the patient every week or two until their iron levels are brought down to between 50-100 g/L. When iron levels are reduced, patients are said to be in maintenance and get blood taken approximately every three months.