Can Prunes Prevent Heart Disease in Postmenopausal Women?
Eating prunes every day helps improve cholesterol levels in postmenopausal women. naturally occurring antioxidant-powered phenolic compounds, fiber and other nutrients are thought to play a role.  said lead researcher Shirin Hooshmand, Ph.D., RD, Professor at the School of Exercise and Nutritional Sciences at San Diego State University.In this randomized, controlled study, researchers found that eating 50 grams of prunes (about 5-6 prunes) each day for just 6 months resulted in improved CVD risk biomarkers - including raising the body's "good" cholesterol, known as HDL, and lowering the ratio of total cholesterol to HDL.Eating prunes daily also promoted higher antioxidant capacity and lowered levels of the inflammatory cytokines interleukin-6 and tumor necrosis factor-alpha associated with CVD risk. Notably, body mass index and weight of the study participants were maintained during the trial despite adding prunes to the usual diet.Researchers recruited 48 healthy, postmenopausal women who were divided into three groups - a control group who ate no prunes, and two treatment groups who consumed either 50 grams or 100 grams of prunes daily, throughout the six-month study. All other aspects of the women's diets and lifestyles remained similar to before the study.Various biomarkers of CVD risk were collected at the beginning and conclusion of the study to determine if there were any improvements in those biomarkers among those who consumed prunes.Interestingly, there were some similar positive results among those who ate 50 grams of prunes and those consuming 100 grams - suggesting that adding 5-6 prunes or more into the daily diet may have a positive effect on CVD risk.said Mark Kern, Ph.D., RD, CSSD, Professor of Nutrition at the School of Exercise and Nutritional Sciences at San Diego State University.While the precise mechanisms and specific compounds that contribute to these beneficial effects have yet to be determined, naturally occurring antioxidant-powered phenolic compounds, fiber and other nutrients are thought to play a role.This study demonstrates that prunes may be a promising and convenient addition to the diet to reduce CVD risk and inflammation, while also improving antioxidant capacity.The study adds to a growing body of evidence about the overall health and nutrition benefits of prunes, including bone health.Previous clinical research demonstrates a favorable bone response to prunes among postmenopausal women.Most recently, researchers reported that total bone mineral density increased in a postmenopausal woman with osteopenia after she consumed 50 grams of prunes daily for 16 months. This case study was published in theof this year.Source: Eurekalert